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14 articles for “D-Serine”
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Ab Initio and Density Functional Theory Studies on D-Serine
Abstract: The Hartee-Fock and density functional method (B3LYP) with 6–311++G (d, p) basis set were employed to study the structural and spectroscopic properties of amino acid D-serine in ground state. The structural and vibrational parameters of amino acid D-serine were obtained using optimised conformer. Using Vibrational Energy Distribution Analysis (VEDA) 4 program and theoretically obtained FTIR and FT-Raman data complete assignment of vibrations and analysis of fundamental modes of the compound …
Published in Research & Reviews : Journal of Physics · Vol. 9, Issue 3, 2020 · pp. 29–45 Read article
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Rheumatoid Arthritis and Stem Cell Therapies Perspectives for It
Abstract: Rheumatoid arthritis (RA) is a chronic autoimmune disorder characterized by systemic inflammation, primarily affecting synovial joints, leading to joint destruction and systemic complications. The pathogenesis involves immune system dysregulation, autoantibody production, and enzymatic imbalances. Enzymes, including matrix metalloproteinases (MMPs), serine proteases, and kinases, play crucial roles in these processes. Their dysregulation contributes significantly to disease progression through the imbalance of pro-inflammatory cytokines, oxidative stress, and extracellular matrix (ECM) degradation. MMPs, …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 15, Issue 2, 2025 Read article
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In Silico Screening and Evaluation of Some Metabolites from Momordica charantia in the Treatment of Peptic Ulcers
Abstract: Peptic ulcers are also called as or duodenal ulcers or gastric ulcers that are open sores generally develop in the lining of the stomach due to food and climatic factors. H. pylori infections are potentially the most dangerous and are linked to several diseases like diabetes, cancer, cardiovascular diseases, etc. In the present study, in silico screening and evaluation of some metabolites from Momordica charantia like Momorcharin, Momordicin, Metformin, Pioglitazone, …
Published in Research and Reviews : Journal of Computational Biology Read article
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IN SILICO SCREENING AND EVALUATION OF SOME METABOLITES FROM MOMORDICA CHARANTIA IN THE TREATMENT OF PEPTIC ULCERS
Abstract: Peptic ulcers are also called as or duodenal ulcers or gastric ulcers that are open sores generally develop in the lining of the stomach due to food and climatic factors. H. pylori infections are potentially the most dangerous and are linked to several diseases like diabetes, cancer, cardiovascular diseases, etc. In the present study, in silico screening and evaluation of some metabolites from Momordica charantia like Momorcharin, Momordicin, Metformin, Pioglitazone, …
Published in Research and Reviews : Journal of Computational Biology · Vol. 10, Issue 1, 2021 Read article
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The Efficacy of Fig Extract on Some Candida spp.
Abstract: The study was conducted in Al-Amin Laboratory by preparing the alcoholic extract of fig leaves, which were collected from the garden of a house in Najaf Governorate / Al-Shuara’a during the month of December 2023 for the purpose of testing its inhibitory effectiveness against two isolates of the fungus Candida albicans and Candida dubliniesis taken from Al-Amin Scientific Research Laboratory, where serial concentrations of the extract were prepared (12,9,6,3) mg/ml., …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 14, Issue 2, 2024 · pp. 19–23 Read article
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Biosynthesis of Amino Acids
Abstract: In this study, details of amino acids are given. Amino acids join to other amino acids and form protein. They are the ‘building blocks’ of the body. An overview of amino acid biosynthesis is given by glucose. Biosynthesis of serine from 3-phosphoglycerate and subsequent conversion of serine into glycine is explained with the diagram. General properties of amino acids are also given in this study. Keywords: Amino acids, building blocks, …
Published in Research & Reviews: A Journal of Bioinformatics · Vol. 4, Issue 1, 2017 · pp. 1–8 Read article
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Comparison of the Keratinase Gene Sequences of Fast, Slow and Intermediate Feather Degrading Strains of Bacillus licheniformis
Abstract: Feathers are composed of beta keratin which is an insoluble protein resistant to degradation. Bacillus licheniformis has a gene that codes for a keratinase enzyme that hydrolyzes feathers. The DNA sequences of the genes coding for keratinase enzymes of various strains of B. licheniformis were compared. Some strains of the bacteria hydrolyze feathers rapidly, some slowly, and some at an intermediate rate. The mature keratinase enzyme is composed of 274 …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 5, Issue 3, 2015 · pp. 1–9 Read article
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Regional Variation in Amino Acid Composition, Antioxidant and Antimicrobial Activity of Tasar Sericin from North and South Bihar
