Search
311 articles for “Metabolism”
-
Garcinia cambogia Use of Weight Loss and Hepatotoxicity: A Review
Abstract: A complex disorder of hunger control and energy metabolism driven by certain biological variables is obesity. This study aims to evaluate the applications of Garcinia cambogia products for appetite suppression and fat burning. This little fruit, which looks a lot like a pumpkin, is marketed and used most frequently these days as a weight-loss supplement. Research has demonstrated that the fruit rind's main organic acid component, (−)-hydroxycitric acid (HCA), and …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 12, Issue 2, 2025 · pp. 08–14 Read article
-
Advancing Asthma Management: The Synergy of Systems Biology, Artificial Intelligence, and Next-Generation Therapeutics
Abstract: Asthma is an inflammatory disorder of the respiratory tract that is chronic and heterogeneous in nature and has various effects on millions of people. Being a chronic inflammatory disease, asthma remains incurable and the major conventional treatments offer limited success due to the mask nature of its pathophysiology. Systems biology/(AI), and next-generation has greatly enhanced knowledge and the management of asthma. The approaches based on gene, transcript, protein, and metabolite …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 14, Issue 2, 2024 · pp. 1–12 Read article
-
Improving Indoor Room Air Conditioning Using PID Control
Abstract: Energy use in building air conditioning contributes significantly to power demand; therefore, in this work, we propose an improved methodology to achieve comfort conditions through PID control assistance. The project develops a mathematical model based on analytical heat transfer equations for comfort conditions by fulfilling the Fanger equation, considering environmental parameters (ambient temperature), metabolic rate, and people’s physical activity (internal heat generation) to reduce power consumption and improve energy efficiency. …
Published in Journal of Refrigeration, Air conditioning, Heating and ventilation · Vol. 12, Issue 1, 2025 · pp. 1–21 Read article
-
Mystery of Grass milk: A Deeper Dive into Quality, Quantity and Economics of Grass-milk in Dairy Cows
Abstract: Consumers perceive ‘grass-fed milk’ as healthier than conventional ones since grass-fed milk contains higher levels of beneficial fatty acids and lower levels of omega-6. The study highlights the nutritional benefits of feeding green grass, in terms of quality, quantity, and farm economics emphasizing its specific influence on the fatty acid profile of milk, including enrichment of omega-3 fatty acids and conjugated linoleic acids. It also delves into the environmental benefits …
Published in International Journal of Nutritions · Vol. 2, Issue 2, 2025 Read article
-
Nutritional Management of Polycystic Ovarian Disease: Integrating Unani and Contemporary Approaches
Abstract: In Unani medicine, dietary management, known as Ilaj bil Ghiza, plays a vital role in restoring humoral balance and maintaining a healthy temperament (mizaj). This principle aligns with modern medical understanding, particularly in conditions, like polycystic ovarian syndrome (PCOS), which is often associated with insulin resistance and obesity. Modifying dietary habits has shown promise in improving both metabolic and reproductive functions in PCOS patients. Unani scholars attribute PCOS to a …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 12, Issue 2, 2025 · pp. 1–6 Read article
-
Exploring the Role of Small Dense LDL-C and Paraoxonase-I Activity in Lipid Profile Alterations in Postmenopausal Women: Evidence from a Population-Based Study in Punjab, India
Abstract: Background: After menopause, women face a higher risk of cardiovascular disease (CVD) because hormonal changes impact how their bodies process fats. This study aimed to explore the relationship between small dense LDL cholesterol (sdLDL-C), lipid profile, PON1 levels, thyroid function, CBC parameters, and cardiovascular risk in postmenopausal women (45–60 years) in Punjab, India. sdLDL-C is more atherogenic than larger LDL particles, while PON1, linked to HDL, offers heart protection. Thyroid …
Published in Research and Reviews: A Journal of Health Professions · Vol. 15, Issue 2, 2025 · pp. 45–49 Read article
-
Study of the response of Fenugreek Seedlings (Trigonella foenum-graecum L.) to some Plant Growth Regulators and Their effect on the production of the active Compound (Trigonelline)
Abstract: The experiment was conducted during the 2022–2023 academic year in the laboratories of the Department of Biology, Faculty of Education for Girls, University of Kufa, to investigate the effects of varying concentrations of gibberellic acid (GA₃) — specifically 0, 2, and 3 ppm — and salicylic acid (SA) (0, 2.5, 5 ppm) as well as the interaction between them on the germination percentage and some growth traits of fenugreek seedlings …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 15, Issue 2, 2025 Read article
