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79 articles for “steroids”
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In silico Analysis of nsSNPs in the Human ACTN4 Gene associated with a Steroid-Resistant Nephrotic Syndrome
Abstract: The main motive of this study is to discover nsSNPs of ACTN4 gene through various insilico views. ACTN4 is one of the proteins that play a leading role in cellular pathways by altering cytoskeletal behaviour associated with steroid-resistant nephrotic syndrome. Data of ACTN4 was collected from NCBI dbSNP and Uniport KB and further used to explore adverse outcome using SIFT, PolyPhen, PROVEAN and SNAP2.Out of 11 nsSNPs selected in this …
Published in Research and Reviews: A Journal of Health Professions · Vol. 8, Issue 3, 2018 · pp. 43s–52s Read article
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Muscle vs. Heart: A Comprehensive Review of Anabolic Steroid-Induced Cardiovascular Risks
Abstract: Anabolic-androgenic steroids (AAS) are widely used by athletes and bodybuilders to enhance muscle mass and performance. However, their misuse is associated with serious and often underrecognized cardiovascular risks. Despite their popularity, particularly among young adults, the long-term consequences of AAS abuse on cardiovascular health remain insufficiently explored in the literature. This review aims to: 1. Analyze the cardiovascular implications of AAS use. 2. Elucidate the molecular and physiological mechanisms contributing …
Published in International Journal of Toxins and Toxics · Vol. 3, Issue 2, 2026 Read article
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The Effects of Steroids on One’s Health
Abstract: The widespread use of steroids for both medicinal and non-medical purposes is a significant issue in contemporary culture. This article examines the considerable impact of steroids on human health, focusing on the therapeutic benefits and the adverse side effects associated with their consumption. In the treatment of conditions, such as inflammation, autoimmune disorders, and hormone imbalances, steroids, are frequently prescribed, providing significant relief from symptoms. However, the abuse of these …
Published in Research and Reviews: A Journal of Toxicology · Vol. 16, Issue 1, 2026 · pp. 47–63 Read article
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Assessing the Impact of Topical Steroids on Tinea Infections: An Epidemiological Investigation
Abstract: This retrospective epidemiological study investigates the prevalence and characteristics of modified tinea infections resulting from the use of topical steroids. Analyzing patient records from October 2022 at ‘District General Hospital, Amravati, the study reveals a significant association between topical steroid use and altered clinical features in 89% of cases. Factors such as steroid potency, duration of use, and specific tinea subtypes affected contribute to understanding the epidemiology of modified tinea …
Published in International Journal of Vaccines · Vol. 1, Issue 1, 2024 · pp. 10–18 Read article
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Studies on the Self-Assembly of Steroids and DNA Mediated by Naphthalene-Based Amphiphilic Block Copolymer
Abstract: Amphiphilic block copolymers have attracted considerable interest in pharmaceutical and biomedical applications, including controlled drug release, gene delivery, and biomolecular sensing. In this study, fluorescent amphiphilic block copolymers were designed to facilitate interactions with biological molecules, such as DNA and antiviral agents, enabling their behavior to be monitored through fluorescence spectroscopy. Two novel block copolymers, poly(methyl methacrylate)-b-poly(dimethylaminoethyl methacrylate-co-naphthyl methacrylate) [PMMA-b-P(DMAEMA-co-NMA)] and poly(styrene)-b-poly(tert-butyl acrylate-co-naphthyl methacrylate) [PS-b-P(t-BA-co-NMA)], were synthesized successfully via atom …
Published in Journal of Polymer & Composites · Vol. 14, Issue 5, 2026 · pp. 183–196 Read article
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Management of Steroid Induced Diabetes with Unani Medicine: A Case Report
Abstract: Background: Glucocorticoids (GC), such as prednisolone, are commonly used for their anti-inflammatory and immunosuppressive properties. However, chronic GC use can lead to adverse effects, including diabetes. This case study evaluates the efficacy of Arq Afsanteen, an Unani compound drug, in managing GC-induced diabetes. A 50-year-old man with a family history of type 2 diabetes and a history of partial gastrectomy was diagnosed with sarcoid tuberculosis and began treatment with ATT …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 11, Issue 3, 2024 · pp. 49–53 Read article
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Pharmacological Comparison of Turmeric and Non-Steroidal Anti-Inflammatory Drugs in Pain Relief
