Search
20 articles for “blood transfusion.”
-
Serum Hepcidin Status of Sickle Cell Disease Subjects with Multiple Blood Transfusion in Nigeria
Abstract: Objectives: No effective physiological mechanism for excess iron excretion is known in humans. Conditions such as sickle cell disease (SCD), where red blood cell transfusion is a frequently employed therapy can subsequently result in ready accumulation and circulation of exogenous iron as non-transferrin bound iron in tissues with possible impairment of iron homeostasis in them. Aim: The influence of multiple blood transfusions on the patterns of iron homeostasis in correlation …
Published in Research and Reviews: A Journal of Medicine · Vol. 9, Issue 2, 2019 · pp. 1–9 Read article
-
Posterior Reversible Encephalopathy Syndrome Secondary to Management of Dimorphic Anemia by Repeated Blood Transfusions: A Case Report
Abstract: Posterior reversible encephalopathy syndrome, popularly known asPRES, is defined as a clinicoradiological syndrome which is characterized by symptoms such as headache, seizures, and altered consciousness and characterized by white matter vasogenic edema affecting the posterior occipital and parietal lobes of the brain .We report a 39-year-old woman who was treated by iron and blood transfusion for dimorphic anemia with a hemoglobin (Hb) level of 2 g/dl. Patient developed three episodes …
Published in Research and Reviews: A Journal of Medicine · Vol. 8, Issue 2, 2018 · pp. 6–8 Read article
-
Voluntary Blood Donation, Future Willingness and Associated Factors Among Attendants of Obstetrics and Gynecology Patients in JIMA University Specialized Hospital, Oromia region, Ethiopia, 2015
Abstract: Background: Hemorrhage is the major cause of maternal death worldwide. This problem is more prevalent in developing countries including Ethiopia. Therefore, availability of adequate blood supply and timely transfusion has paramount importance in reducing maternal deaths. In this aspect, assessing practice, future willingness and associated factors towards voluntary blood donation among attendants can contribute in alleviating the scarcity of blood for transfusion.Objective: To assess voluntary blood donation, future willingness and …
Published in Research and Reviews : Journal of Computational Biology · Vol. 6, Issue 3, 2017 · pp. 1–8 Read article
-
A Study on the Prevalence and Causative Factors of Anemia in Patients Undergoing Maintenance Hemodialysis
Abstract: Anemia is a common and serious issue in individuals with chronic kidney disease (CKD) who are on maintenance hemodialysis (MHD), greatly affecting their overall health and quality of life (QoL). Despite advancements in treatment, anemia remains a challenging issue in this population. This study investigates the prevalence of anemia and identifies the contributing factors in CKD patients on MHD with the aim of enhancing clinical management strategies. This study focused …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 14, Issue 1, 2024 · pp. 73–89 Read article
-
Genetic Detection of Hepatitis C -Virus and Occult Hepatitis B in Patients from Al-Najaf Al-Ashraf Governorate, Iraq.
Abstract: Recently, a noticeable increase in the prevalence of occult Hepatitis B virus (HBV) and Hepatitis C virus (HCV) infections has been observed among clinical cases such as patients undergoing hemodialysis, blood transfusion, liver diseases, and thalassemia worldwide. To limit and control this spread, the present study was conducted to investigate and detect the molecular presence of HCV and occult HBV using the Nested PCR technique, as well as to observe …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 16, Issue 1, 2026 Read article
-
Cytopathology an important aspect of medical diagnosis
Abstract: The scientific subject of pathology examines how illness develops and how infrastructure changes. There are several subspecialties within pathology that focus on the ultimate diagnosis and serve as the cornerstone for the patient's treatment and recovery. It includes blood banking, serology, histopathology, cytopathology, microbiology, biochemistry, and hematology. From the days when a microscope was considered unnecessary to the present, when it is considered essential, pathology has advanced quickly. Surgeons and …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 12, Issue 3, 2023 · pp. 13–18 Read article
-
Blood Cell Saver Machine
Abstract: Intraoperative Cell Salvage (ICS) is a crucial technique in modern surgical practice aimed at minimizing the need for allogeneic blood transfusions. By collecting, filtering, washing, and re-infusing a patient’s own blood lost during surgery, ICS provides a safer and cost-effective alternative to donor transfusion, reducing the risk of transfusion-related infections and immunologic reactions. Initially conceptualized in the early 19th century, ICS technology evolved significantly with the introduction of the Cell …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 15, Issue 2, 2025 · pp. 51–59 Read article
