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304 articles for “chronic”
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Machine Learning-Driven Early Prediction and Prevention of Obesity and Overweight
Abstract: Obesity has become a global health concern, with its prevalence reaching alarming levels in recent years. By classifying obesity-level, healthcare professionals can assess an individual's risk and develop appropriate treatment and prevention strategies. Healthcare professionals can customize interventions and create personalized treatment plans based on individual needs. This paper delivers a system provides an overview of obesity, highlighting the importance of accurate and standardized categorization for effective management and treatment …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 14, Issue 2, 2024 · pp. 31–40 Read article
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Microsphere-Based Drug Delivery: A Critical Review of Innovations and Applications
Abstract: Microspheres have emerged as a revolutionary approach in pharmaceutical sciences, offering controlled and targeted drug delivery with improved bioavailability, stability, and patient compliance. These spherical carriers, ranging from nanometers to micrometers in size, can encapsulate both hydrophilic and hydrophobic drugs, enabling sustained and site-specific release. The development of microspheres has been significantly driven by the need to enhance drug efficacy while minimizing systemic side effects. This review provides a comprehensive …
Published in Trends in Drug Delivery · Vol. 12, Issue 2, 2025 · pp. 52–59 Read article
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Rheumatoid Arthritis and Stem Cell Therapies Perspectives for It
Abstract: Rheumatoid arthritis (RA) is a chronic autoimmune disorder characterized by systemic inflammation, primarily affecting synovial joints, leading to joint destruction and systemic complications. The pathogenesis involves immune system dysregulation, autoantibody production, and enzymatic imbalances. Enzymes, including matrix metalloproteinases (MMPs), serine proteases, and kinases, play crucial roles in these processes. Their dysregulation contributes significantly to disease progression through the imbalance of pro-inflammatory cytokines, oxidative stress, and extracellular matrix (ECM) degradation. MMPs, …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 15, Issue 2, 2025 Read article
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The Transformation of Surgery: From Ancient Techniques to Modern Advancements
Abstract: Surgery has long been a cornerstone of medical practice, evolving from ancient rudimentary techniques to advanced, life-saving procedures. This article explores the critical role surgery plays in modern medicine, examining its significance in diagnosis, treatment, and patient care. It delves into how surgical interventions have become essential in managing a wide array of conditions, from acute trauma to chronic diseases, and highlights the advancements in surgical technology and techniques, such …
Published in Research and Reviews : Journal of Surgery · Vol. 14, Issue 2, 2025 · pp. 19–41 Read article
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Role and impact of Dietary Antioxidants on Aging and Lifespan: A Review
Abstract: The effect of an antioxidant-rich diet on aging and lifespan has attracted significant scientific attention, primarily through the lens of the free radical theory of aging (FRTA). This theory suggests that oxidative stress caused by an accumulation of reactive oxygen species (ROS), accelerates aging and contributes to cellular damage. The accumulation of free radicals and the oxidative damage that is induced significantly contribute to the aging process. This imbalance plays …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 15, Issue 2, 2025 · pp. 60–70 Read article
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Electrospun Nanofibers for Biomedical and Pharmacological Applications
Abstract: In biological and pharmaceutical sectors, nanofibers which have unique properties including a lot of surface area, tunable porosity, and high mechanical strength are very fascinating and may be made flexibly and effectively by electrospinning. More and more in biosensors, tissue engineering, drug delivery, wound healing, and medication delivery are these electrospun nanofibers being used. They may fundamentally alter the way healthcare is administered. Advanced medical applications benefit from fibres' ability …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 375–387 Read article
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Health Hazards of Benzene Exposure Among Petrol Pump Attendants in North Indian Cities
Abstract: Benzene exposure is an undisputed occupational risk, notably among petrol pump attendants who come in contact with fuel vapors. Chronic exposure to benzene is linked to several conditions, such as hematological disorders, respiratory issues, and increased cancer prevalence. This research aims to assess the health effects related to benzene exposure amongst petrol attendants in the northern cities of India. A cross sectional study was conducted at each petrol pump in …
