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40 articles for “NF”
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Molecular Pharmacokinetics and Structural Docking of Phenolic Acids for Targeting NF-κB Pathway Components in Inflammation and Fibrosis: A Computational Approach Toward Therapeutic Discovery
Abstract: Inflammation and Fibrosis are critical pathological processes associated with various chronic diseases, often mediated by the nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) signaling pathway. This study investigates the therapeutic potential of phenolic acids as modulators of the NF-κB pathway, aiming to identify novel ligands that can effectively interact with key components of this signaling cascade. A comprehensive computational approach was employed, utilizing molecular docking, pharmacological screening, and post-docking …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 3, Issue 1, 2025 · pp. 14–31 Read article
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Botanical Blockade: Phytochemical Targeting Of Nf-Κb in Cancer Therapy
Abstract: The control of inflammation, corpuscle survival, proliferation, and allowed response are all influenced by the acute archetypal agent NF-κB. Its abnormal activity is typically seen in a range of malignancies, where it aids in bump advancement, metastasis, and treatment waste. The function of NF-κB in scar analysis is discussed in this product, along with significant phytochemicals that seem to be interested in targeting this pathway, based on recent investigation. It …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 12, Issue 1, 2025 · pp. 13–21 Read article
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Molecular Docking of Nigella Sativa Phytocompound as Inhibitors of Transcription Factors NF-KB Implicated in Rheumatoid Arthritis
Abstract: Objectives: Nigella sativa, a plant considered around the world as the most treasured nutrient-rich herb for centuries together in different civilizations, is exceptionally known for its high levels of antioxidant properties. Free radical intensification due to oxidative stress plays a key role in the pathogenesis of rheumatoid arthritis by activating the NF-KB protein that regulates the expression of the genes involved in inflammation. Methods: This study involves in-silico approach to …
Published in International Journal of Molecular Biotechnological Research · Vol. 2, Issue 2, 2024 · pp. 42–55 Read article
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Characterization and Performance of a Multiphase Lignocellulosic-Polymeric Composite Growth Media in an IoT-Automated NFT Hydroponic System
Abstract: Hydroponics utilizing the Nutrient Film Technique (NFT) entails a type of soilless agriculture involving the delivery of a continuously flowing and thin film of nutrient-filled solution onto the roots of plants. With the move toward sustainable and efficient urban agriculture in the contemporary world and need to produce more effective and resource-efficient solutions, there have been significant efforts aimed at improving these techniques through advanced materials and automation. A consistent …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 542–555 Read article
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Mobile-Friendly Libraries: Leveraging QR and NFC for Instant Access to Digital and Physical Resources
Abstract: Mobile technology has drastically altered the way that users access and interact with information. Therefore, it is paramount for libraries to consider innovative solutions for improving accessibility and efficiency. This paper focuses on the application of QR (Quick Response) codes and NFC (Near Field Communication) technologies in libraries to grant instant access to both digital and physical resources. Libraries can use QR and NFC codes to create frictionless user interactions …
Published in Journal of Advancements in Library Sciences · Vol. 12, Issue 2, 2025 · pp. 77–82 Read article
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Vitamin D Mitigates Inflammation and Downregulates Importin α3 in Non-Alcoholic Fatty Liver Disease (NAFLD)
Abstract: Background: Pro-inflammatory cytokines, such as TNF-α, IL-1β, IL-6, and IL-8, seem to play a crucial role in the progression of NAFLD as they activate the transcription factor NF-кB. The activated NF-кBp50/RelA subunits are translocated to the nucleus by Importin α3 and Importin α4. Numerous studies have indicated a negative association between NAFLD and vitamin D levels. Low vitamin D levels have been correlated with histological severity, necro-inflammation, and fibrosis in …
Published in International Journal of Cheminformatics · Vol. 4, Issue 1, 2026 · pp. 1–16 Read article
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Precision Medicine for Neurofibromatosis Type 1: Progress and Prospects in Drug Discovery
Abstract: Objective: The development of neurofibromas, café-au-lait spots, and other neurological problems are the hallmarks of neurofibromatosis type 1 (NF1), a hereditary disorder. The dearth of efficacious pharmaceutical therapies underscores the need for novel therapeutic approaches, even in the face of clinical variability. Through very accurate prediction of the binding affinity of possible therapeutic drugs with the target protein, the computational technique known as “molecular docking” has become a potent tool …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 2, Issue 1, 2024 · pp. 01–15 Read article
