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60 articles for “antagonist”
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Synergistic and Antagonistic Effects of Azo-Schiff Base with Some Antibiotics on Gram-Positive Bacterial Isolates
Abstract: Antibacterial resistance has brought an urgent need to find a solution to the problem of antibacterial resistance and increase the effectiveness of antibiotics. Therefore, our current study was aimed to test the three concentrations viz., 0.5 mg/ml, 5 mg/ml and 50 mg/ml of Azo-Schiff base against Grampositive bacteria—Bacillus cereus, Micrococcus lutes, Staphylococcus aureus—to compare the effects of Schiff base alone or along with antibiotics on the viability of bacteria. Our …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 11, Issue 2, 2021 · pp. 25–31 Read article
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Synergistic and Antagonistic Effects of Azo-Schiff Base with Some Antibiotics on Gram-Positive Bacterial Isolates
Abstract: Antibacterial resistance has brought an urgent need to find a solution to the problem of antibacterial resistance and increase the effectiveness of antibiotics. Therefore, our current study was aimed to test the three concentrations viz., 0.5 mg/ml, 5 mg/ml and 50 mg/ml of Azo-Schiff base against Gram-positive bacteria—Bacillus cereus, Micrococcus lutes, Staphylococcus aureus—to compare the effects of Schiff base alone or along with antibiotics on the viability of bacteria. Our …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 11, Issue 2, 2021 · pp. 25–31 Read article
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Effectiveness of Contract Relax Antagonist Contraction Technique and Muscle Energy Techniques to Improve Hamstring Muscles Flexibility in Collegiate Females
Abstract: Background: Flexibility is an essential element of normal biomechanical functioning in daily life. The hamstring muscles are important to control the human movement and are thus involved in activities such as running, jumping and a range of postural actions. The hamstring muscle tightness produces decreased range of motion and reduced flexibility of the pelvis, hip and knee joints. Muscle stiffness of the lower extremities and the subsequent decrease in joint …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 7, Issue 2, 2017 · pp. 16–21 Read article
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Antagonistic Potentials of Actinomycetes Isolated from Coastal Area of Niger Delta against Citrus sinensis (Sweet Orange) and Lycopersicum esculentum (Tomato) Fungal Pathogens
Abstract: The antagonistic potentials of actinomycetes isolated from coastal area of Niger Delta against Citrus sinensis (sweet orange) and Lycopersicum esculentum (tomato) fungal pathogens were investigated. Marine sediment and water samples were collected from ten (10) different points from Onne Light Flow Terminal Seaport situated in Eleme Local Government Area of Rivers State, Nigeria. The actinomycetes were isolated on Glycerol Starch Casein Nitrate Agar using spread plate technique as well as …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 9, Issue 1, 2019 · pp. 4–15 Read article
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A Computational Study to Elucidate the Phytochemicals as An Antagonist Against Pruritis in Psoriasis
Abstract: Objective: Psoriasis is a chronic, non-contagious, auto-immune skin disorder that causes inflammation, pain, and itching in the affected areas. The etiology of this condition is not entirely understood, and while there are treatments available to manage the symptoms, there is currently no cure. The Transient receptor potential cation channel, subfamily Vanillin, member 3 (TRPV3), present in keratinocytes, allegedly had a part in the development of psoriasis-related pain and itching. Specifically, …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 1, Issue 2, 2023 · pp. 49–61 Read article
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A Study Showing the Antagonistic Effect of Lactobacillus casei Against Candida albicans
Abstract: Probiotic strain, Lactobacillus casei was isolated from the probiotic suspension named as Yakult. Strains of Candida albicans were collected from the S.N. Medical College, Agra, India. The antagonistic effect of L. casei against C. albicans was dictated by utilizing the Kirby Bauer disc diffusion technique. Maximum zone of hindrance was estimated by the serial suspension of M.F.S. ≠1.0 against C.albicans and the medium zone of hindrance was seen in the …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 7, Issue 2, 2018 · pp. 35–39 Read article
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In-vitro assessment of plant growth promoting traits integrated with antagonistic activity of biosurfactant producing Bacillus species of oil contaminated soil
Abstract: Researchers are in search of microbial tools having plant growth promoting activity integrated to biosurfactant production potential to develop eco-friendly technique for sustainable agricultural. Presented study was undertaken to characterize the plant growth promoting activity of biosurfactant producing Bacillus species isolated from oil contaminated soil. Bacterial strains were identified as Bacillus licheniformis P1 and Bacillus velezensis P2, on the basis of morphological, biochemical and 16SrDNA gene sequence homology. Biosurfactant producing …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 12, Issue 3, 2022 · pp. 30–34 Read article
