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100 articles for “Tuberculosis Tuberculosis”
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Possible Risk Factors Associated with Tuberculosis Treatment Failure Among Patients Attending Tuberculosis Treatment Centers in Kano State, Nigeria
Abstract: The widespread failure of tuberculosis chemotherapy has led to an increase in mortality and morbidity associated with tuberculosis infection. This study was aimed at assessing the possible risk factors associated with tuberculosis treatment failure in patients attending Aminu Kano Teaching Hospital (AKTH) and Infectious Disease Hospital (IDH), Kano State. Treatment outcomes of the 436 tuberculosis patients attending selected hospitals in 2018 were obtained using a retrospective study (review of the …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 13, Issue 2, 2023 · pp. 1–9 Read article
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Assessment of exacerbation of Depression in pulmonary tuberculosis patients by using PHQ-9 scale at Tertiary Care Hospital
Abstract: Context: Depression leads to more dysfunction and stress, which could affect the patient's life condition. Tuberculosis is a leading cause of comorbidity with depression. Those suffering from tuberculosis and depression are at higher risk of bad health-seeking nature, resulting in higher morbidities, drug resistance, and mortality. The relationship is not well established. Aims: To identify multiple variables/ dependent factors affecting depression respectively in tuberculosis patients and check the medication adherence …
Published in International Journal of Pathogens · Vol. 1, Issue 2, 2024 · pp. 24–31 Read article
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Assessment of Loneliness and Depression Status of Tuberculosis Patients Who Applied to Sakarya Tuberculosis Control Dispensary
Abstract: Background: This study was planned by using a descriptive and cross-sectional research model in order to examine the loneliness and depression status of tuberculosis patients who applied to Sakarya Tuberculosis Control Dispensary. Materials and Methods: The study was carried out with 100 tuberculosis patients who applied to Sakarya Tuberculosis Control Dispensary between September 2016 and February 2017, after obtaining institutional permission and ethics committee approval. Analysis of data collected using …
Published in Journal of Nursing Science & Practice · Vol. 10, Issue 1, 2020 · pp. 1–7 Read article
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GeneXpert MTB/RIF Assay (PCR Mycobacterium Tuberculosis): A Revolution in Management of Tuberculosis
Abstract: Background: Workup of pulmonary tuberculosis depends upon sputum microscopy. Sputum microscopy is less sensitive, human resource dependent and time consuming. Sometimes, it lead us to a delay in the diagnosis and may result in the spread of the disease. This seriously disturbs TB control program. There is a need for a more sensitive method. Similarly, early detection of rifampicin resistance is also of utmost importance to prevent MDR strains from …
Published in Research and Reviews : A Journal of Immunology · Vol. 8, Issue 2, 2018 · pp. 8–12 Read article
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Pathogenesis, Treatment and Molecular Mechanisms for Development of Multidrug-resistant (MDR) TB as well as Identification of MDR Mycobacterium Tuberculosis
Abstract: Normal 0 false false false EN-US X-NONE X-NONE Tuberculosis (TB) is a medical, social, and economic disaster of huge magnitude in the world. Prevalence of TB has increased due to poverty, population growth, migration and a high number of TB cases in HIV positive individuals. High prevalence rate of M. tuberculosis strains with multidrug resistance (MDR) is a serious problem as global emergency. Strains of M. tuberculosis resistant to both …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 3, Issue 1, 2013 · pp. 16–38 Read article
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Understanding the Impact: Adult BCG Vaccination in the Fight Against Tuberculosis
Abstract: Tuberculosis (TB) remains a big global health challenge, with significant mortality rates, especially in developing nations. India holds most TB cases throughout the globe. As HIV rates, multidrug-resistant tuberculosis (MDR-TB), and extensively drug-resistant tuberculosis (XDR-TB) continue to increase, the situation is deteriorating. These all come in the way of the End TB epidemic campaign by the World Health Organization (WHO) by 2030. Immunology and vaccinology represent critical fronts in TB …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 3, 2024 · pp. 1–6 Read article
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First Insights into Whole Genome Sequencing of the Mycobacterium tuberculosis Complex: Molecular Diversity and Drug Susceptibility Patterns in Senegal
