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264 articles for “ER”
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Molecular Docking of Abroma augusta Phytocompounds Against Estrogen Receptor Alpha (Er-Α) for the Treatment of Menstrual Disorders
Abstract: Menstrual disorders, including dysmenorrhea (painful menstruation), amenorrhea (absence of menstruation), and irregular menstrual cycles, significantly impact women’s reproductive health and overall well-being. These conditions often arise from hormonal imbalances, inflammation, and uterine dysfunction, necessitating effective therapeutic interventions. Current treatments, such as hormonal therapies (oral contraceptives, progestin-only pills), NSAIDs, and surgical procedures (endometrial ablation, hysterectomy), provide relief but often target symptoms rather than addressing the underlying causes. Consequently, there is a …
Published in International Journal of Molecular Biotechnological Research · Vol. 3, Issue 2, 2025 · pp. 1–12 Read article
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A Role of Ergonomics in Advanced Manufacturing Systems: A Harmonious Blend of Human and Machine
Abstract: The integration of human and machine elements in advanced manufacturing systems (AMS) necessitates a careful consideration of ergonomic principles to ensure the well-being and performance of the workforce. This paper explores the critical role of ergonomics in AMS, focusing on physical, cognitive, and organizational aspects. By optimizing the interaction between humans and technology, ergonomics aims to reduce musculoskeletal disorders, improve worker satisfaction, and enhance overall system efficiency. The paper delves …
Published in International Journal of Manufacturing and Production Engineering · Vol. 3, Issue 1, 2025 · pp. 1–7 Read article
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Assessment of Soil Erosion Impacts at the Panchhari Sub-district of Chittagong Hill Tracts in Bangladesh Using Remote Sensing and GIS Techniques Based on RUSLE Model
Abstract: Soil erosion has been identified as a significant issue around the world. It is often exacerbated due to land deterioration, conversion of agricultural land, and other anthropogenic activities. It negatively impacts soil productivity, water quality deterioration, river and reservoir bed sedimentation, nutrient loss, and sustainability of natural resources. Understanding the controlling factors of soil erosion can help us to identify erosion-prone areas and improve land use management. The novelty of …
Published in International Journal of Climate Conditions · Vol. 1, Issue 2, 2024 · pp. 9–30 Read article
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Spatiotemporal Modeling of Soil Erosion Under Agricultural Expansion in the Amravati Basin, India Using RUSLE–GIS
Abstract: Agricultural expansion and soil erosion are important environmental issues in areas where agriculture is a major source of livelihood. This study analyzes the spatial and temporal patterns of soil erosion in the Amravati Basin of Maharashtra and evaluates the impact of agricultural expansion using the Revised Universal Soil Loss Equation (RUSLE) integrated with Geographic Information System (GIS) techniques. Multi-source data, such as satellite imagery, rainfall records, soil characteristics, and topography …
Published in International Journal of Land · Vol. 3, Issue 1, 2026 · pp. 50–62 Read article
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Evaluation of Antioxidant and Cytotoxic activities of Mycelia Biomass and Culture broth of three Edible Mushrooms, Morchella conica, Hericium erinaceus and Pleurotus florida Grown in Submerged Culture
Abstract: Mycelia biomass of three edible mushrooms namely, Morchella conica, Pleurotus florida and Hericium erinaceus were grown as submerged culture in potato dextrose broth supplemented with yeast extract, potassium dihydrogen orthophosphate and magnesium sulphate. The mycelia biomass was extracted with 70% ethanol and culture broth with ethyl acetate. The solvents were evaporated to dryness at low temperature using a rotary vacuum evaporator and the residues thus obtained were used for the …
Published in International Journal of Fungi · Vol. 1, Issue 1, 2024 · pp. 37–50 Read article
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An Analysis of Pronunciation Errors in The Production of Silent Letters of English Language by Secondary School Students in Borno State
Abstract: Perfect pronunciation as one of the effective language skills in communication greatly affects teaching, learning and usage of English as a second language because it enhances transfer of information from source to target. This paper adopted Corder explanation of errors and mistakes which sees them as gaps/deficiencies in learners’ knowledge of a language as theoretical framework and analysed pronunciation errors of the English silent letters by Senior Secondary School students …
Published in Emerging Trends in Languages · Vol. 2, Issue 1, 2025 · pp. 33–39 Read article
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Deciphering the Roles of Estrogen Receptors and 27-Hydroxycholesterol in BC Progression