-
A Review Article on the Human Blood Groups in Relation to Healthy Longevity
Abstract: After significant discovery of the ABO blood groups of human beings by Karl Landsteiner, a number of works have been carried out on different types of blood groups like MN type, Q types, etc. and in the same time, number of researches were also carried regarding different aspects of blood groups like its genetic analysis, its inheritance, its role in paternity test, its role in blood transfusion and general physiology …
Published in Research and Reviews : A Journal of Immunology · Vol. 14, Issue 3, 2024 · pp. 1–5 Read article
-
An Overview of Fanconi Anemia: A Genetic Disorder
Abstract: Fanconi Anemia (FA) is a rare genetic disorder caused by DNA repair defects due to pathogenic variants in one of 21 genes. It is the primary cause of inherited bone marrow failure, marked by pancytopenia. Clinically, Fanconi Anemia (FA) is associated with congenital malformations in multiple systems, resulting in progressive bone marrow failure and heightened cancer risk, especially in the urogenital region and the head and neck. There are approximately …
Published in International Journal of Oncological Nursing and Practices · Vol. 2, Issue 2, 2024 · pp. 19–25 Read article
-
Thalassemia and its management – A review article
Abstract: Thalassemia is a hemoglobinopathy burdening India making it earn title of Thalassemia capital of world. Studying last decade, the overall prevalence worldwide and incidence rates have declined but prevalence rates were high in east and Southeast Asian countries. Screening for carriers and affected individuals and genetic counselling are promising approaches for reducing soaring cases and reducing the further spread. Thalassemia affects various organs due to iron overload and haemolysis leading …
Published in International Journal of Tropical Medicines · Vol. 2, Issue 1, 2025 · pp. 60–73 Read article
-
Assessment of Comorbid Illness Among Patients with Chronic Kidney Disease at Selected Hospitals in Madurai
Abstract: Chronic kidney disease (CKD) is a comprehensive term encompassing kidney damage or a sustained reduction in the glomerular filtration rate over a period of three months or longer. CKD is linked to a diminished quality of life, heightened healthcare costs, and premature mortality. The main objective of this study was to identify the comorbid illnesses among the patient with chronic kidney disease and to associate the comorbid illness with their …
Published in Journal of Nursing Science & Practice · Vol. 13, Issue 2, 2023 · pp. 8–13 Read article
-
Use of Condom Tamponade to Manage Massive Obstetric Hemorrhage at a Tertiary Center in Rajasthan
Abstract: Conventionally, postpartum hemorrhage (PPH) is defined as blood loss of more than 500 mL, followed by vaginal delivery and 1000 mL followed by caesarean section. PPH is blood loss which causes a 10% drop in hematocritor which threatens the hemodynamic stability of the patient and needs blood transfusion. The purpose of this study is to evaluate the effectiveness of condom tamponade in the management of massive obstetric hemorrhage and to …
Published in Research and Reviews: A Journal of Health Professions · Vol. 5, Issue 2, 2015 · pp. 26–28 Read article
-
Bloodline: A Efficient Interface for Urgent Blood Availability
Abstract: Blood donation and transfusion have long been critical issues, with blood shortages worldwide leading to many preventable deaths. One of the key challenges contributing to these shortages is the absence of a centralized system for managing blood donations. Traditional methods of blood collection are increasingly outdated in the digital age, highlighting the need for an automated system to streamline donation processes and provide information to those in need. To address …
Published in Journal of Web Engineering & Technology · Vol. 12, Issue 2, 2025 · pp. 28–36 Read article
-
Negative Pressure Wound Therapy and Intermittent Irrigation with Systemic Antibiotic Suppression followed by One-stage Revision in Delayed Periprosthetic Hip Infection Cases: Reinfection Rate
Abstract: Background: Success rate of one-stage revision remains controversial in patients with delayed periprosthetic joint infection after primary cementless hip arthroplasty. We evaluated the reinfection-free efficacy of negative-pressure wound therapy (NPWT) and intermittent pulsatile irrigation (IPR) using chlorhexidine/povidone iodide combined with systemic antibiotic suppression (SAS) followed by one-stage exchange procedure with NPWT in those patients. Materials and Method: Reinfection rate was assessed in randomly selected forty-two cases (group A) with NPWT-IPR-SAS …
