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26 articles for “biological markers”
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Genetics of Bipolar Disorder: A Review
Abstract: Bipolar disorder is a complex psychiatric condition that is thought to have a significant genetic component. This article explores the genetic basis of bipolar disorder, including the potential genetic risk factors and the biological mechanisms that contribute to the development of this disorder. The article discusses the various genetic studies that have been conducted to identify genes and genetic variants associated with bipolar disorder, including genome-wide association studies (GWAS) and …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 10, Issue 1, 2023 · pp. 23–28 Read article
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Comprehensive Review of Moebius Syndrome: Clinical Landscape, Etiology, and Therapeutic Challenges
Abstract: Moebius syndrome, a rare congenital neuromuscular disorder, presents with non-progressive facial weakness, limited eye abduction, and diverse manifestations affecting cranial nerves. This comprehensive review explores its clinical landscape, emphasizing the need for extensive investigations into its elusive etiology and genetic underpinnings. The estimated prevalence is 1 in 250,000 live births, with sporadic cases prevailing. Initial symptoms, evident from birth, encompass difficulties in sucking, and feeding, and absent facial expressiveness. Beyond …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 2, Issue 1, 2024 · pp. 27–38 Read article
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Revolutionizing Veterinary Diagnostics: Nanoparticles and AI Precision
Abstract: The field of veterinary diagnostics is undergoing a transformative revolution propelled by the synergistic integration of nanoparticles and artificial intelligence (AI) precision. Nanoparticles, with their unique physical and chemical properties, present a groundbreaking avenue for enhancing diagnostic sensitivity and specificity in animal healthcare. Engineered to interact with specific biological markers associated with various diseases, nanoparticles offer unprecedented accuracy in early disease detection. Furthermore, their versatility extends to targeted drug delivery, …
Published in Nano Trends – A Journal of Nano Technology & Its Applications · Vol. 25, Issue 3, 2023 · pp. 35–39 Read article
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A Review Article on Obesity: Classification, Biomarkers, Prevention and Treatment
Abstract: Obesity is a complicated condition characterised by an excess of body fat. According to the World Health Organization (WHO) and the National Institutes of Health, a person is overweight if their BMI is between 25.0 and 29.91 kg / m2, and obese if their BMI is greater than 30.0 kg / m2. Drugs such as psychiatric pharmaceuticals, diabetic therapies, antihypertensives, contraceptives, steroid hormones, antihistamines, and protease inhibitors, are linked to …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 9, Issue 3, 2022 · pp. 11–22 Read article
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Gingival Markers as a Tool for Predicting Orthodontic Treatment: A Systematic Review
Abstract: To assess gingival markers as a tool for predicting orthodontic treatment is the main aim of this study. There is a continuous search for methodologies to asses or diagnose the periodontal associated disease, thereby providing a quicker and scientifically proven treatment plan. Clinical evaluation and radiographic reports were the main means of detection of any pathology or disease involving periodontium and the alveolar bone around it. Over the passage of …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 12, Issue 3, 2022 · pp. 41–47 Read article
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Plant Evolutionary Biology: An Insight into Adaptations and Diversity
Abstract: The study of plant evolutionary biology provides crucial insights into the remarkable diversity and adaptation of plants. This review work aims to explore the fascinating world of plant evolution, discussing key concepts, patterns, and mechanisms that have shaped the plant kingdom over millions of years. The review begins by highlighting the immense diversity of plant species, categorizing them into major groups and elucidating their distinctive characteristics. It further examines the …
Published in Research & Reviews : Journal of Botany · Vol. 12, Issue 1, 2023 · pp. 18–23 Read article
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ISSR Marker Analysis of Cypriniform Fishes in Southern Western Ghats
Abstract: The conservation biology and knowledge of the relatedness between populations is particularly important in absorbed breeding programs that attempt to reduce incestuous mating in order to minimize inbreeding. A decline in genetic variation reduces the ability of a population to adapt to environmental changes and decreases its long term survival. The molecular genetic variability among three cyprinids fish species (D. aequippinatus, G. mullya and D. filamentosa) using ISSR markers was …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 9, Issue 3, 2019 · pp. 26–29 Read article
