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332 articles for “Gene medicine”
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Phytochemical, Pharmacological and Unani Traditional Uses of Mazoo (Quercus infectoria): A Review
Abstract: Quercus infectoria (Family: Fagaceae) generally recognized as gall oak, is a trifling shrub originate in Greece, Asia Minor and Iran is predictably assumed to have enormous therapeutic status. There are two varieties of mazoo; one is solid type with no hole on its surface and another is light weighted hold cavity inside and hole on its surface but solid type is medicinally better. Pharmacologically, various animal and human studies have …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 9, Issue 1, 2020 Read article
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Prevalence of Dysmenorrhea in Different Age Groups
Abstract: Dysmenorrhea (painful menstruation) is one of the major gynecological problems, encountered in women of reproductive age. It accounts for more than 1/4th gynaec patients’ visits to the gynecologist. The pain may be spasmodic or congestive type and occurs in lower abdomen, low back or in the thighs. It starts one or two days before onset of menstruation and continues for two days with same intensity or sometimes the pain decreases …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 1, Issue 1, 2014 Read article
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A General Review of Mucuna Pruriens W.S.R to its effect on Parkinson’s Disease.
Abstract: Mucuna Pruriens is a very famous drug prescribed in classical ayurvedic science in various disorder of Nervous System including Kampavata .In Clinical Practice ,Physician used Levadopa as a Dopamine replacement agent in controlling bradykinetic symptoms apparent in Parkinson disease so used successfully in treatment of Parkinson disease.Kapikacchu(Mucuna Pruriens) is having Balya, Brimhanaha, Vrishya, and Vatahara properties and is a natural source of L-dopa. So, keeping in views of the degenerative …
Published in Research & Reviews : Journal of Herbal Science · Vol. 13, Issue 1, 2024 · pp. 1–6 Read article
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The Next Era of Solid-State Innovation: Beyond Silicon
Abstract: The semiconductor industry is getting close to the physical and economic boundaries of silicon-based technology. A new era of solid-state innovation is beginning. Beyond Silicon: The Next Era of Solid-State Innovation looks at the materials, device layouts, and manufacturing methods that are about to change the way electronics and energy work. The article talks about improvements in wide- and ultra-wide-bandgap semiconductors, two- dimensional materials, and quantum and neuromorphic systems that …
Published in International Journal of Solid State Innovations & Research · Vol. 3, Issue 2, 2025 · pp. 19–23 Read article
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Microsphere and Nanoparticle Drug Delivery Systems: Role of Polymers in Pharmacology
Abstract: Microsphere and nanoscale drug delivery methods have changed the field of pharmacology by making treatment agents more bioavailable, more targeted, and easier to manage. These delivery systems, which are mostly made up of polymers, look like a good way to get around the problems that traditional drug formulations have, like not dissolving well, clearing quickly, and spreading in different places. Plastics are very important in the creation of these improved …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 420–432 Read article
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A study on Antibiotic Resistance: An Analysis of Molecular Mechanisms and Therapeutic Implications
Abstract: Antibiotic resistance (AR) represents one of the most critical existential threats to global public health, rapidly eroding the efficacy of established antimicrobial therapies and portending a return to the pre-antibiotic era. This analysis explores the intricate molecular landscape defining this crisis, focusing specifically on the primary mechanisms of action (MoA) utilized by major antibiotic classes—including cell wall inhibitors, protein synthesis inhibitors, and nucleic acid synthesis inhibitors—and the corresponding, diverse mechanisms …
Published in International Journal of Antibiotics · Vol. 3, Issue 1, 2026 · pp. 9–21 Read article
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Elementary Mechanisms and Therapeutic Approaches for Epilepsy: A Neurodegenerative Impairment
Abstract: The main reason of the epilepsy is both genetic as well as acquired sources. Conventionally developed origins comprise thoughtful brain trauma and difficulties consequential from aforementioned infection. Mostly, the reason of epilepsy is not clear. Seizures may also transpire as a moment of additional health complications, like stroke, head injury, toxic assimilation, or metabolic delinquent. Epilepsy is treacherous when seizure befalls throughout pregnancy. Convinced anti-epileptic medicines upsurge the jeopardy of …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 13, Issue 1, 2023 · pp. 41–46 Read article
