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333 articles for “in-situ”
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Floating In-Situ Gel for Gastric Retention Delivery
Abstract: When taken orally, medications with a limited window of absorption in the gastrointestinal tract (GIT) are typically accessible to the extremities due to the partial release of the active component and the brief residence period at the absorption site. Because they prolong the duration of the drug's presence in the stomach, they are made with high density and have the capacity to swell. Because oral fluids go more quickly through …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 11, Issue 2, 2024 · pp. 24–32 Read article
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Advances in Polymeric In Situ Drug Delivery and Soft Biosensors: Innovations in Biochemical Sensing and Personalized Healthcare
Abstract: Advanced healthcare and personalized medicine are undergoing a transformation thanks to in situ medication delivery systems and biochemical sensor technology. Polymeric in situ drug delivery systems form gels upon administration, releasing medications in a controlled manner and providing benefits such as ease of administration and enhanced patient compliance. Similarly, advancements in soft electronics, including flexible and stretchable biosensors, enable continuous, in situ biochemical monitoring, conforming to complex biological environments like …
Published in International Journal of Cheminformatics · Vol. 2, Issue 1, 2024 · pp. 27–32 Read article
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pH-Triggered In-Situ Nasal Gel Systems for Migraine Therapy: A Review
Abstract: Intranasal drug delivery has gained considerable attention as a non-invasive route for delivering drugs to both systemic circulation and the central nervous system, particularly for the treatment of migraine. Traditional nasal formulations such as sprays and drops often show poor therapeutic performance due to rapid mucociliary clearance and limited retention within the nasal cavity. To overcome these challenges, in-situ gel systems have been designed, which transform from a liquid to …
Published in Trends in Drug Delivery · Vol. 13, Issue 2, 2026 Read article
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Multi-Response Optimization of Turning Parameters with Vikor-Entropy Method on Machining of AA6061-TiB2 In-Situ Composites
Abstract: In the manufacturing and metal cutting industries, the quality of the surface and strength is essential in defining the surface finish; an excellent surface finish indicates excellent quality in the product. The influence of machining parameters speed, feed and depth of cut on responses like material removal rate, surface roughness and Power consumption on turning of AA6061-TiB2 composites is investigated using the VIKOR-ENTROPY method. The effects of changing parameters on …
Published in Journal of Polymer & Composites · Vol. 11, Issue 8, 2023 · pp. 256–268 Read article
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Influence of Tib2 Wt. % on the Microstructural and Mechanical Properties of In-Situ Processed Stir-Cast Metal Matrix Composite of Al-6061
Abstract: Currently, there is an increasing trend in the automotive and aerospace industries towards the adoption of lighter and stronger materials to reduce weight and enhance fuel efficiency. Metal matrix composites must be developed in order to increase the overall performance of automobiles and aircraft as a result of this transition. Among the various composite materials employed, Aluminium Matrix Composites (AMCs) are frequently utilised to meet stringent industrial requirements. The purpose …
Published in Journal of Polymer & Composites · Vol. 13, Issue 1, 2025 · pp. 655–661 Read article
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Development of Novel Materials with Photocatalytic Effect
Abstract: For capturing solar energy and for converting it into electric power, it is utmost essential to design materials that can be used for this purpose. Generally, the materials deployed for converting solar energy into electric energy are sensitive to UV-radiation. If the material used for this purpose are sensitive to visible light, it will be the breakthrough research. It has been a challenge to design materials with novelty of being …
Published in International Journal of Photochemistry and Photochemical Research · Vol. 1, Issue 2, 2023 · pp. 25–39 Read article
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Assessment of Heavy Metals in Underground Water Situated at Automobile Workshops in Ede Metropolis
Abstract: The study investigated the determination of heavy metals concentration (Co, Cd, Ni, Pb, and Cr) in underground water situated in auto-mobile workshops in Ede metropolis. Four different samples were collected, two from the auto-mobiles workshop while two were collected 50 meters away from the Auto-mobiles workshop in both local governments which served as control. The result was Cr-0.416– 0.477 mg/L; Cd-0.018–0.040 mg/L; Pb-0.038–0.066 mg/L; Ni-0.042–0.052 mg/L; Co-0.043–0.200 mg/L. Cobalt has …
