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38 articles for “cell lines”
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Comparative Proteomics: From Cell Lines to Clinical Samples
Abstract: Comparative proteomics is a powerful tool for understanding the molecular differences between various biological samples. It entails identifying and measuring proteins in complex biological samples to assess their abundance, modifications, and interactions under various conditions. This approach plays a crucial role in advancing biomedical research, especially in disease understanding, biomarker discovery, and therapeutic development. While cell lines are widely used for proteomic studies due to their controlled environments and reproducibility, …
Published in Research and Reviews : Journal of Computational Biology · Vol. 13, Issue 3, 2024 · pp. 30–34 Read article
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Iota carrageenan, a Sustainable polymer transformed into a nanogel formulation, by using environment friendly method for antitumor action
Abstract: In the pharmaceutical field, the utilization of polymers, both in their natural form and through chemical modifications, holds immense importance. In this context, a novel and eco-friendly method for the synthesis of nano carrageenan-based polymers has been developed. The efficacy of carrageenan in this domain is attributed to its crosslinking and biological properties, which are largely influenced by its sulfate ion content. This study aims to formulate nanogels via a …
Published in Journal of Polymer & Composites · Vol. 13, Issue 1, 2025 · pp. 881–889 Read article
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Practical studies in Vero cell and Human amnion cells for viral and stem cell applications
Abstract: Vero cells are one of the most popular mammalian continuous cells in molecular, cellular, and microbiological research. African green monkey kidneys are used to make these.One continuous cell line is the Vero cell line. This cell line is dependent on anchorage. Vero cells can be cultured in suspension because they are anchorage independent. Thought to be non-tumorigenic cells that came from a female Chlorocebus sabaeus Numerous viruses can infect vero …
Published in International Journal of Vaccines · Vol. 2, Issue 1, 2025 · pp. 1–8 Read article
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Evaluation of Antioxidant and Cytotoxic activities of Mycelia Biomass and Culture broth of three Edible Mushrooms, Morchella conica, Hericium erinaceus and Pleurotus florida Grown in Submerged Culture
Abstract: Mycelia biomass of three edible mushrooms namely, Morchella conica, Pleurotus florida and Hericium erinaceus were grown as submerged culture in potato dextrose broth supplemented with yeast extract, potassium dihydrogen orthophosphate and magnesium sulphate. The mycelia biomass was extracted with 70% ethanol and culture broth with ethyl acetate. The solvents were evaporated to dryness at low temperature using a rotary vacuum evaporator and the residues thus obtained were used for the …
Published in International Journal of Fungi · Vol. 1, Issue 1, 2024 · pp. 37–50 Read article
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Integration of Modular Multilevel Converter Topology in the Design and Control of Hybrid Electric Vehicles
Abstract: A back-to-back modular multilevel converter (BMMC) based plug-in hybrid electric vehicle power conversion system is proposed to solve the problems of traditional MMC-EV. The local AC harmonics generated by the operation of MMC-EV accelerate the battery degradation and reduce the battery life. Currently, electric vehicles are in great demand due to the rising oil prices and environmental pollution concerns. Since the backbone of electric vehicles is the energy storage system, …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 1195–1205 Read article
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Pharmaceutical Excipient from Agriculture Waste Product
Abstract: Agriculture produces a large Amount of waste, which contain a high amount of cellulose line polysaccharide that form a large part of the plant solid cell wall. This waste product can be use efficiently by a variety of recycling method such as energy source, source of large compound such as cellulose, gum polymers etc. disposal of waste from fruit bearing industry has been problem due to the high cost travel …
Published in Research and Reviews: A Journal of Toxicology Read article
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Drug Screening Using Stem Cell Technology
Abstract: Stem cell technology in drug screening has transformed the research and development sector of pharmaceuticals. Although stem cells imitate their human counterparts in terms of both safety and potential, it is a new paradigm for mimicking diseases of humans and scale measuring for toxicity. These tissues will, therefore, be more predictive of what will happen in humans during clinical situations, compared to conventional cell lines or animal models, since they …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 3, 2025 · pp. 42–51 Read article
