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26 articles for “Antidepressant activity.”
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The Pharmacological Importance of Quercus incana: A Review
Abstract: Baloot or Quercus incana, commonly known as blue jack oak or cinnamon oak, a large evergreen tree, belongs to genus Quercus, largest genus of family Fagaceae, approximately 900 species distributed in tropical and subtropical regions of Asia as well as temperate zones of Northern Hemisphere The genus Quercus have long been considered among the clades of woody angiosperms in terms of species diversity, horticulture merit and ecological dominance, industrial and …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 11, Issue 1, 2021 · pp. 15–19 Read article
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Anti-Depressant Activity of Aqueous Leaf Extract of Pergularia daemia in In-Vivo Animal Models
Abstract: The plant leaf of Pergulariadaemia was used for management of depressive state in various traditional system of medicine like Ayurveda, Unani and Siddha. In the absence of substantial pharmacological data, the present study attempts to study the antidepressant activity of Pergulariademia aqueous extract, by using forced swim test and tail suspension test. Animals were grouped into four treatment groups (n=4) and injected with normal saline (control), imipramine-10 mg/kg (Standard drug), …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 5, Issue 3, 2015 · pp. 21–26 Read article
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Boswellia serrata: A Review on its Phytochemical and Therapeutic Potential
Abstract: Kundur or Boswellia serrata belongs to the genus Boswellia of Burseraceae family. It is usually found in Oman and Yaman, its effectiveness persists for 20 years. Its bark and gum are used for medicinal properties but Boswellia are well-known for producing a gum resin that is known as olibanum or frankincense. Gum-resin comprises triterpenes of oleanane, ursane and euphane series. The major chemical constituents reported for anti-inflammatory, antiproliferative and anticancer …
Published in Research & Reviews : Journal of Botany · Vol. 10, Issue 1, 2021 · pp. 16–22 Read article
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Evaluation of Anthelmintic, Analgesic and Neuropharmacological activity of Heliotropium indicum
Abstract: The present study was performed to evaluate the anthelmintic, analgesic and neuropharmacological activity of the methanol extract from the leaves of Heliotropium indicum. Anthelmintic activity was investigated using earthworm (Pheretima posthuma) & fresh leaf juice of the plant. In anthelmintic activity test, the time of paralysis for fresh juice was range from 7 min 55 s to 26 min 55 s whereas the time ranges for standard drug albendazole was …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 9, Issue 1, 2019 · pp. 31–38 Read article
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Role of Neuropeptides in the Treatment of Major Depression Disorder: The Recent Updates
Abstract: Revelation of the part of neuropeptides as signaling atoms within the nervous system raised trust within the pharmaceutical field approximately 25. long time back Many neuropeptides, especially CRH, AVP, and substance P . whose receptors are presently focused on by little atoms to diminish side effects of discouragement and uneasiness, shows up to be related to the improvement and movement of temperament disarranges trouble. Neurotrophins, not exactly neuropeptides, may also …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 14, Issue 3, 2024 · pp. 1–12 Read article
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Systematic Analysis of the Pharmacological Properties of Different Plant Parts of Madhuca sp.
