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16 articles for “kpt-330”
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Selective Inhibitors of Nuclear Exports—A Novel Anti-Cancer Drug Class: The Review Study
Abstract: For the maintenance of cell homeostasis nucleus-cytoplasmic transport is of great concern. The transport is basically depending on a size of molecule. In different hematological and solid malignancies, the CRM1 is overexpressed so the agents are requiring that particularly inhibit the exportins of nuclear export. This concept favors the SINEs development. The objective of this review study is to understand all about the novel anticancer drugs and their uses in …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 5, Issue 1, 2018 · pp. 29–36 Read article
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Kinetics of Soil Contaminant Degradation Enhanced by Jatropha Tanjorensis Leaf Bio-Stimulant
Abstract: The data obtained from the experiment show a high viability of the plant extracts in the biodegradation process, the maximum specific rate was determined. Also, application of Michael Menten’s equation were also applied, the maximum dissociation rate constant was obtained from lineweaver bulk plot, for both sun-dried and room dried at 100 g of CPED and CPEL as RMAX to be 1000 ppmday-1 and 555.55 ppmday-1 whereas KPTH 3190.16 ppm-1 …
Published in Journal of Catalyst & Catalysis · Vol. 11, Issue 1, 2024 · pp. 01–06 Read article
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High-Performance Biodegradable Films from Bamboo Derived Cellulose Nanofibers and Silk Fibroin: Engineering Sustainable Polymer Composites
Abstract: This research presents the advancement of biodegradable composite films from cellulose nanofibers (CNFs) extracted from bamboo and silk fibroin (SF) derived from Bombyx mori cocoons. CNF/SF composites were fabricated in three different compositions—CS10, CS30, and CS50—via aqueous blending and solution casting, followed by ethanol-induced β-sheet stabilization. Mechanical testing confirmed a considerable enhancement in tensile strength from 72 MPa (CS10) to 112 MPa (CS50), while Young’s modulus improved from 2.4 GPa …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 256–265 Read article
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Contribution Of Indian Historical Technology To Development The AI
Abstract: The Indus Valley Civilization (3300–1300 BCE) was among the first in the world to develop advanced metallurgy. They created bronze tools, copper vessels, and intricate metal ornaments. A testament to ancient Indian metallurgy, this rust-resistant iron pillar, built during the Gupta Empire, still stands without significant corrosion, demonstrating an advanced understanding of material science. The study examines key texts and technologies, including Panini’s Ashtadhyayi (a formal system of grammar resembling …
Published in OmniScience: A Multi-disciplinary Journal · Vol. 15, Issue 3, 2025 Read article
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Persistent Atmospheric and Ecosystem Impacts of Enteric Methane Emissions from Intensive Livestock Production Systems
Abstract: Enteric methane emissions from intensive livestock production systems exert a significant long-lasting influence on atmospheric stability and ecosystem integrity. Recent observations confirm that global methane emissions continued to rise through the early 2020s, with total emissions exceeding 620 teragrams per year by 2024, driven by expanding ruminant production and associated feed systems. Anthropogenic sources accounted for more than 330 teragrams per year, reflecting sustained growth in agricultural and fossil fuel …
Published in International Journal of Atmosphere · Vol. 2, Issue 2, 2025 · pp. 18–38 Read article
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Kinetic Parameters of Corrosion Rate constant for Water-Based Plants for the Inhibition of Metal in Acidic Medium
Abstract: Kinetic parameters of metal inhibition in acidic medium in the presence of water-based plant extracts to monitor corrosion rate characteristics was investigated in this research. The two water-based plasts used are pnematopteris pennigera (GF) and selaginella myosurus (SM) and the mild steel was immersed into the extracts and 1.0M of hydrochloride acid was added to monitor the rate of metal sample corrosion of the analytical grade (raw) HCl (87.3mls) in …
Published in Emerging Trends in Chemical Engineering · Vol. 10, Issue 1, 2023 · pp. 21–35 Read article
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Effect of Various Process Parameters on MRR in Manual Air Plasma Arc Cutting of AISI 1017 Mild Steel using ANN
Abstract: As per recent industrial surveys it is investigated that manufacturing companies define the quality of thermal cutting process by the dimension of work material and cutting surface appearance. Therefore, the surface roughness and material removal rate (MRR) are primarily considered. In this work the effect of three input parameters air pressure (P), cutting current (I) and cutting velocity (v) on material removal rate (MRR) is obtained experimentally. An artificial neural …
Published in Journal of Mechatronics and Automation · Vol. 2, Issue 2, 2015 · pp. 8–14 Read article
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Simulation and Analysis of S-CSRR PIFA for C-band 5G wireless networks
Abstract: In this paper, S-CSRR (Square-Complementary Split Ring Resonator) Planar Inverted F Antenna model is designed and simulated in the HFSS software. For compact and portable devices being preferred in 5G technology, the proposed antenna is helpful. The PIFA antenna with metamaterials (MTM) is beneficial for 4G and 5G wireless communication applications and covers C-band frequencies. The C-band frequency range of 3300-4200 MHz and 4400-5000 MHz is used in the research. …
Published in Journal of Microwave Engineering and Technologies · Vol. 9, Issue 2, 2022 · pp. 15–25 Read article
