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8 articles for “Colon drug delivery system”
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Drugs and Polymers Used for Colon Specific Drug Delivery System with Current Trends: A Systematic Review
Abstract: Due to greater flexibility in design of dosage form and high patient compatibility, oral route of administration is the most preferred route but the gastrointestinal tract has many types of other undefeatable barriers to drug delivery. In oral colon-specific drug delivery system, colon has a large amount of lymphoma tissue which facilitates direct absorption into the blood, negligible brush border membrane activity, and much less pancreatic enzymatic activity as compared …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 4, Issue 3, 2013 · pp. 1–8 Read article
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Flaxseed-Based Drug Delivery Systems: Advancing Colon Cancer Treatment
Abstract: Flaxseed (Linum usitatissimum) has long been appreciated for its rich nutritional profile, including essential fatty acids (such as α-linolenic acid), plant fibers, and lignans. Recent research has focused on its potential as a novel drug delivery system (DDS) for the treatment of colon cancer. This review explores the bioactive constituents of flaxseed, their pharmacological activities, and innovative approaches to the use of flaxseed extracts in drug delivery for the treatment …
Published in Emerging Trends in Personalized Medicines · Vol. 2, Issue 1, 2025 · pp. 54–59 Read article
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Design And Evaluation Of Meloxicam Tablet For Colon Cancer
Abstract: Meloxicam, recognized as a preferential COX-2 inhibitor, has emerged as a promising chemopreventive agent for colorectal cancer. Leveraging its local and targeted action on the colon, Meloxicam proves to be a formidable component in the prevention of colorectal malignancies. This study aims to innovate by formulating and evaluating a targeted tablet delivery system for Meloxicam, emphasizing site-specific and instant drug release in the colon, thereby maximizing its therapeutic efficacy in …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 10, Issue 3, 2023 · pp. 1–7 Read article
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A Review of basic Concept of Specific Drug Delivery System
Abstract: ABSTRACTThis review focus going on targeted drug delivery via Nanoparticles as a Special composition that couple a receptor site to a Nanosized , drug-loaded transporter as a budding means to get improved effectiveness of a drug at the site of significance. The conception of targeted drugs is not new, but since to 1906 while Ehrlich initial postulate the ‘magic bullet’. therefore is must to build up a appropriate drug system …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 13, Issue 3, 2022 · pp. 21–26 Read article
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Comprehensive Overview of Carbohydrate Polymers
Abstract: Targeting drug delivery specifically to the colon has become increasingly crucial for treating various colonic diseases like colorectal cancer, amebiasis, ulcerative colitis, and Crohn’s disease. Numerous strategies have been developed for this purpose, including using enzymatically degradable polymers, employing prodrug-based approaches, coating drugs with polymers sensitive to time or pH changes, utilizing osmotically and pressure-controlled delivery systems. Polysaccharides activated by the colon's physiological environment show significant potential as they offer …
Published in International Journal of Membranes · Vol. 1, Issue 1, 2024 · pp. 8–21 Read article
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Development and Characterization of 5-Fluorouracil Cubosomal Nanosponge Tablet for Colon Targeting
Abstract: The objective of this study was to develop nano-scale delivery system to improve nanometric size range, percentage drug entrapment efficiency, controlled release of the incorporated drug and the protection against degradation. 5-FU loaded cubosomal dispersion was prepared by the bottom up technique and formulation was characterized. From this, 5-FU cubosomal nanosponges were prepared by the emulsion solvent diffusion method using various pH dependent polymers and evaluated, encapsulation of this formulation …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 10, Issue 2, 2019 · pp. 9–18 Read article
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Review on Formulation and Evaluation of Herbal Gel of Moringa oleifera and Aloe vera for management of acne
Abstract: Acne vulgaris is a prevalent chronic inflammatory disorder of the pilosebaceous units, characterized by excessive sebum production, follicular hyperkeratinization, bacterial colonization, and inflammation. Conventional therapies often result in side effects and the development of drug resistance, prompting the exploration of natural alternatives. This review highlights the potential of Moringa oleifera and Aloe vera in acne management via topical drug delivery systems (TDDS). Moringa oleifera is rich in bioactive compounds such …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 13, Issue 1, 2026 · pp. 10–16 Read article
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Nanotechnology in Surgical Drains: Reducing Infections and Promoting Healing Post-Surgery
Abstract: Surgical drains are widely used in postoperative care to evacuate accumulated fluids, minimize dead space, and reduce complications such as hematoma and seroma formation. Despite their clinical importance, conventional drains are frequently associated with retrograde bacterial migration, biofilm formation, and increased risk of surgical site infections (SSIs), which contribute significantly to postoperative morbidity and prolonged hospital stay. Recent advancements in nanotechnology have enabled the development of nano-functionalized surgical drains with …
Published in Research and Reviews : Journal of Surgery · Vol. 15, Issue 2, 2026 · pp. 54–67 Read article