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140 articles for “active principles”
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Effect of Beta Asarone–The Active Principle of Acorus Calamus in Neuroprotection and Nerve Cell Regeneration on the Pyramidal Region of Hippocampus in Mesial Temporal Lobe Epileptic Rat Models
Abstract: Epilepsy is a common chronic neurological disorder with seizures. About 1% of people worldwide (65 million) have epilepsy and nearly 80% of cases occur in developing countries [1]. MTLE is the major form of focal epilepsy associated with hippocampal atrophy or sclerosis. For this study we produced a model of mesial temporal epilepsy sterotaxically by inducing kainic acid into the right hippocampus. For this study animals were divided into seven …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 5, Issue 1, 2015 · pp. 19–24 Read article
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Phytochemical constituents of some plants used by the tribals of Dakshin Dinajpur district for medicinal purposes
Abstract: Various phytochemical constituents including alkaloids, phenols, and ascorbic acids were assessed and compared in the four medicinal plants of different families. Four plants used locally for different medicinal purposes were selected for a comparison of their phytochemical constituents. The plants investigated were Clerodendrum viscosum, Moringa oleifera, Cinnamomum tamala and Scoparia dulcis. All theses plants were found to contain the active principles including alkaloids, tannin, saponin, terpenoid, flavonoid, cardic glycoside. Steroid …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 1, Issue 1, 2011 · pp. 1–7 Read article
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An Extensive In vitro Approach in Development of Next Generation Drugs Against Trehalose-6-Phosphate Phosphatases Involved in Pathogenicity of Many Microorganisms
Abstract: Normal 0 false false false EN-IN X-NONE X-NONE MicrosoftInternetExplorer4 AbstractTrehalose-6-phosphate phosphatase (TPP) enzymes implicated in pathogenecity of number of bacteria, fungi and nematodes causing serious diseases such as tuberculosis, candedemias, aspergillosis, elephantiasis and parasitic ones. This study is an effort to target a common pathway critical to pathogenicity of different microbes but entirely absent in vertebrates and to come out with new generation drugs by an extensive in vitro approach. …
Published in Research & Reviews : Journal of Herbal Science · Vol. 7, Issue 1, 2018 · pp. 32–43 Read article
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Anti-tumour Effects of Green Synthesis of Silver Nanoparticles from Helicteres isora L: In Vitro Approach
Abstract: Green synthesized silver nanoparticles preparation from 1mM AgNo3 solution through the fruit extract of Helicteres isora. in the range of 24–30 nm with increased stability and enhanced anti-tumour potency were reported in this present study. Green synthesized silver nanoparticles from fruit extract of H. isora (Hif-AgNPs) were characterized by using UV-VIS absorption spectroscopy and the morphology of the nanoparticles was characterized by transmission electron microscopy (TEM). The anti-tumour efficacy was …
Published in Trends in Drug Delivery · Vol. 5, Issue 1, 2018 · pp. 1–5 Read article
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Comparative Study of Medicinal Properties of Indigenous Drugs from Species of Strychnos L. and its Scope in the Field of Homoeopathy- a Pilot Study
Abstract: AbstractPlant kingdom is a rich source of drug. Different medical systems prepare drug from plants and employ them according to their own pharmacological principles. Genus Strychnos L. belongs to Loganiaceae family and contains many active principles like brucine, strychnine, icajine, toxiferine, loganine, etc. Modern medicine and AYUSH use genus Strychnos L. to prepare drug against several disease conditions like ulcers, neurological disorders, skin diseases, parasitic infestations etc. Work has been …
Published in Research & Reviews : Journal of Botany · Vol. 9, Issue 1, 2020 · pp. 13–19 Read article
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A Novel Method for Isolation of Plumbagin
Abstract: Normal 0 false false false EN-US X-NONE X-NONE MicrosoftInternetExplorer4 /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-qformat:yes; mso-style-parent:""; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-para-margin:0in; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:minor-fareast; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi;} The Plumbagin (5-hydroxy-2-methyl-1, 4-naphthoquinone) is the characteristic naphthoquinone present in the different species of the plant Plumbago (Family: Plumbaginaceae) commonly known as Chitrak in India. Plumbagin is …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 1, Issue 2, 2011 · pp. 1–6 Read article
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A Review on Phytochemical and Pharmacological Properties of Anacyclus Pyrethrum (Akarkara)