-
Role and impact of Dietary Antioxidants on Aging and Lifespan: A Review
Abstract: The effect of an antioxidant-rich diet on aging and lifespan has attracted significant scientific attention, primarily through the lens of the free radical theory of aging (FRTA). This theory suggests that oxidative stress caused by an accumulation of reactive oxygen species (ROS), accelerates aging and contributes to cellular damage. The accumulation of free radicals and the oxidative damage that is induced significantly contribute to the aging process. This imbalance plays …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 15, Issue 2, 2025 · pp. 60–70 Read article
-
Health Hazards of Benzene Exposure Among Petrol Pump Attendants in North Indian Cities
Abstract: Benzene exposure is an undisputed occupational risk, notably among petrol pump attendants who come in contact with fuel vapors. Chronic exposure to benzene is linked to several conditions, such as hematological disorders, respiratory issues, and increased cancer prevalence. This research aims to assess the health effects related to benzene exposure amongst petrol attendants in the northern cities of India. A cross sectional study was conducted at each petrol pump in …
Published in Research and Reviews : Journal of Crop science and Technology · Vol. 14, Issue 2, 2025 · pp. 36–43 Read article
-
Review on Dioscorea alata and its Pharmacological application
Abstract: Dioscorea alata, also known as water yam, is an important crop found worldwide. About 600 different species have been reported worldwide. Many nations, including South America, Africa, Australia, and the southern United States, cultivate D. alata. D. Alata is a member of the Discordance family and has been demonstrated to possess anti-inflammatory, anti-apoptotic, and antioxidant qualities. Dioscorea's metabolites include phenolic chemicals, which reduce sugars, flavonoids, glycosides, saponins, alkaloids, anthraquinones, proteins, …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 12, Issue 2, 2025 · pp. 80–86 Read article
-
Understanding the Impact of GMO on Hormones and Their Effect on Mood: A Review Paper
Abstract: The research evaluates how consuming genetically modified organisms affects endocrine functioning that can potentially lead to mood changes or disorders. This is a systematic review paper that analysed sixty publications before selecting thirty which were obtained from Sciencedirect, Frontiers, Springer, Oxfordacadamic, Cabidigitallibrary, Wileyonlinelibrary, Cambridgeuniversitypress, Scijournals, Mdpi, Metabolismjournal; while using Prisma Flow Diagram as the research tool; acknowledging that human hormonal health risks from GMO consumption remain largely unknown due to …
Published in Research & Reviews : Journal of Food Science & Technology · Vol. 14, Issue 3, 2025 Read article
-
Nano-Therapeutics in Diabetes Mellitus: Revolutionizing Diagnosis, Treatment, and Drug Delivery
Abstract: Diabetes mellitus is a chronic metabolic disorder in which blood glucose concentration remains high over an extended duration, resulting in significant lethal complications, including neuropathy, nephropathy and cardiovascular diseases. However, conventional diabetes management strategies, including insulin therapy and oral hypoglycemic agents, rarely exhibit poor bioavailability, high doses, off target delivery, etc. Nanotechnology has brought the rise of diabetes treatment revolution, by overcoming the challenges present in standard treatment, owing to …
Published in Trends in Drug Delivery · Vol. 12, Issue 2, 2025 · pp. 08–19 Read article
-
Investigating The Alkalizing Potential of Chandanasava For Restoring Acid-Base Homeostasis in Renal Tubular Acidosis: A Computational and In Silico Pharmacological Study
Abstract: Chandanasava, a traditional Ayurvedic formulation, is recognized for its potential alkalizing properties, which may help restore acid-base homeostasis in conditions such as renal tubular acidosis (RTA). This study aims to investigate the active components of Chandanasava and their interactions with key renal target proteins, Pendrin and Carbonic Anhydrase II, which are essential for maintaining acid-base balance. An in silico approach was utilized to explore the pharmacological potential of the phytochemicals …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 3, Issue 2, 2025 · pp. 28–52 Read article
-
Role of Nasya in Pakshaghata: An Evidence-Based Review Study on Its Anatomical Pathway and Therapeutic Action
