Research and Reviews: A Journal of Pharmaceutical Science
Volume 10, Issue 1 (2019)
Published
Table of contents
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A Potential Role of Ayurvedic Treatment in Tuberculosis
Abstract: According to the World Health Organization (WHO), tuberculosis (TB) is one of the top tencauses of death worldwide and verified as a global health problem. The main reason of globalhealth problem is generally the tremendous burden of disease. In the estimated survey of TB in2016, 10.4 million people suffered with TB and 1.7 million died with this disease. After a longperiod of neglect some new interventions are developed by various …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 10, Issue 1, 2019 · pp. 1–10 Read article
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Design and Evaluation of Promethazine Hydrochloride Rapimelts
Abstract: Objective: In the present study, efforts were taken to develop rapimelts of promethazine HCl—an antiemetic agent with an objective to achieve rapid disintegration, and further improve thebioavailability of drug.Methods:Rapimelts were prepared by direct compression methodusing superdisintegrants such as crospovidone (cp), croscarmellose sodium (ccs), sodiumstarch glycolate (ssg). The prepared formulations were evaluated for precompressionparameters such as bulk density, tapped density, Carr’s compressibility, Hausner ratio andangle of repose. The prepared batches of …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 10, Issue 1, 2019 · pp. 11–19 Read article
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Swine Flu is a Dangerous Pandemic Disease Worldwide: A Review
Abstract: Swine flu is a pandemic disease which is characterised by fever, sore throat, cough, chills,body aches, fatigue, and sometimes diarrhoea, vomiting, running nose, watering eyes, throatpain, and myalgia. It is caused by orthomyxovirus virus subtype (H1N1). Three majorinfluenza viruses (Influenza A, B and C) are identified. Among these viruses, Influenza A isresponsible for causing swine flu. It was first reported in Mexico, which slowly get invaded tonearby countries. The disease …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 10, Issue 1, 2019 · pp. 20–27 Read article
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Development and Characterization of Ion-Activated Ocular in situ Gel of Carbinoxamine Maleate
Abstract: AbstractObjective: To formulate and evaluate ion activated in-situ gel of carbinoxamine maleate by hot method. Methods: Ion activated in-situ gel of carbinoxamine maleate were prepared by hot method. Optimization of carbinoxamine maleate in situ gel was performed using design expert software. Formulation and characterization of optimized batch of in situ gel were performed. Results: The pH of the formulation was found to be satisfactory. The drug content was within acceptable …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 10, Issue 1, 2019 · pp. 28–35 Read article
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Long Acting Depot Formulation: History, Mechanism, its Manufacturing and Market Review
Abstract: Patient compliance is a very important factor in the treatment of any disease. Specially intreatment of chronic diseases such as cancer, arthritis, psychosis patient need to take medicinefor longer time. In such cases long-acting depot injection became excellent option for treatment.This drug delivery involves drug release over a period of several weeks and months. These depotformulations can be prepared by using biodegradable polymer Poly (lactide-co-glycolide)PLGA. Various methods are widely used …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 10, Issue 1, 2019 · pp. 36–46 Read article