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196 articles for “patient-specific”
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Evaluation of Patient-Specific Quality Assurance for RapidArc Treatment Delivery Using Dose Volume Histogram
Abstract: This study aims to evaluate the application of dose volume histogram (DVH) metrics within the patient-specific quality assurance (PSQA) protocol in various sites for RapidArc treatment delivery. Forty patients were included in this study, of which twenty each Head and Neck (H&N) and Pelvis Rapid Arc plans were evaluated. Octavius 4D 1500 detector array with vented parallel plate ion chambers was used for this study, which reconstruct the pre-treatment measured …
Published in Journal of Polymer & Composites · Vol. 11, Issue 7, 2023 · pp. 14–22 Read article
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Parametric optimization and validation of novel 3D scanning approach for sustainable manufacturing of patient-specific orthodontic retainers
Abstract: The purpose of the proposed study is to identify the ideal procedure parameters for 3D scanning a denture in order to produce customised orthodontic retainers that can be produced sustainably. However, pilot investigations rarely explore parameters like scanning angle, light intensity, or scanning distance. In order to lower acquisition error, the suggested study examines a method for forecasting the ideal values of the previously indicated scanning parameters. Based on the …
Published in Journal of Polymer & Composites · Vol. 12, Issue 2, 2024 · pp. 265–278 Read article
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Design and Fabrication of a 3D-Printed Femur Model: Insights into Mechanical Properties and Implant Research
Abstract: This study is an attempt to analyse the 3D printing of the female femur model of the central India region and provides ample suggestions for bone implant research. This article discusses the design development and experimental validation of finite element analysis (FEA) results with the 3D-printed bone model. Using CT scan data, the FE analysis is executed on a real femur bone of a 25-year-old female of 52 kg weight …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 · pp. 329–338 Read article
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3D-Printed Polymeric Drug Delivery Systems for Personalized Medicine
Abstract: Personalized medicine has revolutionized healthcare by tailoring treatments to individual patient needs. Among the emerging technologies, 3D printing has demonstrated immense potential in fabricating polymeric drug delivery systems with precise control over drug release, dosage, and bioavailability. These systems offer customized therapeutic solutions, improving efficacy while reducing adverse effects. This paper provides an overview of 3D-printed polymeric drug delivery systems, discussing the types of polymers used, fabrication techniques, applications in …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 313–325 Read article
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Personalized Medicines in Pharmaceutics: Drug Delivery System
Abstract: Pharmaceutics personalized medicine is a developing area that seeks to customize medical interventions for specific patients. Instead of a one-size-fits-all approach, personalized medicine focuses on developing treatments that consider a person’s unique characteristics, such as their genetic makeup, environment, and lifestyle. This allows for more effective treatment outcomes, as drugs are specifically designed to work best for each patient, reducing side effects and improving therapeutic results. In pharmaceutics, this involves …
Published in Emerging Trends in Personalized Medicines · Vol. 2, Issue 1, 2025 · pp. 11–22 Read article
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Innovations in Targeted Drug Discovery for Personalized Medicine
Abstract: Personalized medicine is revolutionizing modern healthcare by custoizing treatment plans to match an individual’s genetic makeup, protein expression, and metabomlic characteristics. Also referred to as precision medicine, this approach seeks to improve therapeutic outcomes, reduce adverse effects, and make efficient use of healthcare resources. The incorporation of various omics technologies—including genomics, proteomics, transcriptomics, metabolomics, and epigenomics—has greatly advanced our ability to understand disease biology and molecular variations specific to each …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 3, 2025 · pp. 19–41 Read article
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Precision Medicine Approaches for Cancer Therapy Recent and Advance
Abstract: Recent advances in biotechnology have made it possible to identify intricate and distinctive biological characteristics linked to carcinogenesis. Proteomic and RNA studies, immunological markers, tumor and cell-free DNA profiling, and other methods are utilized to find these traits in order to optimize anticancer treatment for specific patients. In recent years, the focus of clinical trials has shifted considerably to enhance treatment outcomes in cancer therapy. Rather than being primarily centered …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 14, Issue 1, 2025 · pp. 1–11 Read article