Abstract: The wild species Anacyclus pyrethrum, or A. pyrethrum, is a member of the Asteraceae family. It is commonly known as Akarkara. It originated in Spain, Morocco, and Algeria, and has since spread to Sri Lanka, India, Ukraine, Germany, Myanmar, France, and Poland. It is the benefits of bioactive compounds of plant found the chemical makeup, analgesic, anti-inflammatory, and wound-healing effects of hydroalcoholic extracts of A. pyrethrum’s roots, seeds, leaves, and …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 12, Issue 1, 2025 · pp. 102–110 Read article
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Polyherbal Formulation: Preparation, Standardization and Neuropharmcological Screening
Abstract: The Standardization and Pharmacological evaluation of herbal formulations is crucial in order to evaluate the quality, purity, safety and efficacy of drug based on the amounts of their active principles. The aim of present work is to prepare and standardize herbal formulation and also to evaluate its neuropharmacological potential on rats. The formulation was prepared by mixing 20 herbs in equal proportion and was made homogenous. Furthermore, the formulation was …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 1, Issue 3, 2014 · pp. 15–18 Read article
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Software Quality Assurance and Systemic Review
Abstract: AbstractQuality is most of the important factor in industries now a day. Software industries have to work on quality assurance and control, as day by day variety of software is developed and drawn in the market. To satisfy the growing demand and need of customer in today's competitive world companies have to concentrate on the software quality, which is checked while the development of software. Software quality depends upon customer …
Published in Journal of Software Engineering Tools & Technology Trends · Vol. 7, Issue 3, 2020 · pp. 41–46 Read article
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Seasonal Variation in the Phytochemical Constituents of Two Ajuga Species
Abstract: Medicinal plants are the natural repositories of secondary metabolites that can be used for therapeutic purposes. The content of these secondary metabolites or phytochemical constituents varies at different growing seasons of the plants. The phytochemical constituents of Ajuga bracteosa and Ajuga parviflora varied significantly in their proportion at different stages of development and among different populations. The content of phenols and flavonoids was found to be maximum at the flowering …
Published in Research and Reviews : Journal of Crop science and Technology · Vol. 6, Issue 3, 2017 · pp. 25–31 Read article
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Analysis of Genetic Basis for Morphological Variations in Normal and Tissue Cultured Plants of Andrographis paniculata in Association with or Without Arbuscular Mycorrhizal Fungi using AFLP Markers
Abstract: Andrographis paniculata Nees, a member of Acanthaceae, is one of the important medicinal herbs. The active principle, Andrographolide esters has a paramount importance in pharmaceutics. Morphological variants have been reported both in natural populations collected from various geographical areas and micropropagated plants raised through tissue culture that need to be analyzed with proper molecular tools. In order to facilitate reasoned scientific decisions on its management, conservation and prepare for a …
Published in Research & Reviews : Journal of Botany · Vol. 8, Issue 1, 2019 · pp. 1–11 Read article
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A Review on Dairy Products by Microbial Considerations in Dairy Processing
Abstract: The microbial quality of air in a dairy processing factory was assessed to determine the role of air as a source of contamination and deterioration of milk and milk products. When examining microbial activity in dairy products,not only for shelf stability but also for organoleptic considerations and the capacity for fermentation to occur, raw material assessments in plant monitoring and, in certain situations, end-product testing are critical. “Milk” is a …
Published in Research and Reviews : Journal of Dairy Science and Technology · Vol. 11, Issue 1, 2022 · pp. 1–6 Read article
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Formulation Boswellia serrata and Commiphora mukul Extract Gel for Topical Inflammation
Abstract: Inflammation and rheumatism remain serious health problems in the present era. In the present attempt, the authors developed anti-inflammatory gel which gives benefit of faster permeation for quicker action. This anti-inflammatory gel is very useful for the arthritis patients. For the formulation purpose Boswellia serrata (Shallaki) and Commiphora mukul (Guggul) were selected because very less work has been done on these plants and for synergistic effect known of herbal extracts …
Published in Research & Reviews : Journal of Herbal Science · Vol. 4, Issue 2, 2015 · pp. 1–8 Read article
