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28 articles for “patient-specific dose”
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Estimation of Dose Distribution in Patient Undergoing Hysterosalpingography Fluoroscopy-Guided Medical Procedure
Abstract: Real time imaging allows a wide range of exposure than the conventional radiography for producing diagnostic images. Hysterosalpingography (HSG) is an effective method of evaluating abnormalities of the uterus and fallopian tube using real-time fluoroscopic procedure. The main purpose of this study was to assess the possible radiation dose deposited into different organs of female patients undergoing HSG during the reproductive period. The study was conducted at radiology department of …
Published in Research & Reviews : Journal of Physics · Vol. 9, Issue 3, 2020 · pp. 1–7 Read article
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Evaluation of Patient-Specific Quality Assurance for RapidArc Treatment Delivery Using Dose Volume Histogram
Abstract: This study aims to evaluate the application of dose volume histogram (DVH) metrics within the patient-specific quality assurance (PSQA) protocol in various sites for RapidArc treatment delivery. Forty patients were included in this study, of which twenty each Head and Neck (H&N) and Pelvis Rapid Arc plans were evaluated. Octavius 4D 1500 detector array with vented parallel plate ion chambers was used for this study, which reconstruct the pre-treatment measured …
Published in Journal of Polymer & Composites · Vol. 11, Issue 7, 2023 · pp. 14–22 Read article
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Pharmacokinetics of Levothyroxine and Factors Influencing Its Therapeutic Efficacy in Hypothyroidism: A Comprehensive Review
Abstract: Levothyroxine (LT4) remains the standard therapy for hypothyroidism due to its effectiveness in restoring normal thyroid hormone levels and improving physiological functions. However, its pharmacokinetic profile exhibits considerable variability, which may influence therapeutic outcomes in clinical practice. This review aims to comprehensively evaluate the pharmacokinetics of levothyroxine, including its absorption, distribution, metabolism, and elimination, along with factors affecting its therapeutic efficacy. A structured literature search was conducted using electronic databases, …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 13, Issue 2, 2026 · pp. 27–33 Read article
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Oral Thin Films of Ondanetron Hcl: Formulation and Performance Evaluation
Abstract: This study had the goal to formulate oral polymeric thin film that would dissolve and disintegrate instantly, while also having high mechanical features. These are the most advanced forms of solid dosage forms. Solvent casting was the technique employed to create oral thin films. These are additionally referred to as buccal films/strip, mouth dissolving films, oral thin films, as well as oral strips of paper. These films are suitable for …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 11, Issue 3, 2024 · pp. 1–6 Read article
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Comparative Study of Dosimetry Methodology and Software Tools for Personalized Radionuclide Therapy
Abstract: Purpose: The aim of this review article is to collate the detailed insight of different dosimetry methodology and non-commercial /commercial dosimetry software tools, along with clinical study explored by specific authors, published in recent peer-review journals. The present work is segmented in three sections: i) Literature review of various dosimetry methodologies to evaluate absorbed dose in personalized radionuclide/ radiopharmaceutical therapy. ii) Technical as well as comparative information related to commercial …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 10, Issue 3, 2021 · pp. 9–27 Read article
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Anatomization On Controlled Drug Delivery System
Abstract: Modern target-perception technologies have led to the development of successful controlled drug delivery systems. The process of administering a medication so that it is clinically effective in either people or animals is known as drug supply. Several of the earliest controlled-release systems aimed to achieve a delivery profile that would result in a high drug level in the blood for an extended length of time. When using conventional medication delivery …
Published in Trends in Drug Delivery · Vol. 10, Issue 3, 2023 · pp. 24–32 Read article
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Personalized Therapy Using Drug Delivery Devices
Abstract: The persistent challenge in modern medicine lies in inter-patient heterogeneity, rendering standardized drug dosing protocols suboptimal for many chronic conditions. Traditional pharmacokinetics fail to account for real-time biological fluctuations, leading to cycles of ineffective treatment or dose-limiting toxicity. This paper explores the critical intersection of advanced drug delivery devices (DDDs) and personalized medicine, positioning these technologies as the vital link translating genomic and biological data into tangible, patient- specific interventions. …