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Study Review: Molecular Mechanisms of Nanoparticle-Cell Interaction – Implications for Drug Delivery and Toxicity
Abstract: The application of nanoparticles in drug delivery and biomedical therapies holds great promise, yet their interaction with cells and the underlying molecular mechanisms remains areas of active research. This study explores the molecular mechanisms of nanoparticle-cell interactions, focusing on the effects of gold nanoparticles (AuNPs) and silica nanoparticles (SiNPs) in human cancer cell lines (HeLa and MCF-7). The study examines how nanoparticles are internalized by cells, their impact on cellular …
Published in Research and Reviews: A Journal of Toxicology · Vol. 15, Issue 2, 2025 · pp. 31–40 Read article
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Preparing Chitosan Hybrid Nanocomposites by Novel Additives for Wound Healing
Abstract: Biomaterials made from chitosan have been discovered to be particularly unique marine polysaccharides (or polycarbohydrates) with a wide range of physico-chemical and biological characteristics suitable for biomedicine field. Due to net positive charge of chitosan, it is essentially capable of chemically binding with negatively charged surfaces A biodegradable blend of chitosan nanoparticles (CHT), poly vinyl alcohol (PVA) and polyethylene glycol (PEG) hybridized with metal oxides nanopowders were prepared and used …
Published in Journal of Polymer & Composites · Vol. 11, Issue 2, 2023 · pp. 9–23 Read article
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The Clinical Landscape of Wogonin: Advancing Targeted Treatments for Chronic Diseases
Abstract: The traditional Chinese medicinal herb Scutellaria baicalensis Georgi, commonly known as Chinese skullcap or Huang-Qin, has long been used to treat a variety of conditions, including cancer, viral infections, and seizures. Its pharmacological effects are largely attributed to the high concentration of flavones, particularly wogonoside, and its aglycone derivative, wogonin. Among the bioactive compounds found in S. baicalensis, wogonin has garnered the most scientific attention due to its potent therapeutic …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 12, Issue 1, 2025 · pp. 46–52 Read article
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Preparation, Categorization and Anticancer Study of Novel Bicyclic Compounds from Various Types for (Five and Six)- Membered Ring
Abstract: The characteristics of ring systems change in the presence of functional groups, but in some cases, elements that are considered functional groups can be classified within the same ring. Compounds that contain only carbon and hydrogen are called homogeneous rings, while those that contain other elements are called heterogeneous rings. The atom substituted in place of the carbon atom is referred to as a heteroatom. Generally, the heterocyclic atom is …
Published in Journal of Catalyst & Catalysis · Vol. 12, Issue 3, 2025 · pp. 18–30 Read article
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Phytochemical Screening and Biological Activity of Pomegranate Extracts
Abstract: Pomegranates are renowned for their abundance of bioactive compounds that exhibit potent antioxidant, anti-inflammatory, and antimicrobial properties, making them a subject of growing interest in natural medicine. This study aimed to compare the biological activities of ethanolic extracts derived from different parts of the pomegranate plant—specifically, the bark, peel, and leaves. A comprehensive investigation was conducted to evaluate their phytochemical composition and assess their antimicrobial, antioxidant, and anticancer properties. The …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 12, Issue 2, 2025 · pp. 64–79 Read article
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Comprehensive Review of Kojic Acid and Its Derivatives: Biological Activities, Safety, and Therapeutic Potential in Depigmentation
Abstract: There are several uses for kojic acid in human medicine, particularly in depigmentation. Additionally, derivatives of it are suggested to enhance efficacy, avoid side effects, and stop chemical degradation. With an eye toward human use and an attempt to clarify the action mechanisms, the goal of this study was to review the most recent scientific literature regarding the biological activities and safety information of kojic acid or its derivatives. During …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 16, Issue 2, 2025 · pp. 45–53 Read article
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Drive Line for Plug-in Electric Vehicle with PMSM Motor and Hydrogen Fuel Cell
