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256 articles for “screening”
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Molecular Docking Analysis of Berberis aristata Phytocompounds as Potential Growth Factor Receptor Blockers in Cancer Therapy
Abstract: Middle-aged and older women are susceptible to breast cancer (BC), a potentially fatal condition. When breast cancer is diagnosed, the median age is 62. Breast cancer diagnoses in women under 45 are comparatively uncommon, whereas the bulk of breast cancer diagnoses occur in women 62 and older. Growth factor receptors are interesting therapeutic targets because of their critical role in the pathophysiology of cancer. Vascular endothelial growth factor receptors (VEGFR-2) …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 3, Issue 2, 2025 · pp. 1–10 Read article
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Exploring Oroxylum indicum Phytochemicals as VEGFR-2 Inhibitors: A Molecular Docking Approach for Cancer Management
Abstract: Cancer is still a major health problem around the world and is one of the top causes of death. A protein called VEGFR-2 (vascular endothelial growth factor receptor 2) is important because it helps blood vessels grow by supporting the survival, movement, and growth of certain cells. This process is essential for tumors to grow and spread to other parts of the body. This study focused on evaluating the binding …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 3, Issue 2, 2025 · pp. 48–62 Read article
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Innovations in Targeted Drug Discovery for Personalized Medicine
Abstract: Personalized medicine is revolutionizing modern healthcare by custoizing treatment plans to match an individual’s genetic makeup, protein expression, and metabomlic characteristics. Also referred to as precision medicine, this approach seeks to improve therapeutic outcomes, reduce adverse effects, and make efficient use of healthcare resources. The incorporation of various omics technologies—including genomics, proteomics, transcriptomics, metabolomics, and epigenomics—has greatly advanced our ability to understand disease biology and molecular variations specific to each …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 3, 2025 · pp. 19–41 Read article
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In silico Molecular Docking Analysis of Stephania glabra phytocompounds Targeting Thymidylate Kinase for potential Antituberculosis Activity
Abstract: Tuberculosis (TB) is an infectious disease caused by the bacteria Mycobacterium tuberculosis. It mainly affects the lungs and spreads through the air when a person with active TB in their lungs coughs, sneezes, or spits. This study investigates several bioactive compounds derived from plants to forecast how effective plant-based ligands will be at preventing tuberculosis. The purpose of the study was to use computational techniques to assess the effectiveness of …
Published in International Journal of Molecular Biotechnological Research · Vol. 3, Issue 2, 2025 Read article
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An Expected Cardiovascular Disease Detection Using Deep Learning Techniques
Abstract: Many avoidable deaths globally are caused by CVD, often due to individuals remaining unaware of their risk factors until severe symptoms, such as heart attacks or strokes, appear. This study utilizes retinal images as the dataset to explore the potential of retinal imaging as a non-invasive diagnostic tool for early detection of cardiovascular diseases (CVD). The delay in diagnosis and treatment highlights the need for sophisticated diagnostic instruments that can …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 14, Issue 2, 2024 Read article
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Smart Polymer Composites with Multifunctional Capabilities Integrating Electroactive Polymers Conductive Nanofillers and Flexible Electronics for Advanced Sensing and Actuation Systems
Abstract: Smart polymer composites have gained significant attention to their ability to integrate polymer matrices with conductive nanofillers, offering tunable electrical, mechanical, and electroactive properties. These composites are highly responsive to external stimuli such as electrical fields, mechanical stress, and temperature variations, making them ideal for applications in flexible electronics, soft robotics, and adaptive sensing systems. This research investigates the effect of nanofiller dispersion on the performance of polymer composites, optimizing …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 946–965 Read article
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Synthesis, Molecular Docking and Biological Evaluation of Novel Chlorobenzenesulfonamide Analogues of Ibuprofen as Anti-Bacterial, Anti-Diabetic and Anti-Alzheimer Agents