Published in Emerging Trends in Personalized Medicines · Vol. 3, Issue 1, 2026 · pp. 53–62 Read article
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Study of benefits and drawbacks of tea
Abstract: Tea is a soft beverage allowed under specifications from World Health Organization (WHO). Over dosage of tea create oxidative stress and liver toxicity at certain concentrations. Patients’ specific speculations prohibit ingestion those deficits procured from vitamin K. This is logical to treat any dosage within standards of intake. In case of alterations in any dose may devoid health benefits like prevention of cancer and cardiovascular diseases, anti-inflammatory, anti-arthritic, anti-bacterial, anti-angiogenic, …
Published in Research & Reviews : Journal of Botany · Vol. 10, Issue 1, 2021 · pp. 1–3 Read article
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IoT Based Pill Dispenser System
Abstract: Real-time data collection and patient database recording have been facilitated by the Internet of Things. One of the most common reasons a treatment plan does not work for a patient is that the drug is not taken at the prescribed time. People 50 years of age and beyond are more likely to suffer from diabetes, high blood pressure, Alzheimer's disease, Parkinson's disease, and other illnesses. For a patient like this, …
Published in Journal of Microelectronics and Solid State Devices · Vol. 11, Issue 1, 2024 · pp. 18–24 Read article
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Therapeutic Drug Monitoring (TDM): An Aspect of Clinical Pharmacology and Pharmacy Practice
Abstract: AbstractTherapeutic drug monitoring or TDM is the clinical pharmacology of measuring specific drugs at designated intervals to uphold a constant level of drug in a patient’s blood circulation, thereby optimizing individual dosage regimens. TDM becomes necessary only for the categories of drug with narrow therapeutic ranges, drugs with marked pharmacokinetic variability, medications for which target concentrations are difficult to monitor, and drugs known to cause therapeutic and adverse effects. On …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 5, Issue 3, 2015 · pp. 27–34 Read article
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Biomedical Approach to Developing and Characterizing Chitosan Nanoparticles Encapsulating Urapidil for Hypertension Management
Abstract: The aim of this study was to create Chitosan Nanoparticles loaded with Urapidil to achieve controlled drug release, enhance solubility, and reduce dosing frequency to improve patient adherence to therapy for hypertension. Urapidil was formulated into nanoparticles via the ionic-gelation method using Chitosan as a polymer, Sodium tripolyphosphate as a cross-linking agent, and filled into hard gelatin capsules after lyophilization. Pre-formulation studies, including melting point analysis and determination of the …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 2, Issue 1, 2024 · pp. 43–51 Read article
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Development and Assessment of Levetiracetam Microspheres Utilizing Synthetic and Natural Polymers: A Biomedical Engineering Perspective
Abstract: In the present study, comparative study of Levetiracetam loaded microspheres using Ethyl cellulose as synthetic and Sodium alginate as natural polymers was done. Solvent evaporation and ionic gelation technique has been successfully employed to produce Levetiracetam loaded ethyl cellulose and sodium alginate microspheres with optimal drug encapsulation that sustained the drug release over a period of time. Based on the pre-formulation studies E1 to E4 and S1 to S4 batches …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 2, Issue 1, 2024 · pp. 1–18 Read article
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Misdiagnosis And Wrong Referral In Chronic Tinnitus Case
Abstract: Tinnitus is one of common and difficult to diagnosed and treat, especially in case with recurrent episode of vertigo . Meniere's disease is one of common diagnosis in tinnitus and vertigo case. Meniere's disease is a chronic inner ear condition primarily affecting individuals between the ages of 30 and 60, characterized by recurring bouts of vertigo, a spinning sensation, accompanied by sensations of fullness or pressure in the ear, hearing …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 13, Issue 3, 2023 · pp. 17–21 Read article
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Mystic Malignant Melanoma Modalities
Abstract: Melanoma is a highly aggressive form of cancer with four recognized subtypes. In about 90% of cases, melanoma is diagnosed as a primary tumor, without signs of spreading. If caught early, the survival rate is quite high, reaching around 94%. However, for metastatic melanoma, the survival rate drops significantly to about 40%. Diagnosing melanoma can be tricky, as it shares features with benign conditions like seborrheic keratosis, benign moles, blue …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 13, Issue 3, 2024 · pp. 1–10 Read article
