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543 articles for “(DoS)”
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A Case Study & Report on Drug Related Adverse Effect Observed and Addressed during Optimal Therapy by Doctor of Pharmacy, in an Antiretroviral Therapy Ward of a Tertiary care teaching Hospital.
Abstract: In the present case study, a drug related adverse effect is observed and addressed during optimal therapy in Antiretroviral Therapy ward of Rajiv Gandhi Institute of Medical Sciences, Kadapa, Andhra Pradesh, India. As a part of Doctor of Pharmacy profession, Manasa Rekha has identified dose related adverse effect and have taken to the notice of Physician and monitored the dose of drug by using therapeutic drug monitoring parameters and have …
Published in Research and Reviews: A Journal of Medicine · Vol. 8, Issue 1, 2018 · pp. 1–5 Read article
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The Efficacy of Vitamin A Supplement in the Treatment of Scabies
Abstract: Scabies is a debilitating contagious parasitic skin disease caused by a tiny mite (Sarcoptes scabiei) treated with the acaricides. Vitamin A supplementation is indicated in management of parasitic infestations in human. This study aimed to assess the effect of vitamin A supplementation as "add on therapy" on the cure rate and quality of life (Qol) in scabies patients treated either with permethin or benzyl benzoate lotions. A total number of …
Published in Research and Reviews: A Journal of Medicine · Vol. 5, Issue 1, 2015 · pp. 19–26 Read article
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A Prospective Study on Role of Doctor of Pharmacy/Clinical Pharmacist in Identification, Reporting and Minimization of Medication Errors in Drug Dispensary (Outpatient Unit) of an ESI Hospital
Abstract: The aim of present prospective study was to assess the role of clinical pharmacist/doctor of pharmacy in the identification, reporting and minimization of drug errors in dispensary department of ESI Hospital, Bengaluru, India. A prospective, observational, non-interventional study was conducted at the department of ESI Hospital, Bengaluru, for a period of six months from October 2018 to March 2019. All patient-related information was collected as per case record form. Among …
Published in Research and Reviews: A Journal of Medicine · Vol. 9, Issue 3, 2019 · pp. 10–19 Read article
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Histological and Functional Effect of Melatonin on Reproductive System
Abstract: Many experimental studies reported that melatonin has shown to induce reproductive toxicity. The purpose of this review is to discuss the evidence regarding the toxic effect of melatonin on the reproductive system and its possible mechanism of toxicity. Literature included in thisreview showed that an extrinsic dose of melatonin inducespharmaceutical, biochemical and physiological effects on the mammalian reproductive function. Empirical and histological examination of melatonin exposure on reproductive function has …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 9, Issue 1, 2020 · pp. 16–23 Read article
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Heavy Metals Removal by Adsorption Using Aloe barbadensis Miller Leaves Residue Powder for More Sustainable Environment
Abstract: Aloe barbadensis Miller residue from herbal wastes has often proved to be effective in the removal of heavy metals from industrial wastewaters. This study was focused on the adsorption of lead using A.barbadensis Miller residue. The initial concentration of lead ions was varied and the influence of contact time, adsorbent dosage, pH and initial metal concentration on adsorption process were studied. The temperature and agitation speed were kept constant at …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 9, Issue 1, 2019 · pp. 92–98 Read article
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CBD: Wonder Drug of the Future
Abstract: The traditional “wonder drug” in pharmacology is aspirin, well known for its properties of pain control, lowering elevated body temperature, fighting inflammation, and decreasing blood coagulation. Aspirin, as a non-steroidal anti-inflammatory drug (NSAID) is a preventative drug as well as a therapeutic one. The Framingham heart study has concluded that a low dose aspirin regimen (81 mg/day) will help prevent cardiovascular disease and stroke. On the other hand, CBD (cannabidiol) …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 7, Issue 1, 2017 · pp. 1–5 Read article
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Tamoxifen: Role in Breast Cancer Treatment
Abstract: Breast cancer is one of the most common cancers among women worldwide. In the last two decades, there have been various therapies proposed for the treatment and prevention of breast cancer. One of them is targeted hormonal therapy (THT) for the estrogen and its receptor in breast cancer. The synthetic selective estrogen receptor modulator, tamoxifen is in the use for treating, estrogen receptor-positive breast cancer from the last 30 years. …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 5, Issue 1, 2016 · pp. 1–19 Read article
