All articles
78 articles
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Stiff Person Syndrome: Advances in Understanding, Diagnosis, and Treatment of a Rare Autoimmune Disorder
Abstract: Stiff Person Syndrome (SPS) is a rare and complex autoimmune neurological disorder characterized by progressive muscle stiffness, rigidity, and painful spasms. This chapter provides a comprehensive overview of SPS, exploring its pathophysiology, clinical presentation, diagnostic challenges, and current treatment approaches. We discuss the latest research findings, including the role of autoantibodies, genetic factors, and environmental triggers in the development of SPS. The chapter examines various diagnostic methods, emphasizing the importance …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 3, 2024 · pp. 35–43 Read article
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A Prospective Observational Study of Prescription and Quality of Life: Gastroesophageal Reflux Disease in Territory Care Hospital
Abstract: Aims and objective: The main aim of the study is to know the quality of life in GERD patients and the management of GERD with the help of prescription patterns and patient counseling. Methodology: After receiving approval from Departmental Research Committee AIPBS with the reference no AIPBS/2021/4586/11 on dated 30 September 2021 and also approved from the Ethics Committee of Biomedical and Health Research, Adesh University with the reference no …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 3, 2024 · pp. 14–21 Read article
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A Research Study on Navigating Medication Risks Through MFRS (Medication Fall Risk Score and Evaluation Tool) and DART (Drug Associated Risk Tool) Among Patients with Polypharmacy
Abstract: Background information: The advancements in medical science continue, but the safety of medication usage is still a question mark and has become a crucial area for researchers to focus on. In the need of the above, various scoring systems and tools have been developed in pharmacy practice research. Prior to the present work, we did a systematic review and meta-analysis and identified two such tools: the medication fall risk score …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 3, 2024 · pp. 1–13 Read article
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Current Perspectives of Prader -Willi Syndrome: A Multisystem Approach
Abstract: Prader-Willi syndrome (PWS) is a genetic disorder with multisystem involvement, caused by the lack of expression of genes on the paternally inherited chromosome 15q11.2-q13 region from paternal 15q11-q13 deletions (about 60%) or maternal uniparental disomy 15 or both. It is a complex and contiguous gene disorder which affects the multiple systems with many clinical presentations especially hypothalamic insufficiency. The clinical features are characterized by short stature position, developmental delay, cognitive …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 2, 2024 · pp. 42–48 Read article
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Assessment of dietary sources, eating habits, and lifestyle among Pharmacy students in India
Abstract: Aim and Objective: Balanced Diet and their sources play a vital role in maintaining physical, mental and health, especially in college students and in teenagers. Knowledge regarding the dietary source, and eating habits of Pharmacy students is important as health care professionals play critical and central role in management and in accessing the quality of health care population. The purpose of this survey study is assessment of dietary sources, eating …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 2, 2024 · pp. 49–55 Read article
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Impact of Various Front-line Hypertensive medication on Blood Pressure Control During Maximum Exercise Testing in Coronary Artery Disease Patients
Abstract: It has long been known that blood pressure (BP) and cardiovascular morbidity are related. It is acknowledged that blood pressure during activity may serve as a more reliable indicator than resting blood pressure, which might not accurately reflect blood pressure at other times. Goals: 1) To assess how blood pressure behaves during physical activity in individuals with coronary artery disease (CAD) whose hypertension is managed with first-line antihypertensive medications. 2) …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 2, 2024 · pp. 37–41 Read article
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Prevalence and Distribution of Staphylococcus Aureus in Clinical Samples Across Age Groups
Abstract: The bacteria that cause everything from ordinary skin infections to serious illnesses is called Staphylococcus aureus. It is now known that Staphylococcus aureus may develop resistance to a variety of drugs. Staphylococcus aureus has been displaying an unusual kind of resistance to antibiotics, especially to those based on β-lactum. As a result, Methicillin Resistant Staphylococcus Aureus (MRSA) is the new name for the resistant strain of Staphylococcus aureus. The prevalence …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 2, 2024 · pp. 15–19 Read article
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Knowledge About the Noscomial Infection, Their Control and Prevention Procedures Followed at Matrisadan Complex UPHC 04 Rajpur-Sonarpur Municipality, Kolkata, West Bengal
Abstract: In this research work, a detailed study about Nosocomial infection has been done. Different Nosocomial infections have been discussed and a detailed study about prevention of Nosocomial infection has been done in one of the government healthcare facilities, named as UPHC 4 Rathtola Matrisadan, Rajpur-Sonarpur Municipality, Kolkata-700150. The study aims to highlight effective prevention strategies and measures implemented at this facility to control the spread of infections within the healthcare …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 2, 2024 · pp. 27–36 Read article
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Meta-Analysis on Antibiotic Resistance and Its Irrational Use in India: Need of Antibiotic Stewardship Program Implementation
Abstract: Antibiotic resistance is a major health issue in developing countries. This issue is increasing exponentially due to increased consumption, easy availability of medicine and higher incidence of inappropriate use. Moreover, India stands as one among the highest infectious disease burdened country in the world. This study aims to conduct a statistical analysis to find the association between antibiotic resistance and its irrational use in India. Thereby, emphasizing the need for …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 2, 2024 · pp. 6–14 Read article