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Unveiling The Personality Traits in Substance Use Disorder (SUD)
Abstract: The current case study examines the personality traits of a specific patient in relation to substance use disorders. The individual in question is a 35-year-old male with a history of marijuana consumption spanning the past seven years, along with occasional alcohol consumption. Despite seeking treatment for addiction, he exhibited a complex presentation that involved potential co-occurring personality traits. The main focus of concern revolved around his addiction to marijuana and …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 14, Issue 2, 2024 · pp. 22–31 Read article
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Pharmacokinetics of Levothyroxine and Factors Influencing Its Therapeutic Efficacy in Hypothyroidism: A Comprehensive Review
Abstract: Levothyroxine (LT4) remains the standard therapy for hypothyroidism due to its effectiveness in restoring normal thyroid hormone levels and improving physiological functions. However, its pharmacokinetic profile exhibits considerable variability, which may influence therapeutic outcomes in clinical practice. This review aims to comprehensively evaluate the pharmacokinetics of levothyroxine, including its absorption, distribution, metabolism, and elimination, along with factors affecting its therapeutic efficacy. A structured literature search was conducted using electronic databases, …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 12, Issue 2, 2025 Read article
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Extraction of Impacted Lower 3rd Molars immediately after the Single Visit Endodontic treatment of 2nd Molar - A Case Series
Abstract: Patients who visit a dental clinic often anticipate fewer appointments and quicker recovery times. This expectation is particularly relevant when discussing impacted lower third molars in conjunction with decayed second molars. Dentists often struggle with the decision of whether to start endodontic treatment on the second molar or to proceed with extracting the third molar. This dilemma arises due to the absence of sufficient research or documentation specifically addressing the …
Published in Research and Reviews: A Journal of Dentistry · Vol. 16, Issue 2, 2025 · pp. 6–11 Read article
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Biomedical Coatings: Surface Engineering for Enhanced Biocompatibility and Performance
Abstract: Biomedical coatings have become essential in modern healthcare, significantly improving the performance, durability, and biocompatibility of medical implants and devices. These coatings serve multiple functions, including reducing infection risks, enhancing osseointegration, promoting tissue integration, and enabling localized drug delivery. Advances in surface engineering have led to the development of innovative coatings with superior properties such as antimicrobial resistance, bioactivity, and controlled biodegradation. Various materials are employed in biomedical coatings, including …
Published in Journal of Thin Films, Coating Science Technology & Application · Vol. 12, Issue 1, 2025 · pp. 8–15 Read article
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Microsphere-Based Drug Delivery: A Critical Review of Innovations and Applications
Abstract: Microspheres have emerged as a revolutionary approach in pharmaceutical sciences, offering controlled and targeted drug delivery with improved bioavailability, stability, and patient compliance. These spherical carriers, ranging from nanometers to micrometers in size, can encapsulate both hydrophilic and hydrophobic drugs, enabling sustained and site-specific release. The development of microspheres has been significantly driven by the need to enhance drug efficacy while minimizing systemic side effects. This review provides a comprehensive …
Published in Trends in Drug Delivery · Vol. 12, Issue 2, 2025 · pp. 52–59 Read article
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Artificial Intelligence in Early Diagnosis and Personalized Treatment of Alzheimer’s Disease
Abstract: Artificial intelligence (AI) has become a disruptive technology in the medical care industry, with potential solutions to early diagnosis and customized treatment of Alzheimer’s disease (AD), a progressive neurodegenerative disease and the most prevalent cause of dementia globally. Conventional diagnostic techniques, such as cognitive, neuroimaging and biomarker techniques, are usually limited in the ability to detect disease at its most susceptible stage when treatment interventions are most effective. The recent …
Published in International Journal of Brain Sciences · Vol. 3, Issue 2, 2026 · pp. 15–27 Read article
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Clinical Medicine Done with Clinical Accuracy
