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474 articles for “Clinical study”
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Assessment of Polycystic Ovarian Syndrome with Emphasis on Imaging Modalities
Abstract: Polycystic Ovarian Syndrome (PCOS) is a higly prevalent hormonal disorder that affects women during their reproductive age. It is linked to a wide range of health concerns ,including disturbances in reproductive functions, metabolic abnormalities and an increased risk of cardiovascular diseases. Ultrasonography plays a crucial role in identifying polycystic ovarian morphology, which constitutes one of the key diagnostic criteria under the Rotterdam consensus. This prospective cross-sectional observational study was conducted …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 16, Issue 1, 2026 Read article
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A Dual-Model Deep Learning Framework for Early Alzheimer’s Detection Using Clinical Data and Neuroimaging with Architectural Performance Analysis
Abstract: Alzheimer’s disease (AD) poses a significant global health challenge due to its increasing prevalence and the absence of definitive cures. Early diagnosis is crucial for effective intervention and management. This study presents a dual-model deep learning framework for the early detection and classification of AD using both structured clinical data and neuroimaging datasets. Model 1 utilizes a greedy layer-wise autoencoder approach applied to structured data, achieving optimal binary classification accuracy …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 16, Issue 1, 2026 · pp. 1–12 Read article
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The Evaluation of the Light Parameters and Pleural Fluid Cholesterol to Determine the Differences Between Exudative and Transudative Pleural Discharge
Abstract: Background: Pleural effusion occurs when an imbalance between pleural fluid production and absorption leads to the accumulation of excess fluid in the pleural cavity. Pleural effusions are commonly classified into two types: transudative or exudative, depending on the underlying mechanism of fluid formation. While transudates typically result from systemic factors like heart failure or liver cirrhosis, exudates are usually caused by local factors such as infection, malignancy, or inflammation. Differentiating …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 14, Issue 3, 2024 · pp. 30–35 Read article
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A study on IoT and AI for Predictive Modeling and Control of Infectious Disease Transmission
Abstract: Background: The global response to novel and recurring infectious diseases is frequently hindered by surveillance systems that are slow, siloed, and reactive. Traditional epidemiology relies on retrospective analysis of clinical reports, often missing the critical early phase of autocatalytic spread. The urgency of modern public health necessitates a shift toward real-time, predictive intelligence. Methods: This study investigates the development and deployment of a synergistic paradigm integrating the Internet of Things …
Published in International Journal of Pathogens · Vol. 2, Issue 2, 2025 Read article
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The Role of Natural Products in Antiviral Drug Discovery: Insights into Mechanisms and Therapeutic Potential
Abstract: Drug discovery has always relied heavily on natural sources, especially when it comes to creating antiviral medications. This review explores the therapeutic potential of various natural products, including plant extracts, marine compounds, and microbial metabolites, in the fight against viral infections. We examine the mechanisms of action by which these natural compounds exert their antiviral effects, including direct inhibition of viral replication, modulation of host immune responses, and interference with …
Published in International Journal of Virus Studies · Vol. 1, Issue 2, 2024 · pp. 36–47 Read article
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Role of the Surgical-Ward Nurse in Identifying, Escalating, and Managing Postoperative Anastomotic Leak in Colorectal Patients: A Narrative Synthesis in an Australian Nursing Perspective
Abstract: Purpose: Postoperative colorectal anastomotic leak (AL) is one of the most feared complications after colorectal surgery because of its association with sepsis, reoperation, mortality, prolonged hospital stay, delayed adjuvant therapy, and permanent stoma formation. This narrative practice review outlines the frontline role of surgical-ward nurses in the early identification, escalation, and interim management of AL within the Australian acute-care context. Methods: A narrative synthesis of contemporary consensus statements, systematic reviews, …
Published in Research and Reviews : Journal of Surgery · Vol. 15, Issue 1, 2026 · pp. 7–12 Read article
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Comparison of Several Clinical Scoring Systems in Predicting the Outcome of Variceal Bleeding