Abstract: Pain is one of the most frequently encountered clinical symptoms affecting millions globally and is typically treated pharmacologically with nonsteroidal anti-inflammatory drugs (NSAIDs). However, long-term use of NSAIDs is associated with adverse effects such as gastrointestinal, renal, and cardiovascular issues. In recent years, turmeric and its main active compound, curcumin, have received considerable attention for their reported anti-inflammatory, analgesic, and antioxidant properties as natural therapeutic options. This review seeks to …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 13, Issue 1, 2026 · pp. 19–28 Read article
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Interaction of Bioactive Component of Aframomum melegueta on Molecular Docking
Abstract: Computational mimicry of the structure of large complexes created by di- and poly-interaction of molecules has been termed molecular docking. The purpose of molecular docking is the prediction of the three-dimensional structures of interest, this is due to that docking only produces plausible candidate structures. The docking was carried out between the bioactive compounds against 5α-reductase, 3β-hydroxy-steroid dehydrogenase, and 17β-hydroxy-steroid dehydrogenase of returned binding energy, BE (kcal/mol) between -5.9 and …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 2, Issue 1, 2024 · pp. 51–60 Read article
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Comparative Pharmacognostical and Analytical Evaluation of Desmodium gangeticum (Linn.) and Pseudarthria viscida (Linn.) Wight & Arn. as a Substitute
Abstract: Shalaparni [Desmodium gangeticum (Linn)] is one among the Dashamoola and Pseudarthria viscida (Linn) is used as a substitute instead of Shalaparni in south India especially Kerala state. Macroscopic, microscopic and organoleptic results of the standard drug D. gangeticum (Linn.) and trail drug P. viscida (Linn.) Wight & Arn., when compared with each other with Ayurveda Pharmacopoeia of India showed no much difference. D. gangeticum (Linn.) has more of calcium crystals …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 7, Issue 3, 2020 · pp. 1–15 Read article
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Solanum viarum Dunal: Ethnomedicinal Importance, Phytochemical Profile and Pharmacological Potential — A Comprehensive Review
Abstract: Solanum viarum Dunal, commonly known as tropical soda apple or Sodom apple, is a medicinally important plant belonging to the family Solanaceae. The plant has been widely utilized in traditional medicine systems for the treatment of fever, cough, skin disorders, inflammation, gastrointestinal ailments, and microbial infections. The present review comprehensively summarizes the ethnomedicinal importance, phytochemical profile, pharmacological activities, and pharmaceutical significance of S. viarum. Literature reports indicate that the plant …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 13, Issue 3, 2026 Read article
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Medical Treatment of Central Giant Cell Lesions of the Jaws
Abstract: Central giant cell lesions (CGCLs) of the jaw are benign, non-neoplastic intraosseous proliferative lesions of an osteoclastic origin and an unknown etiology; their conventional treatment is surgical enculeation and curettage with a reported recurrence rate of 15–20%.Because of the inherit problems with the surgical approach (recurrence rate, surgical defect, disfigurement, loss of function, and GA associated morbidity) alternative medical treatments have been proposed over the last 15 years with promising …
Published in Research and Reviews: A Journal of Dentistry · Vol. 9, Issue 3, 2018 · pp. 1–6 Read article
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Treatment Modalities of Planter Fasciitis: A Two Years’ Experience
Abstract: Back-ground: Plantar fasciitis causes soreness or tenderness of the sole of the foot under the heel, which sometimes extends into the medial arch. Objective: A study was conducted to ascertain which treatment modality provides the best results for heel pain patients. Method: The therapies included orthoses, stretching, ultrasonic therapy and local infiltration with a combination of a local anaesthetic and corticosteroid injection. These were included based on the availability of …
Published in Research and Reviews : Journal of Surgery · Vol. 7, Issue 3, 2018 · pp. 21–25 Read article
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Allergic Reaction in Upper Respiratory Tract Infection (Anurjata Janya Swasa Roga) – An Ayurvedic Review and Treatment – A Case Study
Abstract: Respiratory tract infection affects the upper to lower part of the respiratory system including the nose to the alveoli of the lungs. There are two types of infections - upper respiratory infections - affecting the sinuses and throat. Upper respiratory tract infections include: common cold, epiglottitis, laryngitis, pharyngitis, and sinusitis. Lower respiratory tract infection - affects the respiratory tract and lungs. In general, lower respiratory tract infections last longer and …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 11, Issue 1, 2024 · pp. 26–32 Read article
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Deciphering the Roles of Estrogen Receptors and 27-Hydroxycholesterol in BC Progression
