Search
7 articles for “Nail fungal infection”
-
"Onychomycosis in the Indian Subcontinent: Clinical, Microbiological and Therapeutic Perspectives,”
Abstract: Onychomycosis is a chronic fungal infection of the nail unit involving the plate, bed, and matrix, accounting for a substantial proportion of nail disorders encountered in dermatology practice worldwide. In South Asia—particularly India, Pakistan, Bangladesh, and Nepal—the burden is amplified by a convergence of climatic, socioeconomic, and healthcare-related factors. Hot and humid environmental conditions, widespread dermatophytosis, occlusive footwear practices, chronic wet work, and limited access to specialized mycological diagnostics contribute …
Published in International Journal of Tropical Medicines · Vol. 3, Issue 2, 2026 Read article
-
Formulation and Evaluation of Transungual Drug Delivery of Fluconazole Using Permeation Enhancers Screened by Hydration of Nail Plate
Abstract: The objective of the work was to formulate nail lacquer containing fluconazole an antifungual drug for the treatment of onychomycosis. Onychomycosis, a common fungal nail infection affects the people. Topical and ungual therapy is limited because of the poor permeation of the drug through nail plate. Film base was prepared using varying concentration of cellulose acetate and ethyl cellulose as polymers. The permeation enhancers were screened by nail plate hydration. …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 8, Issue 3, 2017 · pp. 32–45 Read article
-
Review of the Antifungal Drug Luconazole for the Treatment of Skin Infections
Abstract: Many U.S. researchers are still working on a broad-spectrum imidazole antifungal called Luliconazole to treat dermatophytic skin and nail infections. The in vitro activity of luliconazole against filamentous fungi, including dermatophytes, is among the highest of any antifungal drug tested to date. The unique molecular characteristics of a 10% solution of Luliconazole make it possible for the drug to quickly reach fungicidal concentrations in the nail unit, allowing it to …
Published in Journal of Catalyst & Catalysis · Vol. 9, Issue 2, 2022 · pp. 13–19 Read article
-
NEWEST RESEARCH ON FUNGAL MEDICATIONS
Abstract: Mycosis is a disorder brought on by mould or yeast, commonly known as a fungal infection. Although fungi (plural of fungus) can spread diseases to the mouth, throat, lungs, urinary tract, and many other regions of the body, skin and nails are the most common sites for fungal infections. You will experience various symptoms depending on the kind of fungus infection you have and where it is on your body. …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 13, Issue 2, 2023 · pp. 18–26 Read article
-
Epidemiology and Mycological Analysis of Superficial Mycosis in a Northern Indian Tertiary Care Hospital
Abstract: Background: A fungal infection that affects the outer layer of the skin and its connective tissue, including hair and nails, is called superficial mycosis. These infections are typically caused by fungi, which thrive on keratin, the proteinthat makes up the nails, hair, and skin. A common disease that can affect people of any age, gender, or race is superficial mycosis. Usually, it appears as a streaky red rash that can …
Published in International Journal of Fungi · Vol. 1, Issue 1, 2024 · pp. 1–12 Read article
-
Topical Luliconazole for the Management of Fungal Infections: A Review
Abstract: Luliconazole, an antifungal agent of the imidazole class, possesses a distinctive structure where the imidazole component is fused with the ketene dithioacetate configuration. It exists in its R-enantiomer form, which exhibits greater antifungal efficacy compared to lanoconazole, a compound comprising a racemic blend. Strong action is shown by luliconazole against filamentous fungi, such as dermatophytes. The pharmacokinetic characteristics of dermatophytes, such as Trichophyton rubrum and Microsporum gypseum, help explain why …
Published in Trends in Drug Delivery · Vol. 11, Issue 2, 2024 · pp. 1–6 Read article
-
Clinical Fusariosis in India: Taxonomy, Pathogenesis, and Therapeutic Challenges
Abstract: Fusarium species are emerging opportunistic pathogens in humans, responsible for a wide spectrum of infections ranging from superficial keratitis and onychomycosis to life-threatening disseminated disease in immunocompromised hosts. Historically regarded as plant pathogens and environmental saprophytes, these hyaline moulds have become clinically relevant with the increasing use of intensive chemotherapy, haematopoietic stemcell and solidorgan transplantation, and widespread use of broadspectrum antibiotics and corticosteroids. In India, Fusarium assumes particular importance due …
Published in International Journal of Pathogens · Vol. 3, Issue 2, 2026 Read article