Abstract: Background: Stratification of variceal bleeding patients into high-risk and low-risk group is very important to guide them through the suitable clinical pathway and to save the medical costs. We purposed to find out the best scoring system in the prediction of rebleeding and death after variceal bleeding by comparing four clinical scoring systems(clinical Rockall score, complete Rockall score, AIMS65 score, Child-Pugh score) which seemed to be applicable and simple. Method: …
Published in Research and Reviews: A Journal of Medicine · Vol. 15, Issue 2, 2025 Read article
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Effectiveness of Evidence-Based Pediatric Nursing Practices on Clinical and Developmental Outcomes in Children: A Comprehensive Systematic Review
Abstract: Evidence-based pediatric nursing practices are essential for improving health outcomes among children by integrating clinical expertise with the best available research evidence and patient-centered care approaches. This systematic review examines the effectiveness of evidence-based pediatric nursing interventions on clinical and developmental outcomes in children across various healthcare settings. A comprehensive search of databases including PubMed, CINAHL, Scopus, and the Cochrane Library was conducted for studies published between 2016 and 2026. …
Published in International Journal of Evidence Based Nursing And Practices · Vol. 4, Issue 1, 2026 Read article
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Comparison of Knowledge Perceived by Final Year Dental Students for a Lesson on the Apical Barrier in the Premature Root by Clinical Case Demonstration as Compared to the Didactic Teaching Method
Abstract: The present dental education is using didactic teaching method, which is teacher-centered with minimal or no active participation from the students. Case-based learning (CBL) is defined as learning that is based upon description of a patient’s problems, analysis and interpretation of all the relevant data obtained from history, examination and investigations and planning for further management of patient. The goal of CBL is to prepare students for clinical practice, by …
Published in Research and Reviews: A Journal of Dentistry · Vol. 15, Issue 2, 2024 · pp. 1–7 Read article
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Zebrafish in Drug Research: Decoding Biological Mechanisms and Finding Novel Therapeutic Targets
Abstract: The zebrafish, scientifically known as Danio rerio, is a powerful model organism in biological research because of its favorable traits, which include rapid development, genetic tractability, and transparent embryos. Zebrafish were first identified for their use in studies of vertebrate development, but they have since spread to a variety of disciplines, such as pharmacology, clinical research as a disease model, and most notably, drug development. Zebrafish have emerged as a …
Published in Research and Reviews: A Journal of Toxicology · Vol. 15, Issue 3, 2025 · pp. 1–8 Read article
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Panoramic review on Sida rhombifolia L.
Abstract: Sida Rhombifolia is also called Bala and is a well-known Ayurvedic herbal preparation used to treat inflammation, pain and neurological disorders. Literature calls Bala as Sida cordifolia, Sida, root powder acute, Sida cordata or Sida Rhombifolia subsp. retusa to achieve clinical efficacy of standardization of ksheerBala thailam Balamulacherna is essential.The objective of the study is to authenticate the pharmacognostic standards of Sida Rhombifolia root powder. Sida Rhombifolia was standardized with …
Published in International Journal of Pathogens · Vol. 1, Issue 1, 2024 · pp. 20–32 Read article
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Early Detection of Alzheimer’s Disease Using Machine Learning Techniques
Abstract: Alzheimer's Disease (AD) is a progressive neurodegenerative condition impacting a large global population. Detecting AD early is critical for timely intervention and effective management. Conventional diagnostic approaches involve cognitive assessments and neuroimaging, which are often lengthy, costly, and prone to human error. In this paper, we propose a novel approach for early detection of AD using machine learning techniques applied to multimodal data, including neuroimaging, cognitive assessments, and biomarkers. Our …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 14, Issue 2, 2024 · pp. 32–43 Read article
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Effectiveness of Habb-e-Suranjan and Roghan-e-Farfiyun in the Management of Waja-ul-Rukba (Knee Pain): A Review
Abstract: Introduction: Knee osteoarthritis is a painful condition that represents the degeneration of the cartilage and osteophyte formation in the knee joint, which affects millions of people worldwide. According to the Unani claimed text, accumulation of “madda” (substance) in joints, which is neither absorbed nor expelled, is due to the absence of Quawwat-e-Jazibah (power of absorption) and Quawwat-e-dafia (power of expulsion). Unani medicine presents a promising approach for managing knee osteoarthritis …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 12, Issue 2, 2025 · pp. 7–12 Read article
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Study to Assess the Effectiveness of Teaching Program on Knowledge Regarding Management of Patients with Regenerative Orthopedics Procedures Among Orthopedic Nurses at Selected Orthopedic Departments