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Determining the Antagonistic Potential of Lactobacilli Isolated from Commercial Curd Samples against the E. coli
Abstract: Curd has always been an important source exhibiting a plethora of Lactobacilli. Lactobacilli are rod-shaped bacteria, capable of producing short-chain fatty acids, lactate, and acetate by carbohydrate fermentation process. A study was done to determine the antimicrobial activity of isolated and identified Lactobacilli bacteria from commercial curd samples against standard strains of E. coli. All the 10 samples were found have lactobacilli strains. The antagonistic activity of these strains was …
Published in Research & Reviews : Journal of Food Science & Technology · Vol. 9, Issue 2, 2020 · pp. 27–30 Read article
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Ligand Efficiency in Relation to 3D Physicochemical Characters of Novel HIV-1 Vif Antagonist: An Approach in The Optimization of HIV Drugs
Abstract: AbstractLigand efficiency is a design framework commonly used in drug discovery. Thirty-six (36) newly discovered 1,2,3-triazole analogues as potent new inhibitors of HIV-1 Vif were subjected to quantitative structure-property relationship (QSPR) modeling to predict their ligand efficiencies (LE) in an attempt to improve/optimize it by using some numerical data of HIV-1 Vif inhibitors based on their physical and chemical properties (descriptors). Various 3D physicochemical properties or descriptors were calculated from …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 9, Issue 3, 2022 · pp. 50–59 Read article
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Molecular Docking and Pharmacokinetic Profiling of the Phytocompounds of Jatropha curcas as Antagonist for Salmonella typhi
Abstract: Background: Typhoid is an infection caused by the Gram-negative bacterium, Salmonella enterica serovar typhi. The study assessed the potential use of Jatropha curcas as a typhoid fever therapy alternative to traditional medications. The ability to uncover novel drug indications for currently available medications using in silico methods has increased thanks to the wealth of pharmacological and biological knowledge that is available. Objective: In this study, we assessed the potential inhibitory …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 1, Issue 1, 2023 · pp. 67–81 Read article
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Canker-induced Shifts in Microbial Diversity for Antagonist Mediated Disease Management: A Mini-review
Abstract: Citrus canker is a major bacterial disease caused by Xanthomonas axonopodis subsp. citri in acid group of citrus fruits, causing host plant microbiome to undergo structural-to-functional changes in rhizosphere, endosphere and phyllosphere. The paucity of research breakthroughs on these lines makes such elusive and equally complex issue, still clueless to researchers, unless a renewed thought is given to shift our focus from microbe specific function to plant microbiome in response …
Published in Research & Reviews : Journal of Agricultural Science and Technology · Vol. 10, Issue 2, 2021 · pp. 20–27 Read article
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Protease activated receptor-2 as an imperative target in nociceptive responses: A minireview
Abstract: PARs (protease-activated receptors) are a family of seven-transmembrane G-protein coupled receptor for proteases from circulation, inflammatory cells and endothelial tissues. To date, four members of PAR family have been cloned, namely PAR1 to PAR4. This minireview focuses on role of PAR2 receptor in inflammatory and nociceptive processes. Numerous studies documented for activation of PAR2 receptors through several proteases suggests its role in pain and inflammation. However, mechanism of PAR2 underlying …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 1, Issue 1, 2011 · pp. 8–13 Read article
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Navigating the Principles and Practice of Oral Anticoagulant Therapy: A Comprehensive Healthcare Guide
Abstract: Oral anticoagulant therapy plays a critical role in the prevention and treatment of thromboembolic disorders, including atrial fibrillation (AF), venous thromboembolism (VTE), and mechanical heart valve replacement. This research article aims to provide a comprehensive overview of the principles and practice of oral anticoagulant therapy, focusing on the mechanisms of action, pharmacokinetics, clinical indications, monitoring, and management of associated complications. The cornerstone of oral anticoagulant therapy includes vitamin K antagonists …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 1, 2025 · pp. 76–82 Read article
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Different Herbal Approaches for Treatment of Viral Infections