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A Case with T-Cell Large Granular Lymphocyte Leukemia Accompanied with Persistent neutropenia without Anemia and Thrombocytopenia
Abstract: AbstractWe report a case of T-cell large granular lymphocyte (T-LGL) leukemia accompanied with persistent neutropenia without anemia and thrombocytopenia. A 47-year-old man was diagnosed as T-cell large granular lymphocyte leukemia by clinical feature, a persistent increase in the number of peripheral blood large granular lymphocyte and immune his to chemical analysis. He had the recurrent aphthous stomatitis persisting for more than 1 year. He showed neither lymph node swelling and …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 9, Issue 2, 2020 · pp. 24–28 Read article
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Incised Surgical Wound Closure with Sutures and Staples: A Prospective Randomised Trial
Abstract: Increasing knowledge and present time demand in the field of surgery has enabled the development of new techniques of surgical wound closure that are not associated with contamination. The aim is to evaluate the advantages and disadvantages of skin closure with sutures and staples. A prospective randomized trial was carried out on a total of 100 patients divided into two groups of 50 each. Patients were in the age group …
Published in Research and Reviews : Journal of Surgery · Vol. 4, Issue 2, 2015 · pp. 10–14 Read article
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PHD-2 Activation to Stabilize HIF-1α and FASN in Mammary Gland Cancer
Abstract: Activation of prolyl hydroxylase-2 (PHD2) has emerged as an attractive target to counteract tumor hypoxia and thereby uncontrolled cellular proliferation. We utilized an integrated strategy to identify new PHD2 activators using series of in silico tools and in vitro methods. The in silico screening helped to identify 4-ethyl-3-(4-methoxyphenyl)-2,2-dimethyl-2H-chromen-7-yl acetate (BBAP-3), [4-(7-acetyloxy-4-ethyl-2,2-dimethylchromen-3-yl)phenyl]acetate (BBAP-4), 3-(4-methoxyphenyl)-2,2,4-trimethyl-2H-chromen-7-yl acetate (BBAP-5) as an activator, who are structurally similar to KRH102140 (a known activator of PHD2). All …
Published in Research and Reviews: A Journal of Toxicology · Vol. 8, Issue 3, 2018 · pp. 28–33 Read article
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The Effect of Vitamin C on the Reproductive Functions of Paraquat Intoxicated Male Albino Rats (Rattus norvegicus)
Abstract: Paraquat (PQ) is a bipyridylium herbicide applied around trees in Orchids and between crop rows to control broad-leaved and grassy weeds. Its oxidation results in the formation of superoxides and supernitrite species which causes damage to cellular components. Studies have implicated PQ as one of the pesticides that contributes to the reduction in male reproductive functions in humans and animals during exposure. This study, therefore, determined the antioxidant effect vitamin …
Published in Research and Reviews: A Journal of Toxicology · Vol. 4, Issue 3, 2014 · pp. 9–29 Read article
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Arsenic Induced Cytotoxicity Study Against Human Epithelial Carcinoma (HeLa) Cell
Abstract: The present investigation was undertaken to find out the cytotoxic effects of various amounts of arsenic exposure to human epithelial carcinoma (HeLa) cell. Cells were treated with a final concentration (0, 10, 20, 30, 40 and 50 µg/l) of arsenite in 5 ml MEM for 24 h where 0 concentration was considered as control. Cell viability was determined by the trypan blue (TB) exclusion test using hematocytometer and automated BIO-RAD …
Published in Research and Reviews: A Journal of Toxicology · Vol. 5, Issue 1, 2015 · pp. 1–8 Read article
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Alteration in Metabolic Enzymes of Albino Rats under Cadmium Stress and their Modulation by Mentha Piperita
Abstract: Cadmium is a heavy metal posing severe risks to human health without any physiological function in the human body. Cadmium is found regularly in soil, rocks and ores, thus natural exposure is an important aspect, but increasing industrial application has put it in the category of bio-hazardous metals. Anticorrosive agents, stabilizer in PVC products, colour pigments, neutron-absorber in nuclear power plants, the fabrication of nickel-cadmium batteries and Phosphate fertilizers carry …
Published in Research and Reviews: A Journal of Toxicology · Vol. 3, Issue 3, 2013 · pp. 1–4 Read article
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Attenuation of Doxorubicin-induced Hepato- and Nephrotoxicity by Proanthocyanidins from Myrica nagi Bark in Wistar Rats
