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675 articles for “Novel”
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Post Covid-Sequela: Novel-Inception of DM: A Review
Abstract: As patients recovers from COVID 19 pandemic, a subset of the covid patients experienced a post covid condition with long term symptoms, few weeks after their discharge or recovery from the (SARS-CoV-2) infection. Hence, we tried to prove the hypothesis whether diabetes mellites is an afresh possible sequala of covid infection by systematically evaluating the consistently changing glucose level of the post covid patients. The databases PubMed and Google Scholar …
Published in Research and Reviews : A Journal of Immunology · Vol. 16, Issue 2, 2026 Read article
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Pharmacophore mapping, 3D QSAR, docking, and ADME prediction studies of novel Benzothiazinone derivatives
Abstract: Background Tuberculosis is a major public health concern worldwide which is caused by Mycobacterium tuberculosis. DprE1 (Decaprenyl Phosphoryl Ribose 2’- Epimerase) is the most challenging target for development of novel anti- tubercular agents because it is a small protein and located into cytoplasmic membrane. So, novel anti-TB drugs did not bound effectively with it. DprE1 catalyzes the oxidation of the 2’ hydroxyl group of DPR (Decaprenyl Phosphoryl D- Ribose) …
Published in International Journal of Antibiotics · Vol. 1, Issue 1, 2024 · pp. 59–82 Read article
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Unlocking Novel Drug Targets and Therapeutic Advancements Against RNA Viruses: Insights from HMPV and SARS-CoV-2
Abstract: Re-emerging RNA viruses pose a significant epidemiological welfare threat due to their high mutation rates, potential for zoonotic transmission, and capacity to cause widespread outbreaks such as Human Metapneumovirus (HMPV), Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), Influenza, etc. The rapid evolution and re-emergence of these viruses necessitate the development of novel drug targets and therapeutic strategies to combat existing and future outbreaks. This study focuses on structural as well …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 15, Issue 3, 2025 · pp. 54–86 Read article
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A Novel Hybrid Link Prediction Algorithm for E-Commerce Recommender System Based upon Common Neighbor and Resource Allocation Methods
Abstract: Link prediction is a challenging task in recommender systems, as it requires the ability to accurately predict future links between users and items. In this study, we propose a novel hybrid link prediction algorithm for e-commerce recommender systems that combines the common neighbor and resource allocation methods. The common neighbor method is a straightforward and intuitive algorithm that calculates the number of shared neighbors between two nodes. The intuition is …
Published in International Journal of Data Structure Studies · Vol. 1, Issue 1, 2023 · pp. 12–17 Read article
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Recent Technological Advancements for Novel and Sustainable Packaging of Dairy Food Products
Abstract: Food packaging is crucial for protecting products, ensuring safety, and facilitating consumption. Important phases comprise manufacturing, wrapping, delivery, and preservation. The primary goal of food packaging is to maintain the quality of products throughout this process. Packaging fulfills multiple functions, including storing items, shielding them, offering convenience, and conveying messages. The packaging process is crucial in preserving the quality of food products, particularly dairy items, which are susceptible to biological, …
Published in Research and Reviews : Journal of Dairy Science and Technology · Vol. 13, Issue 1, 2024 · pp. 38–43 Read article
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The Dual Crisis: Antibiotic Resistance and the Discovery Void – A Review of Novel Therapeutic Strategies and Non-Traditional Approaches
Abstract: The global rise of antimicrobial resistance (AMR) has emerged as one of the most critical public health challenges of the 21st century, threatening to undermine decades of therapeutic success and rendering conventional antibiotic regimens increasingly ineffective. Parallel to the escalating resistance rates is a profound “discovery void,” characterised by a steep decline in the development of new antibiotic classes since the late 20th century. Together, these two interconnected crises create …
Published in International Journal of Antibiotics · Vol. 3, Issue 1, 2026 · pp. 47–65 Read article
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A Novel Direct Weighted Deviation (DWD) Method for Agricultural Enterprise Selection: A Case Study of Namakkal District, Tamil Nadu
Abstract: The study proposes a novel Direct Weighted Deviation (DWD) method for Multi-Criteria Decision Making (MCDM) by eliminating normalization, distance metrics, and pairwise comparisons. DWD is thereafter used to evaluate and select ten rainfed agricultural enterprises against ten generic and context-specific viability criteria in Namakkal District, Tamil Nadu, a water-scarce region in India. Subsequently, other methods (AHP, SAW, WPM, and TOPSIS) are used to obtain a comparative second opinion and validate …
