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28 articles for “S. typhi”
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Molecular Docking and Pharmacokinetic Profiling of the Phytocompounds of Jatropha curcas as Antagonist for Salmonella typhi
Abstract: Background: Typhoid is an infection caused by the Gram-negative bacterium, Salmonella enterica serovar typhi. The study assessed the potential use of Jatropha curcas as a typhoid fever therapy alternative to traditional medications. The ability to uncover novel drug indications for currently available medications using in silico methods has increased thanks to the wealth of pharmacological and biological knowledge that is available. Objective: In this study, we assessed the potential inhibitory …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 1, Issue 1, 2023 · pp. 67–81 Read article
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PCR identification of blaTEM gene mediated for ESBL drug resistance in Salmonella typhi
Abstract: Objective: The aim of the present study to identify the presence of R-plasmid and detect the blaTEM gene encodes for ampicillin resistance.Materials and Methods: Salmonella typhi organisms isolated from widal positive blood samples and screened by standard screening methods. Antimicrobial susceptibility test by Kirby-Bauer disc diffusion method and MIC by agar dilution method for Ampicillin performed as per Clinical Laboratory Standard Institute (CLSI) guidelines. ESBL detection by phenotypic confirmatory test, …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 6, Issue 2, 2016 · pp. 1–6 Read article
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Detection and Killing of Food Poisoning Salmonella Typhimurium in Cheese by Using Monoclonal Antibody and Nanoparticles Complex
Abstract: Present studies were conducted to test the ability of gold nanoparticles (GNPs) to detect and kill the bacterial contaminated food samples like cheese. The GNPs were prepared in two methods, sample A was purple 72 to 78.3 nm, while sample B was wine-red and the size was 51.5 to 58 nm. The results obtained suggest that the GNPs were synthesized with different particle size. UV-VIS spectroscopy and zeta potential tests …
Published in Research & Reviews : Journal of Food Science & Technology · Vol. 5, Issue 1, 2016 · pp. 1–10 Read article
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Evaluation of Nucleic Acid Amplification Method in Diagnosing Enteric Fever in Children
Abstract: The comparison of three detection methods (Widal test, Typhi dot and Nested PCR) for diagnosis of typhoid fever was done in laboratory where gold standard was either Widal positive or Typhi dot positive or both positive. A nested polymerase chain reaction (PCR) specific for Salmonella enteric serovar typhi was used for the detection of the pathogen in blood samples. Total 52 patients with clinical suspicion of typhoid fever were recruited …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 3, Issue 1, 2013 Read article
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Epidemiology, Risk Factors, And Prevention Of Typhoid Fever In North India: A Regional Perspective
Abstract: Introduction: Typhoid fever, caused by Salmonella enterica serovar Typhi, remains a major public health concern, particularly in low- and middle-income countries. The disease is transmitted through contaminated food and water, leading to significant morbidity and mortality. Understanding its epidemiology, associated risk factors, and preventive measures is essential for effective control and management. This study aims to provide a comprehensive analysis of typhoid fever's prevalence, risk factors, and recommended interventions, with …
Published in Research and Reviews : A Journal of Immunology · Vol. 15, Issue 3, 2025 Read article
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Herbal Frontiers: The Role of Alternative Remedies in Combating Typhoid Fevers
Abstract: Typhoid fever, caused by Salmonella typhi, remains a major health challenge, particularly in developing regions where sanitation and healthcare resources are limited. With an estimated global incidence of 17 million cases annually, the disease poses a significant public health burden. The growing resistance to conventional antibiotics, such as fluoroquinolones and third-generation cephalosporins, exacerbates treatment challenges. This has spurred interest in alternative remedies, including herbal and homeopathic treatments.Herbal medicine offers a …
Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 1, 2025 Read article
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Typhoid Fever: Etiology, Clinical Manifestations, Diagnosis, and Management
Abstract: Typhoid fever is a systemic and potentially life-threatening infectious disease caused by Salmonella enterica serotype Typhi, which primarily spreads through the fecal-oral route via ingestion of contaminated food and water. It continues to be a major global public health concern, particularly in developing and low-resource countries where poor sanitation, inadequate personal hygiene, and unsafe water supplies prevail. The disease is characterized by prolonged high-grade fever, abdominal discomfort, headache, loss of …
