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20 articles for “Transdermal delivery”
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Recent Advances & Prospects of Transferosomes for Transdermal Delivery: Trends in Drug Delivery
Abstract: There have been several non-invasive administrations that have emerged recently to replace conventional needle injections. With its minimal rejection rate, remarkable ease of administration, and remarkable patient comfort and perseverance, the transdermal drug delivery system (TDDS) is the most attractive of them all. The skincare industry, which includes cosmetics, may also find use for TDDS in addition to the pharmaceutical industry. As this strategy mainly entails local drug administration, it …
Published in Trends in Drug Delivery · Vol. 11, Issue 3, 2024 · pp. 01–21 Read article
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Evaluation of Polysaccharide-Based Membranes for Transdermal Drug Delivery in Chronic Pain Management
Abstract: In order to improve treatment effectiveness and patient compliance, chronic pain management is still a major challenge in modern healthcare, requiring creative medication delivery methods. The potential of polysaccharide-based membranes for transdermal drug delivery is assessed in this work, with particular attention to chitosan, alginate, and hydroxypropyl methylcellulose (HPMC). Fourier-transform infrared spectroscopy (FTIR) and scanning electron microscopy (SEM) were two characterization techniques used to assess the membranes' physical and chemical …
Published in International Journal of Membranes · Vol. 1, Issue 2, 2024 · pp. 28–38 Read article
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Microneedles: A Modern Breakthrough in Drug Delivery Systems
Abstract: Microneedles (MNs) represent a revolutionary and transformative advancement in the realm of transdermal drug delivery systems, which are designed to facilitate the administration of therapeutic agents through the skin. These exceptionally small, micron-scale needles penetrate the stratum corneum, thereby enabling the direct delivery of pharmacological agents into the underlying dermis or the upper epidermis, consequently enhancing bioavailability while simultaneously circumventing the detrimental effects of first-pass metabolism and the degradation that …
Published in Trends in Drug Delivery · Vol. 12, Issue 3, 2025 · pp. 01–07 Read article
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Biodegradable and Natural Fiber-Reinforced Polymer Composites for Advanced Controlled Drug Delivery Systems
Abstract: Polymer-gel forms have gained popularity in medicine as means of medication delivery over the skin. This is so since they enable medications pass the skin more readily. These products allow medicine to be administered without surgery and provide continuous active ingredient supply. They are excellent for long-term therapy for managing conditions that keep resurfacing. From tiny synthetic ones to huge biological ones, polymer gels can store a wide spectrum of …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 271–284 Read article
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Morphine: A Pharmacological Perspective on Its Cancer Pain Management
Abstract: Morphine continues to be a key treatment in managing cancer pain because of its strong pain-relieving effects and established clinical history. Despite the emergence of alternative opioids and pain management therapies, morphine continues to be widely prescribed, particularly in palliative care settings. However, its use has been accompanied by concerns regarding tolerance, dependence, and adverse effects, which complicate long-term administration. This review explores the pharmacological aspects of morphine in cancer …
Published in Trends in Drug Delivery · Vol. 12, Issue 1, 2025 · pp. 1–8 Read article
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Advanced Ointment Formulation: An Insightful Review of Innovation and Efficacy
Abstract: This review provides an in-depth exploration of the evolution of ointment formulations, particularly considering the increasing prevalence of fungal infections and the growing demand for effective antifungal treatments. Traditional ointment formulations, while useful, often face significant challenges, such as inadequate penetration into the skin, poor bioavailability, and undesirable textures that limit their efficacy. As a result, there has been a shift toward more advanced, innovative formulations that aim to address …
Published in Nano Trends – A Journal of Nano Technology & Its Applications · Vol. 27, Issue 1, 2025 · pp. 14–23 Read article
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Effect of Skin Barrier Damage on Absorption and Action of Cosmeceuticals
Abstract: The skin acts as a primary defensive barrier protecting the human body against environmental aggressors, microbial invasion, and chemical exposure. The integrity of the skin barrier, particularly the stratum corneum, plays a crucial role in regulating the permeation of substances applied topically. Cosmeceuticals, a hybrid category between cosmetics and pharmaceuticals, are designed to deliver biologically active ingredients into the skin to exert therapeutic or beneficial effects. However, the condition of …