Abstract: This study investigates geographical differences in biochemical and functional characteristics of sericin obtained from Antheraea mylitta cocoons sourced from two regions of Bihar, India: Bhagalpur (North) and Banka (South). Sericin was isolated via an alkali-assisted autoclaving process. Amino acid profiles were determined using HPLC. Free radical scavenging capacity was measured through DPPH, ABTS, and hydrogen peroxide assays. Antibacterial and antifungal effects were tested against Staphylococcus aureus, Escherichia coli, and Candida …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 16, Issue 2, 2026 Read article
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Regional Variation in Amino Acid Composition, Antioxidant and Antimicrobial Activity of Tasar Sericin from North and South Bihar
Abstract: This study investigates geographical differences in biochemical and functional characteristics of sericin obtained from Antheraea mylitta cocoons sourced from two regions of Bihar, India: Bhagalpur (North) and Banka (South). Sericin was isolated via an alkali-assisted autoclaving process. Amino acid profiles were determined using HPLC. Free radical scavenging capacity was measured through DPPH, ABTS, and hydrogen peroxide assays. Antibacterial and antifungal effects were tested against Staphylococcus aureus, Escherichia coli, and Candida …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 16, Issue 2, 2026 · pp. 1–10 Read article
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3D-QSAR Studies on Protein Phosphatase 2A Inhibitors as Anti-cancer Agents
Abstract: The tremendous efforts by researcher indicates that cantharidin, nor cantharidin and their analogues shows anti-cancer activity due to their inhibition of cancer cell lines such as HT29, SW480, MCF-7, A2780, H460, A431, DU145 and L1210. The anti-cancer activities of cantharidin, nor cantharidin and their analogues involve the inhibition of serine/threonine protein phosphatises (PPs) activity. In this study, three-dimensional quantitative structure activity relationship (3D-QSAR) like comparative molecular field analysis (CoMFA), and …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 5, Issue 3, 2018 · pp. 1–19 Read article
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UV Induced Increase in Activity of Subtilisin from Bacillus subtilis MTCC441
Abstract: Microorganisms are constantly exposed to varying physical, chemical and biological conditions which induce morphological, biochemical and genetic changes in them. These changes may be deleterious to some organisms whereas others develop mechanisms to overcome such stresses. This study was conducted to understand the microbiological and biochemical changes in bacteria under conditions of UV stress. Bacillus subtilis MTCC441, a ubiquitous, spore forming bacterium was chosen as the model organism for this …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 4, Issue 1, 2014 · pp. 22–27 Read article
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Aurora Kinase: A Target for Cancer Therapy
Abstract: Aurora kinases are the enzymes that belong to the family of serine/threonine kinases. It consists of Aurora-A (AURK-A), Aurora-B (AURK-B) and Aurora-C (AURK-C), which are the essential kinases for cell division through mitosis regulation especially for the process of chromosomal segregation. Aurora kinases are involved in meiosis regulation along with the regulation of mitosis. Inhibition of Aurora kinase leads to neglected cell division. Various cancer studies generally deal with gene …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 9, Issue 3, 2019 · pp. 10–17 Read article
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The Role of Quercetin, Curcumin, Eugenol, and Andrographolide in COVID-19 Treatment: A Review of Their Mechanisms of Action and Clinical Efficacy
Abstract: The world has recently experienced the covid diseases. It became the global worry with no remedy initially. Later, different antiviral medications in the form of injections and nasal sprays began to be employed. Many studies have been conducted to determine the antiviral effects of phytochemical substances. The corona virus's spike protein interacts with the ACE2 receptors on the alveoli's surface to enter the cell. After that, the polyprotein is transformed …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 13, Issue 1, 2023 · pp. 27–38 Read article
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Perspectives on ‘Kamsaharitaki’: an Ayurvedic Formulation for COVID-19 related Multisystem Inflammatory Syndrome (MIS)
Abstract: Background and Aim: Angiotensin-converting enzyme 2 receptor (ACE2), together with Transmembrane protease serine 2 (TMPRSS2), is a protein receptor for SARS-CoV-2 virus in the host subject; expression of ACE2 and TMPRSS2 reveals the multidimensional character of COVID-19 infection. SARS-CoV-2 Prominently induces pulmonary and systemic injury with other synergistic mechanisms. Preexisting chronic inflammatory conditions markedly sustain and aggravate the severity and cytokine storm. Inflammatory responses are closely linked with COVID-19 severity …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 11, Issue 1, 2022 Read article