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208 articles for “significance in biology”
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Pharmacodynamics and Drug–Receptor Interactions: Integrating PK/PD Modeling with Modern Drug Development
Abstract: Understanding drug action requires an integrated perspective of pharmacodynamics and pharmacokinetics, which together determine therapeutic efficacy and safety. This review provides a comprehensive overview of the mechanisms underlying drug action, with particular emphasis on drug–receptor interactions and their role in modulating physiological responses. Drugs exert their effects primarily through interactions with specific biological targets, including receptors, enzymes, ion channels, and transporters, resulting in a spectrum of desired and adverse outcomes. …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 2, 2026 Read article
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A Comprehensive Review on Neturaceuticals in Alzheimer's and Neurodegenerative Disease an Cognitive Enhancement
Abstract: Neurodegenerative diseases, including Alzheimers disease (AD), Parkinsons disease (PD), and related cognitive disorders, represent a significant and growing public health challenge, particularly in aging populations. Despite advances in pharmacological treatments, therapeutic options for cognitive decline and neurodegeneration remain limited. Recent interest has shifted towards nutraceuticals— bioactive compounds derived from food or natural sources—as promising adjuncts or alternatives in the management of these conditions. This review examines how nutraceuticals can help …
Published in International Journal of Brain Sciences · Vol. 2, Issue 1, 2025 · pp. 1–9 Read article
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Leveraging Full Stack Data Science for Healthcare Transformation: An Exploration of the Microsoft Intelligent Data Platform
Abstract: The rapid progress of the Fourth Industrial Revolution has been largely driven by the evolution of artificial intelligence (AI), with notable contributions from technologies such as Generative Pre-trained Transformers (GPT). This revolution has seen the convergence of physical, digital, and biological technologies, leading to transformative impacts across various sectors. Data science, serving as a crucial enabler, has enabled the development of intelligent value chains. However, the application of data science …
Published in Journal of Advanced Database Management & Systems · Vol. 11, Issue 3, 2024 · pp. 1–8 Read article
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Recent Advances in Quality Control and Quality Assurance: Enhancing Pharmaceutical Product Integrity and Compliance
Abstract: The pharmaceutical industry is undergoing a paradigm shift driven by stringent regulatory expectations and the demand for high-quality, safe, and efficacious drug products. Quality Control (QC) and Quality Assurance (QA) serve as the two foundational pillars that ensure pharmaceutical integrity from raw material acquisition through to product release. Traditional QC and QA practices, while effective, have been challenged by complex formulations, biologics, and personalized medicine, requiring innovative methodologies and technologies. …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 2, 2025 · pp. 54–62 Read article
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Advancements in Nanotechnology and Biosensor Integration for Detection and Treatment of Alice in Wonderland Syndrome
Abstract: Alice in Wonderland Syndrome (AIWS) is an uncommon neurological condition characterized by profound distortions in perception. Individuals with AIWS experience altered body image and spatial awareness, often perceiving objects, surroundings, or even their own body as being unusually large, small, or distorted. The condition presents a unique challenge for both diagnosis and management due to its elusive and varied symptoms. This paper explores how advancements in nanotechnology and biosensor integration …
Published in Nano Trends – A Journal of Nano Technology & Its Applications · Vol. 26, Issue 3, 2024 · pp. 1–12 Read article
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Unlocking Wellness by Ayurveda with Contrasting Modern Medicine
Abstract: In the modern world, we are so subordinate to drugs that we are unable to imagine a single day without them. Like smartphones, we are also addicted to pharmaceuticals, which significantly impact our lives. Constant utilization of medicine makes resistance and dependence on the medicament. It moreover has diverse side effects that cause various health hazards. As people become aware of this, the utilization of herbal remedies has expanded worldwide. …
Published in Research and Reviews: A Journal of Medicine · Vol. 14, Issue 3, 2024 · pp. 16–20 Read article
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Exploring Carbon Nanotubes in Nanotechnology: Functional Properties, Surface Modifications, and Biomedical Innovations
