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30 articles for “bile”
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Repurposing Liv-52 For Primary Sclerosing Cholangitis: A Computational Docking And Pharmacokinetic Study To Evaluate Its Bile Flow-Regulating Potential
Abstract: Primary Sclerosing Cholangitis (PSC) is a long-term liver disease where the bile ducts become inflamed and scarred over time. This scarring can block the flow of bile, leading to liver damage and, eventually, liver failure. The etiology of PSC remains largely unknown, and current treatment options are limited, highlighting the need for novel therapeutic strategies. This study aims to repurpose Liv-52, a traditional herbal formulation known for its hepatoprotective properties, …
Published in Research and Reviews : Journal of Computational Biology · Vol. 14, Issue 2, 2025 Read article
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Early Postoperative Outcome of Primary Closure versus T-Tube Drainage of Common Bile Duct after Open Choledocholithotomy
Abstract: Background: Choledocholithiasis is the formation of stones in the common bile duct (CBD). These stones are removed by performing CBD exploration and the closure can be done over T-tube or primarily without T-tube. The method of T-tube drainage comes with many complications and hence, nowadays, there is tendency to close CBD primarily to avoid the tube-related complications. Aims: To compare the early postoperative outcome of primary closure versus T-tube drainage …
Published in Research and Reviews : Journal of Surgery · Vol. 8, Issue 1, 2019 · pp. 13–18 Read article
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A Review of Different Surgical Techniques in the Management of Choledocholithiasis
Abstract: Choledocholithiasis is the medical term used to describe the condition where stones are present in the common bile duct. The presence of stones in the common bile duct, known as Choledocholithiasis, can develop due to the creation of stones within the common bile duct or the movement of gallstones formed in the gallbladder into the duct. Selecting the perfect way of clearing common bile duct stone shall be grounded on …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 12, Issue 1, 2024 · pp. 12–20 Read article
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Unani's Perspective on Melancholic Imbalance
Abstract: Unani medicine believed that the human body was composed of three main components—solid organs, liquid humours, and gaseous pneuma. The liquid substances in the body, known as akhlat, are the collection of humours. Each humours do something specific and general works. The balance of black bile (sawda) is essential for maintaining a healthy body, as excess or deficiency can lead to debilitating illnesses. This highlights the crucial role that black …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 10, Issue 2, 2023 · pp. 1–4 Read article
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Isolation of Lactobacillus Acidophilus with A High Acid-Producing Capacity and Its Common Characteristics
Abstract: Some strains of lactobacilli like spore Lactobacillus offer good merits in normalizing intestinal micro biota, resisting selectively to intestinal pathogens, exerting resistance to heat, acid and antibiotics, and are of good storage stability. This research work has been conducted in order to isolate a certain strain of Lactobacillus that offers high resistance to the gastric acid, bile and pathogens, and mutualistic symbiosis with useful intestinal microbes, and identifying its characteristics …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 13, Issue 3, 2023 · pp. 1–6 Read article
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Flying Drone Using KK Flight Controller
Abstract: This paper presents the design, development, and testing of a quadcopter drone using the KK2.1.5 flight controller, with an emphasis on stability and educational value. The KK2.1.5 controller features are inbuilt LCD screen, inbuilt programming, enabling direct configuration and tuning without the need for a computer interface, which makes it highly suitable for beginners and students. The drone is built using a modular frame architecture, which allows for easy replacement …
Published in International Journal of Advanced Control and System Engineering · Vol. 3, Issue 2, 2025 · pp. 20–25 Read article
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Gut Microbial Metabolites in Inflammatory, Metabolic, and Neurologic Disorders.