Published in Recent Trends in Infectious Diseases · Vol. 3, Issue 1, 2026 · pp. 1–4 Read article
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Screening and Biochemical Identification of Diarrhea Causing Bacteria from Food Sample
Abstract: In adults, diarrhea is a very frequent symptom. Sick person who has experienced diarrhea for betterm than infrequent daytimes or who have concomitant agitation, prostration, or rectal bleeding are additional possible to seek medical help. The majority of patients may be treated as outpatients with success. Gastroenteritis, on the other hand, is responsible for about 450,000 hospital admissions each year (1.5 percent of adult hospitalizations). Regular diarrhea (fluid stools for …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 12, Issue 3, 2022 · pp. 19–29 Read article
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The Ames Test in Twenty-first Century
Abstract: Since the 19th century, industrial development has increased exposure to mutagens and possible carcinogens. In order to avoid these health risks, several techniques have been developed to recognize genotoxins. In the 1970s, Dr. Bruce Ames and colleagues, studying the histidine operon of Salmonella typhimurium, observed that histidine (−) auxotroph mutants were reverted to histidine (+) upon exposure to a mutagen. The researchers further observed that known carcinogens were mutagenic to …
Published in Research and Reviews: A Journal of Toxicology · Vol. 2, Issue 1, 2012 · pp. 23–37 Read article
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In Vitro Screening of Antibacterial Potentiality of Some Important Flowers’ Extracts Against Some Pathogenic Bacteria
Abstract: Normal 0 false false false EN-US X-NONE X-NONE MicrosoftInternetExplorer4 The present investigation was carried out to screen and evaluate the antibacterial activities of different flowers, namely, Calendula officinalis, Rosa damacena, Hibiscus rosa-sinensis, Datura stramonium, Bougainvillea stabilis, and Vinca rosea. These flowers were screened for potential antibacterial activity against some important bacterial Gram negative and Gram positive bacteria strains, namely Escherichia coli, Salmonella typhi, Staphylococcus aureus, and E. faecalis. Dried leaf …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 1, Issue 3, 2011 Read article
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Chromosomal Aberration and Mutagenicity Toxicological Studies of Beta-Sitosterol Isolated from Ocimum gratissimum (Lamiaceae)
Abstract: Ocimum gratissimum is an important medicinal plant belonging to the Lamiaceae family. Ocimum gratissimum is a small erect or straggling tree or large, woody, climbing shrub found almost throughout India including Andaman and Nicobar Islands. Stem have been used in antifertility treatment in the indigenous system of medicine, and further clinical tests substantiated their efficacy. The root bark contains diketones, fatty matter, rubber, dulcitol, Beta-sitosterol, phlobatannin and glycosidal tannins. Stem …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 4, Issue 2, 2017 · pp. 1–6 Read article
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Assessment of In Vitro Probiotic Potential of Lactic Acid Bacteria
Abstract: AbstractProbiotic potential of fermented milks isolates Lactobacillus rhamnosus NS6, Streptococcus thermophilus MD2 and Streptococcus thermophilus MD8 were carried out by performing various in vitro tests. MD2 and MD8 were able to survive at pH 2 and 3 in broth, while NS6 was found to be pH sensitive and could not survive at pH 2, but maintained its viability at 3 pH. All the cultures were able to survive at 0.5 …
Published in Research and Reviews : Journal of Dairy Science and Technology · Vol. 5, Issue 1, 2016 · pp. 17–30 Read article
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Evaluating the Antibacterial Perspective of Cuminaldehyde, a component of Cuminum cyminum Against Some Common Human Intestinal Pathogens
Abstract: The increasing failures of chemotherapeutics and antibiotic resistance exhibited by pathogenic microbial infectious agents have led to the study on Cuminum cyminum (Family: Apiaceae) for its potential antimicrobial activity against common intestinal pathogens. Cuminaldehyde is considered as the principal component and is believed to be the chief chemical constituent for exhibiting bactericidal activity. The present investigation involved exploration of antibacterial property of cuminaldehyde against some common human intestinal pathogens such …
Published in Research & Reviews : Journal of Herbal Science · Vol. 7, Issue 2, 2018 · pp. 10–12 Read article
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Inhibition of Growth of Selected Bacterial Species Through the Use of Methanolic Maceratives of Black Soldier Fly Pre-Pupae