Abstract: Breast cancer (BC) ranks among the top causes of cancer-related deaths in women worldwide. Many risk factors of BC are linked to estrogen. Experiments of Beatson in 1896 show the role of steroid hormones as major determinant in BC. Action of steroid hormones is mediated by their receptors including Estrogen receptors (ERs). ERs are part of a subfamily of ligand-regulated transcription factors. Their primary role is to translate hormone signals …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 2, Issue 2, 2024 · pp. 18–26 Read article
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Lesser-Known Metabolites Influencing Ovarian Function, Follicular Development, and Embryo Viability in Dairy Cows
Abstract: The intricate processes of ovarian function, follicular development, and embryo viability in dairy cows are tightly regulated by a complex network of metabolites. While conventional biomarkers, such as steroid hormones, amino acids, and glucose metabolites, have been extensively studied, a growing body of evidence suggests that lesser-known metabolites play pivotal roles in bovine reproductive physiology. Dairy cattle fertility is critical for maintaining optimal milk production and herd sustainability, necessitating deeper …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 15, Issue 3, 2025 · pp. 18–29 Read article
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Consumer Misuse of Cosmeceuticals and Its Role in Adverse Skin Reactions
Abstract: Cosmeceuticals represent a rapidly expanding category of products positioned between cosmetics and pharmaceuticals, offering both aesthetic and therapeutic benefits. However, their widespread availability, aggressive marketing, and perception as inherently safe have contributed to increasing instances of consumer misuse. Misuse includes over-application, inappropriate combinations, prolonged unsupervised use, and use of high-potency active ingredients without dermatological guidance. Such practices have been strongly associated with a broad spectrum of adverse cutaneous reactions ranging …
Published in International Journal of Toxins and Toxics · Vol. 3, Issue 2, 2026 · pp. 1–16 Read article
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Mucormycosis: An Emerging Challenge among COVID-19 Patients
Abstract: Mucormycosis is a rare angio-invasive opportunistic fungal infection that has become an emerging challenge among COVID-19 patients. The higher incidence of mucormycosis among COVID-19 patients has been attributed to hypoxia, pre-existing or steroid induced diabetes, diabetic ketoacidosis, increased ferritin levels, and SARS-CoV-2 or steroid mediated immunosuppression. Other contributing factors include prolonged hospitalization with or without use of mechanical ventilators.The epidemiology and etiopathogenesis of this disease are still evolving. Once infected, …
Published in Research and Reviews: A Journal of Medicine · Vol. 11, Issue 2, 2021 · pp. 34–37 Read article
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An Emerging Cause of Treatable Encephalitis: A Case of Anti-NMDA receptor (NMDAR) Encephalitis
Abstract: Anti-NMDA Receptor encephalitis is the most common type of autoimmune limbic encephalitis known. It is characterised by sub-acute onset of psychiatric symptoms along with refractory epilepsy, orofacial and limb dyskinesia and dysautonomia. High clinical suspicion and appropriate antibody testing in cerebrospinal fluid (CSF) and serum is required for early diagnosis and initiation of immunotherapy. Delay in treatment may lead to significant permanent neuro-deficits as well as mortality. Here, we present …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 7, Issue 3, 2017 · pp. 8–11 Read article
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An Overview of 98 Cases of Idiopathic Granulomatous Mastitis
Abstract: Background: Granulomatous mastitis is an uncommon, benign, chronic inflammatory condition of breast of uncertain etiology. The clinical features mimic tuberculosis and breast cancer that leads to diagnostic and therapeutic dilemma. Its optimal management is still unclear with high recurrence rate. Purpose: The purpose of this study is to present the clinico-pathological features of patients with Granulomatous mastitis and our experience with the medical and surgical treatment of these patients. Methods: …
Published in Research and Reviews : Journal of Surgery · Vol. 7, Issue 1, 2018 · pp. 5–9 Read article
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Effect of Jawarish Zarooni and Sharbat Buzoori in a Diagnosed Case of Nephrotic Syndrome
Abstract: Nephrotic syndrome is a manifestation of kidney disease involving the glomeruli, characterized by oedema, proteinuria, hyperlipidemia and low serum albumin. It may be caused by primary kidney disease such as focal segmental glomerulosclerosis, and mutations in the podocin gene (shown in familial and sporadic forms of steroid-resistant nephrotic syndrome). A study by Michael B. Rothenberg and Walter Heymann M. showed 5-year survey of the incidence of the nephrotic syndrome in …
Published in Research and Reviews : Journal of Surgery · Vol. 9, Issue 1, 2020 · pp. 33–35 Read article