Anaphylaxis
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Anaphylaxis: Pathophysiology, Risk Factors, and Clinical Management
Abstract: Anaphylaxis is a syndrome characterized by broncho-constriction, vasodilatation, and hypovolemia, potentially fatal exposure to known or unknown antigens. It can be an immune-mediated (IgE & non-IgE) disease. Immunoglobulin G (IgG), complement related (C3a/C5a), bradykinin, leukotrienes, prostaglandin E2, and ligands of certain G-protein coupled receptors (GPCR) can directly activate mast cells, basophils, eosinophils, neutrophils, endothelial cells and smooth muscles. Serum tryptase level during episodes of anaphylaxis, skin test, and basophil activation …
Published in Research and Reviews : A Journal of Immunology · Vol. 15, Issue 2, 2025 · pp. 1–11 Read article
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Adr Caused Byanti-Snake Venom a Case Report Highlighting the Pathophysiology, Prevention, and It’s Management
Abstract: Even in situations where it wasn't necessary, antivenom research was applied to snake bite cases. In order to improve their level of understanding, primary practitioners should receive training on handling envenomation situations as well as current recommendations and references. In cases of snake bites, antivenom must be delivered according to applicable systemic and original indications.More than ten percent of cases with admitted ASV experience some sort of reaction, ranging from …
Published in International Journal of Toxins and Toxics · Vol. 1, Issue 2, 2024 · pp. 40–46 Read article