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7 articles for “Maturation inhibitors”
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BVM: A Promising Agent for Future HIV-1 Treatment
Abstract: Normal 0 false false false EN-US X-NONE X-NONE MicrosoftInternetExplorer4 /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-qformat:yes; mso-style-parent:""; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-para-margin:0in; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:minor-fareast; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi;} More than 20 individual and fixed-dose combinations of anti-HIV drugs are available for the treatment of human immunodeficiency virus (HIV) infection. However, owing to the development of …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 2, Issue 1, 2011 · pp. 11–21 Read article
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Immunotherapy Advancements in Cancer Treatment
Abstract: Immuno-oncology has been one of the more exciting developments in the field of cancer treatment since about a century ago, with William B. Coley's work in the late 19th century, which really gave the field its beginnings with "Coley's toxin." In an initial effort that proved unsuccessful, early immunotherapy approaches utilizing bacterial mixtures to induce immune responses against tumors nonetheless laid some groundwork for this field. It wasn't until over …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 3, 2024 · pp. 22–28 Read article
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In Situ Investigation of Hemidesmus indicus Phytocompound Extracts as a Therapeutic Target for Acute Myeloid Leukemia
Abstract: Objective: Acute myeloid leukemia (AML) is an apoptotic condition in the hematopoietic system induced by the differentiation and maturation of stem cells into erythrocytes, and leukemic cell proliferation is suppressed as the PI3K-Akt-mTOR pathway is pharmacologically targeted with certain inhibitors. As a result, in silico molecular docking of compounds against AML receptors, CTMP, was used in computational research on Hemidesmus indicus to uncover therapeutic phytochemicals for AML. Thus, this study …
Published in Research and Reviews : Journal of Computational Biology · Vol. 13, Issue 1, 2024 · pp. 38–53 Read article
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Quorum Sensing and Biofilm Dynamics in Pathogens: An Evolving Frontier in Infectious Disease
Abstract: Bacterial and fungal pathogens rarely act as solitary invaders. Instead, they engage in sophisticated chemical communication known as quorum sensing (QS) to coordinate population-wide behaviours and construct structured, multicellular biofilm communities. These biofilms, composed of extracellular polymeric substances, not only facilitate microbial persistence on biotic and abiotic surfaces but also confer remarkable protection against host immune defenses and antimicrobial therapies. QS systems act as central regulators of biofilm dynamics, orchestrating …
Published in International Journal of Pathogens · Vol. 3, Issue 1, 2026 · pp. 18–23 Read article
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Allelopathic Nature of Cucumis Prophetarum Linn.
Abstract: ABSTRACTCucumis prophetarum Linn. is perennial, monoecious climber, commonly growing weed, belonging to family Cucurbitaceae. The whole plant of C. prophetarum is medicinally important. Plant pacifies vitiated dysentery, diarrheic diseases, flatulene, skin diseases, antivenin and general debility. Dispending medicinally uses, our study has found that this weed is allelopathic in nature. To check the allelopathic activity, C. prophetarum was assessed for the effects of their extracts on the growth of mature …
Published in Research & Reviews : Journal of Botany · Vol. 1, Issue 1, 2012 · pp. 16–21 Read article
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Screening of Allelopathic Activity of Momordica dioica and Mukia maderaspatana
Abstract: ABSTRACTAllelopathy is a chemical process which a plant uses to keep other plants from growing too close or away from it. Allelopathy refers to the chemical inhibition of one species by another. The “inhibitory” chemical releases into the environment where it affects the development and growth of neighboring plants. In the present investigation to check the allelopathic activity, two plants of family Cucurbitaceae were selected, i.e., Momordica dioica Roxb. ex …
Published in Research & Reviews : Journal of Botany · Vol. 1, Issue 3, 2012 · pp. 1–7 Read article
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Microbial Profile and Dynamics of Metata ayib
Abstract: Although metata ayib is widely consumed, there is no scientific report about microbial profile, role of microbes and spices during fermentation. The objective of this study is to investigate microbial profile, role of spices and lactic acid bacteria in metata ayib fermentation. Metata ayib was prepared from ayib and different spices. Ayib without spice and sterilized ayib with spices were used as controls. Samples were taken periodically within four days …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 3, Issue 3, 2013 · pp. 15–21 Read article