Abstract: Background: We conducted a bibliographic analysis of the Mycobacterium tuberculosis complex (MTBC) in sub-Saharan Africa, which included the analysis of 8,139 genomic sequences from 34 of the 49 sub-Saharan African countries. Notably, only one complete sequence from Senegal was identified, which had been generated in the United States. Our primary objective was to utilize whole genome sequencing (WGS) to detect resistance in anti-tuberculous strains of the MTBC in Senegal. This …
Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 1, 2025 · pp. 1–14 Read article
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Pathogenesis and Treatment of Tuberculosis (T.B) Disease
Abstract: Tuberculosis (TB) is an infectious illness spread through the air that is caused by organisms from the Mycobacterium tuberculosis complex. M. tuberculosis is a lung infection in primary stage, but it can infect any area of the body. M. tuberculosis infection can progress from latent TB infection, in which the bacteria are isolated within granulomas, to infectious infection, in which the patient develops symptoms such as cough, fever, night sweats, …
Published in Research and Reviews : A Journal of Immunology · Vol. 11, Issue 3, 2021 · pp. 42–48 Read article
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Disseminated Tuberculosis in an Infant: A Case Report
Abstract: Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis. Even though tuberculosis among pregnant woman is not uncommon, documented cases of congenital tuberculosis are rare. It is because placenta forms a protective barrier against the invasion of foetus by the organism. Although rare, congenital tuberculosis should be distinguished from more frequent acquired neonatal tuberculosis. Diagnosis of neonatal tuberculosis is difficult as sputum is generally not available for examination. Gastric aspirate …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 3, Issue 3, 2013 · pp. 5–7 Read article
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Decoding the Mycobacterium tuberculosis–Macrophage Interplay: From Immune Defense to Pathogen Persistence
Abstract: Tuberculosis (TB) is a chronic infectious disease caused by Mycobacterium tuberculosis (Mtb) and has been responsible for over one billion deaths worldwide over the past two centuries, remaining a major global health challenge despite advances in diagnosis and treatment. The barriers that make tuberculosis difficult to treat and eliminate are inextricably tied to its intracellular habitat. However, a research gap lies in understanding the molecular mechanisms of its survival and …
Published in International Journal of Pathogens · Vol. 3, Issue 2, 2026 Read article
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A Narrative Review on Tuberculosis Disease Transmission, Treatment, Prevention, Emergency Care, and Vaccine Allocation in Second Highest Populated Country (India)
Abstract: Tuberculosis, an airborne illness caused by Mycobacterium tuberculosis, is a highly contagious disease primarily impacting the lungs, though it can also affect other body parts, excluding hair and nails. There are two main types of tuberculosis: pulmonary tuberculosis (PTB), which targets the lungs, and extrapulmonary tuberculosis (EPTB), which involves other areas such as lymph nodes, bones, joints, and the nervous system. The theme for World Tuberculosis Day in 2024 is …
Published in International Journal of Emergency and Trauma Nursing and Practices · Vol. 2, Issue 1, 2024 · pp. 7–13 Read article
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AI in Healthcare: Drug Delivery in Tuberculosis
Abstract: Tuberculosis (TB) , mainly caused by Mycobacterium tuberculosis, remains a major global health burden, accounting for millions of new infections and deaths each year. Although progress has been made in diagnosis and treatment, the growing threat of multidrug-resistant (MDR) and extensively drug-resistant (XDR) TB makes disease control increasingly difficult. Conventional diagnostic approaches such as chest X-rays, sputum smear microscopy, and culture methods continue to play an important role, but they …
Published in Trends in Drug Delivery · Vol. 13, Issue 1, 2026 · pp. 9–17 Read article
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Standard Diagnostic Procedure for Tuberculosis: A Review
Abstract: Normal 0 false false false EN-US X-NONE NE Despite continuous effort in monitoring and treatment of tuberculosis, the disease remains a major public health issue. Rapid diagnosis and appropriate therapies become the first priorities in controlling the growing epidemics. The bedside decision on the initiation of anti-tuberculous drug therapy are based on epidemiologic, clinical, radiolographic, and/or histological findings, which can generally be supported by a rapid microbiologic test, commonly a …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 3, Issue 3, 2013 · pp. 34–40 Read article
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Computer-Aided Drug Design on Tuberculosis