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Computational and Molecular Aspects of DNA Profiling in Forensic and Biomedical Sciences
Abstract: DNA profiling has changed many diverse modern sectors, from health and criminal justice to ancestry research and animal conservation. It is one of the most important scientific instruments of our time. This technique makes it possible to identify people, analyze family relationships, and learn more about biology by looking at unique genetic markers in a person’s DNA. DNA profiling has changed the way forensic science works by making it easier …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 13, Issue 1, 2026 · pp. 14–18 Read article
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The Importance of DNA Profiling Today
Abstract: DNA profiling has changed a lot of sectors, from health and criminal justice to ancestry research and animal conservation. It is one of the most important scientific instruments of our time. This technique makes it possible to identify people, analyse family relationships, and learn more about biology by looking at unique genetic markers in a person's DNA. DNA profiling has changed the way forensic science works by making it easier …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 4, Issue 1, 2026 · pp. 10–14 Read article
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Metabolomics: At a Glance
Abstract: Metabolomics is the branch of science which provides the comprehensive analysis of metabolites in a biological system which in turn is useful as a marker. Metabolomics analysis is useful for ascertaining human health conditions. It will provide an insight to cellular metabolism. Since the metabolome directly reflects physiological states, it can biochemically monitor disease states and assess drug actions, improving the preclinical to clinical translation and focusing on predictability, efficiency …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 4, Issue 1, 2017 · pp. 23–30 Read article
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Precision Medicine Approaches for Cancer Therapy Recent and Advance
Abstract: Recent advances in biotechnology have made it possible to identify intricate and distinctive biological characteristics linked to carcinogenesis. Proteomic and RNA studies, immunological markers, tumor and cell-free DNA profiling, and other methods are utilized to find these traits in order to optimize anticancer treatment for specific patients. In recent years, the focus of clinical trials has shifted considerably to enhance treatment outcomes in cancer therapy. Rather than being primarily centered …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 14, Issue 1, 2025 · pp. 1–11 Read article
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Genetic Diversity of Wheat (Triticum aestivum L.) Germplasm
Abstract: The present investigation was conducted to examine the genetic diversity existing among 30 genotypes of wheat. The experimental design used was randomized block design having four replications. The study revealed wide range of variability and high heritability for all the traits. High estimates of genotypic coefficient of variation (GCV) and phenotypic coefficient of variation (PCV) were observed for number of tillers per plant and yield per plant. High heritability coupled …
Published in Research and Reviews : Journal of Crop science and Technology · Vol. 2, Issue 2, 2013 · pp. 26–36 Read article
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Cellular Mechanisms of Autophagy in Carcinogenesis: A Narrative Review
Abstract: Autophagy is a highly conserved lysosomal degradation pathway essential for cellular homeostasis, metabolic adaptation, and survival under stress. In the context of carcinogenesis, autophagy exhibits a paradoxical and stage-dependent role. During early tumor development, autophagy acts as a tumor-suppressive mechanism by limiting genomic instability, oxidative stress, and chronic inflammation. Conversely, in established malignancies, cancer cells exploit autophagy to sustain growth, survive hostile tumor microenvironments, and resist anticancer therapies. Increasing evidence …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 15, Issue 1, 2026 · pp. 23–28 Read article
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Genetic Variability and Statistical Methods: Key Insights for Computational Genetics Research
Abstract: Genetic variability, defined as the differences in DNA sequences among individuals, serves as the foundation of evolutionary biology and plays a pivotal role in species’ adaptability, resilience, and overall survival. Advances in genomic technologies, particularly high-throughput sequencing, have enabled unprecedented exploration of genetic diversity, fostering the growth of computational genetics. This interdisciplinary field combines statistical methods and computational tools to analyze genetic data, identify patterns, and link phenotypes to genotypes. …