Published in Recent Trends in Cosmetics · Vol. 3, Issue 2, 2026 · pp. 1–19 Read article
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Formulation and Evaluation of Transdermal Patch to Enhance Treatment of Alopecia
Abstract: The improvement of novel topical sedate conveyance frameworks has picked up noteworthy consideration due to their potential in upgrading the helpful viability and persistent compliance whereas minimizing systemic side impacts. This thinks about centers on the definition and assessment of transdermal patches planned to discharge allicin, the essential naturally dynamic compound determined from garlic (Allium sativum) extricate. Allicin is eminent for its wide range of pharmacological properties, counting antimicrobial, anti-inflammatory, …
Published in Trends in Drug Delivery · Vol. 12, Issue 2, 2025 · pp. 20–33 Read article
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Polymer Chemistry-Driven Approaches for Improved Therapeutic Delivery
Abstract: Polymer chemistry has revolutionized pharmaceutical technology by enabling the development of advanced drug delivery systems with improved precision, stability, and therapeutic outcomes. This review explores the role of polymer design, synthesis, and functionalization in the development of responsive and targeted drug carriers. Emphasis is placed on various types of polymers—biodegradable, synthetic, natural, and stimuli-responsive—and their suitability for drug delivery platforms such as nanoparticles, micelles, hydrogels, dendrimers, and implants. The physicochemical …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 Read article
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Effect of Polymer Crosslinking on Drug Release Kinetics
Abstract: In order to improve treatment effectiveness and minimise adverse effects, polymer-based drug delivery systems are often used to produce regulated and sustained drug release. Polymer crosslinking, which alters the structural, mechanical, and degrading characteristics of the polymer matrix, is one of the key elements affecting drug release kinetics. The porosity, swelling behaviour, and rate of degradation of the polymer are all impacted by the crosslinking process, which may be accomplished …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 636–647 Read article
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A Brief Review on Herbal Excipients
Abstract: Natural or herbal excipients are significantly more advantageous than their synthetic equivalents because they are readily available, non-toxic, and less expensive. The pharmaceutical industries are becoming more interested in using these herbal excipients – mainly polymers of natural origin – in formulation development because of growing knowledge of them. The purpose of this study is to provide light on the possibility of using natural excipients, which are biocompatible and able …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 12, Issue 2, 2025 · pp. 5–14 Read article
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Polymeric Drug Delivery Systems for Veterinary Applications
Abstract: Drug delivery systems play a pivotal role in veterinary medicine, facilitating the effective administration of medications to animals for therapeutic purposes. This review provides a comprehensive overview of the definition, importance, and recent advancements in drug delivery systems for veterinary applications. Beginning with an introduction to the challenges inherent in veterinary drug delivery, the review outlines the significance of innovative delivery systems in optimizing drug efficacy, enhancing patient compliance, and …
Published in Research and Reviews : Journal of Veterinary Science and Technology · Vol. 13, Issue 1, 2024 · pp. 19–34 Read article
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Polymeric Materials in Drug Delivery: Applications in Topical Formulations
Abstract: Polymeric materials play a crucial role in modern drug delivery systems, particularly in topical formulations. These materials enhance drug stability, control release rates, and improve bioavailability, making them essential components in pharmaceutical advancements. Polymers such as chitosan, hydrogels, and emulsifying agents are widely utilized in immediate-release topical formulations, where they contribute to improving therapeutic efficacy by ensuring uniform drug distribution, increased solubility, and enhanced skin penetration. The integration of polymer-based …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 · pp. 34–41 Read article
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3D-Printed Polymeric Drug Delivery Systems for Personalized Medicine
