Search
227 articles for “Bioactive”
-
Comparative Assessment of Antibacterial Effectiveness, Bioactivity, Fluoride Release, and Microleakage of Various Bioactive Smart Composites: An In Vitro Investigation.
Abstract: The demand for dental composites with enhanced properties has led to the development of bioactive smart composites aimed at addressing multiple aspects of restorative dentistry. This in vitro investigation aimed to conduct a comparative assessment of the antibacterial effectiveness, bioactivity, fluoride release, and microleakage properties of various bioactive smart composites. Bioactive smart composites are emerging dental materials designed to promote remineralization and inhibit bacterial growth, thereby enhancing the longevity of …
Published in Journal of Polymer & Composites · Vol. 12, Issue 3, 2024 · pp. 76–86 Read article
-
Evaluation of Mucoadhesive Polymers for Nasal Delivery of Herbal Bioactives
Abstract: A study assessed mucoadhesive polymers for intranasal herbal bioactive administration with higher residence time and mucosal permeability. Chitosan, Carbopol® 934P, and HPMC K15M were utilized to manufacture mucoadhesive nasal gels with standardized herbal bioactive fractions. Formulations were examined for pH, viscosity, spreadability, drug content, mucoadhesive strength, in-vitro release, ex-vivo penetration, and short-term stability. All formulations demonstrated a suitable pH for nasal usage and uniform drug content (97.48 ± 1.12% to …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 1680–1689 Read article
-
Comparative Analysis of Bioactive Phytochemical Profiles of Moringa Oleifera and Aegle Marmelos Grown in Bundelkhand
Abstract: A comparative analysis of the bioactive phytochemical profiles of Moringa oleifera and Aegle marmelos grown in the Bundelkhand region was conducted to explore their potential health benefits. These properties make healing plants valuable in herbal medicine, supporting various aspects of health and well-being. The study aimed to determine the differences in the concentrations of bioactive compounds such as phenolic, flavonoids, alkaloids, and vitamins C and E in the leaves and …
Published in Emerging Trends in Metabolites · Vol. 1, Issue 2, 2024 · pp. 14–24 Read article
-
Fungal-derived Nutraceuticals & Bioactive Compounds with Physiotherapeutic and Health- promoting Properties: A Comprehensive Review
Abstract: Fungal-derived nutraceuticals represent a rapidly expanding field in biomedical research, offering a rich source of bioactive compounds with diverse therapeutic applications. This comprehensive review examines the physiotherapeutic and health-promoting properties of fungal metabolites, including polysaccharides, terpenes, proteins, peptides, alkaloids, fatty acids, vitamins, and minerals. Fungi produce over 9,000 bioactive compounds from approximately 22,500 microbial metabolites, with less than 5% of the fungal kingdom explored [1] . The major bioactive constituents …
Published in International Journal of Fungi · Vol. 2, Issue 2, 2025 Read article
-
Forage Bioactive Compounds and Rumen Microbiota: Exploring Colonization, Density, and Diversity Dynamics in Dairy Cows
Abstract: The rumen microbiota plays a pivotal role in the health, productivity, and sustainability of dairy cows, with forage serving as a fundamental dietary component influencing microbial dynamics. This review explores the intricate interactions between forage bioactive compounds – such as tannins, saponins, alkaloids, and flavonoids – and the rumen microbiota, focusing on their effects on colonization, microbial density, and diversity. Forage bioactives modulate microbial adhesion, biofilm formation, and growth patterns, …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 15, Issue 3, 2025 · pp. 15–26 Read article
-
Interaction of Bioactive Component of Aframomum melegueta on Molecular Docking
Abstract: Computational mimicry of the structure of large complexes created by di- and poly-interaction of molecules has been termed molecular docking. The purpose of molecular docking is the prediction of the three-dimensional structures of interest, this is due to that docking only produces plausible candidate structures. The docking was carried out between the bioactive compounds against 5α-reductase, 3β-hydroxy-steroid dehydrogenase, and 17β-hydroxy-steroid dehydrogenase of returned binding energy, BE (kcal/mol) between -5.9 and …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 2, Issue 1, 2024 · pp. 51–60 Read article
-
A Retrospective Analysis of Resin-Based Polymer Composites and Bioactive Glass-Polymer Hybrids Regarding Secondary Caries and Durability
Abstract: Aim- To compare the 2-year clinical survival and failure modes of a Resin-Based Polymer Composites and BioactiveGlass-Polymer Hybrids in Class I and II posterior restorations. Methods-A total of 550 restorations were placed in adult patients across various private dental practices in India to ensure a diverse clinical demographic. Teeth were randomly assigned and restored with either a hybrid composite (Te-Econom, IvoclarVivadent; n=275) or a Resin-Modified Glass Ionomer Cement (GC Gold …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 1089–1095 Read article
-
Catalyst: Free Synthesis of Bioactive Molecules via Green Chemical Principles
Abstract: This study explores the catalyst-free synthesis of bioactive molecules, emphasizing the application of green chemical principles. Traditional synthetic methods often rely on hazardous reagents, solvents, and metal catalysts, which can pose significant environmental and health risks. In contrast, the catalyst-free approach leverages benign reaction conditions, such as solvent-free systems, ambient temperature, and pressure, to achieve efficient and selective transformations. We present a comprehensive investigation into various bioactive molecule syntheses, including …
