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13 articles for “Cephalosporin”
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Prevalence and Antibiogram Profile of Uropathogens Isolated from Symptomatic and Asymptomatic Female Patients with Urinary Tract Infections and its Associated Risk Factors: Focus on Cephalosporin
Abstract: Urinary tract infections (UTIs) are common among women. Here, the present study probes the prevalence of urinary tract infection (UTI), assess the adequacy of empirical therapy, susceptibility of antibiotics and resistance pattern of bacteria responsible for UTI and its associated risk factors. A total of 1309 urine samples were collected from UTI suspected female patients of tertiary care hospitals between the ages of 18-49. Moreover, a total of 207 urine …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 7, Issue 1, 2018 · pp. 32–41 Read article
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A Case Report on Ceftriaxone Induced Immediate Allergic Reaction
Abstract: The most common classes of drugs causing hypersensitivity reaction are antibiotics especially β-lactam antibiotic: cephalosporin’s and penicillin’s. Ceftriaxone, a third generation cephalosporin is used for variety of infections. This drug is associated with rare as well as mild side-effects such as urticaria, skin rash, diarrhea, vomiting, transient neutropenia, and hemolytic anaemia etc. We hereby try to present an adversary case report of a 19 years old male patient in which …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 10, Issue 2, 2020 · pp. 33–35 Read article
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Phenotypic detection of ESBL production in Escherichia coli isolated from UTI patients of Kalaburagi city, Karnataka, India
Abstract: Aim: The principle aim of present conducted study was phenotypic detection of extended spectrum ß-lactamase (ESBL) production in Escherichia coli strains isolated from urinary tract infected patients of Kalaburagi city, Karnataka, India.Materials and Methods: The positive E. coli isolates selected for the following study was isolated from urine sample of UTI patients. The screening of positive E. coli was done and antibiotic susceptibility test and MIC were determined as per …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 7, Issue 2, 2017 · pp. 1–6 Read article
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Extended-spectrum beta-lactamases (ESBLs) and Metallo-beta-lactamases (MBLs): A Review
Abstract: Gram-negative bacteria produce extended-spectrum beta-lactamases (ESBLs) and metallo-beta-lactamases (MBLs), enzymes that play a crucial role in antibiotic resistance. These enzymes enable the bacteria to withstand a wide array of beta-lactam antibiotics, including penicillins, cephalosporins, and carbapenems. The production of these enzymes, particularly by organisms, such as Escherichia coli and Klebsiella pneumoniae, complicates treatment options for severe infections, leading to increased morbidity and mortality in clinical settings. ESBLs are primarily responsible …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 15, Issue 2, 2025 · pp. 8–19 Read article
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Herbal Frontiers: The Role of Alternative Remedies in Combating Typhoid Fevers
Abstract: Typhoid fever, caused by Salmonella typhi, remains a major health challenge, particularly in developing regions where sanitation and healthcare resources are limited. With an estimated global incidence of 17 million cases annually, the disease poses a significant public health burden. The growing resistance to conventional antibiotics, such as fluoroquinolones and third-generation cephalosporins, exacerbates treatment challenges. This has spurred interest in alternative remedies, including herbal and homeopathic treatments.Herbal medicine offers a …
Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 1, 2025 Read article
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Oral Eruption Associated With Cefuroxime Axetil: An Unusual Complication
Abstract: Cefuroxime Axetil is an oral cephalosporin class of antibiotic having broader gram negative activity and used in infective conditions caused by facultative bacteria and anaerobes such as respiratory tract infection, intra-abdominal infection, pelvic inflammatory disease and diabetic foot infection etc. Severe oral eruption associated with swelling on lips and mucosal erythemas are not described previously as ADR due to Cefuroxime. Here, we report a case of severe oral eruption induced …
Published in Research and Reviews: A Journal of Health Professions · Vol. 5, Issue 3, 2015 · pp. 16–18 Read article
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Neonatal Sepsis: A Study on Isolated Pathogens and Their Susceptibility Pattern at Tertiary Care Hospital in Rural Setting
