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12 articles for “fine-tuning strategies”
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MentaLLaMA: Advancing Mental Health Insights with Instruction-Finetuned Large Language Models
Abstract: The growing prevalence of mental health challenges in contemporary society has highlighted the urgent need for advanced, interpretable, and reliable artificial intelligence solutions that can support mental health assessment and intervention. In response to this need, this research introduces a novel collection of open-source, instruction-tuned large language models (LLMs) specifically designed to facilitate transparent and accurate mental health evaluations. Leveraging a newly developed dataset, which integrates multiple tasks and diverse …
Published in Recent Trends in Programming languages · Vol. 12, Issue 3, 2025 · pp. 08–15 Read article
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Geo AI-Powered Urban Footprints
Abstract: In the contemporary era, building footprints are of paramount importance for accurate and current inventories in the development of infrastructure and geospatial analysis. Traditional methods, relying on manual digitization, were largely unsustainable as the urban regions were growing rapidly. Manual digitization was expensive and lacked geometric precision. This paper introduces an automated, end-to-end GEO AI-powered framework for high-end fidelity building footprint extraction from Google Satellite Data. Our approach for this …
Published in Journal of Remote Sensing & GIS · Vol. 17, Issue 2, 2026 Read article
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CB₁ Reverse Agonists: A Cheminformatic and Patent Landscape Study
Abstract: The endocannabinoid system plays a crucial role in numerous physiological functions, making cannabinoid receptor 1 (CB1) an attractive target for therapeutic development. This review provides a systematic analysis of patent filings from 2019 to 2023 that focus on small-molecule CB1 reverse agonists. It begins with an overview of the endocannabinoid system, highlighting CB1’s involvement in energy balance, pain regulation, and neuroinflammatory processes The main section of the review examines fifteen …
Published in International Journal of Cheminformatics · Vol. 3, Issue 2, 2025 · pp. 33–36 Read article
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AI Hindi Poem Generator
Abstract: The Hindi Poetry Generator project represents a pioneering initiative in the domain of computational creativity, blending machine learning algorithms and natural language processing methodologies to craft poetic expressions in the Hindi language. Rooted in the vast landscape of Hindi literature, this project harnesses the power of deep learning models to generate evocative and culturally significant poetry. At its core, the system relies on neural networks and sophisticated language modeling techniques …
Published in Recent Trends in Programming languages · Vol. 11, Issue 2, 2024 · pp. 10–16 Read article
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The Renaissance and Resilience of CB1 Reverse Agonists: From Central Liabilities to Peripheral Promise
Abstract: Building upon these foundational insights, current research has increasingly focused on refining the pharmacological profile of CB1 reverse agonists to maximize therapeutic benefit while minimizing central adverse effects. The adverse neuropsychiatric outcomes associated with first-generation agents such as Rimonabant including anxiety, depression, and suicidal ideation highlighted the critical role of central CB1 receptors in mood regulation. Consequently, drug development strategies have shifted toward peripherally restricted CB1 reverse agonists that exhibit …
Published in International Journal of Cheminformatics · Vol. 4, Issue 1, 2026 · pp. 30–35 Read article
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Revolutionizing Gastro-retentive Drug Delivery: Exploring Innovative Formulation Strategies and Mechanisms in Floating in Situ Gel Raft Forming System
Abstract: An in-depth exploration of the transformative shift underway in gastro-retentive drug delivery, spotlighting the utilization of Floating Drug Delivery Systems (FDDS) and specifically honing in on the innovative formulation strategies and mechanisms inherent in Floating In Situ Gel Raft Forming Systems. FDDS present a promising avenue for revolutionizing drug delivery efficacy by capitalizing on buoyancy to float atop the gastric fluid surface, thereby extending gastric residence time and improving drug …
Published in Trends in Drug Delivery · Vol. 11, Issue 1, 2024 · pp. 9–21 Read article
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Melanoma Skin Cancer Detection Using Deep Learning
Abstract: Melanoma, a fatal type of skin cancer, is a major global health concern. For better patient outcomes, early and precise detection is essential. A branch of artificial intelligence called deep learning has demonstrated encouraging outcomes in medical image analysis, particularly the identification of skin cancer, in recent years. We present a new method for detecting melanoma skin cancer in this paper by utilizing the ResNet-50 architecture, a deep convolutional neural …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 14, Issue 2, 2025 · pp. 1–9 Read article
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Mindwell: A Psychological Guide for Well-being
Abstract: Mental health is a crucial aspect of overall well-being, yet access to professional therapy remains a significant challenge for many individuals due to various barriers, including cost, availability, and stigma. This research aims to develop an accessible and effective mental health therapy chatbot, named Mindwell Psychology, leveraging the power of large language models (LLMs) and state-of-the-art natural language processing techniques. The primary objective of this study is to create a …
Published in Journal of Artificial Intelligence Research & Advances · Vol. 11, Issue 1, 2024 · pp. 63–77 Read article
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Fake Product Detection Using Convolutional Neural Networks
Abstract: The widespread circulation of counterfeit products in global markets presents a significant threat to both consumer trust and the integrity of established brands. With the advancement of artificial intelligence, particularly deep learning, there is growing potential to develop more sophisticated systems to combat this issue. This study introduces a novel counterfeit detection framework using the VGG16 Convolutional Neural Network (CNN) to distinguish between authentic and counterfeit products through image analysis. …
Published in International Journal of Algorithms Design and Analysis Review · Vol. 3, Issue 2, 2025 · pp. 08–15 Read article
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Recombinant Proteins and Nested Gene Regulation: Nutrient Driven Immune Response and Disease Resistance in Livestock
Abstract: Livestock production systems are increasingly challenged by infectious diseases, metabolic disorders, and environmental stressors that reduce productivity and compromise animal health. Advances in molecular biology and animal nutrition now offer new opportunities to strengthen disease resistance through integrated strategies that combine recombinant protein technologies, gene regulatory mechanisms, and nutrient mediated immune modulation. This review examines how recombinant proteins and nested gene regulation interact to shape nutrient driven immune responses in …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 16, Issue 1, 2026 Read article
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Controlled Release Drug Delivery Using 3D Printing Techniques: A Current Scenario In Personalized Medicine
Abstract: Three-dimensional (3D) printing is particularly influencing the pharmaceutical manufacturing sector in the creation of controlled release drug delivery systems. This technology enables the precise fabrication of personalized medicines with tailored drug release profiles, dosages, and geometries, marking a significant advancement over traditional mass production methods. An array of 3D printing techniques, including extrusion-based, powder-based, and others, can be used to build complex dosage forms that regulate drug release through processes …
Published in Trends in Drug Delivery · Vol. 12, Issue 3, 2025 · pp. 28–43 Read article
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Review of Control Strategies in Lower Extremity Exoskeleton
Abstract: Personal mobility is one of the biggest challenges for ensuring the quality of rehabilitation in the lives of Persons with Locomotor Disabilities (PwLDs) and old aged persons. In order to ensure effective orthotic rehabilitation, there is need to design and develop more and more automated aids and appliances. In order to know the status of research a study has been made on the controllers of lower limb exoskeleton (LLE). In …
Published in International Journal of Robotics and Automation in Mechanics · Vol. 1, Issue 2, 2023 · pp. 9–21 Read article