Abstract: Personalized medicine has revolutionized healthcare by tailoring treatments to individual patient needs. Among the emerging technologies, 3D printing has demonstrated immense potential in fabricating polymeric drug delivery systems with precise control over drug release, dosage, and bioavailability. These systems offer customized therapeutic solutions, improving efficacy while reducing adverse effects. This paper provides an overview of 3D-printed polymeric drug delivery systems, discussing the types of polymers used, fabrication techniques, applications in …
Published in Journal of Polymer & Composites · Vol. 13, Issue 4, 2025 · pp. 313–325 Read article
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Microneedles: An Innovative Drug Delivery System
Abstract: Microneedles represent a groundbreaking innovation in drug delivery systems, offering a transformative alternative to conventional hypodermic needles and transdermal patches. This advanced technology combines the precision and efficacy of needle-based delivery with the convenience and pain-free nature of patches, creating a minimally invasive platform that addresses many limitations of traditional drug administration. Microneedles are designed to penetrate the stratum corneum – the skin’s outermost layer – without reaching pain-sensitive nerves …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 2, 2025 · pp. 60–67 Read article
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Harnessing Polymer Chemistry for Pharmaceutical Technology
Abstract: Polymer chemistry has emerged as a cornerstone of modern pharmaceutical technology, offering unprecedented control over drug formulation, delivery, and therapeutic performance. This review highlights the pivotal role of polymers—both synthetic and natural—in revolutionizing drug delivery systems across various routes, including oral, parenteral, transdermal, ocular, nasal, and pulmonary administration. Special emphasis is placed on the structural and functional versatility of polymers, which allows for tailored drug release profiles, enhanced bioavailability, and …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 1–6 Read article
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Polymer Chemistry in Sustained-Release Herbal Composites: Designing a Stable Euphorbia tithymaloides Topical System with Phospholipid and Polymer Matrices
Abstract: Polymer chemistry enables the stabilization and sustained release of herbal actives, critical for topical therapeutic applications. This study explores a novel process for preparing a stable, sustained-release topical composition of Euphorbia tithymaloides, leveraging polymer-based systems. Ethanolic extract (50 mg) of the plant, rich in unstable sugar moieties (e.g., D-ribose) and sterols (e.g., stigmasterol), is encapsulated within a phospholipid matrix of phosphatidylcholine (50–100 mg) and cholesterol (50–100 mg). This lipid-polymer complex, …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 165–171 Read article
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Vaccines Through Time: Conventional Foundations and Next-Gen Innovations–Part 1
Abstract: Vaccination serves as a critical pillar of global public health, markedly decreasing infection rates and associated mortality. Traditional vaccine platforms such as live attenuated, inactivated, toxoid, and subunit vaccines have demonstrated effectiveness against pathogens like Mycobacterium tuberculosis and Plasmodium spp., yet they are constrained by antigenic variability, limited immune persistence, and complex production processes. Breakthroughs in synthetic biology, structural antigen design, and computational vaccinology have driven the development of advanced …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 16, Issue 1, 2026 · pp. 53–70 Read article
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Comprehensive Review on Pulsatile Drug Delivery System: Hybrid Approaches
Abstract: Pulsatile drug delivery systems (PDDS) represent a groundbreaking approach in pharmaceutical technology, allowing for controlled, targeted, and programmable drug release that aligns with circadian rhythms or caters to time-sensitive therapeutic requirements. Although traditional pulsatile systems have shown considerable clinical promise, their effectiveness is frequently compromised by physiological variations such as gastrointestinal transit times, changes in pH, and enzymatic activity. To tackle these obstacles, hybrid PDDS have been developed by combining …
Published in Trends in Drug Delivery · Vol. 13, Issue 1, 2026 · pp. 18–31 Read article
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Cosmetic Topical Formulations: Design Strategies, Skin Interaction Mechanisms, Clinical–Cosmetic Applications, and Emerging Trends
Abstract: Cosmetic topical products are central to modern skin care, as they deliver active ingredients directly to the skin surface and upper layers to improve appearance, texture, and function. By acting locally on the epidermis and adnexal structures, these preparations help manage dryness, photoaging, pigmentation, acne, and sensitive-skin conditions while minimizing systemic exposure. A wide range of dosage forms—creams, lotions, gels, ointments, serums, sprays, and transdermal-inspired cosmetic patches—are engineered to modulate …
Published in Recent Trends in Cosmetics · Vol. 3, Issue 2, 2026 · pp. 39–47 Read article