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Review of Radial Drilling Technology and Viable Prospect in Mature Field Development in the Niger Delta
Abstract: A review of some Niger Delta oil field reservoirs indicates that most of the reservoirs are at the mature stages, thereby vulnerable to challenges such as; coning due to reduced size of the oil column, low oil production and lack of access to the residual oil trapped between existing wells of the mature field. Due to coning occurrences in the Niger-Delta oil field, most wells have been shut-in and a …
Published in Journal of Petroleum Engineering & Technology · Vol. 5, Issue 2, 2015 · pp. 60–66 Read article
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Monitoring the Effect of Temperature and Time on the Characteristics of Metal Sample Corrosion Rate Inhibition using Selaginella myosurus and Pneumatoptens pennigera (GF) Plants
Abstract: This research showcases the effect of temperature and time on the characteristics of metal in terms of weight loss and corrosion rate using Selaginella myosurus or Pneumatoptens pennigera Plant. The weight loss was monitored at temperature range of >300OC to < 385OC and time period of 20hr to 120hr as well as decrease and increase was experienced. However, the research further demonstrates the decrease in weight loss of the metal …
Published in Journal of Thin Films, Coating Science Technology & Application · Vol. 10, Issue 1, 2023 · pp. 10–19 Read article
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Effect of Yoga on Police Personal’s Lung Capacity and Physiological Parameters when Added to their Fitness Training
Abstract: Aim: Occupational hazard of the stress of police duty requires regular rejuvenation of the physical and physiological capacity of the body for handling daily challenges. Hence this pre- and post- intervention effect evaluation was conducted among a cohort of Delhi police personnel to estimate physical and physiological changes with added Yoga during the ongoing fitness schedule for on-duty police personnel. Methods and Material: police personnel n-53, gender male, aged 40-45 …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 10, Issue 1, 2023 · pp. 33–41 Read article
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Population Genetics and Diversity of Human Adenovirus in Two Tertiary Hospitals in Southern Nigeria
Abstract: The study of dynamic changes in genetic heterogeneity can shed light on the evolution of viruses because it is known that the genetic variety of viral populations within their hosts affects disease progression, treatment outcome, medication resistance, cell tropism, and transmission risk. Our study's primary goal is to identify trends in the genetic makeup and variety of human adenoviruses using samples taken from children who attend two distinct tertiary hospitals …
Published in Research and Reviews : A Journal of Immunology · Vol. 12, Issue 3, 2022 · pp. 37–44 Read article
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Determinants of Short Inter-Birth Interval among Child Bearing Age Women in Mekelle City, Northern Ethiopia: Community Based Case Control Study
Abstract: Background: In Ethiopia, where there is high maternal mortality and fertility rate, enhancing optimal inter-birth interval is one of the key strategies to promote the health status of mothers and their children. The purpose of this study is therefore, to understand the determinants for having short inter-birth interval among women in child bearing age. Methods: This unmatched case-control study involved 330 (110 cases and 220 controls) women in child bearing …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 7, Issue 2, 2018 · pp. 6–20 Read article
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A Case-Control Study Examining Determinants of Neonatal Near-Miss in Public Hospitals in Tigray Region, Northern Ethiopia
Abstract: Background: A neonatal near-miss (NNM) is defined as a morbid event that nearly results in newborn death within 28 days postpartum. Every year, four million newborn babies die in the first month of life in low and middle-income countries. However, the determinants of NNM have not been studied in depth in Ethiopia. This study attempted to examine the determinants of NNM in Tigray Region, Northern Ethiopia. Method: We used unmatched …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 7, Issue 3, 2018 · pp. 1–11 Read article
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A Comparative Study to Assess the Nutritional Status of Government and Private Primary Schools’ Children in Pyuthan Municipality, Pyuthan, Nepal
Abstract: The future health of individuals depends on the quality of life of the children. Proper nutrition for school-aged children is very important to their health, cognition and subsequently their educational achievement. A schools-based comparative cross-sectional study was conducted, which has assessed the nutritional status of government and private primary schools’ children in Pyuthan municipality, Pyuthan, Nepal. A total of 330 children, aged 5–12 years of age attending class 1–5 and …
Published in Research & Reviews : Journal of Food Science & Technology · Vol. 6, Issue 2, 2017 · pp. 1–15 Read article
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FT-IR Analysis of Single Walled Carbon Nanotubes based PA12/PMMA Nanocomposites
Abstract: Development of new polymer composites for different applications is gaining interest. In this context, the author has synthesized novel blends and its nanocomposites consisting of Polyamide12 (PA12), Poly methyl methacrylate (PMMA), functionalized and non-functionalized carbon nanotubes by using melt extrusion, followed by injection molding technique. To understand molecular interaction among the blend components, these composites, namely PA12/PMMA blend and PA12/PMMA/SWCNT, SWCNT-OH, SWCNT-COOH nanocomposites are characterized by infrared spectroscopic (IR) methods. …
Published in Research & Reviews : Journal of Physics · Vol. 8, Issue 2, 2019 · pp. 75–82 Read article