Abstract: In this work, we have synthesized novel chlorobenzensulfonamide tertiary amide based analogues of Ibuprofen (Ibu) and investigated them for their anti-bacterial, anti-diabetic and anti-Alzheimer activities. In the first step, Ibu was converted to amide derivatives by incorporating different aromatic amines. These were further converted into sulfonamide analogues (Sul-Ibu, 1-9) by treating it with p-chlorobenzensulfonyl chloride. Sul-Ibu (1-9) were screened against S. aureus, B. subtilis, S. mutans, E. coli, P. aeruginosa, …
Published in International Journal of AgroChemistry · Vol. 3, Issue 1, 2025 · pp. 35–49 Read article
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Association between Diabetes Type and Family History of Diabetes: A Cross-Sectional Analysis of Gender Differences and Genetic Influences
Abstract: Introduction: Diabetes mellitus DM is one of the fast-growing chronic metabolic disorder in the world, with high impact and burden in low- and middle-income country. Although genetic predisposition is a central determinant of diabetes risk, particularly for Type 2 diabetes (T2D), the contribution of familial aggregation varies across populations. In many parts of the world where diabetes is rising very fast understanding the relationship between diabetes type and family history …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 3, 2025 · pp. 43–50 Read article
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Targeting Papain-Like Protease of Re-Emerging Coronaviruses
Abstract: Re-emerging Corona viruses (CoVs), including SARS-CoV (S-CoVs), and SARS-CoV-2 (S-CoV-2), continue to pose a global health threat due to their high mutation rates, zoonotic spillover potential, and capacity for immune evasion. The global pandemic of year 2019, caused by S-CoV-2, has highlighted the importance for robust antiviral strategies beyond vaccines and RNA polymerase or main protease inhibitors, which are susceptible to resistance. One promising therapeutic target is the S-CoV-2 papain-like …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 15, Issue 3, 2025 · pp. 46–62 Read article
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RFID Based Smart Trolley Billing System Using IoT
Abstract: Customers experience better retail interactions while operations become more efficient in the modernizing retail industry. Shopping through traditional methods requires lengthy manual scanning for products and billing operations leading retailers to require automation solutions for streamlining these processes. This system consists of RFID detection alongside 8051 microcontroller processing and load cells monitoring and uses IoT communications and relay controls to power an intelligent automated shopping cart. Real-time data tracking functions …
Published in Journal of Semiconductor Devices and Circuits · Vol. 12, Issue 3, 2025 · pp. 1–8 Read article
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AI Approaches in Gait and Posture Analysis: A Review
Abstract: This review synthesizes current research on the application of artificial intelligence (AI) in gait and posture analysis, focusing on methodologies, algorithms, and clinical applications. It examines the use of machine learning (ML) and deep learning (DL) techniques to extract relevant features from sensorderived data, offering objective, and automated assessments that surpass traditional methods. A systematic literature review was conducted, analyzing studies that utilized AI for gait and posture analysis with …
Published in Research and Reviews : Journal of Computational Biology · Vol. 14, Issue 3, 2025 · pp. 1–3 Read article
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Hyper Personalization Using AI: Elevate Fitness
Abstract: In the modern era, many individuals find it challenging to prioritize their health and well-being due to busy lifestyles filled with work, academic, and personal obligations. Conventional fitness and nutrition programs often apply uniform strategies that overlook individual differences in body type, preferences, and goals. This lack of real-time feedback and contextual customization often leads to poor user engagement and unsatisfactory results over time. Elevate is a comprehensive, AI-powered fitness …
Published in Journal of Mobile Computing, Communications & Mobile Networks · Vol. 12, Issue 3, 2025 · pp. 10–21 Read article
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CRISPR-Cas9: Revolutionizing the Genetic Frontier
Abstract: The rapid development of CRISPR/CRISPR-associated enzyme (Cas) technology has enabled truly customised treatment of human genetic disorders, paving the way for recent developments in the field of gene therapy. Because CRISPR/Cas can accurately target and edit individual genes within a genome, it has established itself as a formidable tool for genetic manipulation. CRISPR/Cas9 technology allows for precise editing of specific DNA sequences in an organism's genome. This method uses three …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 3, Issue 2, 2025 Read article
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Exploring Recent Advancements in Nanomedicine for Tumor Microenvironmental Tissue Engineering
