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23 articles for “sepsis”
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Machine Learning Based Automated Detection of Sepsis: A Study
Abstract: Sepsis is a serious condition that occurs when the body's response to infection leads to tissue damage, organ failure, or death. Human body generally releases chemicals into the blood vessels to fight any kind of infection. Approximately 30 million people suffer from sepsis and 6 million people die from sepsis every year according to WHO. Around 4 million 200 thousand new-born and children are affected by sepsis all over the …
Published in Journal of Artificial Intelligence Research & Advances · Vol. 10, Issue 1, 2023 · pp. 1–10 Read article
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Neonatal Sepsis: A Study on Isolated Pathogens and Their Susceptibility Pattern at Tertiary Care Hospital in Rural Setting
Abstract: Neonatal sepsis is one of the most important causes of infant mortality and morbidity. In spite of availability of broad spectrum antibiotics, treating sepsis has become a challenge due to emergence of resistant strains from time to time. The present study is aimed at to isolate the organisms causing sepsis in neonates and their antibiotic susceptibility patterns. From April 2013 to June 2014, 167 blood samples were collected from clinically …
Published in Research and Reviews: A Journal of Medicine · Vol. 5, Issue 2, 2015 · pp. 11–15 Read article
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Post-operative Wound Sepsis and Prophylactic Antibiotic
Abstract: Background and Objectives: Post-operative wound sepsis has been an area of prime interest as tackling it has been a surgeon’s primary role. They have been treating patients in sepsis and preventing sepsis in their operative work. With the advent of modern antibiotics, rate of incidence hasreceded. Timing of antibiotic administration is critical to efficacy. The aim of this study is to evaluate the incidence of post-operative wound infection in A.J. …
Published in Research and Reviews : Journal of Surgery · Vol. 7, Issue 3, 2018 · pp. 9–15 Read article
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Presepsin: A Novel Marker for the Neonatal Sepsis: A Brief Review
Abstract: Neonatal sepsis has been recognized as a global health problem with high incidence across the globe. Delay in the early diagnosis leads to increase in the morbidity and mortality. Several biomarkers have been studied and evaluated for the possible early detection of the neonatal sepsis. In present review, the application of presepsin for the possible potential biomarker for the neonatal sepsis has been evaluated. Keywords: Neonatal sepsis, biomarkers, presepsinCite this …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 8, Issue 1, 2018 · pp. 22–24 Read article
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Systemic Ailment of Oral Focal Sepsis: A Review
Abstract: There are so many etiologies which cause diseases in many parts of the body. One of the most important etiologies is focal sepsis in the oral cavity which can cause a variety of systemic diseases. There are many epidemiological studies which have linked poor oral health with cardiovascular disease, poor glycemic control, low birth-weight pre-term babies and a number of other conditions such as rheumatoid arthritis, respiratory diseases and osteoporosis. …
Published in Research and Reviews: A Journal of Dentistry · Vol. 8, Issue 1, 2017 · pp. 30–35 Read article
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A Conceptul study of Puerperium wsr Puerperial sepsis.