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Digital Health Interventions in Cardiovascular Pharmacology: A Review
Abstract: Cardiovascular diseases (CVDs) represent a formidable global health challenge, demanding innovative strategies for timely detection, effective management, and continuous monitoring. This study delves into the transformative potential of digital health interventions (DHIs), such as telemedicine and remote monitoring, in reshaping cardiovascular care paradigms. DHIs offer unparalleled accessibility, convenience, and personalized attention, thereby promising to revolutionize traditional approaches to cardiovascular health management. One of the foremost advantages of DHIs lies in …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 2, 2024 · pp. 1–5 Read article
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Practical approach for Type 2 Diabetes: Role of DPP4 Inhibitors
Abstract: Dipeptidyl peptidase-4 inhibitors (DPP-4Is) have become essential in managing type 2 diabetes mellitus (T2DM) due to their ability to enhance incretin hormone activity, which promotes insulin secretion and inhibits glucagon release. These agents effectively lower HbA1c levels by 0.5–1.0%, are weight-neutral, and have a low risk of hypoglycemia, making them suitable for a broad patient population, including the elderly. The antidiabetic market in India is vast. Gliptin as group row …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 2, 2024 · pp. 20–26 Read article
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Investigation of Migraine
Abstract: Individual's medical history, and any potential side effects that may occur. It is also important to consult with a healthcare provider before beginning any new treatment plan, as they can provide guidance on the best course of action based on the individual's specific needs and circumstances. In addition to medication, individuals with migraines can explore various treatment avenues. Lifestyle modifications, such as incorporating regular exercise, maintaining a healthy diet, managing …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 1, 2024 · pp. 38–45 Read article
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Impact and Outcomes of Alkaline Water Therapy (Supportive Therapy) in Management of Diabetes, Hypertension and Thyroid Disorders: An Evidence-based Research Study.
Abstract: The present study is a retrospective observational cohort study involving the usage of alkaline water as supportive therapy in the management of metabolic disorders. Patients were randomly selected on daily basis reviewed and followed up. Sixteen patients in the yelahanka Bangalore region who tested positive for diabetes mellitus, hypertension and thyroid disorders and were willing to participate were included in the study. Patients who weren't willing to participate or who …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 1, 2024 · pp. 32–37 Read article
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Evaluation Of Anti Obesity Activity Of Citrus Sinensis & Citrus Limon By High Fat Diet Induced Model Using Danio Rerio
Abstract: Obesity, defined by the World Health Organization (WHO) as an abnormal or excessive fat accumulation that may impair health, is becoming one of the greatest challenges to global health in this millennium, with more than 300 million men and nearly 450 million women obese globally in 2018. Obesity turns into serious problem globally. Zebrafish model can be used extensively for drug screening due to its low maintenance cost, comparatively short …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 1, 2024 · pp. 24–31 Read article
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Antioxidant activity of Passiflora foetida leaf extracts and silver nanoparticles in diabetic induced rats
Abstract: The anti-oxidant system present in our body prevents against the free radicals. Anti-oxidants were glutathione peroxidise,serum catalase,vitamin E, ascorbic acid and superoxide. In our study the plant extract of Passiflora foetidae were used to estimate the antioxidant levels in diet-induced diabetic rats. The mean of glutathione peroxide of normal rats was 92.98±1.65. "The mean of diet-induced diabetic rats was 152.50 ± 1.92*. Diabetic rats treated with sitagliptin and vildagliptin had …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 1, 2024 · pp. 10–16 Read article
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Effects of Gypsophila on Airway Inflammation in Guinea pig model of ovalbumin‐induced Asthma
Abstract: To look at how Gypsophlia (GSP) affects airway inflammation in a model of ovalbumin-induced asthma in guinea pigs (OVA).Methods: Using a random number table, sixty healthy female guinea pigs were split into six groups, each consisting of ten rats: the normal control, OVA, and GSP (0.45, 0.9, 1.8, and 3.6 g/kg). The ovalbumin and lipopolysaccharide sensitization approach was used to create the OVA guinea pig model. The GSP groups received …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 1, 2024 · pp. 17–23 Read article
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A Review on Evolution of Medicine After and During Corona
Abstract: As of the beginning of 2023, 6.7 million people had perished from COVID-19, according to the World Health Organization. However, there have also been some positive developments, such as the notable decline in influenza-related deaths in the first year of the pandemic as a result of masking and social isolation, as well as the quick adoption of vaccines utilizing cutting-edge technologies like mRNA vaccines, which hold out great promise for …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 1, 2024 · pp. 1–9 Read article
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A Review Article on Clinical Pharmacy Overview
Abstract: Clinical pharmacy is the branch of pharmacy and is the practice that helps the pharmacist provide services to promote rational and economical drug therapy that it’s appropriate, safe and cost effective which successively optimizes the utilization of medication and promote wellness, health and disease prevention. The reason for emergency of clinical pharmacy practice has been remarkably consistent worldwide. Clinical pharmacist provide care for patients altogether health care setting, clinical pharmacist …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 11, Issue 2, 2023 · pp. 06–12 Read article