Abstract: Significant progress has been made in nanotechnology in recent years, especially in the creation of sensors with a broad range of uses. Among these, carbon nanotubes (CNTs) are cylindrical structures composed of carbon, with diameters in the nanometer range. CNTs originate from graphite sheets, where the graphite layers resemble a rolled-up, continuous, and robust hexagonal mesh. These hexagons have carbon atoms at their vertices. The fabrication of CNTs typically involves …
Published in International Journal of Photochemistry and Photochemical Research · Vol. 2, Issue 2, 2024 · pp. 24–31 Read article
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Cardiovascular Modeling with Computational and Mathematical Methods
Abstract: The cardiovascular system, a complex network responsible for delivering life-sustaining oxygen and nutrients throughout the body, is a prime target for advanced understanding and improved therapies. Due to the inherent difficulties in directly observing internal physiological processes and the complexities of interactions within the system, computational and mathematical modeling have emerged as powerful tools in cardiovascular research. This article explores the significance of these methods in unveiling the heart's secrets …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 12, Issue 2, 2025 · pp. 11–21 Read article
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Clinical Medicine Done with Clinical Accuracy
Abstract: The advancement of clinical medicine has progressively underscored the significance of accuracy in diagnosis and therapy. This article examines the concept of "Clinical Medicine Administered with Clinical Precision," emphasising how innovations in diagnostics, data analytics, and personalised treatments are transforming the healthcare environment. Clinicians can provide therapy that is not only successful but also personalised to each patient's requirements by combining evidence-based practices with patient-specific factors including genetic profiles, comorbidities, …
Published in Emerging Trends in Personalized Medicines · Vol. 3, Issue 1, 2026 · pp. 6–19 Read article
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Activation Energy in Photochemical and Thermally Driven Reactions: Mechanistic Insights, Kinetic Modelling and Photocatalytic Applications
Abstract: Chemical reactions constitute fundamental processes in which reactants are transformed into products through the breaking and formation of chemical bonds. In photochemical systems, these transformations are initiated or influenced by the absorption of light, making energy transfer mechanisms particularly significant. A key parameter governing reaction kinetics is activation energy, defined as the minimum energy required for reactant molecules to undergo a successful transformation. This article focuses on the role of …
Published in International Journal of Photochemistry and Photochemical Research · Vol. 4, Issue 1, 2026 · pp. 21–26 Read article
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Self Healing Material: An Introduction
Abstract: Self-healing materials have emerged as a transformative innovation for sustainable infrastructure and advanced applications such as wearable electronics and smart transportation systems. These materials possess the intrinsic ability to repair damage autonomously or with minimal external intervention, thereby extending service life and reducing maintenance costs. Inspired by biological systems, self-healing mechanisms are broadly classified into extrinsic approaches, such as microcapsule and vascular networks based healing, and intrinsic mechanisms involving reversible …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 604–611 Read article
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Recent Trends in Heavy Metal Pollution of Groundwater: A Review
Abstract: Heavy metal pollution in groundwater has emerged as a major environmental and public health concern worldwide due to its persistence, toxicity, and potential for bioaccumulation. Rapid industrialisation, urban expansion, intensive agriculture, mining activities, and improper waste disposal have significantly increased the release of heavy metals into subsurface environments. Groundwater, being a primary source of drinking water in many regions, is particularly vulnerable to contamination, posing serious risks to human health …
Published in International Journal of Environmental Noise and Pollution Control · Vol. 4, Issue 1, 2026 · pp. 14–24 Read article
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Phytoremediation of Aquaculture Wastewater: Duckweed (Lemna minor L.) as a Phytoremediator
Abstract: Aquaculture systems discharge huge quantities of waste into the aquatic ecosystem, in the form of excretory products and excess feed. These have grave implications on physicochemical and biological quality of the receiving environment. The study aimed to determine potential of duckweed (Lemna minor L.) for phytoremediation of aquaculture effluent. Hundred grams (100 g) of duckweed was grown in 10 L aquaculture effluent for 7-, 14-, 21-, and 28-day retention period …
Published in International Journal of Pollution: Prevention & Control · Vol. 3, Issue 1, 2025 · pp. 13–19 Read article
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An Immunohistochemical Study to Assess the Role of Myofibroblasts in Diagnosing and Predicting the Outcome of Oral Squamous Cell Carcinoma