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HPTLC: An Emerging Technique in Herbal Medicine
Abstract: Herbal medicine and their formulations are extensively used since time immemorial in developing and well developed countries. Their quality assessment is of benefit not only in research but also in practice. However, quality control of these herbo-mineral preparations is more difficult than that of conventional drug due to chemical complexity and natural variability of product and raw materials. Furthermore, the active principles are, in most cases unknown and selective analytical …
Published in Research & Reviews : Journal of Herbal Science · Vol. 4, Issue 2, 2015 · pp. 25–37 Read article
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Phytochemical Study of Seed Extract of Phaseolus vulgaris
Abstract: Phaseolus vulgaris L. is usually known as kidney beans. It is a green medicinal plant that has a place with the family Fabaceae. Conventional arrangement of medication utilized this for the cure of few sicknesses such as diabetes, malignant growth, kidney issues, and so forth. For the present research work, the powdered plant seeds were dissolved consecutively in various solvents in increasing polarity order. Different phytoconstituents such as saponins, flavonoids, …
Published in Research & Reviews : Journal of Herbal Science · Vol. 9, Issue 3, 2020 · pp. 11–16 Read article
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Phytochemical Screening of Coccinia indica
Abstract: It is a code of conduct that ensures the correct substances in the correct amount for the desired therapeutic effect such as safety, quality, and efficacy. There have evidence which suggest that Coccinia indica has therapeutic effects that range from antihyperglycaemic and antiureogeniceffects in diabetic, ovicidal and repellent properties. The active principles are extracted from plant drugs and purified for therapeutics. Detection of nature of adulterants carried out by various …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 6, Issue 2, 2019 · pp. 30–38 Read article
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Sarpa Gandha Choorna: Medicinal & Pharmacognistical Review
Abstract: Sarpagandha is a evergreen shrub belong to Apocyanaceae. It is a medicinal plant used in Ayurvedic and Modern system of Medicine. Rauwolfia serpentina hold central position in world of pharmaceutical science due to presence of various alkaloids. This herb consist of number of active principle which have medicinal value so used in many disorders of various system.
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 13, Issue 1, 2022 · pp. 16–22 Read article
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Morphometric Divergence of Garra mullya (Skyes, 1839) Populations from the Preferred River System of Southern Western Ghats Region, Tamil Nadu, India
Abstract: The present study aims to describe the phenotypic divergence of Garra mullya from the preferred river sites of Southern Western Ghats, Tamil Nadu, India. A total of 18 morphometric characters were analyzed within populations from different localities. The species-wise and population-wise descriptive statistics viz., minimum, maximum, mean, standard deviation, the coefficient of variation (CV) of all morphometric traits, the multivariate coefficient of variation (CVp) and the principle component analysis were …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 7, Issue 3, 2017 · pp. 7–13 Read article
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Construction and Development of pSB111 Bar Plasmid Vector for Activation Tagging
Abstract: To get desired traits and to know the precise expression patterns of genes in the plant, Agrobacterium tumefaciens has been widely employed in the generation of transgenic plants using plasmid vectors. Many methods are come forward to establish the gene expression of unknown genes but in these techniques gene alteration isthe main drawback orsometimesit islethal to organisms also, to overcome these problems activator tag method developed to know the specific …
Published in Research & Reviews : Journal of Botany · pp. 1–6 Read article
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Pharmacodynamics and Drug–Receptor Interactions: Integrating PK/PD Modeling with Modern Drug Development
Abstract: Understanding drug action requires an integrated perspective of pharmacodynamics and pharmacokinetics, which together determine therapeutic efficacy and safety. This review provides a comprehensive overview of the mechanisms underlying drug action, with particular emphasis on drug–receptor interactions and their role in modulating physiological responses. Drugs exert their effects primarily through interactions with specific biological targets, including receptors, enzymes, ion channels, and transporters, resulting in a spectrum of desired and adverse outcomes. …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 2, 2026 · pp. 33–47 Read article