Abstract: The Postpartum period is a critical stage in woman’s life in which a series of changes occur,which impact not only physical health of woman but also psychological and social level.The postpartum period is considered as an indicator of standard of maternal and child health. Routine care in the immediate postpartum period includes meticulous awareness of the medical and social needs of the mother. .It is also very important to understand …
Published in Journal of Nursing Science & Practice · Vol. 11, Issue 1, 2021 · pp. 28–36 Read article
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A Study to Evaluate the Relationship Between the Depth and Extent of Burn Injury with Sepsis
Abstract: In our mortuary, the authors get a lot of cases of bun injury. Among these, most of the deceased die because of the septicaemic shock. Cases of survival after having 45% burn injury also have been reported in our area and in our mortuary, the authors have even got cases with only 10% burn injury (site included face) died due to septicemias. In most of the septicaemic deaths, the burn …
Published in Research and Reviews : Journal of Surgery · Vol. 7, Issue 1, 2018 · pp. 22–24 Read article
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Clinical Spectrum and Prognosis of Patients with Septic Shock
Abstract: Septic shock is the leading cause of mortality in hospital patients. Closer observation and early treatment can influence the outcome. The present study is undertaken to study the pattern of sepsis and the factors affecting morbidity and mortality in adult patients with septic shock in the ICU. Adult patients admitted in ICU, Mamata General Hospital, Khammam, with diagnosis of sepsis during one-year period from August 2012 to September 2013 were …
Published in Research and Reviews: A Journal of Health Professions · Vol. 4, Issue 1, 2014 · pp. 1–4 Read article
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Role of the Surgical-Ward Nurse in Identifying, Escalating, and Managing Postoperative Anastomotic Leak in Colorectal Patients: A Narrative Synthesis in an Australian Nursing Perspective
Abstract: Purpose: Postoperative colorectal anastomotic leak (AL) is one of the most feared complications after colorectal surgery because of its association with sepsis, reoperation, mortality, prolonged hospital stay, delayed adjuvant therapy, and permanent stoma formation. This narrative practice review outlines the frontline role of surgical-ward nurses in the early identification, escalation, and interim management of AL within the Australian acute-care context. Methods: A narrative synthesis of contemporary consensus statements, systematic reviews, …
Published in Research and Reviews : Journal of Surgery · Vol. 15, Issue 1, 2026 · pp. 7–12 Read article
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Concern for Public Health: Periodontitis
Abstract: Periodontitis, a severe form of gum disease, erodes the bone that supports teeth and results in tooth loss. It is caused by bacterial infection and inflammation of the soft tissues around the teeth. About 70% of people 65 years of age and older are affected, on average. Red, bleeding, sensitive gums, foul breath, and receding gums are hallmark indications. Depending on the severity, a full dental examination, the insertion of …
Published in Research and Reviews: A Journal of Dentistry · Vol. 15, Issue 1, 2024 · pp. 22–26 Read article
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Determining the Root Causes of Complications in Hemodialysis
Abstract: As with peritoneal dialysis and kidney transplantation, hemodialysis has been considered one of the most effective therapies for the replacement of kidney function. While this helps to save patients with the disease by decreasing morbidity /mortality/ rates, this medication has some side effects. These may manifest during the dialysis process alongside the ongoing treatment. Avoiding these barriers becomes crucial for improving the patients’ prognosis in this context.We are going to …
Published in Emerging Trends in Metabolites · Vol. 1, Issue 1, 2024 · pp. 27–47 Read article
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Necrotizing Enterocolitis (NEC): A Devastating Neonatal Gastrointestinal Disorder
Abstract: Necrotizing enterocolitis (NEC) represents a formidable challenge in neonatal medicine, particularly afflicting premature infants with its characteristic features of severe intestinal inflammation and necrosis. Despite advancements in neonatal care, NEC continues to exact a heavy toll, standing as a prominent cause of morbidity and mortality in this vulnerable population. Its multifaceted etiology, encompassing prematurity, enteral feeding practices, alterations in microbial colonization, and episodes of intestinal ischemia, underscores the complexity of …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 2, 2024 · pp. 78–83 Read article
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Erythrodermic Psoriasis: A Case Report Highlighting Clinical Features and Management
Abstract: Background: Erythrodermic psoriasis (EP) is a rare and severe variant of psoriasis that presents as widespread erythema, scaling, and systemic complications such as fever, dehydration, and electrolyte imbalances. It requires urgent medical attention due to the risk of life-threatening complications, including sepsis and multi-organ failure. The condition can arise de novo or as an exacerbation of pre-existing psoriasis, often triggered by medication withdrawal, infections, or systemic inflammation. Case Presentation: We …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 2, 2025 · pp. 01–05 Read article