Published in Research and Reviews : Journal of Computational Biology · Vol. 13, Issue 3, 2024 · pp. 19–23 Read article
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In Vivo Biocompatibility and Interfacial Stability of Thermoplastic Polyurethanes and Nanofilled Resin Composites: A Bioanalytical Study of Polymer-Host Interactions Under Dynamic Loading
Abstract: The widespread application of thermoplastic polyurethanes (TPU) and nanofilled resin composites in biomedical devices requires rigorous assessment of their biocompatibility under mechanical stress. While nanofilled composites utilize filler particles (<100 nm) to enhance surface properties and wear resistance, the biological response to these materials in a hydrolytic, enzymatic environment remains a critical area of investigation. Objective: To analyze the in vivo bio-molecular response at the interface of TPU aligners and …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 1112–1119 Read article
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Cathodoluminescence method to scheme optical remains
Abstract: Cathodoluminescence (CL) microscopy replaces light generation by a focused electron-beam so as to visualize optical information at resolution of electron microscope. High-resolution imaging has pursued on strongly cathodoluminescent substrates, such as glass. Method has been applicable for bio- and nano-sciences, said as CL identification of bio-markers within cells as well as ceramic character interpret to describe plasmon components from glass supported devices, given by, sensors, waveguides, plasmonic tweezers, and thin-film …
Published in Journal of Microelectronics and Solid State Devices · Vol. 8, Issue 2, 2021 · pp. 7–14 Read article
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ADVANCEMENTS AND CHALLENGES OF MODERN BREEDING OVER CONVENTIONAL BREEDING
Abstract: Plant breeding dates back thousands of years, when people first deliberately bred plants based on visually pleasing characteristics. The domestication of wild plants aided this process, resulting in the evolution of numerous breeding strategies over time. Conventional breeding, which is distinguished by selective breeding based on superior performance, used procedures such as pure-line selections, mass selection, backcross breeding, recurrent selection, and hybridization. While effective, classical breeding procedures were time-consuming and …
Published in Research and Reviews : Journal of Crop science and Technology · Vol. 13, Issue 1, 2024 · pp. 1–5 Read article
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Personalized Therapy Using Drug Delivery Devices
Abstract: The persistent challenge in modern medicine lies in inter-patient heterogeneity, rendering standardized drug dosing protocols suboptimal for many chronic conditions. Traditional pharmacokinetics fail to account for real-time biological fluctuations, leading to cycles of ineffective treatment or dose-limiting toxicity. This paper explores the critical intersection of advanced drug delivery devices (DDDs) and personalized medicine, positioning these technologies as the vital link translating genomic and biological data into tangible, patient- specific interventions. …
Published in Emerging Trends in Personalized Medicines · Vol. 3, Issue 1, 2026 · pp. 53–62 Read article
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A Study on Automatic Feedback Control by Image Processing for Mixing Solutions in a Microfluidic Device
Abstract: Precise and rapid mixing of chemical and biological reagents is a critical yet challenging aspect of microfluidic systems, often limited by laminar flow conditions and the need for manual or pre- programmed interventions. Existing mixing strategies frequently lack real-time adaptability and closed-loop control, hindering reproducibility and the execution of complex reaction protocols. This work presents an innovative automatic feedback control system utilizing the study on real- time image processing to …
Published in International Journal of Advanced Control and System Engineering · Vol. 3, Issue 2, 2025 · pp. 32–41 Read article
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The Therapeutic Potential of Nutraceutical in Diabetes Management: A Comprehensive Review
Abstract: Diabetes is a long-term and complex condition characterized by high blood sugar levels resulting from inadequate insulin production, ineffective insulin function, or a combination of both. Various nutraceuticals used in clinical settings have shown beneficial impacts on a range of biochemical and clinical markers related to diabetes. In many traditional medical systems, hypoglycemic agents derived from plants are used to treat, manage, and prevent diabetes mellitus. These plant extracts have …
Published in Emerging Trends in Metabolites · Vol. 2, Issue 1, 2025 · pp. 20–27 Read article