Abstract: Due to dose-related toxic effects, doxorubicin, a very potent and often used anti-cancer medication, is largely limited. The current research investigated the protective impact of Myrica nagi bark (PMN)-isolated proanthocyanidins on hepato-induced doxorubicin and nephrotoxicity in Wistar rats. The animals were subdivided into six classes of five rats each. Group I got PMN (200 mg/kg, p.o.) for 21 days, Group II received Doxorubicin (DXR) (60 mg/kg, i.p.) once, 48 h …
Published in Research and Reviews: A Journal of Toxicology · Vol. 10, Issue 3, 2020 · pp. 19–28 Read article
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Measurement of Indoor Radon Concentration in a Residential House of Surrey (BC) Canada using LR-115 type II Plastic Detector
Abstract: Indoor radon concentration activity measurement has been considered as a useful parameter in evaluation of health hazards due to radon. The major health hazard is lung cancer attributable to radon in Canada which causes 16% of total lung cancer deaths. The purpose of this study is to determine indoor radon concentration (Bq/m3) and effective annual dose (mSv/yr) in a residential building. Plastic detector LR-115 Type II has been used for …
Published in Research and Reviews: A Journal of Toxicology · Vol. 12, Issue 2, 2022 · pp. 21–29 Read article
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Adverse Drug Effect of Habbe Shifa: A Case Study
Abstract: Traditional systems of medicine are practiced across different parts of India. The major traditional system of medicine in India are termed as AYUSH (Ayurveda, Yoga, Siddha, Unani and Homeopathy)—these systems are in use since centuries and are considered as safe without any side effects. Over the counter medications is also common in the name of herbal products. Generally, these herbal drugs are safe, but if not used on proper traditional …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 8, Issue 2, 2021 · pp. 1–4 Read article
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Gada Nigraha—A Critical Review
Abstract: Ayurvedic classical literature has its own peculiarities and focuses on different aspects such as pathology, pharmaceutical and treatment protocol. Most recent treaties of Rasashastra and Bhaishajya Kalpana are written mainly on the usage of various dosage forms to treat the diseases. Gada Nigraha (12th century) is a compelling treatise of Ayurvedic pharmaceutics and reflections of precedent texts on the contents. This treatise consists of two parts and 604 formulations. Systemic …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 10, Issue 2, 2023 · pp. 22–32 Read article
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Ashaya as Abode: Reconciling Ayurvedic Vata Theory with Intestinal Neurophysiology
Abstract: Background-Ashaya refers to a site or structure within the body where a substance resides. Ashaya refers to the internal sites or structures within the body where various substances reside Commonly, seven Ashayas are described in males, while in females there are eight, while Sharangadhara has described 9 Ashayas. Vatashaya denotes the specific site of Vata Dosha, which is considered the chief among the three Doshas due to its vital role …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 15, Issue 2, 2026 · pp. 12–20 Read article
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Toxicology 4.0: Integrating Artificial Intelligence, Big Data, Health Informatics, and Precision Analytics for Predictive Toxicity Assessment, Real-Time Toxicovigilance, and Personalized Patient Safety
Abstract: Background: Toxicology is undergoing a major transformation, increasingly described as Toxicology 4.0, driven by the integration of artificial intelligence (AI), big data analytics, health informatics, and precision analytics. Conventional toxicity testing is limited by high costs, lengthy timelines, and challenges in translating animal and low-throughput in vitro findings to humans. Aim and Objectives: To comprehensively evaluate the emerging role of Toxicology 4.0 in predictive toxicity assessment, real-time toxicovigilance, and personalized …
Published in Research and Reviews: A Journal of Toxicology · Vol. 16, Issue 2, 2026 Read article
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Microstructural Evolution and Mechanical Performance of Ambient-Cured Fly Ash–Metakaolin Inorganic Polymer Composites Activated by Anhydrous Sodium Silicate Powder
Abstract: Inorganic geopolymer networks offer a low-carbon and sustainable solution to traditional binder systems through the alkali-activation of industrials-grade aluminosilicate material. The present paper focuses on the microstructure development and the mechanical performance of the ambient-cured fly ash – metakaolin inorganic polymer composite activated with solid anhydrous sodium silicate powder. Five inorganic polymer binder combinations were formulated by replacing fly ash with metakaolin at mass fractions of 0%, 10%, 20%, 30%, …
Published in Journal of Polymer & Composites · Vol. 14, Issue 4, 2026 Read article