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248 articles for “Inhibitor”
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Mass Spectrometry–Based Phosphoproteomic Markers to Predict Kinase Inhibitor Response in Solid Tumors
Abstract: Mass spectrometry-based phosphoproteomics has emerged as a powerful tool for predicting kinase inhibitor responses in solid tumors, offering direct functional insights into signaling pathways that surpass traditional genomic profiling by capturing dynamic kinase activities and adaptive resistance mechanisms. Technological breakthroughs, including data- independent acquisition (DIA), trapped ion mobility spectrometry (timsTOF), and efficient enrichment methods like TiO2 or IMAC, now enable comprehensive profiling of over 40,000 phosphorylation sites from limited clinical …
Published in International Journal of Cell Biology and Cellular Functions · Vol. 4, Issue 2, 2026 Read article
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Corrosion Testing and Evaluation of Inhibitors Performance
Abstract: Choosing test methods that will analyze specific needs, like film barrier strength that real field settings is essential for the proper evaluation and development of inhibitors. The flowing loop and the bubble test are two examples of the first and second, respectively. Corrosion is measured by gravimetric, electrical noise, alternating-current impedance, potentiodynamic measurement, linear polarization and gravimetric. The inhibitors action can be analyzed in different corrosive environments. Their performance is …
Published in Journal of Materials & Metallurgical Engineering · Vol. 16, Issue 1, 2026 · pp. 82–88 Read article
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6000 inhibitors for aluminum and its alloys
Abstract: 6XXX series of aluminum alloys suffer from severe corrosion in acidic saline medium. These alloys are used for architectural, automobiles, aviation, household appliances, containers and electronic devices. Organic-inorganic sol-gel hybrid coatings are synthesized on these alloys. Rear earth inhibitors consider lanthanum inhibitors to be better than cerium inhibitors. These contexts discuss epoxy-silica-zirconia by sol-gel coatings, paddy residue, colchicines, rare earth coatings and ionic liquid for composites
Published in Journal of Thin Films, Coating Science Technology & Application · Vol. 6, Issue 2, 2019 · pp. 18–25 Read article
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Comparative Evaluation of Hibiscus Cannabinus and Solanum Trilobatum Extracts as Inhibitors for C- Steel Corrosion protection in Acidic Medium
Abstract: This study analyzed the efficacy of various inhibitors in safeguarding carbon steel against corrosion in hydrochloric acid. The compounds that were subjected to testing included Acalypha indica root extract (AIRE), Hibiscus cannabinus (HC), and Solanum trilobatum (ST) leaf extracts. The investigation focused on the inhibitory efficacy through the application of gravimetric and electrochemical impedance methods. GC-MS and FTIR were employed to investigate the features of the inhibitors and co-inhibitors. Tafel …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 555–565 Read article
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Corrosion inhibitors of steel applicable by green but toxics
Abstract: Inhibitors in detergent and alkali based chemicals are used in various media for steels. Toxicity has induced pharmaceutical compounds as better inhibitors to restrict pollutant gases emissions after reaction with alkaline inhibitors. Green in origin inhibitors are toxin free to use with detergents for inhibition of both pollutant gases and corrosion of processing machineries made of metals. Eco-friendly inhibitors have appeared for steel corrosion being embedded in concrete i.e. alkaline …
Published in Journal of Thin Films, Coating Science Technology & Application · Vol. 6, Issue 2, 2019 · pp. 38–47 Read article
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Waste Plants as a Green inhibitor for Reinforced Concrete
Abstract: AbstractIn recent years, the use of inhibitors in producing high performance concrete has increased significantly as a result of chloride and sulfate attacks. The present inhibitors in market are toxic to the environment. Hence, the objective of the present investigation was to study a novel, eco-friendly and a hydrophobic green plant extracts’ inhibitor (rice husks) and study the effects of it on compression strength of reinforced concrete. The inhibitor above …
Published in Recent Trends in Civil Engineering & Technology · Vol. 7, Issue 3, 2017 · pp. 53–58 Read article
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Evaluation of Tectona Grandis Leaf Extract As A Green Corrosion Inhibitor for Aluminium in 1M NaOH
