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13 articles for “Malondialdehyde”
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Vitamin-Aspirin-Prednisolone Therapy for Miscarriage Associated with Anticardiolipin Antibody: Clinical Study
Abstract: Objective: To find pathogenesis of miscarriage associated with anticardiolipin antibody and to make reasonable therapy for the diseases. Methods: Blood coagulation findings, malondialdehyde volume are evaluated and those variations were observed with Vitamin–Aspirin–Prednisolone therapy. And clinical and laboratory findings, pregnancy outcomes were analyzed and relationship between medicine combined therapy and other factors (ages, attack period of disease, miscarriage times, and body mass index) is observed. Results: In anticardiolipin antibody positive …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 12, Issue 1, 2024 · pp. 37–48 Read article
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Antioxidant Activity in Se-Enriched Edible Mushrooms
Abstract: Mushrooms enriched with essential minerals, such as selenium (Se), are food that compensate for dietary nutrient deficiencies. Extracts from Se-enriched Pleurotusostreatus and Lentinula edodes mushrooms contain active antioxidant compounds, which enhance the immune system. To evaluate whether Se-enrichment changes antioxidant and lipid peroxidation potential, the concentration of total phenolic compounds, antioxidant activity, lipid peroxidation and the total concentration of minerals (Mn, Fe, Cu, Zn, V, Cr, Co, Ni, As, Cd …
Published in Research & Reviews : Journal of Food Science & Technology · Vol. 9, Issue 3, 2020 · pp. 28–34 Read article
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Lipid Peroxidation in Postoperative Cases of Breast Carcinoma (Grade III)
Abstract: Breast cancer represents significant problem in the world. Oxidative modification of lipids is catalyzed by reactive oxygen species (ROS) which is known as lipid peroxidation (LPO); this changes the fluidity, permeability of membrane, cellular metabolic functions and causes derangement. Malondialdehyde (MDA) is a major end product and an index of LPO which crosslinks DNA, protein and nucleotides on the same and opposite strands. There are reports that LPO increased in …
Published in Research and Reviews: A Journal of Health Professions · Vol. 8, Issue 1, 2018 · pp. 16–22 Read article
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Foliar Application of Zinc Nanoparticles Improves Photosynthetic Performance in Wheat Plants
Abstract: The present study investigated the impact of foliar spray of zinc oxide nanoparticles on physiological and biochemical reactions in wheat (Triticum aestivum L.) Foliar spray with zinc oxide nanoparticles at 10 mg/l positively increased pigment content and biomass in comparison to control while a significant reduction in chlorophyll content and biomass accumulation was observed at higher concentration of 1000 mg/l. A study of Chlorophyll a fluorescence parameters at 10 mg/l …
Published in Research and Reviews : A Journal of Biotechnology · pp. 12–23 Read article
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Is Beating Heart Coronary Artery Bypass Graft Surgery Associated with Lesser Oxidative Stress and Inflammatory Response?
Abstract: Cardiac operations using cardiopulmonary bypass have been associated with systemic inflammatory response, increased levels of circulating adhesion molecules, and oxidative stress. This study aims to assess various responses in patients undergoing coronary artery bypass grafting (CABG) with or without Cardiopulmonary bypass (CPB) with respect to time after surgery. Sixty consecutive patients undergoing CABG either by on-pump or off-pump technique were studied. Serum levels of tumor necrosis factor- (TNF- -6 (IL-6), …
Published in Research and Reviews : A Journal of Immunology · Vol. 1, Issue 1-3, 2011 · pp. 16–26 Read article
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Arsenic Induced Oxidative Stress and Its Possible Reversal by Chelation Therapy
Abstract: Arsenic (As) is a metalloid listed in group Va of the periodic chart. It exists in nature in the oxidation states +V (arsenate), +III (arsenite), 0 (arsenic) and −III (arsine). In the aqueous environment inorganic arsenic appears commonly in the oxidation states +V and +III as arsenous acid (As (III)), arsenic acid (As (V)), and their salts. Chronic and acute exposures of arsenic leads to cancer, cardiovascular disease (hypertension and …
Published in Research and Reviews: A Journal of Toxicology · Vol. 2, Issue 2, 2012 · pp. 16–37 Read article
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Molecular Mechanism of Fluoride Induced Oxidative Stress and Its Possible Reversal by Chelation Therapy