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Monoclonal antibodies in targeted cancer therapy advances, resistance mechanisms, and next-gen formats (Bispesifics, ADCs)
Abstract: Breast cancer is one of the leading causes of cancer-related morbidity and death worldwide, which emphasizes the need for more effective and focused treatment strategies. antibody-mediated drug delivery techniques. Specifically, antibody–drug conjugates (ADCs) have emerged as a potential approach that combines the specificity of monoclonal antibodies with the potent cytotoxicity of anticancer drugs. By selectively targeting tumor-associated antigens, ADCs enhance drug accumulation within cancer cells while minimizing systemic toxicity associated …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 17, Issue 2, 2026 · pp. 62–79 Read article
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Exploring Pharmacological Mechanism Of Pteridines And Its Derivatives Against Neurodegenerative Disorders Using Network Pharmacology And Molecular Docking Techniques
Abstract: Objectives: Pteridines have been identified via various research and shown therapeutic efficacy in Neurodegenerative disorders(ND) preclinical models. In the current study, a network pharmacology technique was applied to determine the underlying mechanism of the pteridines' protective effects on ND. Network pharmacology was utilised in order to reveal the interactions between medications and the targets of illnesses, and it is capable of completely articulating the complexity between diseases and medications. The …
Published in Research and Reviews : Journal of Computational Biology · Vol. 11, Issue 03, 2022 · pp. 1–13 Read article
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Computational Screening of Vitex negundo Compounds for Potential Arthritis Therapies in India
Abstract: Objective: Arthritis is a pervasive medical condition that manifests as inflammation and discomfort within the joints. As of September 2021, arthritis has affected an estimated 180 million people in India, making it a substantial public health concern with a considerable impact on individuals' quality of life and healthcare systems. Therefore, using molecular docking, drug-likeness prediction, and ADME analysis, an effort was made to identify natural compounds from Vitex negundo, which …
Published in Research and Reviews : Journal of Computational Biology · Vol. 13, Issue 1, 2024 · pp. 01–18 Read article
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Role of Epigenetic Mechanisms in Lung Fibrosis: Therapeutic Opportunities and Challenges
Abstract: Lung fibrosis poses a serious risk to one's health since it might result in respiratory failure due to an abnormal accumulation of fibrotic tissue in the lungs. Epigenetic mechanisms, such as histone changes, DNA methylation, and non-coding RNAs, closely control gene expression patterns and cellular processes associated with lung fibrosis. Anomalies in DNA methylation patterns connected to changes in gene expression profiles and disturbances in fibrotic signalling pathways are potential …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 2, 2024 · pp. 9–20 Read article
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Plant-Derived Vaccines: A Sustainable Approach to Disease Control for Global Health
Abstract: Plant-based vaccines present a novel and environmentally responsible approach to vaccination, with significant potential for improving both human and animal health. These vaccines are safer and less expensive than traditional vaccine manufacturing methods because they use genetically modified plants to create antigens that elicit an immune response. Plant-based systems offer a potential remedy for traditional vaccines' high production costs and environmental impact, which are growing problems. Plant-derived vaccines have shown …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 15, Issue 1, 2025 · pp. 17–20 Read article
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Production of Levan, A Potential Low Calorie Sweetener From Low Cost Substrates
Abstract: Levan is a biocompatible and bioactive bio-polymer with good rheological and medicinal properties. Due to its high cost, it is beyond reach of commons. The current study deals with levan production using regional low cost substrates as carbon source which will help to reduce its cost. 10 isolates were obtained from a novel source i.e. soil from jaggery preparation area, from which three levan producing isolates were selected and identified …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 9, Issue 2, 2019 · pp. 8–18 Read article