Abstract: The advancement of clinical medicine has progressively underscored the significance of accuracy in diagnosis and therapy. This article examines the concept of "Clinical Medicine Administered with Clinical Precision," emphasising how innovations in diagnostics, data analytics, and personalised treatments are transforming the healthcare environment. Clinicians can provide therapy that is not only successful but also personalised to each patient's requirements by combining evidence-based practices with patient-specific factors including genetic profiles, comorbidities, …
Published in Emerging Trends in Personalized Medicines · Vol. 3, Issue 1, 2026 · pp. 6–19 Read article
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AI Activity to Enhance Productivity, Creativity, and Sustainable Development of AI in Healthcare
Abstract: The application of artificial intelligence (AI) in healthcare is revolutionizing the industry by fostering both productivity and creative approaches to patient care and medical research. This study explores how artificial intelligence (AI) is reshaping healthcare by streamlining workflows, improving diagnostic precision, and supporting personalized treatment plans. AI-powered technologies are reshaping the way medical professionals approach patient care, providing tools that not only automate routine administrative and clinical tasks but also …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 12, Issue 1, 2025 · pp. 21–29 Read article
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Stem Cell Therapy: Advancements, Applications, and Future Prospects in Regenerative Medicine
Abstract: Stem cell therapy has come up as a revolutionary technique in regenerative medicine living up to the promise in treating numerous diseases and injuries. The latest discoveries made in the field of stem cell research such as the introduction of gene editing technology like CRISPR and the creation of the 3D bioprinting process have increased the accuracy and efficacy of stem cell-based therapies. Examples include cardiac regeneration and repair of …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 4, Issue 1, 2026 Read article
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Adipofascial Flap Cover For Medial Maleolus Defect
Abstract: Soft tissue defects in the lower third of the leg, particularly over the medial malleolus, pose significant challenges due to poor vascularization and the limited availability of reliable local flaps. Over the past two decades, free tissue transfer has emerged as the preferred option for covering such defects. However, in certain cases, free flap transfer is not feasible due to patient-specific factors, cost constraints, or donor site morbidity. Traditional pedicled …
Published in Research and Reviews : Journal of Surgery · Vol. 14, Issue 1, 2025 · pp. 6–10 Read article
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Advances in Medical Robotics: Surgical Automation and Rehabilitation Systems
Abstract: Medical robotics has emerged as a groundbreaking technology, transforming modern healthcare through advancements in surgical automation and rehabilitation systems. Robotic-assisted procedures machine learning (ML), and artificial intelligence (AI) have all been used to improve patient recovery consequences, reduce invasiveness, and increase surgical precision. These developments have redefined traditional medical techniques by opening the door for more effective, precise, and tailored therapies. By improved dexterity, stability, and vision, surgical robots has …
Published in International Journal of Advanced Robotics and Automation Technology · Vol. 3, Issue 1, 2025 · pp. 31–38 Read article
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Role of the Surgical-Ward Nurse in Identifying, Escalating, and Managing Postoperative Anastomotic Leak in Colorectal Patients: A Narrative Synthesis in an Australian Nursing Perspective
Abstract: Purpose: Postoperative colorectal anastomotic leak (AL) is one of the most feared complications after colorectal surgery because of its association with sepsis, reoperation, mortality, prolonged hospital stay, delayed adjuvant therapy, and permanent stoma formation. This narrative practice review outlines the frontline role of surgical-ward nurses in the early identification, escalation, and interim management of AL within the Australian acute-care context. Methods: A narrative synthesis of contemporary consensus statements, systematic reviews, …
Published in Research and Reviews : Journal of Surgery · Vol. 15, Issue 1, 2026 · pp. 7–12 Read article
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Personalized Therapy Using Drug Delivery Devices
Abstract: The persistent challenge in modern medicine lies in inter-patient heterogeneity, rendering standardized drug dosing protocols suboptimal for many chronic conditions. Traditional pharmacokinetics fail to account for real-time biological fluctuations, leading to cycles of ineffective treatment or dose-limiting toxicity. This paper explores the critical intersection of advanced drug delivery devices (DDDs) and personalized medicine, positioning these technologies as the vital link translating genomic and biological data into tangible, patient- specific interventions. …
Published in Emerging Trends in Personalized Medicines · Vol. 3, Issue 1, 2026 · pp. 53–62 Read article