Research & Reviews: A Journal of Drug Formulation, Development and Production
Volume 5, Issue 3 (2018)
Published
Table of contents
-
Determination of RP-HPLC Method for Safinamide: Its Bulk and Tablet Dosage Form
Abstract: A new method was established for estimation of Safinamide by RP-HPLC method. The chromatographic conditions were successfully developed for the separation of Safinamide by using Agilent C18 column (4.6×150 mm, 5 µ); flow rate was 1 ml/min, mobile phase ratio was Methnol, Acetonitril (60:40), pH 3 (pH was adjusted with orthophosphoric acid), detection wavelength was 235 nm. The instrument used was WATERS HPLC Auto Sampler, Separation module 2695, photo diode …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 5, Issue 3, 2018 · pp. 1–6 Read article
-
Synthesis and Chemical Characterization of Benzopyran Derivatives Fused to Pyrimidine Moiety
Abstract: In an attempt to find a new class of antimicrobial agents, a series of fused benzopyran derivatives containing pyrimidine moiety were prepared via the reaction of 2-(1h-benzo[d] imidazol-2-yl acetonitrile with 2-amino-3-(1h-benzo[d] imidazol-2-yl)-4-phenyl-4h-chromen-7-ol in the presence of piperidine and anhydrous zinc chloride. The target molecules were also synthesized using interchange component strategy. These compounds were screened for their antibacterial activity against gram-positive bacteria (Staphylococcus aureus and Streptococcus pyogenes), gram-negative bacteria (Pseudomonas …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 5, Issue 3, 2018 · pp. 11–23 Read article
-
Synthesis and Chemical Characterization of Novel Series of Heterocyclic Compounds Containing Nitrogen and Oxygen
Abstract: The aim of this study is to synthesize some novel pyrazoline derivatives and to study their antibacterial activity. As estimated, pyrazoline derivatives exhibited significant to moderate antimicrobial activity. There is no such obsession as completely safe drug. Drugs are prevailing tool, which modify physiological processes for the enhanced or for the worse. A society, which desires to take advantage from them, it will not accomplish all the benefits open to …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 5, Issue 3, 2018 · pp. 24–40 Read article
-
Synthesis and Chemical Characterization of Novel Series of Benzoxazinone Derivatives
Abstract: The objective of the current work is to synthesize some novel benzoxazinone derivatives and to study their antibacterial activity in particular. Thus an effort has been made in this direction. The antimicrobial activity of the synthesized some novel benzoxazinone derivative is summarized.As estimated, benzoxazinone derivatives exhibited significant to moderate antimicrobial activity. Therefore, a detailed study of toxicity is necessary. Heterocycles formed the sites of reactions in many enzymes or co-enzymes. …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 5, Issue 3, 2018 · pp. 41–57 Read article
-
SSK Plus of Sanjeevi Pharma, One Stop Solution for Pseudo-Hunger in Diabetes Mellitus
Abstract: The anti-diabetic effect of SSK Plus tablet of Sanjeevi Pharma was studied in line with modern scientific parameters such as inhibition of alpha-amylase and alpha-glucosidase by in vitro. The individual herbal ingredients of SSK Plus have shown great activity and together have proven to be superior over individual herbs. The study has more than proving the efficacy of Sanjeevi SSK Plus, shows the greatness of Siddha System of Medicine which …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 5, Issue 3, 2018 · pp. 7–10 Read article