Abstract: Viral infection like the regular cold, influenza, gastroenteritis, chickenpox herpes, hepatitis (Hep), (HIV), and flu are lethal in the greater part of cases, and treatment with manufactured medications may treat viral infection successfully yet have numerous long-lasting antagonistic results for other imperative organs of the human body. Numerous antiviral drugs as of now in clinical use have a thin range of action, restricted remedial handiness, and variable harmfulness. On the …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 8, Issue 3, 2023 · pp. 14–23 Read article
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Medical Management of Benign Prostatic Hyperplasia
Abstract: Benign prostatic hyperplasia is one of the most prevalent diseases in elderly men. Medical therapies are targeted to relieve obstruction by relaxing smooth muscles(α-blocker) or promoting regression of the disease process (androgen ablation).Three major classes of drugs have been used for the medical management of BPH are α-adrenergic receptor antagonist, hormones and phytotherapy. Selective α 1 receptor antagonist is effective in the treatment of BPH. The development of specific α …
Published in Research and Reviews : Journal of Surgery · Vol. 3, Issue 1, 2014 · pp. 23–25 Read article
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3D-QSAR Studies, Molecular Docking and Adme Property Prediction of Mannosyl Triazoles Used as Potent Antiadhesives of Uropathogenic E. coli
Abstract: Urinary tract infections (UTIs) are among the most common infectious diseases, accounting for almost five million cases annually and causing considerable morbidity and mortality. Escherichia coli is a commensal inhabitant of the mammalian large intestine and the most common cause of UTIs in humans. Increasing incidence of antibiotic-resistant E. coli causing up to 95% of these infections, calls for additional therapeutic considerations. In this study, 3D-quantitative structure-activity relationship (3D-QSAR) analysis …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 6, Issue 1, 2016 · pp. 26–33 Read article
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Role of Gastric Receptors in Gastrointestinal Disorder
Abstract: The established and potential roles of cholecystokinin1 and cholecystokinin2 receptors in gastrointestinal and metabolic diseases are analyzed, along with findings from human studies involving agonists and antagonists. While there is considerable evidence implicating cholecystokinin1R in various diseases such as pancreatic disorders, motility disorders, tumor growth, satiety regulation, and cholecystokinin-deficient states, its specific role in these conditions remains ambiguous. Conversely, the role of cholecystokinin2R in physiological (e.g., atrophic gastritis) and pathological …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 2, Issue 2, 2024 · pp. 37–49 Read article
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Impact of Various Front-line Hypertensive medication on Blood Pressure Control During Maximum Exercise Testing in Coronary Artery Disease Patients
Abstract: It has long been known that blood pressure (BP) and cardiovascular morbidity are related. It is acknowledged that blood pressure during activity may serve as a more reliable indicator than resting blood pressure, which might not accurately reflect blood pressure at other times. Goals: 1) To assess how blood pressure behaves during physical activity in individuals with coronary artery disease (CAD) whose hypertension is managed with first-line antihypertensive medications. 2) …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 2, 2024 · pp. 37–41 Read article
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Efficacy Evaluation of Trichoderma Harzianum, T. Viride, & T. Asperellum: Eco-Biocontrol Agents Against Dry Rot of Potato in Pakistan
Abstract: Fusarium sambucinum is one of the most aggressive fusarium species initiating potato dry rot disease around the world and causing significant economic losses. To alleviate reliance on synthetic fungicides as their long-term use may lead to fungal resistance, biocontrol assays against threatening fungal diseases hold significant importance as an eco-friendly management approach. Antagonists are gradually becoming hotspots and hold broad applicable prospects. Trichoderma harzianum, T. viride, and T. asperellumwere screened …
Published in International Journal of Fungi · Vol. 2, Issue 1, 2025 · pp. 46–50 Read article
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Effects of a Single Dose Inhalation of Ipratropium Bromide, Salbutamol, Salmeterol, Beclomethasone, Budesonide in Stable Chronic Bronchitis: Comparative Study
Abstract: Chronic bronchitis usually treated with long acting bronchodilators and inhaled corticosteroids as monotherapy or in combination. The aim of this study is to assess the efficacy of single dose of β2-agonist (short and long acting), muscarinic antagonist and inhaled corticosteroids on the pulmonary function test in clinically stable chronic bronchitis patients. A total number of 93 (61 males and 32 females) patients who fulfilled the criteria of uncomplicated chronic bronchitis …
Published in Research and Reviews: A Journal of Medicine · Vol. 4, Issue 3, 2014 · pp. 12–17 Read article