Abstract: Background: Squamous cell carcinoma (SCC) accounts for approximately 94% of all oral malignancies, hence establishing oral squamous cell carcinoma (OSCC) as one of the top 10 most prevalent malignant tumors. Cells with several functions, such as macrophages and myofibroblasts, play a vital role in the biological behavior of tumors. This study aimed to assess and evaluate the prevalence of myofibroblasts (MF) and macrophages in SCCs occurring in the oral region. …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 2, Issue 1, 2024 · pp. 13–17 Read article
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Precision Medicine Approaches for Cancer Therapy Recent and Advance
Abstract: Recent advances in biotechnology have made it possible to identify intricate and distinctive biological characteristics linked to carcinogenesis. Proteomic and RNA studies, immunological markers, tumor and cell-free DNA profiling, and other methods are utilized to find these traits in order to optimize anticancer treatment for specific patients. In recent years, the focus of clinical trials has shifted considerably to enhance treatment outcomes in cancer therapy. Rather than being primarily centered …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 14, Issue 1, 2025 · pp. 1–11 Read article
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Photochemical Insights into Light: Responsive Heterocyclic Compounds
Abstract: eterocyclic compounds are significant in a wide range of chemical fields. They are crucial components of the structural makeup of bioactive substances. Such compounds can be conveniently transformed through photochemical processes. Chemical reagents are rarely utilized. It is possible for members of one compound family to change into members of another. There is discussion of three key categories of photochemical rearrangements involving heterocyclic compounds: Photochemical reactions involving hydrogen atom transfer …
Published in International Journal of Photochemistry and Photochemical Research · Vol. 1, Issue 2, 2023 · pp. 01–07 Read article
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Industry 4.0 and Smart Manufacturing: A Review
Abstract: This review looks at Industry 4.0 and smart manufacturing's idea, enabling technologies, implementation issues, and future prospects. Drawing on recent literature, the paper synthesizes key pillars such as the Industrial Internet of Things (IIoT), cyber-physical systems (CPS), artificial intelligence, digital twins, and additive manufacturing. It highlights integration requirements across supply chains, cyber security concerns, workforce implications, and standards activities that influence adoption. The literature survey focuses on empirical studies and …
Published in International Journal of Manufacturing and Production Engineering · Vol. 3, Issue 2, 2025 · pp. 14–17 Read article
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A Study to Assess the Effectiveness of Information Booklet on Knowledge Regarding the Usage of Menstrual Cups and Their Benefits Among Teenage Girls in Selected Pre-University (PU) Colleges, Tumkur
Abstract: Menstruation is a natural and essential biological process experienced by millions of women worldwide every month. However, despite its universality, menstruation continues to be surrounded by social stigma, myths, and inadequate awareness, particularly in low- and middle-income countries like India. The lack of proper menstrual education often leads to fear, embarrassment, and discomfort among adolescent girls as they begin to experience their menstrual cycles. These challenges hinder their ability to …
Published in International Journal of Midwifery Nursing And Practices · Vol. 3, Issue 2, 2025 · pp. 13–29 Read article
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A Review Study of Bio-Psycho-Social Challenges and Interventions for Women During their Perinatal Period
Abstract: Pregnancy causes women to face dynamic and sudden changes in their body and psyche, and sometimes they might as well feel dissociated or separated from the journey. Even though they mentally adapt to the pregnancy, they require constant support at all levels to face the challenges during this crucial period. The goal of the current research is to examine the bio-psycho-social challenges and interventions for women during their perinatal period. …
Published in International Journal of Children · Vol. 1, Issue 2, 2024 · pp. 31–37 Read article
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Persistent Atmospheric and Ecosystem Impacts of Enteric Methane Emissions from Intensive Livestock Production Systems
Abstract: Enteric methane emissions from intensive livestock production systems exert a significant long-lasting influence on atmospheric stability and ecosystem integrity. Recent observations confirm that global methane emissions continued to rise through the early 2020s, with total emissions exceeding 620 teragrams per year by 2024, driven by expanding ruminant production and associated feed systems. Anthropogenic sources accounted for more than 330 teragrams per year, reflecting sustained growth in agricultural and fossil fuel …
Published in International Journal of Atmosphere · Vol. 2, Issue 2, 2025 · pp. 18–38 Read article