Published in Research and Reviews : Journal of Surgery · Vol. 11, Issue 2, 2022 · pp. 7–15 Read article
-
Quantitative Study on the Impact of Holding Duration on Unfiltered FFP Composition
Abstract: Ensuring the safety and quality of transfusion products is a cornerstone of transfusion medicine. The presence of leucocytes in blood components can lead to adverse reactions and increase the likelihood of transfusion-related complications, highlighting the importance of minimizing their content prior to transfusion. Elevated leucocyte levels have been detected in unfiltered fresh frozen plasma (FFP) units prepared from whole blood processed after a short holding time (SHT) – the interval …
Published in International Journal of Antibiotics · Vol. 3, Issue 2, 2026 · pp. 49–63 Read article
-
Stability Study of Fine Powder of Gandhaka Kalpa and Gandhakadi Yoga in the Management of Thalassemia Major-With Respect to Baseline Microbial Diagnostic Modalities
Abstract: Thalassemia is a genetic blood disorder. Thalassemia is the most transfused syndrome worldwide. People with Thalassemia disease are not able to make enough hemoglobin, which causes severe anemia. According to the World Health Organization (WHO), the alpha and beta Thalassemia are the most common inherited single-gene disorders in the world. Adhishthana of the disease Thalassemia is the Beejabhagavayava, which is responsible for the formation of Rakta-Dhatu. Hence the Vyadhi can …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 10, Issue 3, 2020 · pp. 29–37 Read article
-
A Study to Assess the Effectiveness of Practical Guideline on Maintaining Aseptic Technique While Preparing and Administering the Intravenous (IV) Transfusion by the Staff Nurses Working in Medical-Surgical Wards of Selected Government Hospitals of Gujarat State
Abstract: Intravenous fluid administration is not only common in the hospitals; it is also increasingly common in the home for the replacement of fluids, administration of medications, and provision of nutrients when no other route is available. Intravenous therapy is indicated for the administration of drugs, nutrition, infusion solutions and blood products, for correcting metabolic problems and for life-saving measures. Keywords: Intravenous (IV) transfusion, reduction of complications of IV, health Cite …
Published in Research and Reviews : Journal of Surgery · Vol. 6, Issue 1, 2017 · pp. 23–26 Read article
-
Medically Important Hemiptera: Bed Bugs and Kissing Bugs in Human Health.
Abstract: Bed bugs (family Cimicidae) and kissing bugs (subfamily Triatominae) are hematophagous Hemiptera of major medical importance, yet they differ markedly in their public health impact. Bed bugs have resurged globally over the past three decades, with infestations reported from homes, multi-unit housing, hotels, transportation, and healthcare facilities in both high and low-income settings. They are not established biological vectors of human pathogens, but their bites cause pruritic papules, urticarial, and …
Published in International Journal of Insects · Vol. 3, Issue 1, 2026 · pp. 41–49 Read article
-
Prime Editing and Base Editing in Human Hematopoietic Stem Cells Toward Scarless Correction of Monogenic Blood Disorders
Abstract: Monogenic hematological disorders – such as sickle cell disease (SCD), β-thalassemia, and X-linked chronic granulomatous disease (X-CGD) – affect >400, 000 newborns worldwide each year, with a considerable burden in low-resource settings . Although donor-derived allogeneic hematopoietic stem-cell transplantation (HSCT) is widely regarded as curative, its application is limited due to issues of donor availability and graft-versus-host disease (GVHD) and conditioning-related toxicity. DSB-based conventional CRISPR-Cas9 strategies are limited by inefficient …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 4, Issue 1, 2026 Read article
-
Hearing, Speech, and Language Characteristics in a Case with Hemoglobinopathy Secondary to Beta Thalassemia Intermedia
Abstract: Background: Thalassemia is an inherited disorder characterized by a reduced amount or absence of hemoglobin, the oxygen-carrying protein inside the red blood cell. Thalassemia has its types called alpha and beta-thalassemia. Beta thalassemia is a condition in which there is a reduction or deficit in the synthesis of the beta-globin chain of hemoglobin molecules caused by a mutation in chromosome eleven. Beta thalassemia can be broadly categorized into three main …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 14, Issue 1, 2024 · pp. 1–5 Read article