Abstract: The attempt is dealing with of analysis of effect of maceratives of prepupal stages of black soldier fly (BSF) (Hermetia illuncens L.) in methanol on the inhibition of the growth of selected bacterial species. The bacterial species used for the study include: Salmonella typhimurium (L.); Escherichia coli (L.); Pseudomonas aeruginosa (L.); Bacillus cereus (L); Bacillus subtilis (L); Streptococcus cremoris (L); Streptococcus faecalis (L); Staphylococcus aureus (L); Klebsiella pneumoniae (L); Salmonella …
Published in Journal of Catalyst & Catalysis · Vol. 8, Issue 2, 2021 · pp. 30–44 Read article
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A Single-domain Antibody Cross-reacts with Lipopolysaccharide from Diverse Gram-negative Bacteria
Abstract: Gram-negative bacterial sepsis and endotoxemia are the leading causes of morbidity and mortality in animals and humans worldwide, and attempts have continued to design rational therapies. Endotoxin/lipopolysaccharide (LPS)-neutralizing polyclonal and monoclonal antibodies have been produced, but are not free from problems. Single-domain antibodies (dAbs), constructed from the camelid and the shark ‘heavy chain antibodies’ by phage display technology possess favorable features for in vivo applications. The objective of this study …
Published in Research and Reviews : A Journal of Immunology · Vol. 6, Issue 2, 2016 · pp. 29–37 Read article
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Fungal Synthesis of Silver Nanoparticles by an Indigenous Species of Fusarium, Its Antibacterial Activity and Efficacy as Antibiotic Enhancer
Abstract: The investigations on green combination strategies and on its potential applications for the humanity are on incline for more than 10 decades in the field of bioscience. The research on silver nanoparticles by the use of microorganisms is very much popular these days as it is very easily available source for their synthesis. In the present work, an indigenous Fusarium species isolated from soil sample has been used for the …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 8, Issue 3, 2018 · pp. 10–18 Read article
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Assessment of antibody titer distribution against Salmonella enterica among suspected enteric fever patients.
Abstract: Typhoid fever is a global health problem, causing millions of deaths each year. It is an endemic problem in many developing countries including Nepal. Development of exceptional mechanisms for persistence in its host supports its survival and transmission. However, due to a lack of sophisticated labs and adequate funds, difficulties in the estimation of worldwide impact are often encountered. The Widal test is a diagnostic technique extensively employed to identify …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 13, Issue 2, 2023 · pp. 26–33 Read article
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Combined Antibacterial Effects of Honeybee (Apis mellifera) and Garlic (Allium sativum) Extracts against Standard and Clinical Pathogenic Bacteria
Abstract: Normal 0 false false false EN-US X-NONE X-NONE Among natural antimicrobial substances, honey and garlic were widely used and investigated separately. But their synergistic antibacterial effect was not studied. The objective of this study was to investigate synergistic antimicrobial effect of combination of honey and garlic against pathogenic bacteria. The antimicrobial activity of mixture of honey and garlic, honey and garlic extract alone against Salmonella NCTC 8385, Listeria monocytogenes (ATCC …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 3, Issue 1, 2013 Read article
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Cynodon Dactylon: Antimicrobial Potential of Crude Extract as Valuable Medicinal Plant
Abstract: Cynodon dactylon (Poacae) is a well known traditional plant used as a folk remedy in treatment of many symptoms and diseases like cramps, measles, tumors, wounds, warts, fever and rheumatic affections. In this study, the antimicrobial activity of the plant crude extract from three different extraction (hot and cold aqueous extraction, methanol extraction) was investigated against some of the gram positive bacteria (Staphylococcus epidermidis, Bacillus cereus) and gram negative bacteria …
Published in OmniScience: A Multi-disciplinary Journal · Vol. 4, Issue 3, 2014 · pp. 6–11 Read article
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Multiplex PCR Assay for Rapid Detection of Different Strains of Escherichia coli Associated with Fish and Fishery Products
Abstract: A multiplex PCR (MPCR) assay was developed for the detection of Escherichia coli using selected primers designated on the species- and strains-specific genes such as hlyA, LT1 and phoA. The internal regions amplified were having a product size of 165, 275, and 903 bp, respectively. This MPCR assay had a sensitivity of detecting four cells of E. coli within 10 h in artificially contaminated shrimp tissue homogenate. The MPCR assay …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 4, Issue 3, 2014 · pp. 1–9 Read article