Published in Journal of Catalyst & Catalysis · Vol. 11, Issue 1, 2024 · pp. 17–21 Read article
-
Qualitative and Quantitative Effects of Non-Thermal Atmospheric Pressure Plasma and ErCr: YSGG Laser Activation on Surface Remineralization and Fluoride Release of Three Different Fluoride Varnishes
Abstract: Dental caries remains a prevalent oral health concern worldwide, prompting ongoing research into innovative approaches for caries prevention and management. This experimental investigation endeavors to conduct a comparative assessment of the bioactivity, fluoride release kinetics, shear bond strength, and compressive strength of glass ionomer cement (GIC) augmented with three distinct types of inorganic bioactive nanoparticles. Bioactive nanoparticles have garnered interest in dental materials for their potential to enhance material properties …
Published in Journal of Polymer & Composites · Vol. 12, Issue 5, 2024 · pp. 292–303 Read article
-
Optimization Of Solar Drying Parameters for Turmeric and Papaya Leaves: Effects on Nutritional and Bioactive Compound Retention
Abstract: This study focuses on the optimization of solar drying parameters for turmeric and papaya leaves, based on their impact on retention of nutritional and bioactive compounds. One of the most crucial postharvest procedures is solar drying as it decreases the moisture content in plant materials, thereby increasing shelf life and preserving quality. This study considers traditional methods as open sun drying (OSD) and advanced solar dry techniques, including Hybrid Indirect …
Published in International Journal of Electrical Power and Machine Systems · Vol. 3, Issue 1, 2025 · pp. 29–37 Read article
-
Comparative Study of Bioactive Phytochemicals from Hexane Extract of Two Amaranthaceae Leafy Vegetables by GC-MS Method
Abstract: Amaranthus tricolor Linn and Amaranthus viridis Linn, belonging to the Amaranthaceae family, are popularly consumed leafy vegetables in India and many other countries globally. The bioactive components of Hexane extract from these two plants have been analysed using gas chromatography-mass spectrometry (GC–MS) technique. According to analysis, both species contain a total of nineteen important chemicals. Of these, ten were found in A. tricolour L. and nine in A. viridis L. …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 7–17 Read article
-
Polymeric Micelles for Medicinal Plant Solubilization and Delivery of Bioactive Compounds
Abstract: This study involved the design, fabrication, and characterization of polymeric micellar nanocomposites utilizing amphiphilic block copolymers to effectively encapsulate and transport hydrophobic phytoconstituents. The selected bioactive molecule is curcumin, a polyphenol with limited water solubility. A polymeric system known as PEG-PCL was utilized to fabricate core-shell nanostructures by a solvent evaporation-induced self-assembly method. The resulting nanocomposites exhibited homogeneity and colloidal stability, characterized by a zeta potential of −18.7 ± 1.4 …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 208–219 Read article
-
Evaluation and Fabrication of 3D Printed Bioactive β-TCP/PCL Scaffolds for Bone Tissue Engineering
Abstract: Bone is one of the tissue types that is transplanted the most worldwide. Each year, there are over four million procedures that incorporate the use of bone grafts or substitutes to help heal bone deficiencies. These treatments are still limited greatly, and there is always a demand to help because of trauma, cancer, infection, and arthritis. Because of this, researchers are targeting improvement in developing bioactive three-dimensional (3D) scaffolds that …
Published in Journal of Polymer & Composites · Vol. 14, Issue 4, 2026 Read article
-
Generative Design of Bioactive Orthopedic Composites for Fracture Repair Using an Integrated Conditional GAN–Transformer Framework: A Multi-Objective Approach
Abstract: Orthopedic composite implants for fracture repair must simultaneously satisfy conflicting mechanical and biological demands: high fracture toughness, sufficient compressive stiffness, and bioactive surface chemistry enabling osteoblast adhesion and mineralization. Existing design approaches rely on trial-and-error experimentation, yielding sub-optimal trade-offs between these objectives. This paper presents an integrated conditional Generative Adversarial Network–Transformer (cGAN-T) framework for fully computational, multi-objective generative design of hydroxyapatite (HA)-reinforced polymer composite microstructures targeting Orthopedic fracture repair. A …
Published in Journal of Polymer & Composites · Vol. 14, Issue 4, 2026 · pp. 21–35 Read article
-
Aquaculture Advancements Through Bioactive Molecules
Abstract: A wide range of seafood species – including fish, shellfish, squid, and bivalves – generate by-products that are often discarded as waste. However, these by-products hold great potential for developing innovative functional food products. Because there is limited opportunity to recycle natural resources, the loss of profit may be accompanied by the loss of ecological sustainability, given that the “wastes” of industrial processing can account for up to 75% of …
Published in International Journal of Marine Life · Vol. 2, Issue 2, 2025 Read article
-
Plant Bioactive Metabolites and Their Role in the Prevention and Control of Dental Diseases and Infections.