Abstract: The human gut microbiota transforms dietary and hostderived substrates into a diverse array of metabolites—including shortchain fatty acids (SCFAs), hydrogen sulfide (H₂S), bile acid derivatives, indoles, trimethylamine Noxide (TMAO), branchedchain amino acid (BCAA) derivatives, and lipopolysaccharide (LPS)—that act as key signaling mediators along epithelial, immune, endocrine, and neural axes. These metabolites regulate barrier integrity, energy homeostasis, inflammation, and gut–brain communication and are increasingly implicated in the pathogenesis of inflammatory bowel …
Published in Emerging Trends in Metabolites · Vol. 3, Issue 1, 2026 · pp. 58–64 Read article
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Relation of Thyroid Profile in Gall Stone Disease Patients
Abstract: Introduction: Gallstone disease is a very common gastro-intestinal disorder which is present worldwide. They may form because of many different disorders and the basis for it is impaired metabolism of cholesterol, bilirubin and bile acid and is characterized by formation of stones in hepatic or common bile duct or gall bladder. There has been a discussion, regard to the relation of thyroid disorders and gallstone disease, there are several explanations …
Published in Research and Reviews : Journal of Surgery · Vol. 6, Issue 2, 2017 · pp. 8–12 Read article
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The Pioneers of Greek Medicine: Exploring the Classical Period and Influential Scholars
Abstract: Greek Medicine, an ancient medical system, emphasized holistic approaches, balance, and the interconnectedness of the body and environment. Its contributions to anatomy, pathology, pharmacology, and preventive care continue to shape Modern Medicine. This medical system thrived from around the 5th century BCE until the advent of modern medicine. Greek physicians, such as Hippocrates, Galen and Dioscorides, revolutionized the understanding of the Human Body, Disease, and therapeutic interventions. Central to the …
Published in Research and Reviews: A Journal of Medicine · Vol. 13, Issue 3, 2023 · pp. 1–6 Read article
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Evaluation of Cholesterol Reduction in Probiotic Strain Lactobacillus brevis isolated from Human Fecal Sample by Using Surface Response Methodology
Abstract: Lactobacillus brevis, isolated from human feces was assessed for its in vitro cholesterol reduction ability. The effects of bile salts, inoculum size and contact time in simulated intestinal juice were studied. Central composite design model was utilised to determine the effects of interactions of significant variables on cholesterol reduction. By developing a linear regression model, as a function of growth associated variables in vitro cholesterol reduction was assessed. The results …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 9, Issue 1, 2019 · pp. 40–49 Read article
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An Enhanced Fish Feed Supplemented with Probiotics and Spirulina Formulation for Commercial Production
Abstract: In recent years, the probiotics isolated from fish gut microbiota is used in aquaculture practices as there is a demand to improve the quality of life of fishes. The aim of the study is to isolate probiotic microbe from the gut of Etroplus suratensis and to evaluate the most suitable probiotic for feed formulation. Two bacterial isolates from the gastrointestinal tract (GI) of Etroplus suratensis was evaluated for probiotic properties. …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 10, Issue 2, 2020 · pp. 1–7 Read article
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Concept of Body Fluids (Akhlāt)
Abstract: Unani Tibb is one of the ancient systems of medicine which is also called as the system of Greek medicine. A body fluid or "humor" is that fluid of the body in which our aliment is transformed. In our classical literature, body fluids were termed as Akhlāt (Humors). Humoral theory believes the presence of four humors in the body i.e., blood (dam), phlegm (balgham), yellow bile (safra) and black bile …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 6, Issue 3, 2019 · pp. 12–14 Read article
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Literature Review of Irsal-e-Alaq (Leech Therapy) in Unani and Modern Science
Abstract: The Unani system of medicine is based on the humoral theory (Nazriya Akhlat) postulated by Buqrat. According to this theory, all illness is caused by an imbalance of one of the four body humors that is, blood, phlegm, yellow bile and black bile. Irsal-e-alaq is one of the oldest and widely practiced means of Ilaj-bit-tadbeer for local evacuation of morbid humours. It is a procedure of treatment with the use …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 6, Issue 3, 2019 · pp. 21–29 Read article
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A Novel Technique for Stability Testing of Alliin and Sennosides in Unani Formulations