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Comprehensive Evaluation of Quercetin from Bauhinia purpurea for Its Anti-Acne and Anti-Inflammatory Potential, Including Advances in Quercetin-Loaded Nanogel Formulation
Abstract: Acne vulgaris is among the most prevalent chronic inflammatory dermatoses in clinical dermatology, afflicting a substantial proportion of the global adolescent and adult population. Conventional pharmacotherapies — including topical retinoids, benzoyl peroxide, and systemic antibiotics — remain the therapeutic mainstay; however, their long-term utility is progressively undermined by adverse cutaneous reactions, systemic toxicity, and the rising prevalence of antibiotic-resistant Cutibacterium acnes strains. These limitations have intensified scientific interest in plant-derived …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 13, Issue 2, 2026 Read article
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Turmeric as a Key Ingredient in Cosmeceuticals: New Scientific Evidence
Abstract: Turmeric (Curcuma longa), particularly its active compound curcumin, is gaining recognition in cosmetics and medicine for its therapeutic properties. Its antioxidant, anti-inflammatory, and antimicrobial effects make it a popular skincare ingredient, helping reduce inflammation, brighten skin, and fight aging. In addition to treating dandruff and promoting hair growth, Turmeric is also good for scalp health. Curcumin increases the body's antioxidant defenses. Inhibits inflammation and anti-oxidants. Curcumin, a powerful compound found …
Published in International Journal of Toxins and Toxics · Vol. 2, Issue 1, 2025 · pp. 28–36 Read article
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Quality Appraisal for the Ornamental Bird, Fish, Dog, and Cat Foods Available in Bangladesh
Abstract: The study aimed to assess if the chemical composition of different avian, aquatic, dog, and cat foods commonly available in Chattogram, Bangladesh adheres to the recommended standards. Food samples were collected and subjected to proximate analysis for the dry matter (DM), crude protein (CP), crude fibre (CF), ether extract (EE), nitrogen free extract (NFE), and total ash (TA). The plant seeds used for ornamental birds exhibited substantial variability in terms …
Published in Research and Reviews : Journal of Veterinary Science and Technology Read article
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Evaluating Water Savings in Vertical and Horizontal Hydroponic Systems Using Nutrient Film Technique
Abstract: A study conducted at SVCAET, IGKV, Raipur, focuses on water conservation in hydroponics using the nutrient film technique (NFT). The research evaluated both vertical and horizontal hydroponic systems. Initially, plants were grown in a nursery before being transplanted into either the vertical or horizontal system. In these systems, nutrient-rich water was continuously circulated over the plant roots. The study assessed water usage and the remaining water in the system on …
Published in International Journal of Nutritions · Vol. 2, Issue 1, 2025 · pp. 1–8 Read article
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Virtual Reality Based Decentralized Educational Art Gallery
Abstract: One can experience the forefront of education by engaging with our virtual reality (VR) powered decentralized educational art gallery. This groundbreaking platform seamlessly integrates VR technology with decentralized networks, crafting an unmatched learning journey. Curated collections of art from diverse cultures and eras can be explored, accompanied by interactive educational modules that deepen one’s understanding of each piece. One can engage with fellow learners in real time, fostering collaboration and …
Published in Journal of Multimedia Technology & Recent Advancements · Vol. 11, Issue 2, 2024 · pp. 31–37 Read article
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Vitamin D Mitigates Inflammation and Downregulates Importin α3 in Non-Alcoholic Fatty Liver Disease (NAFLD)
Abstract: Non-alcoholic fatty liver disease (NAFLD) affects about one-third of the population in the United States and Western countries, reaching up to 90% among obese individuals and those undergoing bariatric surgery. Characterized by hepatic fat accumulation, NAFLD progresses from simple steatosis to non-alcoholic steatohepatitis (NASH), fibrosis, and, in rare cases, hepatocellular carcinoma. Linked intricately with metabolic syndrome, including diabetes and obesity, NAFLD development involves insulin resistance and hyperinsulinemia. Experimental evidence consistently …
Published in International Journal of Cheminformatics · Vol. 4, Issue 1, 2026 Read article
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Kinds of Digital Payment Technology: Exploring the Evaluation