Abstract: The oral diseases, including dental caries and periodontitis, affect masses worldwide, and have historically been managed with synthetic antimicrobials that cause deleterious side effects, leading to mounting bacterial resistance. Consequently, contemporary dentistry is rapidly shifting toward phytomedicine using plant bioactive molecules, such as polyphenols, terpenes, anthraquinones (berberin, eugenol, curcumin, catechins, allicin, and azadirachtin. These compounds offer potent antimicrobial, anti-inflammatory, and tissue-regenerative properties that are crucial for preventing and curing dental …
Published in Emerging Trends in Metabolites · Vol. 3, Issue 1, 2026 · pp. 47–66 Read article
-
Bioactive Compounds in Ethanolic Extract of Strychnos innocua Root Using Gas Chromatography and Mass Spectrometry (GC-MS)
Abstract: Medicinal plants are of great relevance with endless pharmaceutical and therapeutic properties. They are source of wide array of secondary metabolites or bioactive compounds/phytochemicals (phenols, alkaloids, flavonoids, terpenoids, tannins, steroids and saponins) which can discharge numerous biological functions (antimicrobial, antioxidant, antiviral, antifungal, anti-fibrotic, immune-modulatory, cytotoxic, antipyretic, antitumor, antihelminthic, antiprotozoal, antibacterial, and so on). The use of gas chromatography and mass spectrometry analysis in identifying the bioactive compounds in the ethanolic …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 1, Issue 1, 2023 · pp. 9–14 Read article
-
Unlocking The Bioactivity Potential: Molecular Insights and Predictions of Salen, Salophen, Allicin, Curcumin, and Piperine
Abstract: In this work, the prediction of the biological activity of several significant molecules, including salen, salophen, allicin, curcumin, and piperine, are discussed. Using Molinspiration software, the molecular properties of these compounds were calculated. These molecules are highly significant due to their extensive potential in medical applications. Salen and salophen, for instance, play crucial roles in cancer chemotherapy and act as inhibitors of angiogenesis. Curcumin is renowned for its antioxidant properties, …
Published in International Journal of Cheminformatics · Vol. 1, Issue 2, 2023 · pp. 14–21 Read article
-
Exploring the Bioactive Potential of Himalayan Lichens: Phytochemical and Antimicrobial Profiling of Xanthoparmelia tinctina and Pyxine subcinerea Extracts
Abstract: The symbiotic association that develops between cyanobacteria, algae, and fungi results in the composite organism known as lichens, which has traits similar to those of plants but differs in its separate parent organisms. Lichens can have a variety of morphological characteristics, including foliose structures that resemble flat leaves, crustose structures that resemble flake crystals, fruticose branches that have short, leafless branches, and leprose-powder-like appearances. Due to their therapeutic potential, lichens …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 14, Issue 2, 2024 · pp. 21–28 Read article
-
Rauwolfia Serpentina: A Comprehensive Phytochemical Study of Its Bioactive Metabolites
Abstract: Rauwolfia Serpentina is an important medicinal plant used in Ayurveda, Unani, and folk medicine system of medicine. This plant grew as a bush in company of other plants as an evergreen structure. It is commonly known as ‘Sarpaghanda’. in Ayurvedic and Unani medicine system. It is safe and effective for the treatment of snakebites and various types of disease like malaria, breast cancer, prostate cancer, high blood pressure, insomnia, epilepsy, …
Published in Emerging Trends in Metabolites · Vol. 1, Issue 2, 2024 · pp. 25–50 Read article