Abstract: Breast cancer (BC) ranks among the top causes of cancer-related deaths in women worldwide. Many risk factors of BC are linked to estrogen. Experiments of Beatson in 1896 show the role of steroid hormones as major determinant in BC. Action of steroid hormones is mediated by their receptors including Estrogen receptors (ERs). ERs are part of a subfamily of ligand-regulated transcription factors. Their primary role is to translate hormone signals …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 2, Issue 2, 2024 · pp. 18–26 Read article
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Antibiotics – Challenges in our Post-COVID Era
Abstract: Accidental discovery of the antibiotic properties of penicillin marked a watershed moment in healthcare, transforming the landscape of medicine and saving countless lives of injured and infected. Further research and awareness on the advantages of this “miracle drug” resulted in its bulk production in the 1940s, and played a crucial role in saving lives of thousands during World War II. Subsequent discoveries especially broad-spectrum antibiotics paved the way for further …
Published in International Journal of Antibiotics · Vol. 1, Issue 2, 2024 · pp. 1–5 Read article
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Effectiveness of Sensitization Program on Knowledge of School Children Regarding Refractive Errors
Abstract: The human eyes are portals of absorbing divine knowledge from the surrounding world. These two precious pearls need to take proper care throughout to taste life. The eye care starts right from birth onward and becomes keenly required in children's school age as they use these gifts for intense learning. The neglected care in the initial years may trouble them with various visual disorders and disturb their studies too. Well-structured …
Published in Recent Trends in Infectious Diseases · Vol. 1, Issue 1, 2024 · pp. 13–20 Read article
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The Next Era of Solid-State Innovation: Beyond Silicon
Abstract: The semiconductor industry is getting close to the physical and economic boundaries of silicon-based technology. A new era of solid-state innovation is beginning. Beyond Silicon: The Next Era of Solid-State Innovation looks at the materials, device layouts, and manufacturing methods that are about to change the way electronics and energy work. The article talks about improvements in wide- and ultra-wide-bandgap semiconductors, two- dimensional materials, and quantum and neuromorphic systems that …
Published in International Journal of Solid State Innovations & Research · Vol. 3, Issue 2, 2025 · pp. 19–23 Read article
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Vaccination in the Era of Precision Medicine: Tailoring Immunization Strategies for Individual Risk Profiles
Abstract: The introduction of precision medicine has caused a paradigm change in the vaccine landscape. Conventionally, vaccination programmes have been homogeneous, targeting immunity at the population level without taking into consideration the individual differences in immune response and vulnerability to diseases that can be prevented by vaccination. However, a more individualised approach to immunisation has been made possible by current developments in genetics, immunology, and data analytics. Within the context of …
Published in International Journal of Vaccines · Vol. 1, Issue 2, 2024 · pp. 32–47 Read article
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The Next Era of Molecular Biotechnology: Beyond DNA
Abstract: Molecular biotechnology has advanced much beyond conventional DNA manipulation, into a phase characterised by precision, integration, and invention. This article examines the evolving domain of next-generation biotechnological instruments, encompassing gene editing technologies like CRISPR-Cas systems, synthetic biology, and RNA-based medicines. It shows how these new technologies are changing medicine by making treatments more personalised, making farming more productive by using genetically modified crops, and making industrial processes more environmentally friendly …
Published in International Journal of Molecular Biotechnological Research · Vol. 4, Issue 1, 2026 Read article
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Impact of a Nurse-Led Work-Based Intervention on Job Performance and Job Satisfaction Among Nurses in Selected Hospitals in Erode
Abstract: Job satisfaction is a critical aspect of nurses’ professional lives, influencing patient safety, staff morale, productivity, performance, and overall quality of care. Higher levels of job satisfaction have been linked to improved patient outcomes. This study aimed to assess the level of job satisfaction among staff nurses before and after a nurse-led work-based intervention, evaluate the effectiveness of the intervention, and examine the association between posttest job satisfaction scores and …
Published in International Journal of Evidence Based Nursing And Practices · Vol. 4, Issue 1, 2026 · pp. 19–27 Read article
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Impacts of Green Facades in Modern Era