Abstract: Digital payment technologies has revolutionized financial transactions, immolating faster, safe, and more approachable solutions. This paper inspects the evolution and types of digital payment systems, embrace Near Field Communication (NFC), Quick Response (QR) codes, mobile wallets, blockchain-based payments, and biometric authentication. It examines key drivers of adoption, such as accessible and technological advancements, while addressing threats like security risks and regulatory compliance. The study provides the role of these technologies …
Published in Journal of Telecommunication, Switching Systems and Networks · Vol. 12, Issue 1, 2025 · pp. 9–14 Read article
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Comparison Analysis of Transformer Boosting and Induced Degeneration Topology Design of LNA for Millimeter Wave Frequency Range Using Polymeric Substrates
Abstract: In this study, a comparison between transformer boosting and source degeneration LNA topologies is conducted using two polymeric substrates—Polyimide (PI) and Liquid Crystal Polymer (LCP)—for millimeter-wave (mmWave) applications. With growing interest in flexible and high-frequency electronics, polymeric materials offer unique advantages such as low dielectric constants, mechanical flexibility, and thermal stability. The analysis explores gain, return loss, and noise figure performance while evaluating the influence of dielectric properties on the …
Published in International Journal of Electrical and Communication Engineering Technology · Vol. 3, Issue 2, 2025 · pp. 1–24 Read article
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Comprehensive Review of Adenoid Cystic Carcinoma: Pathogenesis, Diagnosis, and Emerging Therapeutic Approaches
Abstract: Adenoid cystic carcinoma (ACC)is an infrequent neoplasm, highly malignant, that develops mainly in the salivary glands with the potential to exist in any secretory glandular sites, including the lacrimal glands, breast, and respiratory tract. ACC usually has a benign initial course, but conversely, it is notoriously aggressive in behavior with high incidence of perineural invasion, local recurrence, and distant metastasis, mostly to the lungs. The tumor’s molecular features are characterized …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 14, Issue 3, 2025 · pp. 1–17 Read article
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Effect of hybridization on mechanical Characteristics of hemp,bamboo and jute reinforced epoxy bio composites
Abstract: In the present study, hemp, jute and bamboo fibres have been reinforced with epoxy resin to develop several bio-composites (hemp/epoxy, jute/epoxy, bamboo/epoxy, hemp/jute/epoxy, hemp, bamboo, epoxy and hemp/jute/bamboo/epoxy). Their mechanical characteristics (impact strength, flexural strength, and tensile strength) have been evaluated by conducting standardized ASTM tests on the fabricated bio-composite specimens. Among these, the hybrid epoxy composite reinforced with hemp, jute, and bamboo fibers has exhibited superior tensile and impact …
Published in Journal of Polymer & Composites · Vol. 12, Issue 3, 2024 · pp. 81–91 Read article
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Enhancement of Mechanical Properties in Hemp Fiber-Reinforced Epoxy Composites Using Graphene Nanoplatelets
Abstract: This study investigates how incorporating graphene nanoplatelets (GNPs) influences the mechanical performance of hemp fiber–reinforced epoxy composites. Hemp fibers were chemically treated by alkali treatment to improve fiber–matrix adhesion owing to their high specific strength, stiffness, renewability, and environmental friendliness. Graphene nanoplatelets were dispersed in acetone by probe sonication and added to acetone epoxy matrix at a concentration of 0.5 wt% and 1.0 wt%, respectively. Composite laminates were prepared by …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 98–109 Read article
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Double slope Solar Still by using Nano Embedded Binary Eutectic PCM: A Review
Abstract: Solar distillation is an economical and eco-friendly technique. Concerns about the increasing need for clean drinking water for home and commercial uses are spreading around the world. In rural and tiny settlements with limited access to water and electricity, solar water distillation is a viable method for removing salty water from drinking water. The efficiency and performance of thermal energy storage materials based on phase change materials (PCM) and nanofluids …
Published in Trends in Mechanical Engineering & Technology · Vol. 14, Issue 1, 2024 · pp. 29–33 Read article
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Exploring the Botanical and Pharmacological Significance of Aristolochia rotunda Linn (Zarawand Mudahraj): Traditional Uses, Habitat, and Bioactive Potential
Abstract: The plant Aristolochia rotunada Linn (Zarawand Mudahraj) is a member of the Aristolochiaceae family. Its rhizomes are the most valuable portion utilised in the pharmaceutical industry, mostly because of their abundance in bioactive compounds. The medicinal plant Aristolochia rotunda Linn exhibits a spectrum of pharmacological activities essential for combating hyper-uricaemia-induced inflammation. Its anti-inflammatory effects are mediated by inhibiting TNF-α, IL-1β, IL-8, and NF-κB p65 protein expression, crucial in synovial tissue. …
Published in Research & Reviews : Journal of Herbal Science · Vol. 13, Issue 2, 2024 · pp. 33–39 Read article