Abstract: Fluorine (Fl) a member of the halogen family is the most electronegative and reactive of all the elements of the Periodic table. Chronic and acute exposures of fluoride leads to cardiovascular disease (hypertension and atherosclerosis), neurological disorders, gastrointestinal disturbances, liver disease, renal disease, reproductive effects, other health disorders and also affects the antioxidant system in the body. Furthermore, reactive oxygen species (ROS)-mediated oxidative damage is a common malady in fluoride …
Published in Research and Reviews: A Journal of Toxicology · Vol. 3, Issue 2, 2013 · pp. 7–34 Read article
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Protective Effect of Chloroform Extract of Cyperus Rotundus against DNBS Induced Inflammatory Bowel Disease in Rats
Abstract: The present study was designed to evaluate the effects of Cyperus rotundus on DNBS (Dinitrobenzene sulfonic acid) induced IBD in experimental rats. The experimental protocol (Protocol No. 9012 dated 26th Dec 2009) was approved by Institutional Animal Ethical Committee of Anand Pharmacy College. Colitis was induced with DNBS (180 mg/kg in 50% ethanol) intracolonically in animals on the 11th day of the study. Animals were fasted for 24 h prior …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 4, Issue 3, 2014 · pp. 24–32 Read article
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Anti-Ulcer Activity of Ethanolic Extract of Sesamum indicum Seed on Indomethacin-Induced Ulcer Model and Its Antioxidant Property in Gastro-Protection
Abstract: The present study was intended to investigate and evaluate the antiulcer activity of the ethanol seed extract of Sesamum indicum Linn. using Indomethacin Induced Ulcer in Albino rats and to determine its link between oxidant or antioxidant parameter. The extract of Seamum indicum Linn. was tested on indomethacin induced gastric ulcer in Albino rats. The antiulcer activity of high dose (400 mg/kg) and low dose (200 mg/kg) of ethanolic extract …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 5, Issue 2, 2015 · pp. 18–25 Read article
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Anti-Ulcer Activity of Methanolic Extract of Mucuna Pruriens Seed on Indomethacin Induced Ulcers in Albino Rats
Abstract: The present study was intended to investigate and evaluate the antiulcer activity of the methanol seed extract of Mucuna pruriens using indomethacin induced ulcer in albino rats and to determine its link between oxidant or antioxidant parameter. The extract of Mucuna pruriens was tested on indomethacin induced gastric ulcer in albino rats. The antiulcer activity of high dose (400 mg/kg) and low dose (200 mg/kg) of ethanolic extract of Mucuna …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 5, Issue 2, 2015 · pp. 1–8 Read article
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Antioxidant Property and Stability of an Indigenous Traditional Food Daangar pachadi
Abstract: In South India, a traditional food namely Daangar pachadi is prepared from black gram, cumin and yoghurt and consumed occasionally in certain places of Tamil Nadu, India. Even though several health benefits of yoghurt is proven scientifically, the health benefits of incorporation of black gram and cumin seeds in yoghurt is not yet investigated. In addition, effect of removal of seed coat from black gram on the total phenolic content …
Published in Research & Reviews : Journal of Food Science & Technology · Vol. 6, Issue 3, 2017 · pp. 22–31 Read article
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Eugenol Prevents Sodium Nitrate-induced Altered Antioxidant Status of Spermatozoa: An In Vitro Study
Abstract: Background: High level of nitrate (NO3) induces oxidative stress which affects the male and female reproductive system. In this regard, there is a great concern for the prevention of NO3-induced oxidative stress in the reproductive system by using herbal products. Eugenol is one such natural product found in clove extracted from cloves (Syzygium aromaticum) and is known for its antioxidant, anti-nociceptive, anti-inflammatory, and anti-apoptotic properties. Aim and Objectives: The present …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 12, Issue 2, 2022 · pp. 1–8 Read article
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Anti-ulcer Properties of Methanol Extract and its Solvent Fractions of Stem Bark of Lannea acida on Indomethacin Induced Gastric Ulcer in Albino Rats
Abstract: Lannea acida is use in Nigeria for the treatment of Peptic ulcers. The methanol and its solvent fractions (hexane, ethylacetate and butanol) of the stem bark of Lannea acida were evaluated for antiulcerogenic activity using indomethacin model. The anti-ulcerogenic mechanisms of the plant using the model employed in this study were done by estimation of Superoxide dismutase (SOD), Glutathione (GSH), Catalase (CAT), Vitamins A, C and E, and Malondialdehyde (MDA). …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 11, Issue 3, 2023 · pp. 20–35 Read article