Published in Research & Reviews : Journal of Statistics Read article
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Revolutionizing Gastro-retentive Drug Delivery: Exploring Innovative Formulation Strategies and Mechanisms in Floating in Situ Gel Raft Forming System
Abstract: An in-depth exploration of the transformative shift underway in gastro-retentive drug delivery, spotlighting the utilization of Floating Drug Delivery Systems (FDDS) and specifically honing in on the innovative formulation strategies and mechanisms inherent in Floating In Situ Gel Raft Forming Systems. FDDS present a promising avenue for revolutionizing drug delivery efficacy by capitalizing on buoyancy to float atop the gastric fluid surface, thereby extending gastric residence time and improving drug …
Published in Trends in Drug Delivery · Vol. 11, Issue 1, 2024 · pp. 9–21 Read article
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Role of Satellite Data Assimilation on ERA-Interim and ERA5 Wave Parameter Ratios – A Case Study based on Year-long In-Situ Observations in the Bay of Bengal
Abstract: The rapid decline in the energy resources forced mankind to tap other forms of natural energy resources in the light of exponential increase in the demand due to over-population. The energy from ocean waves is one of the cleanest sources of energy available perennially that changes seasonally and is site-specific. To assess the wave power potential at any site, knowledge of the wave parameters such as wave height, period and …
Published in Journal of Remote Sensing & GIS · Vol. 16, Issue 1, 2025 · pp. 1–20 Read article
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In-Situ Polymerized GO/PANI Composites: Structural Evolution, Optical Modulation, and NH₃ Sensing at Room Temperature
Abstract: Graphene oxide (GO)/polyaniline (PANI) composites with varying PANI contents (20, 40, and 60 wt%) were synthesized via in-situ oxidative polymerization and systematically investigated for their structural, morphological, optical, and gas-sensing properties. X-ray diffraction (XRD) confirmed a progressive increase in interlayer spacing and partial exfoliation of GO layers with increasing PANI content, indicating intercalation-assisted hybridization. Fourier transform infrared (FTIR) spectroscopy revealed the characteristic vibrational bands of both constituents and confirmed strong …
Published in Journal of Polymer & Composites · Vol. 14, Issue 4, 2026 Read article
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A Quasi-experimental Research Endeavor to Evaluatethe Impact of a Structured Instructional Program on Adults' Comprehension of Disaster Awareness and Management in Chosen Villages Situated in Moga,Punjab
Abstract: A quasi-experimental research was conducted to evaluate the efficiency of a structured instructional program on adults' comprehension of disasters and their management. The study involved a sample of 60 adults, divided equally into an experimental group of 30 and a control group of 30. The knowledge score of adults in experimental group regarding disaster and its management among adults was average (54%) and below average (46%) before imparting the structured …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 1, Issue 1, 2023 · pp. 25–31 Read article
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In Situ Investigation of Hemidesmus indicus Phytocompound Extracts as a Therapeutic Target for Acute Myeloid Leukemia
Abstract: Objective: Acute myeloid leukemia (AML) is an apoptotic condition in the hematopoietic system induced by the differentiation and maturation of stem cells into erythrocytes, and leukemic cell proliferation is suppressed as the PI3K-Akt-mTOR pathway is pharmacologically targeted with certain inhibitors. As a result, in silico molecular docking of compounds against AML receptors, CTMP, was used in computational research on Hemidesmus indicus to uncover therapeutic phytochemicals for AML. Thus, this study …
Published in Research and Reviews : Journal of Computational Biology · Vol. 13, Issue 1, 2024 · pp. 38–53 Read article
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Seasonal Variation in the Weibull Parameters from In Situ Measurements and Model: A Case Study in the Bay of Bengal
Abstract: Seasonal variation of wind speed (U10) and its distribution are essential for the design of wind energy converters (WEC). In this study, year-round wind speed observations from a deepwater moored buoy at a location in the Bay of Bengal are used to assess the potential for wind power generation and are used to validate the ERA5 model. Model-U10 distribution is confined to low wind speeds with high occurrence in the …
Published in Journal of Alternate Energy Sources & Technologies · Vol. 15, Issue 1, 2024 · pp. 30–40 Read article
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Sacred Resilience: The Intersection of Religious Beliefs and Psychological Well-being in Crisis Situation
