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9 articles for “niosomes”
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Design and Evaluation of Itraconazole Niosomes
Abstract: The present study was undertaken with an aim to fabricate and characterize and evaluate niosomes of Itraconazole, where the drug is released in a sustained manner for a period of 12 hours. Itraconazole is Class-2 drug having low solubility and have short half-life between 3–4 hours. Due to high first pass metabolism, the drug is rapidly excreted from the body indicating the need of sustained release delivery. To overcome these …
Published in Trends in Drug Delivery · Vol. 9, Issue 1, 2022 · pp. 62–68 Read article
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Innovative Antifungal strategies: Terbinafine hydrochloride in Niosomal carriers
Abstract: Onychomycosis, an infection caused by fungi that affects fingernails or toenails, causes the nails to grow, separate from the nail bed, and become discoloured. While anybody can get, those with weakened immune systems, children and the elderly are especially susceptible. Present study was related to formulate an effective nail lacquer that would treat onychomycosis by utilizing Terbinafine hydrochloride. In this study, niosomes of a medication called terbinafine hydrochloride, an antifungal …
Published in International Journal of Fungi · Vol. 2, Issue 2, 2025 · pp. 1–16 Read article
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Enhanced Iron Removal in Experimental Iron Overload by Nanoniosomes of Desferrioxamine
Abstract: This preliminary study explores the feasibility of employing nanocapsules prepared from nonionic surfactant vesicles (niosomes) as a carrier for an iron-chelating agent, Desferrioxamine (DFO, Desferal), to enhance iron excretion from the body. The methodology consisted of creating an iron overload model in an experimental animal followed by measurement of iron excretion pattern in the urine by atomic absorption spectrophotometry. Niosomes were prepared with span 60: cholesterol:dicetyl phosphate by the lipid …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 5, Issue 1, 2014 · pp. 14–20 Read article
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Novel Nano Polymeric Lipid-Based Carriers for Emerging Pain Management of Rheumatoid Arthritis
Abstract: An inflammatory condition known as rheumatoid arthritis (RA) results in chronic joint inflammation, severe disability, and early death. RA is 3–5 times more common in women than in men, with a global frequency of roughly 0.3 percent–1%. The ultimate goal of RA treatment is to give symptomatic alleviation; there is no recognized cure for RA. NSAIDs are frequently used to treat RA, including indomethacin, diclofenac, ibuprofen, celecoxib, and specifies the …
Published in Research and Reviews : A Journal of Immunology · Vol. 12, Issue 2, 2022 · pp. 30–38 Read article
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Formulation and Characterization of Novel Ethanolic Carrier for Improves Penetration of Serratiopeptidase
Abstract: The aim of present study was to develop ethanolic vesicles of proteolytic enzyme Serratiopeptidase (SRP) by solvent evaporation with high speed homogenization method and to evaluate the Serratiopeptidase ethosomes in treating the topical inflammation. The feasibility of SRP niosomes prepared by using lecithin and ethanol has been successfully demonstrated in this investigation. The entrapment efficiency was found to be influenced by the molar ratio of lecithin: ethanol concentration of SRP …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 2, Issue 1, 2015 · pp. 1–6 Read article
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Recent Trends in Ocular Drug Delivery: Challenges and Approaches
Abstract: Drug topically regulation can be accessed most easily in the eye. When given topically as eye drops, medication ocular bioavailability is quite low. Drug entry into specific ocular locations is complicated by the complex anatomy and physiology of the human eye. Research has long been interested in the topical administration of successful treatments. To provide a suitable ocular penetration and extend the duration of drug residence is their challenging task. …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 11, Issue 3, 2024 · pp. 22–38 Read article
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Applications of Nanotechnology in Advanced Cosmeceuticals
Abstract: Nanotechnology is the study and manipulation of atoms and molecules on the nanoscale, which is approximately 80,000 times smaller than the width of a human hair. By 2015, the global market for products incorporating nanomaterials is projected to reach $2.6 trillion. This field showcases significant progress in research and development by improving product performance and introducing innovative solutions.The usage of cosmetics has increased significantly throughout time, and they are thought …
Published in Recent Trends in Cosmetics · Vol. 2, Issue 1, 2025 · pp. 8–16 Read article
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Nanotechnology-Based Cosmeceuticals for Anti-Aging and Skin Regeneration
Abstract: Nanotechnology has transformed the cosmetic industry of the cosmeceuticals by allowing the production of sophisticated delivery systems that improve the stability, penetration, bioavailability, and therapeutic efficacy of active ingredients in cosmetics. The present review identifies the value of nanotechnology-based cosmeceuticals in anti-aging and skin regeneration, with special focus on the recent developments in nanocarrier technologies and their use in dermatology. Many nanocarriers have exhibited great potentials in enhancing delivery of …
Published in Recent Trends in Cosmetics · Vol. 3, Issue 2, 2026 · pp. 33–45 Read article
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Transethosomes: Rising Technology for Enhancing Transdermal Delivery of Drugs
Abstract: The skin has a total surface area of around 1.8 m2 and serves as the human body's interface with the outside world. The transdermal method of medication delivery has sparked a lot of interest in pharmaceutical research since it eliminates a lot of the issues that come with the oral route. Despite the fact that the skin, especially the stratum corneum, is a barrier to most medication absorption, it does …
Published in Trends in Drug Delivery · Vol. 8, Issue 3, 2023 · pp. 57–63 Read article