Published in Research and Reviews : Journal of Crop science and Technology · Vol. 14, Issue 2, 2025 · pp. 36–43 Read article
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Crossroads of Ecology and Medicine: Evaluating Pollutant-Induced Risks to Biodiversity and Human Health
Abstract: Environmental pollution has emerged as a central challenge at the crossroads of ecology and human medicine. The rapid pace of industrialization, urbanization, and agricultural intensification has led to an unprecedented release of pollutants into the air, water, and soil—triggering cascading effects on ecosystems and human health. Pollutants such as particulate matter, heavy metals, pesticides, microplastics, endocrine-disrupting chemicals, and persistent organic pollutants not only degrade biodiversity but also exert multifaceted health …
Published in International Journal of Environmental Noise and Pollution Control · Vol. 3, Issue 1, 2025 · pp. 41–53 Read article
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AI Application in the Creation of Medications for COPD
Abstract: The crippling lung condition known as chronic obstructive pulmonary disease (COPD) is typified by a continuous restriction of airflow, which results in increased respiratory dysfunction and a reduced quality of life. The rising incidence of COPD worldwide emphasizes the pressing need for innovative pharmaceutical approaches to address the illness. Even though COPD care has advanced significantly, most current medications concentrate on symptom relief rather than disease change. This gap in …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 2, 2025 · pp. 01–05 Read article
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Advances in Polymer Chemistry for Biomedical Applications: A Focus on Wearable Therapeutic Devices
Abstract: Polymer chemistry has significantly contributed to the evolution of biomedical materials, particularly in the development of wearable therapeutic devices. The combination of biocompatible polymers with advanced composite materials has led to the creation of flexible, durable, and patient-friendly medical support systems. These innovations have transformed healthcare by providing non-invasive and comfortable solutions for managing chronic pain and musculoskeletal disorders. Recent advancements in polymer chemistry have focused on three key areas: …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 · pp. 7–15 Read article
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Implementation of Artificial Intelligence Technology in Tele Medicine
Abstract: The practice of medicine across locations by the prudent application of information and communication technology is known as telemedicine. As a result of the COVID-19 epidemic, telemedicine has experienced exponential growth on a global scale. Artificial intelligence has the potential to enhance and broaden the scope of telemedicine, opening up countless opportunities for creating solutions for particular medical need. AI in telemedicine has the potential to significantly aid in the …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 15, Issue 3, 2025 · pp. 41–50 Read article
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In-Silico Docking of Rubia cordifolia Phytocompounds as Potential MMP-2 Inhibitors for Varicose Vein Management
Abstract: Varicose veins are one of the most common disorders, affecting the vein structure and function of lower limbs, yet there has been no absolute cure found yet. One of the underlying causes for worsening of the condition is the proteolytic activity of MMPs which are a group of enzymes that affect the extracellular matrix (ECM) surrounding the affected veins. Phytocompounds of Rubia cordifolia (Manjishta) were docked against the MMP-2 protein …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 3, Issue 2, 2025 · pp. 31–42 Read article
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Nano-Therapeutics in Diabetes Mellitus: Revolutionizing Diagnosis, Treatment, and Drug Delivery
Abstract: Diabetes mellitus is a chronic metabolic disorder in which blood glucose concentration remains high over an extended duration, resulting in significant lethal complications, including neuropathy, nephropathy and cardiovascular diseases. However, conventional diabetes management strategies, including insulin therapy and oral hypoglycemic agents, rarely exhibit poor bioavailability, high doses, off target delivery, etc. Nanotechnology has brought the rise of diabetes treatment revolution, by overcoming the challenges present in standard treatment, owing to …
Published in Trends in Drug Delivery · Vol. 12, Issue 2, 2025 · pp. 08–19 Read article
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Role of Inflammatory Markers and Lipid Abnormalities in Glycemic Dysregulation Among Type 2 Diabetics