Abstract: Currently, India's Directly Observed Treatment Short Course (DOTS) program is the world's largest and fastest-growing initiative for treating medical patients, second only in terms of population coverage. The main obstacles to TB control in India are inadequate primary healthcare in rural regions of many states, unregulated private treatments resulting in extensive misuse of first- and second-line TB medications, the spread of HIV, a lack of political commitment, and, most importantly, …
Published in Research and Reviews : A Journal of Immunology · Vol. 14, Issue 2, 2024 · pp. 22–31 Read article
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Concept of Pulmonary Tuberculosis in Greco-Arab (Unani) Medicine
Abstract: Tuberculosis, one of the oldest diseases known to effect humans have preceded recorded history since the changes of spinal tuberculosis in the skeleton of a Neolithic man was described. The development of Greek medicine (Unani medicine) has been the hallmark in the history of medicine and it was with this civilization of ancient Greece that the history of tuberculosis really begins. Hippocrates (460–375 BC) owes to the medicine the art …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 7, Issue 2, 2020 · pp. 1–9 Read article
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Detection and Identification of Fungal Pathogens by Multiplex PCR in Pulmonary Tuberculosis Patients in Kancheepuram
Abstract: Tuberculosis is a common infection in developing countries. Pulmonary tuberculosis is the most commonly associated disease in cases of secondary aspergilloma. Fungus infection is gradually becoming commoner and has been difficult to evaluate since diagnoses were seldom confirmed. Multiplex PCR method provides a rapid, simple, and reliable alternative to conventional methods to identify common clinical fungal isolates. Hence, this study was taken up to find the fungal co-infections among TB …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 3, Issue 2, 2013 · pp. 1–5 Read article
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Prevalence of Adverse Drug Reactions and Risk Factors Associated with first Line Anti- Tuberculosis Drugs
Abstract: Background: The recommended first line treatment of active tuberculosis (TB) consists of rifampicin (R), isoniazid (H), ethambutol (E) and pyrazinamide (Z). The regimen is highly effective in treating active TB however it is associated with various adverse drug reactions (ADRs) posing undeniable challenges to therapy success. Objectives: To determine the prevalence of ADRs and risk factors associated with first-line anti-tuberculosis medications. Methods: A quantitative cross-sectional descriptive study conducted at the …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 12, Issue 2, 2022 · pp. 9–16 Read article
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Diagnostic Methods for Hepatitis-C Virus and Tuberculosis Coinfection among HIV Infected Individuals: A Review
Abstract: HIV is the chronic viral infection documented worldwide. HIV virus infects and destroys helper T cells (CD4) leading to a number of immunological deficiencies among which Hepatitis-C Virus (HCV) and Tuberculosis (TB) are the major. HCV is a RNA virus that infects the liver leading to cirrhosis, hepatocellular carcinoma and is a leading cause of deaths in HIV/HCV co-infected patients. Tuberculosis, the most common opportunistic infection in HIV positive patients, …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 6, Issue 3, 2016 · pp. 38–41 Read article
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Cartridge-Based Nucleic Acid Amplification for Rapid Tuberculosis Diagnosis
Abstract: In terms of public health, tuberculosis continues to have a significant impact on people's lives. The process of determining the underlying cause of a sickness or condition in a patient is known as clinical diagnosis. It entails the use of numerous diagnostic methods, including physical examinations, laboratory testing, and imaging procedures for medical purposes. Smear microscopy, which are frequently utilized, have poor sensitivity and lengthy turnaround times, respectively. An innovative, …
Published in International Journal of Pathogens · Vol. 1, Issue 1, 2024 · pp. 43–48 Read article
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A Study to Evaluate Nurse Led Intervention Regarding Home Care Management Among Tuberculosis Patients Attending Chest and TB OPD at PGIMS Rohtak
Abstract: Introduction: Tuberculosis is an infectious bacterial pathogen caused by the bacillus called Mycobacteriumtuberculosis, an acid-fast rode shaped bacillus 0.8–5 μm in length and 0.2–0.6 μm in thickness. Tuberculosis (TB) primarily impacts the lungs (pulmonary TB), but it can also affect other parts of the body (extra-pulmonary TB). It spreads through the air and causes damage to the lungs and various other organs. TB is a significant public health issue in …
Published in International Journal of Emergency and Trauma Nursing and Practices · Vol. 3, Issue 1, 2025 · pp. 31–36 Read article