Abstract: A kind of tropical hardwood tree called the Tectona grandis tree that is indigenous to India. The name "teak tree" is another common name for this kind of tree. It is a member of the plant family that is referred to as Lamiaceae. The primary purpose of this research is to investigate whether or not the plant extract has a corrosion-inhibiting quality. In this study, an aqueous extract of Tectona …
Published in Journal of Polymer & Composites · Vol. 2, Issue 2, 2023 · pp. 41–50 Read article
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Practical approach for Type 2 Diabetes: Role of DPP4 Inhibitors
Abstract: Dipeptidyl peptidase-4 inhibitors (DPP-4Is) have become essential in managing type 2 diabetes mellitus (T2DM) due to their ability to enhance incretin hormone activity, which promotes insulin secretion and inhibits glucagon release. These agents effectively lower HbA1c levels by 0.5–1.0%, are weight-neutral, and have a low risk of hypoglycemia, making them suitable for a broad patient population, including the elderly. The antidiabetic market in India is vast. Gliptin as group row …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 2, 2024 · pp. 20–26 Read article
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Review on Computer-Aided Drug Design in RAS Inhibitor Discovery
Abstract: This review explores the utilization of computer-aided drug design (CADD) methodologies in the discovery of inhibitors targeting the RAS pathway, a pivotal signaling cascade implicated in various cancers. Through an extensive examination of computational tools, methodologies, challenges, and recent advancements, this review aims to provide insights into the role of CADD in accelerating RAS inhibitor discovery. The discovery of effective inhibitors targeting the RAS pathway is of paramount importance in …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 11, Issue 3, 2024 · pp. 7–14 Read article
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Inhibitors of steel corrosion in pipelines
Abstract: Traditions of similarity in test methods have evaluated different efficiencies of different inhibitors. Electrostatically adsorbed green organic inhibitors act as mixed type double layer interactions to steel surfaces. Hydro distillation of plant originated oils is good inhibitors to corrosion of steel, achieved from medicinal grounds. Drinking water corrosion responds maximum numbers of ionic variables to deal with additive mechanical variables for studies in corrosion of steel. Intentional injections of HCl …
Published in Journal of Petroleum Engineering & Technology · Vol. 9, Issue 2, 2019 · pp. 17–26 Read article
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Hydroxylated Chalcone Derivatives as Future Aldose Reductase Inhibitors: Discovery through Docking Technique
Abstract: The research endeavors molecular docking assisted exploration of ALR inhibitory perspectives of some B-ring substituted hydroxyl group (A-ring) containing chalcone compounds against human aldose reductase in complex with NADP+ and the inhibitor IDD594 (PDB ID: 1US0) by utilizing the iGEMDOCK (Genetic Evolutionary Method for Molecular Docking) software. The present investigation immensely focused on the human aldose reductase inhibitory perspectives of some hydroxylated chalcone compounds. The inhibition of the enzyme by …
Published in Research and Reviews : Journal of Computational Biology · Vol. 8, Issue 1, 2019 · pp. 8–12 Read article
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Inhibitors for 2000 series from aluminum
Abstract: Corosion inhibitor is traditional procedure to protect under any weather. Use of inhibitors have formed thin coating film as well film having hydrofobic to super hydrophobic properties. Angle of contact for weather chemical is simplest test appeared to depend on stabilization of surface under interest. Inihibitor considerations have appeared from hybrid toxic-nontoxic to purely green inhibitors to reproduce as environmentally friendly usage. Inhibitors applicable during anodization has technical importance from …
Published in Emerging Trends in Chemical Engineering · Vol. 6, Issue 2, 2019 · pp. 28–38 Read article
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Steel inhibitors of gas well steels
Abstract: Corrosion inhibitor is chemical compound or substance that, when added in small concentration to an environment, effectively decreases the corrosion rate. Multiphase oil and gas well flowlines at subsea has studied to corrode by contamination of CO2 gas at different temperature, partial pressure, velocity of flow and properties of scale formed at inner wall. Irrecoverable localized corrosions cause failure of structures those are beyond effects of corrosion inhibitors. Pollution of …
Published in Journal of Catalyst & Catalysis · Vol. 6, Issue 2, 2019 · pp. 23–33 Read article