Abstract: Unani system of medicines is a science which deals with the preventive and promotive aspects of health of human beings and health problems that arise due to factors like ecological and/or environmental, which include humours categorized as blood, phlegm, yellow bile and black bile, and different biological fluids circulating in various vessels of the body. There is significant mandate in drug testing for a specific and precise analytical method for …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 1, Issue 1, 2014 Read article
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A Prospective Observational Study of Prescription and Quality of Life: Gastroesophageal Reflux Disease in Territory Care Hospital
Abstract: Aims and objective: The main aim of the study is to know the quality of life in GERD patients and the management of GERD with the help of prescription patterns and patient counseling. Methodology: After receiving approval from Departmental Research Committee AIPBS with the reference no AIPBS/2021/4586/11 on dated 30 September 2021 and also approved from the Ethics Committee of Biomedical and Health Research, Adesh University with the reference no …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 3, 2024 · pp. 14–21 Read article
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Gut Microbiome Dysbiosis During Metabolic Disorders: Diabetes
Abstract: Understanding the intricate interplay between gut microbiome dysbiosis and diabetes is crucial due to the escalating prevalence and impact of diabetes mellitus globally. This comprehensive review examines the current understanding of this relationship, elucidating how alterations in the gut microbiome composition contribute to diabetes pathogenesis by influencing metabolic homeostasis, immune regulation, and insulin resistance. Dysregulation of gut microbial communities leads to shifts in diversity and abundance, exacerbating chronic low-grade inflammation …
Published in Emerging Trends in Metabolites · Vol. 1, Issue 2, 2024 · pp. 56–75 Read article
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Microbial Symphony: Understanding Biochemical Pathways for Precision Medicine and Beyond
Abstract: The human microbiome, an intricate ecosystem of microorganisms inhabiting the body, is a key regulator of host biochemistry and physiology. This review delves into the complex biochemical pathways influenced by the microbiome, spotlighting critical metabolites like short-chain fatty acids, bile acids, and tryptophan derivatives, which impact immune regulation, energy metabolism, and neurobehavioral functions. By examining interactions between the microbiome and the host, including the influence of genetic factors and metabolite-driven …
Published in International Journal of Antibiotics · Vol. 2, Issue 1, 2025 · pp. 28–43 Read article
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Host-Microbiota Crosstalk in the Rumen: Signaling Pathways for Nutrient Metabolism and Disease Resilience in Dairy Cows
Abstract: The rumen serves as a highly intricate microbial ecosystem, fundamentally responsible for the degradation of fibrous plant materials in ruminant. The intricate host-microbiota crosstalk within the rumen significantly influences nutrient metabolism, growth, and health outcomes in livestock. The interaction between the host and its microbial community, mediated through signaling pathways including the production of short-chain fatty acids (SCFAs), bile acids, and various metabolites, is crucial for enhancing nutrient absorption, fermentation …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 15, Issue 1, 2025 · pp. 29–41 Read article
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Jaundice: Etiology, Clinical Manifestations, Diagnosis, Management, Nursing Care, and Prevention
Abstract: Jaundice is a significant clinical condition marked by a yellow discoloration of the skin, sclera, and mucous membranes resulting from increased bilirubin levels in the bloodstream. Rather than being a disease itself, jaundice represents an underlying disorder involving the liver, biliary system, or hematological processes. Hyperbilirubinemia develops when there is excessive bilirubin production, impaired hepatic uptake, defective conjugation, or obstruction in bile excretion. Jaundice remains a major global health concern …
Published in Research and Reviews: A Journal of Medicine · Vol. 16, Issue 1, 2026 · pp. 32–39 Read article
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Nutrient Sensing and Microbiota Crosstalk: Driving Determinants Shaping Metabolic Stability and Adaptive Physiology for Animal Health
Abstract: Nutrient sensing is a fundamental cellular process that enables animals to adapt to fluctuating dietary inputs while maintaining metabolic homeostasis and health. Recent advances reveal that the gut microbiota functions as an active metabolic partner, producing bioactive metabolites that directly influence host nutrient-sensing pathways and downstream cellular responses. This review synthesizes current knowledge on the integration of key signalling networks, including adenosine monophosphate activated protein kinase (AMPK), mechanistic target of …
Published in International Journal of Molecular Biotechnological Research · Vol. 4, Issue 2, 2026 Read article