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Concept of “Tabi‘at” with a Brief Description of Its Synchronised Activity
Abstract: Unani System of medicine stands to maintain the health and cure the disease with an emphasis on prevention is better than cure. The ancient Unani philosopher-physicians put forth the concept of “Tabi‘at” as the power endowed by nature to everyone to govern the task of survival. Tabi‘at is the Sayyad-ul-Quwa (supreme power) under which many other subsequent powers work. In general, Tabi‘at regulates all physiological functions in the body, broadly …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 9, Issue 2, 2022 · pp. 5–10 Read article
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Primary Dysmenorrhea: A Review with Special Reference to Unani Concepts
Abstract: Dysmenorrhea is potentially the most common and most underdiagnosed gynecologic condition. It is characterized by crampy lower abdominal pain radiating to back and thigh. Nausea, vomiting, headache and diarrhea are frequent accompanying symptoms. An excess or imbalance of prostaglandins, vasopressin, and chemical substances derived from phospholipids play an important role in generating primary dysmenorrhea symptoms, although exact pathology is still difficult to understand. An estimated 10–30% of all working or …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 1, Issue 1, 2014 Read article
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Molecular Docking of Arjuna Tree Phytocompounds for Ischemic Heart Disease
Abstract: Heart disease is a serious condition that can be caused by several lifestyle changes and sometimes genetic problems. The primary protein component of apolipoprotein is the LDL receptor, which indicates that a reduction in LDL levels can reduce the risk of ischemic heart disease. Apolipoprotein levels are associated with increased levels of ischemic heart disease. Using ADMET analysis, drug likelihood prediction, and molecular docking, this work attempted to find natural …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 3, Issue 1, 2025 · pp. 42–52 Read article
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Preparation, Categorization and Anticancer Study of Novel Bicyclic Compounds from Various Types for (Five and Six)- Membered Ring
Abstract: The characteristics of ring systems change in the presence of functional groups, but in some cases, elements that are considered functional groups can be classified within the same ring. Compounds that contain only carbon and hydrogen are called homogeneous rings, while those that contain other elements are called heterogeneous rings. The atom substituted in place of the carbon atom is referred to as a heteroatom. Generally, the heterocyclic atom is …
Published in Journal of Catalyst & Catalysis · Vol. 12, Issue 3, 2025 · pp. 18–30 Read article
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Adverse Drug Reactions: A Global Health Challenge
Abstract: Adverse drug reaction (ADR) is an unfavorable event with a causal connection to the medication. It is an undesirable event occurred by a pharmacological substance. They are a major cause of Mortality all over, they are classified into augmented, chronic, bizarre, Delayed based on the severity of the damage they caused The primary causes of adverse drug reactions (ADRs) are drug overdose, drug– drug interactions, genetic variations, and individual characteristics …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 2, 2026 · pp. 01–06 Read article
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Factors Influencing Institutional Child Birth among Women in Aynalem Kebelle, Mekelle, Tigray, Ethiopia
Abstract: Giving birth is the most critical part of pregnancy intervention for improving maternal and child health in Ethiopia with maternal mortality ratio of 673 per 100,000 live births. The majority of births are delivered at home and the proportion of deliveries assisted by skilled attendant is very low. The present study assessed the factors influencing institutional child birthing among women in Aynalem Kebelle, Mekelle, and Tigray, Ethiopia.A community-based cross-sectional study …
Published in Research and Reviews: A Journal of Medicine · Vol. 6, Issue 2, 2016 · pp. 21–27 Read article
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A Typical Case of Asherman Syndrome (Fritsch Syndrome) due to Prolonged Retained Fragment of Cu-T in Myometrium
Abstract: Asherman or Fritsch syndrome is also known as intrauterine adhesions. It can lead to partial or complete dysfunction of the endometrium. It affects women of all races and ages equally suggesting no underlying genetic predisposition for its development. The incidence is 40% after D and C. It is mostly due to vigorous curettage of endometrium causes scarring and occlusion in the uterine cavity or it may also be due to …
Published in Research and Reviews: A Journal of Medicine · Vol. 7, Issue 1, 2017 · pp. 10–12 Read article