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Inhibitors of steel corrosion sector
Abstract: Inhibitor application in medium of exposure is to mitigate corrosion of mild steel. In industrial and ambient weather corrosions is either from acidic medium or soil compositions. Most of inhibitors appear to be green in origin i.e. environmentally friendly. These explorations account to prevent usage of toxic and high cost synthetic inhibitors. Comparative behaviors about inhibition efficiency restrain a long list of organic natural inhibitors to that of synthetic inorganic …
Published in Journal of Catalyst & Catalysis · Vol. 6, Issue 2, 2019 · pp. 12–22 Read article
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SGLT2 Inhibitors in Heart Failure and Chronic Kidney Disease: Expanding Therapeutic Horizons beyond Glycemic Control
Abstract: Heart failure (HF) and chronic kidney disease (CKD) are closely related clinical diseases that significantly increase morbidity and death worldwide. The co-occurrence of both conditions is frequently referred to as the "cardio-renal syndrome," in which the failure of one organ hastens the decline of the other. The original purpose of sodium–glucose cotransporter-2 (SGLT2) inhibitors was to treat type 2 diabetic mellitus (T2DM) by reducing blood sugar levels. Nevertheless, new data …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 16, Issue 2, 2026 Read article
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Corrosion inhibitors of steel made implements
Abstract: Corrosion of steel in industrial weather is ever possible mechanism for failure by loss in weight. Of many materials steel forms most suitable property cluster for industrial infrastructure i.e. from ambient weather to acid plants. Therefore steel is to be protected from corrosion by industrial weather, which may be either by alloy formation or paints or coatings similar to paints. Alloy formation from steel with elements those produce surface adhered …
Published in Emerging Trends in Chemical Engineering · Vol. 6, Issue 2, 2019 · pp. 20–27 Read article
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Inhibitors for steel implements
Abstract: Oil and gas industries use corrosion inhibitors made of active inhibitor intermediate, carboxylic acid, demulsifier and surfactant in aromatic solvent, and alcohol. High pressure and high temperature oil well flow lines are made of steel pipes. These pipes are prone to corrosion from gaseous contamination, oil quality, flow rate, developed shear stress of turbulence, pump spar techniques, etc. Carbon dioxide to carbolic acid conversion at below 100oC temperature appears to …
Published in Journal of Catalyst & Catalysis · Vol. 6, Issue 2, 2019 · pp. 1–11 Read article
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Review of Nitrite Inhibitor for Protection of Rebar Corrosion
Abstract: Load bearing concrete structures need steel reinforcement (rebar) strips or rods, which are prone to attack by the corrosive environment inside the concrete due to constant ingress of moisture, pollutant gases and anions (mainly Cl-, SO4- -). One of the means of reducing such type of corrosion is the use of inhibitors. Inhibitors are water soluble but film forming on metals by their selective adsorption on the metal surface. These …
Published in Journal of Materials & Metallurgical Engineering · Vol. 3, Issue 1, 2013 · pp. 42–56 Read article
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5000 Series of Aluminum and Its Alloys Opaque by Inhibitors
Abstract: 5XXX series of alloys are prepared for marine applications. Light weight, strength, low maintenance and inherent tendency to form passivity surfacing have selected these alloys for manufacture of cargo ships. Anti corrosive paints have been traditional protections in these alloys. Workers exposed to chromate residues during sanding of aircraft and recoating have increased risk of cancer to 250,000-fold higher. These paints are hazardous for aquatic life, so eco-friendly corrosion inhibitors …
Published in Journal of Thin Films, Coating Science Technology & Application · Vol. 6, Issue 2, 2019 · pp. 1–8 Read article
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Molebdate as Corrosion Inhibitor for Aluminium 356 In Acidic and Saline Media
Abstract: Corrosion processes are the cause of significant losses in industry. Organic, inorganic, and mixed material inhibitors have all been used to resist corrosion for a long time, but the environmental toxicity of organic corrosion inhibitors has driven a quest for inorganic corrosion inhibitors. The effect of molybdate as a new corrosion inhibitor on the corrosion of aluminium 356 in acidic and saline conditions was investigated using electrochemical and weight loss …
Published in Journal of Thin Films, Coating Science Technology & Application · Vol. 9, Issue 1, 2022 · pp. 39–47 Read article