Abstract: Regenerative therapy is an emerging treatment approach in medical science. It focuses on the use of stem cell therapy, biological treatments, tissue engineering, platelet-rich plasma, prolotherapy, and nutraceutical supplements to replace or restore dysfunctional structures or organs. Regenerative therapy emphasizes the body’s natural healing process; it supports physiological healing mechanisms and repairs damaged tissues. It is a minimally invasive approach with expanding applications across various medical fields, including surgery, degenerative …
Published in International Journal of Orthopedic Nursing and Practices · Vol. 3, Issue 2, 2025 · pp. 7–11 Read article
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Impact of Diet and Certain Functional Foods in Type-II Diabetes Management
Abstract: Global health is greatly challenged by type 2 diabetes mellitus (T2DM), whose management mostly depends on dietary and lifestyle changes. This review study looks at how important diet and certain functional items are for managing type 2 diabetes. It offers a thorough summary of current scientific discoveries and clinical investigations that emphasize the contribution of dietary decisions and functional foods to better glycemic control, increased insulin sensitivity, and decreased risk …
Published in Research & Reviews : Journal of Food Science & Technology · Vol. 13, Issue 1, 2024 · pp. 9–15 Read article
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Ayurvedic Management of Vatika Pakshavadha (Hemiplegia): A Case Study
Abstract: Background: Pakshavadha, described in Ayurveda under the category of Vāta Vyādhi, is a neurological disorder caused by aggravated Vāta doṣa affecting one half of the body. Clinically, it is correlated with hemiplegia or post-stroke neurological deficits, particularly following ischemic cerebrovascular accidents. Stroke remains a leading cause of mortality and disability worldwide, often leaving patients with residual weakness, gait disturbances, and impaired speech despite modern rehabilitation. Ayurveda offers a holistic approach …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 13, Issue 2, 2026 Read article
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Solubility Enhancement Technique for Verapamil by Solid Dispersion Method
Abstract: By creating a solid dispersion, this study aimed to address the limitations of the traditional solid dosage form of verapamil, including its low bioavailability and restricted clinical efficacy. In order to alter the drug's release and improve its solubility, verapamil solid dispersion was created using the Solvent Evaporation Method and Fusion Method. The physical state of the solid dispersed verapamil was determined using saturation solubility testing and dissolution studies. Verapamil …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 17, Issue 1, 2026 · pp. 94–99 Read article
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Deep Learning Applications in Bone Fracture Detection for Improved Radiographic Diagnostics
Abstract: Bone fracture detection is a critical aspect of medical diagnostics, traditionally relying on manual interpretation of radiographic images by experienced radiologists. This discipline has undergone a revolution with the introduction of machine learning (ML), which can improve accuracy, shorten diagnosis times, and lessen human error. This study investigates the use of different machine learning methods to enhance and automate the identification of bone fractures in radiography pictures. We utilized a …
Published in International Journal of Optical Innovations & Research · Vol. 2, Issue 2, 2024 · pp. 17–22 Read article
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Evaluation of Patient-Specific Quality Assurance for RapidArc Treatment Delivery Using Dose Volume Histogram
Abstract: This study aims to evaluate the application of dose volume histogram (DVH) metrics within the patient-specific quality assurance (PSQA) protocol in various sites for RapidArc treatment delivery. Forty patients were included in this study, of which twenty each Head and Neck (H&N) and Pelvis Rapid Arc plans were evaluated. Octavius 4D 1500 detector array with vented parallel plate ion chambers was used for this study, which reconstruct the pre-treatment measured …
Published in Journal of Polymer & Composites · Vol. 11, Issue 7, 2023 · pp. 14–22 Read article
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Periodontitis and Rheumatoid Arthritis
Abstract: This comprehensive review delves into the complex interplay between Periodontitis and Rheumatoid Arthritis, aiming to unravel the underlying mechanisms and shared inflammatory pathways that connect these seemingly distinct conditions. The review examines a wealth of current research, exploring how chronic periodontal inflammation may contribute to the development and progression of RA and vice versa. Furthermore, the review critically evaluates the clinical implications of this interrelation, emphasizing the need for interdisciplinary …
Published in International Journal of Tropical Medicines · Vol. 1, Issue 1, 2024 · pp. 31–39 Read article