Abstract: Modern architecture was an architectural movement or style centred on cutting-edge construction technologies, particularly the use of reinforced concrete, glass, and steel. The foundational goal of 21st century architecture is to create better structures that are inherently sustainable by utilising better materials and technologies. Facades are the outermost covering of a building which have the maximum interaction with the environment. A wall that is completely or partially covered with vegetation …
Published in International Journal of Environmental Planning and Development Architecture · Vol. 1, Issue 1, 2023 · pp. 44–57 Read article
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Antibiotics in the Modern Era: Challenges, Misuse, and the Fight Against Resistance
Abstract: Overuse and inappropriate use of antibiotics in human medicine, agriculture, and environmental pollution. It is one of the biggest public health risks of the 21st century. The discovery of new antibiotics slowdown and the emergence of multidrug-resistant (MDR) microorganisms has highlighted the urgent need to Creative approaches to fighting opposition. This review explores the current challenges in antibiotic use, the factors driving resistance, and the strategies being implemented to address …
Published in International Journal of Antibiotics · Vol. 2, Issue 1, 2025 · pp. 57–70 Read article
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English Literature in the Digital Era: Transformations and Trends
Abstract: English literature context has been changed significantly with modernisation of the digital age that is creating a massive impact on creation, dissemination, and interpretation of literature. When one considers the relationship between literature and digital innovation, one may summarize these disruptive forces as both a challenge to and opportunity for literature — a hybridization of past forms. It explores how digital technologies have transformed reading practices, textual analysis, and the …
Published in Emerging Trends in Languages · Vol. 2, Issue 2, 2025 · pp. 27–32 Read article
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Next-Generation mRNA Therapeutics: Self-Amplifying, Thermostable and Personalized mRNA Vaccines in the Era of Precision Medicine
Abstract: Messenger RNA (mRNA) technology has brought a major change in modern medicine, especially after its successful use in COVID-19 vaccines. However, early mRNA vaccines faced several problems such as low stability, strict cold storage requirements, and lack of personalized treatment. To overcome these challenges, next-generation mRNA technologies have been developed, including self-amplifying mRNA (saRNA), thermostable mRNA vaccines, and personalized mRNA vaccines. This article discusses the development of mRNA therapeutics, the …
Published in International Journal of Vaccines · Vol. 2, Issue 2, 2025 · pp. 38–54 Read article
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Ethical AI and Data Protection in the Era of Industry 5.0
Abstract: This paper provides a comprehensive analysis of the critical intersection between Responsible AI (RAI), data privacy, and the Industry 5.0 paradigm. Industry 5.0, defined by its human-centric, sustainable, and resilient pillars, introduces a fundamental paradox: its core requirement for human-AI collaboration necessitates the collection and processing of granular human data, creating direct conflicts with emerging global data privacy and AI regulations. This research utilizes a systematic integrative review methodology, analyzing …
Published in International Journal of Information Security Engineering · Vol. 4, Issue 2, 2026 Read article
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AI and ML-Driven Immersive Technologies: A New Era in Education
Abstract: The very fast adoption of Artificial Intelligence (AI) and Machine Learning (ML) in education has transformed contemporary teaching and learning ecosystems driven by advances in immersive technologies and the growing engagement of global technology leaders with virtual environments. AI-powered educational platforms enable adaptive and personalized learning pathways by dynamically adjusting content, pace and instructional strategies to learners’ preferences, abilities and learning styles by improving engagement, retention and academic outcomes. Deep …
Published in International Journal of Education Sciences · Vol. 3, Issue 1, 2026 · pp. 116–123 Read article
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Comparative Study of BERT Variants for Sentiment Analysis with Error Analysis
Abstract: The use of media is going up fast in India, and this has led to the rise of Hinglish. Hinglish is an informal blend of Hindi and English that people commonly use in everyday conversations, especially across social media platforms such as Twitter, Facebook, and WhatsApp. People use Hinglish to talk to each other in a way that is not very formal. Hinglish blends English vocabulary with informal usage, often …
Published in International Journal of Computer Science Languages · Vol. 4, Issue 1, 2026 · pp. 39–48 Read article