Abstract: Background: Diabetes mellitus (DM) is a chronic metabolic disorder characterized by systemic inflammation and associated with various complications in multiple organs. Type 2 diabetes mellitus (T2DM) specifically involves insulin resistance, hyperglycemia, and inflammatory responses. This study investigates the levels of various inflammatory markers and their correlation with glycaemic control in T2DM patients. Objective: To evaluate the levels of inflammatory markers (including NLR, PLR, SII, SIRI, CRP, IL-6, TNF-α, TGF-β, MCP-1, …
Published in Emerging Trends in Metabolites · Vol. 2, Issue 2, 2025 Read article
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Electroconvulsive Therapy in the Management of Schizophrenia: A Systematic Review in Emergency Nursing Practice
Abstract: Electroconvulsive therapy (ECT) is a well-established treatment for various psychiatric disorders, including schizophrenia, particularly in cases where patients are resistant to conventional treatments. Schizophrenia, a chronic and severe psychiatric disorder, often presents with a combination of positive symptoms (such as hallucinations and delusions), negative symptoms (such as social withdrawal and emotional blunting), and cognitive impairments. While antipsychotic medications are the primary treatment, approximately 20–30% of individuals with schizophrenia do not …
Published in International Journal of Emergency and Trauma Nursing and Practices · Vol. 3, Issue 1, 2025 · pp. 43–48 Read article
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Emerging Therapies in Respiratory Tract Infections: Current Advances and Future Perspectives
Abstract: The impact of respiratory tract infections (RTI) as a global public health problem continues to be high morbidity and mortality rates. The development of novel therapeutic approaches stemmed from the fact that conventional treatment strategies, antibiotics, antivirals, antifungals etc. have become increasingly ineffective because of rise of antimicrobial resistance (AMR). Next generation therapies, such as novel antimicrobial agents, host directed therapies and novel drug delivery systems have come on the …
Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 2, 2025 · pp. 17–25 Read article
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Towards a Safer Nuclear Future: Safety, Security, and Proliferation
Abstract: The worldwide spread of nuclear technology creates both possibilities and hazards, thereby requiring a thorough strategy for nuclear safety, security, and non-proliferation. This paper looks at the linked issues of stopping nuclear accidents, protecting materials from nefarious use, and controlling the proliferation of nuclear weapons. It investigates the efficacy of treaties like the Nuclear Non- Proliferation Treaty (NPT) and looks at international regulatory systems, including those run by the International …
Published in Journal of Nuclear Engineering & Technology · Vol. 15, Issue 2, 2025 · pp. 34–47 Read article
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Immunological and Genetic Markers of Rheumatoid Arthritis Among Women in North India: A Case-Control Study
Abstract: Background: Rheumatoid arthritis (RA) is an autoimmune disease systemically afflicting women marked by chronic inflammation around the involved joints leading to joints destruction. It has both endocrinological and immunological associations as well as genetic associations but data pertaining to women of North India is scanty. Objective: This case-control study was done to evaluate the presence and significance of major immunological and genetic markers of RA in North Indian women with …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 3, Issue 2, 2025 · pp. 1–10 Read article
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Drug Utilisation and Cost Analysis in End-Stage Renal Disease Patients: A Prospective Observational Study
Abstract: Chronic Kidney Disease (CKD) is a condition in which the kidneys are damaged and unable to efficiently remove waste and excess fluid from the blood. Dialysis serves as a treatment for CKD by artificially carrying out the kidney’s filtering functions. This prospective observational cross-sectional study was conducted to evaluate drug utilization patterns, economic burden, and health-related quality of life (HRQoL) among patients with end-stage renal disease (ESRD) undergoing dialysis. Over …
Published in Research and Reviews: A Journal of Health Professions · Vol. 15, Issue 2, 2025 · pp. 1–12 Read article
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Polymer Chemistry in Sustained-Release Herbal Composites: Designing a Stable Euphorbia tithymaloides Topical System with Phospholipid and Polymer Matrices
Abstract: Polymer chemistry enables the stabilization and sustained release of herbal actives, critical for topical therapeutic applications. This study explores a novel process for preparing a stable, sustained-release topical composition of Euphorbia tithymaloides, leveraging polymer-based systems. Ethanolic extract (50 mg) of the plant, rich in unstable sugar moieties (e.g., D-ribose) and sterols (e.g., stigmasterol), is encapsulated within a phospholipid matrix of phosphatidylcholine (50–100 mg) and cholesterol (50–100 mg). This lipid-polymer complex, …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 165–171 Read article