Abstract: In the era of transportation, the best effort will be to replace conventional fossil fuels. Instead, the usage of fossil fuels will give way to renewable energy sources and other clean energies. Many institutions promote the developments and research in the area of hydrogen fuel cell development. This paper passes through the hydrogen fuel cell area as the primary source considered here is a hydrogen fuel cell. Since electric motors …
Published in Journal of Nuclear Engineering & Technology · Vol. 14, Issue 1, 2024 · pp. 32–49 Read article
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Comparison of a Human Papillomavirus Test with the Hybrid Capture 2 and a Real-Time PCR Method for 18 High-Risk and Low-Risk Human Papillomavirus Infections in Women
Abstract: Squamous intraepithelial lesions (SILs), which are a kind of cancer, and HUMAN papillomavirus (HPV) viral load have frequently been investigated as a risk factor in findings that were in dispute. These studies made use of several HPV viral quantitation assays [including the commercially available hybrid capture 2 (HC2) assays], which vary in their capacity to consider variations in cervical cell collection, linear dynamic range of viral load quantitation, and identified …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 15, Issue 1, 2025 · pp. 10–16 Read article
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Towards Finding the Impact of Kinetic Information on Short Term Memory based Task
Abstract: The main objective of this report is to discover whether haptic data have an effect on the retention of a directive to choose a place scattered on a 2D plane. The necessity for a feasible workshop for the cell manufacturing line in plant assembly led to the idea. We created an organized viscuo-haptic training model that covered a grown-up arm’s workstation and used three different Ways to change the extent …
Published in Journal of Control & Instrumentation · Vol. 14, Issue 1, 2023 · pp. 1–8 Read article
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An Evaluative Comparison of CD123 and CD66c as Biomarkers to Detect Minimal Residual Disease in B-Cell Acute Lymphoblastic Leukemia
Abstract: Background: B-cell Acute Lymphoblastic Leukemia (B-ALL) often shows lineage heterogeneity with lymphoid cells expressing myeloid markers. Minimal Residual Disease (MRD) refers to the small number of cancer cells that may remain in a patient's body after treatment and that are undetectable by standard diagnostic methods. In diseases like B-cell Acute Lymphoblastic Leukemia (B-ALL), MRD is a critical prognostic indicator, as its presence can signal a higher risk of relapse. In …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 3, 2024 · pp. 7–12 Read article
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Study of Multiple Modules Solar System Electricity Generation
Abstract: Solar energy is a sustainable, non-depleting, and ecologically safe energy source that originates from sunlight. Every hour, the globe receives enough solar energy to meet its energy demands for a whole year. In the current world, we need power on a regular basis. This solar energy is used in commercial, residential, and industrial settings. It readily absorbs energy from direct sunlight. In this post, we looked at solar energy from …
Published in Journal of Power Electronics and Power Systems · Vol. 16, Issue 1, 2026 · pp. 25–32 Read article
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Factors Affecting Shear Stress on Tablet Hardness and Disintegration
Abstract: The quality and effectiveness of pharmaceutical tablets depend heavily on several factors influencing shear stress on tablet hardness and disintegration. These factors include formulation composition, wherein the selection and concentration of excipients and active ingredients affect how the tablet material responds to shear stress. Additionally, the compression force, speed, and duration during tablet compression are critical, impacting tablet hardness and disintegration properties. Tablet geometry and design, along with tablet press …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 15, Issue 2, 2024 · pp. 1–19 Read article
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A Review Paper on Lean Manufacturing Implementation Techniques
Abstract: Lean manufacturing was initially designed to reduce waste and maximise resource usage. Later, lean wasdeveloped in response to the competitive and ever-changing business environment. Organizations are compelled to deal with difficulties and complications because of the business environment's rapid change. The ability of any business, whether manufacturing- or service-focused, to consistently and methodically adapt to these changes in order to increase the value of its products may ultimately determine whether …
Published in Recent Trends in Fluid Mechanics · Vol. 11, Issue 2, 2024 · pp. 1–9 Read article