Abstract: Neonatal sepsis is one of the most important causes of infant mortality and morbidity. In spite of availability of broad spectrum antibiotics, treating sepsis has become a challenge due to emergence of resistant strains from time to time. The present study is aimed at to isolate the organisms causing sepsis in neonates and their antibiotic susceptibility patterns. From April 2013 to June 2014, 167 blood samples were collected from clinically …
Published in Research and Reviews: A Journal of Medicine · Vol. 5, Issue 2, 2015 · pp. 11–15 Read article
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Nanostructured TiO2 Prepared Through Sol–Gel Method Enhances the Activity of Antibiotics against Gram Positive Bacteria
Abstract: The synthesis and bioactivity of titanium dioxide (TiO2) nanoparticles has been extensively studied. However, the antibacterial activity of TiO2 individually or in combination with different antibiotics has not been demonstrated. TiO2 was prepared by sol–gel process using precursor Titanium (IV) Chloride (TiCl4) and concentrated sulfuric acid in 4 h of calcinations at 550 °C and the enhancement effect of TiO2 nanoparticle on the antibacterial activity of different antibiotics was evaluated …
Published in Journal of Nanoscience, NanoEngineering & Applications · Vol. 2, Issue 1, 2012 · pp. 6–12 Read article
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A Method of Universal Primer Design for The Detection of Diverged CTX-M Beta-Lactamases in Multi-Drug Resistant Superbugs
Abstract: Complexity of many diverged β-lactamases in common multi-drug resistant bacteria has reached very high level. We found >40% of common bacteria in Kolkata water bodies were ampicillin resistant and reported clinical isolates were >95% ampicillin resistant worldwide. More than twenty unique sequence classes of β-lactamases were known to cause MDR inactivating penicillin, cephalosporin and carbapenem drugs. Further, there are other diverged MDR genes like drug efflux genes (acrAB, mexAB-EF, tetA), …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 9, Issue 2, 2019 · pp. 1–10 Read article
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Isolation, Characterization and Molecular Identification of Potential Probiotic Bacterium, Bacillus amyloliquefaciens CS4 from gut of Snakehead Fish, Channa striata (Bloch, 1793)
Abstract: The present study was to isolate and characterize the potential probiotic bacterium from the gutof healthy fish, Channa striata. Totally, 37 bacteria were isolated from the gut region, in whichonly 25 isolates that showed catalase negative were selected. Among the selected isolates, CS4exhibited maximum inhibitory activity against fish (Aeromonas hydrophila, Vibrio harveyi,Vibrio parahaemolyticus) and human (Serratia marcescens) pathogenic bacteria. Theisolate CS4 exhibited potential tolerance to 0.5% bile salts at 24 …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 9, Issue 2, 2019 · pp. 1–10 Read article
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Design and Evaluation Cefaclor Microspheres for Bioavailability Enhancement
Abstract: This study attempted to formulate microspheres for oral administration of Cefaclor by using different polymers like Hydroxypropyl methylcellulose (HPMC) K4M, (HPMC) K15M and Ethylcellulose (EC) which increases the gastric residence time and thereby the bioavailability. Solvent evaporation method was found to be the best due to its ease of fabrication without compromising the activity of the drug. Cefaclor is a second-generation cephalosporin antibiotic used to treat certain ear, lung, skin, …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 6, Issue 3, 2019 · pp. 39–48 Read article
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A Study and Report on Role And Impact Of Clinical Pharmacist in assessment of Prescribing Cascades In Antibiotics Usage For Infectious Diseases in Promotion of Rational Drug Usage
Abstract: ABSTRACT:A Prescription cascade occur when the healthcare providers fail to recognise that the new symptoms are actually the side effects of the medications under treatment. The study was based on the role and impact of clinical pharmacist in assessment of prescribing cascades in antibiotics usage for infectious diseases in department of general medicines and paediatric department at ESI hospital, Indiranagar, Bangalore, Karnataka, India. The main motto of the study was …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 9, Issue 3, 2022 · pp. 1–14 Read article
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Assessment Of Prescription Pattern Of Antibiotics In Geriatric Population At Tertiary Hospital
Abstract: Antibiotics is an anti-infective agent that are capable of Destroying and inhibiting the growth of micro-organisms and it is derived from Bacteria or Moulds that are toxic to other bacteria. Alexander Fleming in1928,accidently discovered Penicillin notatum . he found that penicillin notatum are extremely effective even at very low concentration. In elder population Aging process causes changes in nervous system, cognition , vision , hearing , memory, learning , intelligence …
Published in Trends in Drug Delivery · Vol. 10, Issue 2, 2023 · pp. 11–15 Read article