Abstract: The combination of tissue engineering and nanomedicine is transforming cancer treatment by offering creative ways to get around problems with conventional therapies. Recent developments in nanomedicine are examined in this review, with an emphasis on how they might be used to comprehend and control the tumor microenvironment (TME), a dynamic and complex environment that has a major impact on the course of cancer and the effectiveness of treatment. Targeted interactions …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 3, 2025 · pp. 122–136 Read article
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Machine Learning Framework for Optimizing Polymer–Metal Oxide Composites as Charge Selective Layers in Perovskite Solar Cells
Abstract: To achieve high-performance and stability of perovskite solar cells (PSCs), it was important to incorporate innovative interfacial materials to tune the balanced charge extraction, low recombination, and enhanced operational lifespan. On this note, polymer composites with metal oxides have been proposed as promising candidates as charge selective layers (CSLs), whereby they present a rare combination of tunable energy levels, improved film forming abilities, and better interface engineering capabilities. In this …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 1073–1098 Read article
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Efficacy and Efficiency of Fingerprint Powder Derived from Natural Flowers – Development and Evaluation of Sustainable Fingerprint Powders
Abstract: Fingerprints are crucial elements in forensic investigations. Latent or invisible fingerprints are commonly recovered from the scene of crime and hence require an attention for which visualization methods are needed. Conventional methods are relatively expensive, which may cause harmful threats and health hazards due to presence of chemical content. This study offers a cheap and sustainable fingerprint powder sourced from natural materials. In this study the powders were prepared from …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 15, Issue 3, 2025 · pp. 6–17 Read article
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An Ultraviolet-Curable Nano Cerium Oxide Coating and Its Anti Ultraviolet /Blue Light Properties
Abstract: An ultraviolet (UV)-curable nano cerium oxide (CeO2) coating with enhanced blue light and UV shielding properties, prepared using an ultrasonic blending method, is presented. This study systematically investigated the optimal synthesis conditions for nano CeO2, as well as the effects of UV intensity and CeO2 concentration on the curing kinetics and blue/UV light shielding performance of the UV-curable nanocomposite. The results indicate that the synthesized nano CeO2 exhibited improved mechanical …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 306–324 Read article
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Flying Drone Using KK Flight Controller
Abstract: This paper presents the design, development, and testing of a quadcopter drone using the KK2.1.5 flight controller, with an emphasis on stability and educational value. The KK2.1.5 controller features are inbuilt LCD screen, inbuilt programming, enabling direct configuration and tuning without the need for a computer interface, which makes it highly suitable for beginners and students. The drone is built using a modular frame architecture, which allows for easy replacement …
Published in International Journal of Advanced Control and System Engineering · Vol. 3, Issue 2, 2025 · pp. 20–25 Read article
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Clinical Trial to Find the (Asbab) Aetiology and (Ilaj) Treatment of (Marz-e-Akyās Khusyat-ur-Rahim) Polycystic Ovarian Syndrome (PCOS)
Abstract: Introduction: Polycystic Ovarian Syndrome (PCOS) is common endocrine disorder. It is clinically defined as the syndrome characterized by amenorrhoea, hirsutism and obesity associated with polycystic ovaries. Diagnosis is made on the Rotterdam criteria, established in 2003. The criteria require the presence of 2 of the following 3 criteria: 1. Oligo-ovulation or an ovulation. 2. Hyperandrogenism. 3. Polycystic ovaries through ultrasound evaluation. Methods: Diagnosed patients were enrolled in the trial into …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 12, Issue 3, 2025 · pp. 30–37 Read article
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AI in Healthcare: Drug Delivery in Tuberculosis
Abstract: Tuberculosis (TB) , mainly caused by Mycobacterium tuberculosis, remains a major global health burden, accounting for millions of new infections and deaths each year. Although progress has been made in diagnosis and treatment, the growing threat of multidrug-resistant (MDR) and extensively drug-resistant (XDR) TB makes disease control increasingly difficult. Conventional diagnostic approaches such as chest X-rays, sputum smear microscopy, and culture methods continue to play an important role, but they …
Published in Trends in Drug Delivery · Vol. 13, Issue 1, 2026 · pp. 9–17 Read article