Abstract: Introduction: Intranasal administration (Nasya), a time-honoured Ayurvedic procedure, offers a unique advantage in treating pathology of neurological and systemic diseases due to its targeted and non-invasive nature. Pakshaghata, a neurological disorder characterized by hemiplegia in ancient Ayurvedic literature, where it is classified as a Vatavyadhi. Methods: By going through all the available literatures and information, this review study explores the concept of Nasya in the context of Pakshaghata management, investigating …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 14, Issue 2, 2025 · pp. 1–8 Read article
-
Nutraceuticals Unveiled: Exploring the Science, Benefits, and Future of Functional Food
Abstract: The rapidly developing subject of nutraceuticals is critically examined in this review, with a focus on its scientific basis, proven health advantages, and possible future applications in the functional food industry. Key bioactive ingredients that contribute to the therapeutics effectiveness of functional foods, including flavonoids, polyphenols, carotenoids, probiotics, and essential fatty acids, have been identified and characterized as a result of recent developments in nutritional science. Both experimental and clinical …
Published in International Journal of Nutritions · Vol. 2, Issue 2, 2025 Read article
-
Pediatric and Geriatric Formulation Tailoring Dosage Form for Age-Specific Needs
Abstract: This comprehensive review addresses the critical challenges and advancements in the formulation of oral medications for pediatric and geriatric populations, who often face unique pharmacokinetic and pharmacodynamic differences. The World Health Organization highlights that nearly 50% of long-term medications are not adhered to, with significant implications for health outcomes. Pediatric patients, due to their developmental stages, and geriatric patients, due to age-related physiological changes, require tailored drug formulations to enhance …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 12, Issue 2, 2025 · pp. 89–103 Read article
-
Innovations in Tuberculosis Management: Advancements in Drug-Resistant TB Treatment and Rapid Diagnostics
Abstract: Tuberculosis (TB) remains one of the deadliest infectious diseases worldwide, exacerbated by the increasing prevalence of drug-resistant strains, such as multidrug-resistant (MDR-TB) and extensively drug-resistant TB (XDR-TB). Despite advancements in first-line and second-line treatments, resistance to conventional antibiotics has complicated therapeutic strategies, necessitating novel approaches. This mini review explores emerging advancements in TB treatment, including gene editing technologies, such as CRISPR, which offer potential for precise targeting of drug-resistant bacterial …
Published in International Journal of Antibiotics · Vol. 2, Issue 2, 2025 · pp. 1–7 Read article
-
Review of Atorvastatin As A Potent Drug For Cardio-Vascular Disease(CVD)
Abstract: Cardiovascular disease (CVD), particularly atherosclerosis, remains the leading cause of death worldwide, significantly burdening public health, especially in Western societies. Metabolic syndrome and arrhythmic complications further exacerbate cardiovascular morbidity and mortality. Among restorative specialists, statins particularly atorvastatin have gotten to central in both the essential and auxiliary anticipation of coronary heart infection (CHD) due to their strong lipid-lowering properties and additional pleiotropic impacts. Atorvastatin, a selective HMG-CoA reductase inhibitor, not …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 3, 2025 · pp. 8–18 Read article
-
Innovations in Targeted Drug Discovery for Personalized Medicine
Abstract: Personalized medicine is revolutionizing modern healthcare by custoizing treatment plans to match an individual’s genetic makeup, protein expression, and metabomlic characteristics. Also referred to as precision medicine, this approach seeks to improve therapeutic outcomes, reduce adverse effects, and make efficient use of healthcare resources. The incorporation of various omics technologies—including genomics, proteomics, transcriptomics, metabolomics, and epigenomics—has greatly advanced our ability to understand disease biology and molecular variations specific to each …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 3, 2025 · pp. 19–41 Read article
-
Trichoderma: beneficial fungus for sustainable agriculture
Abstract: As environmentally beneficial substitutes for chemical pesticides, Trichoderma species are being utilized in agriculture more and more. Disease suppression, increased plant growth, and increased tolerance to environmental stress are just a few advantages they provide. These fungi are used in a wide range of cropping systems and formulations around the world. Their use is growing worldwide, particularly in Asia and Europe. In contemporary crop management, items derived from Trichoderma are …
Published in International Journal of Fungi · Vol. 2, Issue 2, 2025 · pp. 25–29 Read article