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Characterization of a Broadly Specific LPS-Neutralizing Single Domain Antibody
Abstract: Gram negative endotoxaemia or sepsis remains a lethal challenge to humans and animals, globally. Single domain antibodies (dAbs) have emerged as therapeutic biologics for challenging antigens such as lipopolysachharide (LPS). The present study characterized a broadly specific LPS-neutralising dAb produced from phage display library from LPS-immunized Indian desert camel, for its sequence validation with mass spectrometry. Also, the dAb clone 26 was subjected to co-crystallisation with LPS, extracted from E. …
Published in Research and Reviews : A Journal of Immunology · Vol. 7, Issue 1, 2017 · pp. 1–7 Read article
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A Single-domain Antibody Cross-reacts with Lipopolysaccharide from Diverse Gram-negative Bacteria
Abstract: Gram-negative bacterial sepsis and endotoxemia are the leading causes of morbidity and mortality in animals and humans worldwide, and attempts have continued to design rational therapies. Endotoxin/lipopolysaccharide (LPS)-neutralizing polyclonal and monoclonal antibodies have been produced, but are not free from problems. Single-domain antibodies (dAbs), constructed from the camelid and the shark ‘heavy chain antibodies’ by phage display technology possess favorable features for in vivo applications. The objective of this study …
Published in Research and Reviews : A Journal of Immunology · Vol. 6, Issue 2, 2016 · pp. 29–37 Read article
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A Case-Control Study Examining Determinants of Neonatal Near-Miss in Public Hospitals in Tigray Region, Northern Ethiopia
Abstract: Background: A neonatal near-miss (NNM) is defined as a morbid event that nearly results in newborn death within 28 days postpartum. Every year, four million newborn babies die in the first month of life in low and middle-income countries. However, the determinants of NNM have not been studied in depth in Ethiopia. This study attempted to examine the determinants of NNM in Tigray Region, Northern Ethiopia. Method: We used unmatched …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 7, Issue 3, 2018 · pp. 1–11 Read article
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Exploring the Potentials of Quercetin and Kaempferol combinations along with Regular Antibiotics for the Effective Management of Methicillin-resistant Staphylococcus aureus (MRSA)
Abstract: The methicillin-resistant S. aureus (MRSA) is a bacterium that offers the challenge to numerous antibiotics which leads to a variety of problems, ranging from skin infections and sepsis to pneumonia. The natural products based management somewhat opened hope towards the betterment of the present era where the combination with currently available medicines has been studied clinically. Antibiotics (cefixime, ceftriaxone, erythromycin, ciprofloxacin, cephradine, methicillin, ampicillin, levofloxacin, and amoxicillin) and flavonoids (quercetin, …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 8, Issue 3, 2018 · pp. 6–9 Read article
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Posterior Horseshoe Fistula with Horse-Shoe Ishiorectal Abscess with Bilateral Supralevator Abscess Tract (Extending upto S1)
Abstract: Ano-rectal sepsis is a benign perianal disease. Fistula in ano develops as a sequel to an abscess that does not heal, bursts or is drained inadequately. We are reporting an unusual case of bilateral Ischiorectal abscess/fistula (Horse-shoe) with high supralevator abscess tract (extending upto S1 vertebrae), with a common internal opening posteriorly in the midline and external openings at laterally at both sides. Such atypical abscess/fistula is uncommon and complex. …
Published in Research and Reviews : Journal of Surgery · Vol. 3, Issue 3, 2014 · pp. 9–12 Read article
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A Study of Close Suction Drain Closure in Laparotomy Wound of Intestinal Perforation
Abstract: The most common complication after emergency laparotomy is infection in subcutaneous portion of abdominal incision, sepsis within the peritoneal cavity or infection in both of these areas. The incidence of each is significantly multiplied wherever there has been a peritoneal contamination by bowel or inflammatory process is encountered during abdominal exploration. This prospective study was carried out at Dr. D. Y. Patil Medical Hospital, Pune for a period of 3 …
Published in Research and Reviews : Journal of Surgery · Vol. 5, Issue 1, 2016 · pp. 7–12 Read article
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Interval Laparoscopic Appendectomy: An Observational Study from a Tertiary Care Centre of a Developing Nation
Abstract: Background: Laparoscopic surgery requires an elaborate console and sophisticated laparoscopic instruments such as endoscopic stapler, endoscopic clip, Ligasure, and Harmonic scalpel which attribute to higher cost of surgery. The aim of this prospective observational study was to evaluate the safety profile and outcome of Laparoscopic Appendectomy using basic laparoscopic instruments and low-cost suture materials in a tertiary care hospital of a developing nation. Materials and Methods: This was an observational …
Published in Research and Reviews : Journal of Surgery · Vol. 11, Issue 1, 2022 · pp. 13–18 Read article