Published in International Journal of Industrial and Product Design Engineering · Vol. 4, Issue 1, 2026 · pp. 1–7 Read article
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DMARDs, Biologic Agents and Novel Experimental Strategies in The Treatment of Rheumatoid Arthritis
Abstract: An inflammatory and autoimmune disease, rheumatoid arthritis (RA) causes severe pain and inflammation in affected areas of the body. According to the report, there is no known cure for RA. Therefore, reducing discomfort and halting future harm must be the goals of present therapy. For the purpose of prevention and to reduce disease activity in RA patients, significant success has been achieved with the continued development of disease-modifying antirheumatic drugs …
Published in Emerging Trends in Personalized Medicines · Vol. 1, Issue 1, 2024 · pp. 14–24 Read article
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A Novel and Efficient Transmission System for Harnessing Hydrokinetic Power from Ocean Currents
Abstract: This paper presents the design principles of a novel power transmission system for an indigenous device known as a “Hydro Vortex Power Generator” that harnesses the power of vortices from low-velocity streams of water. The flow-induced motions of an elastically mounted cylinder that is free to oscillate in the crossflow direction are converted to electricity by the power generator. To convert the oscillations with non-uniform amplitude and frequency to uniform …
Published in Recent Trends in Fluid Mechanics · Vol. 11, Issue 3, 2024 · pp. 14–24 Read article
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A Novel Symmetric Anchor Scoring (SAS) Method for Industrial Location Selection: Application to Electric Vehicle Manufacturing in Tamil Nadu, India
Abstract: This work highlights the city-level detail of decision-making enabled by a new MCDM method Symmetry Anchor Scoring (SAS). Generally conventional methods are good at selecting one best and one worst alternative, but not differentiating among the many strong contenders more likely in practice. Linking MCDM methods to the tradition of decision making, the paper discusses the mathematics and analogical basis of SAS design, provides a visual proof of its ideal …
Published in International Journal of Industrial and Product Design Engineering · Vol. 4, Issue 1, 2026 · pp. 8–19 Read article
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Artificial Neural Network Modelling to Optimize Micro-Drilling Parameters of ECDM of Developed Novel Zn/(Ag+Fe)-MMC
Abstract: Several engineering fields have increased their use of metal matrix composites (MMCs) in the past few years. Due to the increase in composites, the demand for accurate machining has also become important. Specifically, pertaining to biomaterial applications, accuracy factor with desired surface finish is critical. While the near-net shape manufacturing process has advanced, MMCs frequently require post-mould machining to achieve surface quality, and dimensional tolerances. In the present study, a …
Published in Journal of Polymer & Composites · Vol. 11, Issue 1, 2023 · pp. 01–13 Read article
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Development and Evaluation of a Novel Polyaniline/Polyvinyl Alcohol/Silver Nanocomposite for Antibacterial Applications: Synthesis and Characterization
Abstract: A novel nanocomposite made up of polyaniline, polyvinyl alcohol, and silver (PAL/PVA/Ag) was synthesized using the reduction of chemical technique in this study. Aniline was polymerized in situ with ammonium persulfate to create polyaniline (PAL), while Ag+ ions were employed to make an nanoparticle of Ag colloidal solution. The combination of Ag nanoparticles with the PAL/PVA composite resulted in the development of a new nanocomposite. Scanning electron microscopy (SEM) and …
Published in Journal of Polymer & Composites · Vol. 11, Issue 3, 2023 · pp. 39–47 Read article
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Designing a Novel Insider Threat Model for Enhanced Cybersecurity
Abstract: Designing a novel insider threat model is a critical imperative in the realm of cybersecurity. As organizations face an ever-expanding threat landscape, insider threats, whether deliberate or inadvertent, present a formidable challenge to the safeguarding of sensitive data and critical assets. This abstract encapsulates the significance, challenges, and innovations inherent in crafting an effective insider threat model for enhanced cybersecurity. The necessity for novel insider threat models arises from the …
Published in International Journal of Information Security Engineering · Vol. 1, Issue 2, 2023 · pp. 24–27 Read article
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Development of Novel Materials with Photocatalytic Effect