Abstract: Background: The relationship between religious beliefs and psychological well-being has been a focal point of psychological research, particularly in the context of crises. Understanding how religious beliefs contribute to psychological resilience may enhance support mechanisms for individuals facing crises. Objective: This study aims to examine the intersection of religious beliefs and psychological resilience during crises, focusing on how faith-based practices influence coping strategies and overall mental health outcomes. Importance: This …
Published in International Journal of Behavioral Sciences · Vol. 2, Issue 1, 2025 · pp. 16–21 Read article
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Estimation and Study of Contamination by Elements (Ni, Cu, Mg, Sn) in Dust of Areas near Fuel Stations in Najaf Governorate
Abstract: The research focused on studying and determining the levels of pollution in dust collected from various stations in the city of Najaf near fuel situations represented by four Fuel Situations (Soor Alnajaf Situation, Reebal Situation, Alkarar Situation, Alqudus Situation ), for this we selected 4 situations for current study, to determine the levels of pollution and compare them with the internationally permitted levels of elements (nickel, copper, and magnesium). Air …
Published in International Journal of Pollution: Prevention & Control · Vol. 3, Issue 2, 2025 · pp. 6–14 Read article
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Autonomous Drones for Search and Rescue Opera-tions: State of the Art and Future Prospects
Abstract: Autonomous drones have significantly transformed search and rescue (SAR) operations by improving the speed, precision, and overall effectiveness with which rescuers are able to locate and provide assistance to individuals in need. By leveraging state-of-the-art technologies such as computer vision, artificial intelligence (AI), machine learning, and advanced navigation systems, drones have proven invaluable in carrying out complex rescue missions. These technologies enable drones to navigate hazardous environments autonomously, even in …
Published in International Journal on Drones · Vol. 1, Issue 2, 2025 · pp. 9–13 Read article
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Stress Level and Coping Strategies Among the Students Preparing for Common Entrance Test in Coaching Classes of a Selected City
Abstract: Stress is a natural response of your body to any type of demand, whether it is a positive or negative experience. When individuals experience stress due to external factors, their bodies release chemicals into the bloodstream, which can be beneficial if the stress is caused by physical danger. However, if the stress is a result of an emotional situation and there is no way to channel this additional energy and …
Published in International Journal of Emergency and Trauma Nursing and Practices · Vol. 1, Issue 1, 2023 · pp. 13–21 Read article
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ML-Driven Defect Detection in Additive Manufacturing of Polymer Composites Using Thermal Imaging
Abstract: Polymer-based flexible biosensors have emerged as a pivotal technology in continuous health monitoring, yet their deployment in real-world settings is often hindered by undetected micro-defects and signal distortion caused during fabrication or usage. Existing diagnostic frameworks typically rely on post-hoc processing or bulky instrumentation, failing to offer scalable, real-time detection during additive manufacturing workflows. This study introduces an end-to-end, thermographic imaging-integrated framework for in-situ defect identification during the additive manufacturing …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 201–215 Read article
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Formulation Challenges in Long-acting Injectable Small Molecules: Emerging Strategies and Perspectives
Abstract: Long-acting injectable (LAI) formulations represent a transformative approach in pharmacotherapy, particularly for conditions demanding sustained drug exposure over weeks to months. Although biologics have dominated this space historically, the adaptation of LAI technology to small molecules presents a distinct and complex set of challenges rooted in physicochemical properties, manufacturing scalability, and regulatory expectations. This review systematically addresses the principal formulation barriers encountered in developing LAI small-molecule products, including aqueous solubility …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 13, Issue 2, 2026 Read article
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Chemical Treatment Methods for Types of Chemical and Environmental Pollution: Review
Abstract: Developed countries have witnessed the industrial revolution and technological advancements, as a result, environmental pollution is steadily increasing, negatively impacting living organisms and life sources. The causes are well known, as are the solutions, but major industrialized nations are procrastinating and postponing implementation of solutions because it reduces their profits. To address chemical pollution: reducing the use of nuclear energy, disposing of chemical waste in proper ways, and focusing on …
Published in Journal of Water Resource Engineering and Management · Vol. 12, Issue 2, 2025 · pp. 53–60 Read article