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Comparative Efficacy and Safety of Safinamide and Rasagiline in the Treatment of Parkinson’s Disease: A Meta-Analysis and Systematic Review
Abstract: Background: Recent studies have suggested Rasagiline and Safinamide monotherapy as potential management options for Parkinson’s disease. Parkinson’s disease, a neurological disorder characterized by tremors and movement difficulties, necessitates treatments aimed at managing clinical symptoms. Levodopa remains the primary effective treatment for Parkinson’s disease symptoms; however, its long-term use often leads to motor complications in many patients. Additional therapeutic drugs, such as dopamine agonists and monoamine oxidase B inhibitors, including Safinamide …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 3, 2024 · pp. 74–91 Read article
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Pharmacological Modeling of New Form of Anti-tumorigenic Medicines in Chemotherapy
Abstract: The existing methods of chemotherapeutic treatment do not permit to calculate the precise dose of medicine and the time of its action on the tumor that leads to unpredictability of result, and, therefore, to the ineffectiveness of the use of treatment itself. Furthermore, the damage of normal cells on chemotherapy becomes the reason for a whole series of complications, connected with side-effects action of chemotherapy. The paper presents the pharmacological …
Published in Trends in Drug Delivery · Vol. 6, Issue 1, 2019 · pp. 31–36 Read article
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Evaluation of Safety of Unani Pharmacopieal Majoon-e-Lana in Cases of Neurasthenia
Abstract: Neurasthenia, referred to as Zof-e-Asaab in the Unani system of medicine, is a functional disorder characterized by generalized weakness of the nervous system. Individuals suffering from this condition commonly experience persistent fatigue, reduced physical and mental performance, low mood, irritability, disturbed sleep, and, in some cases, elevated blood pressure. Although various conventional treatment options are available for symptom management, no specific curative therapy has been established. Furthermore, long-term use of …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 13, Issue 2, 2026 Read article
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Evaluation of Safety of Unani Pharmacopieal Majoon-e-Lana in Cases of Neurasthenia
Abstract: Neurasthenia, referred to as Zof-e-Asaab in the Unani system of medicine, is a functional disorder characterized by generalized weakness of the nervous system. Individuals suffering from this condition commonly experience persistent fatigue, reduced physical and mental performance, low mood, irritability, disturbed sleep, and, in some cases, elevated blood pressure. Although various conventional treatment options are available for symptom management, no specific curative therapy has been established. Furthermore, long-term use of …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 13, Issue 2, 2026 · pp. 37–44 Read article
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RoseRAG-Based Clinical Decision Support System for Precision Medication Safety
Abstract: Medication-related errors remain a major challenge in healthcare, contributing to adverse drug events, increased hospitalization rates, and substantial healthcare costs. Conventional Clinical Decision Support Systems (CDSS) primarily rely on rule-based mechanisms for identifying drug-related problems (DRPs), including drug–drug interactions, contraindications, dosing errors, therapeutic duplication, and medication omissions. Although effective in structured environments, these systems frequently generate excessive context-insensitive alerts, leading to alert fatigue and reduced clinical acceptance. Recent developments in …
Published in Journal of Artificial Intelligence Research & Advances · Vol. 13, Issue 3, 2025 Read article
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Innovative Approaches in Pediatric Drug Formulation Catering to Specialized Need: Review Article
Abstract: This detailed article review examines innovations in pediatric drug formulation, highlighting developments that cater to children’s specific healthcare needs. It covers pediatric pharmacology and advanced solutions like nanoparticle drug delivery and taste-making techniques, focusing on improving the safety, effectiveness, and acceptability of medications for young patients. The review highlights the benefits for patients, including improved adherence to treatment, fewer side effects, and better overall treatment outcomes. It also addresses regulatory …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 3, Issue 1, 2025 · pp. 35–43 Read article