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10 articles for “Gram negative micro-organism”
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An innovative antibiotic "Abaucin": Instigated by Artificial Intelligence
Abstract: Nosocomial Gram-negative pathogen, Acinetobacter baumannii repeatedly demonstrates multidrug resistance. Discovering novel antibiotics against A. baumannii has proven thought-provoking through conventional screening tactics. Providentially, machine learning approaches allow for the speedy exploration of chemical space, snowballing the probability of determining new antibacterial molecules. In the following research era, a neural network is accomplished with growth reserve dataset and accomplished in silico predictions for structurally unconventional molecules with commotion in divergence to …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 13, Issue 3, 2023 · pp. 29–33 Read article
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Formulation and Evaluation of Transdermal Patch to Enhance Treatment of Alopecia
Abstract: The improvement of novel topical sedate conveyance frameworks has picked up noteworthy consideration due to their potential in upgrading the helpful viability and persistent compliance whereas minimizing systemic side impacts. This thinks about centers on the definition and assessment of transdermal patches planned to discharge allicin, the essential naturally dynamic compound determined from garlic (Allium sativum) extricate. Allicin is eminent for its wide range of pharmacological properties, counting antimicrobial, anti-inflammatory, …
Published in Trends in Drug Delivery · Vol. 12, Issue 2, 2025 · pp. 20–33 Read article
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A Screening Study on Occurrence and Distribution of Urinary Tract Infections Among Suspected Cases (Pyuria, With or Without Symptoms) During Pregnancy
Abstract: Background: Urinary tract infection is one of the most frequently seen medical complications in pregnancy. Methods: Ethical approval was granted for this research. The study employed a time-bound prospective design; total pregnant women (900) were categorized into those suspected of having UTI (pyuria, with or without symptoms) and those not suspected. Asymptomatic bacteriuria is diagnosed through a urine specimen with an appropriate microscopic examination, followed by culture. Results: The occurrence …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 13, Issue 3, 2024 · pp. 13–20 Read article
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Production, Characterization and Toxicological Evaluation of Eco-Friendly Flavolipid Biosurfactant
Abstract: At present majority of surfactants are chemically synthesized. Nevertheless, in recent years, much attention has been directed towards biosurfactants due to their broad range of functional properties, there are cheaper as they can be produced from alternative sources. They have applications in the fields, such as: oil recovery process, as an additive in food processing industry, pharmaceuticals preparations, energy saving technologies etc. As they are being microbial derivatives, it is …
Published in Research and Reviews: A Journal of Toxicology · Vol. 4, Issue 1, 2014 · pp. 16–21 Read article
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Isolation and Identification of Bacteria Causing Chronic Suppurative Otitis Media and Its Antibiogram
Abstract: Background: Chronic Suppurative Otitis Media (CSOM) is defined as chronic inflammation of middle ear and mastoid cavity, which presents with recurrent ear discharge or otorrhoea through a tympanic perforation. According to WHO, the prevalence of CSOM in India is more than 4% and it falls among those countries where urgent attention is needed. It can be caused by various bacteria, fungus and viruses. Bacterial origin of CSOM is more common …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 9, Issue 3, 2019 · pp. 1–5 Read article
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Encapsulation of Karela Extract in Polymer Nanoparticles
Abstract: Karela (Momordica charantia) fruit extract possesses promising antibacterial properties. However, its direct application can be limited by factors like degradation and uncontrolled release. This study explores the encapsulation of Karela extract within biocompatible and biodegradable polymeric nanoparticles as a potential strategy to enhance its efficacy. The research investigates the development of nanoparticle systems using various polymers and their impact on the stability, controlled release, and antibacterial activity of the encapsulated …
Published in Journal of Polymer & Composites · Vol. 13, Issue 1, 2025 · pp. 864–867 Read article
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The Predatory Bacteria, Bdellovibrio and Like Organisms (BALOs): An Emerging Savior for Human Welfare
Abstract: Bdellovibrio and like organisms (BALOs) are capable of killing other Gram negative pathogenic and non-pathogenic bacteria dwelling in a diverse environmental niches such as soil, freshwater and ocean. The predatory nature of BALOs can be a viable alternative to conventional use of antibiotics to treat ocular, periodontal, respiratory and fish pathogen infections since the incessant use develops resistance against them. Unique property such as potential to survive in ecologically hazardous …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 8, Issue 3, 2018 · pp. 19–33 Read article
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Identification of ESBL producing Escherichia coli from Urine Samples at Tertiary Care Hospital in Jhalawar
Abstract: Introduction: Antibiotic resistance (ABR) is a serious worldwide threat to public health due to the emergence of multidrug resistant bacteria and is considered as a great problem in the treatment of bacterial infections both in hospital as well as community settings. Extended Spectrum Beta-Lactamase (ESBL) producing strains have emerged as a significant challenge to counter with present antibiotics. Aims: Our study was aimed to know the prevalence of ESBL producing …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 7, Issue 3, 2017 · pp. 38–45 Read article
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Ventilator Associated Pneumonia: Prevalence of Bacteria and their Antibiogram in Tertiary Care Centre, Kota, Rajasthan, India
Abstract: Background: Mechanical ventilation is a life-saving procedure, but it is associated with a high risk of acquiring respiratory infections. Hence to prevent it and initiate empirical antimicrobial therapy, knowledge of microbial profile and their local antimicrobial sensitivity pattern are essential. The study aimed to investigate the role of endotracheal aspirate (ETA) surveillance cultures in identifying the aetiology of VAP earlier. Methods: A prospective study was carried out over a period …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 11, Issue 1, 2021 · pp. 30–34 Read article
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Screening and Characterisation of Antibacterial Actinomycetes Isolated From Earthworm
Abstract: The actinomycetes are considered to be the most potent source for the production of secondary metabolites, antibiotics and other bioactive compounds. The present study dealt with the isolation of the actinomycetes from the earthworm, Eisenia fetida. The actinomycetes were identified using slide culture technique and various biochemical tests. The isolates (S1 and S2) showed activity against Gram positive and Gram negative bacteria in primary screening by perpendicular streak method. In …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 9, Issue 1, 2019 · pp. 77–84 Read article