Abstract: For capturing solar energy and for converting it into electric power, it is utmost essential to design materials that can be used for this purpose. Generally, the materials deployed for converting solar energy into electric energy are sensitive to UV-radiation. If the material used for this purpose are sensitive to visible light, it will be the breakthrough research. It has been a challenge to design materials with novelty of being …
Published in International Journal of Photochemistry and Photochemical Research · Vol. 1, Issue 2, 2023 · pp. 25–39 Read article
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Development of Novel Polymeric Articulating Papers for Enhanced Occlusal Contact Assessment in Dentistry
Abstract: Traditional articulating papers, a mainstay in occlusal analysis, often exhibit limitations in consistency and difficulty with quantitative data analysis. This study explores the development of novel articulating papers utilizing advanced polymeric materials. These novel papers aim to address the shortcomings of traditional options by potentially improving: (1) sensitivity and resolution for capturing occlusal contacts, (2) consistency and reproducibility of contact readings, and (3) durability and reusability. The successful development of …
Published in Journal of Polymer & Composites · Vol. 13, Issue 1, 2025 · pp. 1004–1011 Read article
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Preparation, Categorization and Anticancer Study of Novel Bicyclic Compounds from Various Types for (Five and Six)- Membered Ring
Abstract: The characteristics of ring systems change in the presence of functional groups, but in some cases, elements that are considered functional groups can be classified within the same ring. Compounds that contain only carbon and hydrogen are called homogeneous rings, while those that contain other elements are called heterogeneous rings. The atom substituted in place of the carbon atom is referred to as a heteroatom. Generally, the heterocyclic atom is …
Published in Journal of Catalyst & Catalysis · Vol. 12, Issue 3, 2025 · pp. 18–30 Read article
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Synthesis of Novel Hybrid Biocomposites and Experimental Investigation of Mechanical Properties
Abstract: As industries increasingly adopt additive manufacturing, the demand for materials that offer better mechanical properties and functionality is on the rise. The purpose of present research work is to develop a novel hybrid biocomposites for 3D printing applications. The acacia bark, waste powder obtained from wet mahanarayan oil consisting of herbs and other bio filler was added in polylactic acid (PLA) for synthesis of hybrid biocomposites filament by twin screw …
Published in Journal of Polymer & Composites · Vol. 13, Issue 3, 2025 · pp. 1–12 Read article
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A Comprehensive Analysis of Novel Liposomes: Categorization, Approach, Description, and Present Formulations
Abstract: Liposomes have gained attention as a promising drug delivery system, which come with the advantages of biocompatibility, ability to load hydrophilic and hydrophobic drugs, and they can function for targeted drug delivery. In this regard, this paper offers a comprehensive overview on novel liposomes, including classification, formulation strategies, detailed structures, and current pharmaceutical applications. Recent advances in liposomal drug delivery systems includes, new liposomal architectures (i.e. stealth, targeted, stimuli-responsive, hybrid …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 12, Issue 2, 2025 · pp. 15–20 Read article
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Marine Fungi – An Expandable Source for Production of Novel Bioactive Metabolites: A Comprehensive Review
Abstract: The marine environment, representing the largest and most extreme biome on Earth, serves as an unparalleled reservoir of biodiversity. Within this vast ecosystem, marine fungi have emerged as a prolific source of structurally diverse and pharmacologically active secondary metabolites. Dwelling in habitats characterized by extreme high salinity, high hydrostatic pressure, and low temperatures, these microorganisms have evolved unique biochemical and metabolic pathways to synthesize novel compounds, including pyrrole-imidazole alkaloids, cyclic …
Published in International Journal of Fungi · Vol. 3, Issue 1, 2026 · pp. 30–37 Read article
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Computational Molecular Docking Studies to Design Novel 2, 3-Substituted-1-(4-(Piperidin-1-yl) butyl)-1H- indol-5-ol Derivatives for Estrogen Receptor Alfa in AF-2 Domain
Abstract: The present manuscript describes the designing of novel 2, 3-Substituted-1-(4-(Piperidin-1-yl) butyl)- 1H-indol-5-ol derivatives as specific estrogen receptor alfa modulators and their screening by docking studies to determine the binding interaction for the best-fit conformations in the binding site of the ERα receptor. Based on the results of docking studies, the selected ligands reveal the all- important functional groups of the ligands that interact with active amino acid residues in the …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 12, Issue 3, 2025 · pp. 15–49 Read article