Abstract: Madhuca sp., a perennial tree belonging to the Sapotaceae family, is widely distributed across South and Southeast Asia. It holds considerable value across the food, beverage, and pharmaceutical sectors. The growing interest among cultivators, agronomists, and industry stakeholders stems from the diverse bioactive potential documented across different parts of the plant, including the bark, leaves, seeds, and flowers. Traditional and emerging evidence points to a wide spectrum of pharmacological actions, …
Published in Research & Reviews : Journal of Botany · Vol. 15, Issue 2, 2026 · pp. 1–11 Read article
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REVIEW OF CYTISUS SCOPARIUS
Abstract: Cytisus scoparius is a shrub which is commonly known as scotch broom belonging to the family Fabaceae. The plant has different uses in medicine were it is used for the oedema and gout treatment. The plant contains different chemical constituents such as alkaloids, flavonoids, isoflavone and the main constituents found in plant is mainly scoparin. There have been various researches done on pharmacological activity of the plant such as antioxidant, …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 10, Issue 2, 2023 · pp. 32–35 Read article
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Review on Cyperus scariosus: A Potential Medicinal Plant
Abstract: Saad kofi or Cyperus scariosus, known as Nagarmotha in India, is a delicate grass which is an angiosperm belonging to family Cyperaceae. Indian species of this plant is called motha. The best quality of saad is heavy in weight, rough from outside with strong aroma, whitish inside, highly bitter in taste. Its root extracts and volatile oil are used for medicinal purposes. Nagarmotha is also prescribed by local herbal medicine …
Published in Research and Reviews : Journal of Crop science and Technology · pp. 28–32 Read article
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Smilax zeylanica linn: Pharmacognostic, Taxonomical and Phytochemical Status
Abstract: Plants have always been a center of attraction since ancient times and widely exploited for various needs by humans. Smilax zeylanica linn is a small woody climber belonging to the family Smilacaceae. Smilax china, a very well-known plant used for production of Sarsaparilla is also a member of this family. Thus S. zeylanica is used as a substitute for S. china for obtaining sarsaparilla or chopachini. From the leaves up …
Published in Research & Reviews : Journal of Herbal Science · Vol. 11, Issue 1, 2022 · pp. 1–14 Read article
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Computational Investigation of Phytochemicals Targeting AKT1 for Major Depressive Disorder: A Molecular Docking and ADMET Study
Abstract: Major depressive disorder (MDD) is a prevalent neuropsychiatric condition affecting approximately 280 million individuals worldwide, with women exhibiting a 50% higher likelihood of diagnosis than men. Despite significant advancements in treatment, MDD remains a chronic and relapsing disorder, necessitating the exploration of novel therapeutic interventions. This study focuses on the AKT1 gene, a key player in neuropsychiatric disorders, and investigates its interactions with natural phytochemicals as potential alternatives to conventional …
Published in Research and Reviews : Journal of Computational Biology · Vol. 14, Issue 2, 2025 Read article
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Exploring the Role of MAPK3 in Major Depressive Disorder: Molecular Docking, Dynamics, and Binding Free Energy Analysis of Natural Compounds as Alternatives to Conventional Drugs
Abstract: Major Depressive Disorder (MDD) is a prevalent neuropsychiatric disorder with limited treatment efficacy and significant side effects associated with conventional antidepressants. Recent studies have highlighted the role of mitogen-activated protein kinase 3 (MAPK3) in the mechanisms underlying MDD, positioning it as a potential target for the development of novel therapeutic drugs. In this study, we employed various computational approaches to explore natural compounds as viable alternatives to synthetic antidepressants. Researchers …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 3, Issue 2, 2025 · pp. 53–68 Read article
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Review on Elaeocarpus Ganitrus (Rudraksha)
Abstract: The seed of Elaeocarpus Ganitrus, also known as Rudraksha, is renowned for its electromagnetic characteristics. Recent scientific research has demonstrated that this seed possesses natural electromagnetic properties which can effectively treat various chronic diseases. This study focuses on the phytochemical screening and thin layer chromatographic analysis of the extract obtained from Elaeocarpus Ganitrus seeds, which belong to the Elaeocarpaceae family. Bombay, and is commonly grown as an ornamental tree in …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 11, Issue 2, 2024 · pp. 8–15 Read article
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Ethnobotanical, Phytochemical, and Pharmacological Aspects of Piper nigrum (Filfil siyah): An Update
Abstract: Piper nigrum (Filfil siyah) is a very popular medicinal plant. It is used in Unani as well as the Ayurvedic System of medicine for several diseases due to their diverse pharmacological potentials and minor side effects. In the Unani System of Medicine, it is recommended for the treatment of Nafkh al-Mi‘da (Flatulence in the stomach), Qulanj Rihi (colic due to flatulence), Waj-ul-Meda (Gastric Pain), Kasir-e-Riyah (Carminative), Zofe-Ishtiha (Anorexia), Muharrik (Stimulant), …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 11, Issue 3, 2022 · pp. 26–35 Read article
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COMPREHENSIVE APPROACHES TO UNDERSTANDING AND MANAGING ALZHEIMER’S DISEASE
Abstract: Alzheimer’s disease is an advanced neurodegenerative disorder described by intense memory loss. It strictly affects the patient’s quality life. The popularity of AD has been increasing in recent years. It is the most common form of mental disorder affecting more than 20 million people in the world. The Alzheimer’s disease is treated with cholinesterase inhibitors or NMDA-receptor (N-methyl D-aspartate) antagonists but here the question is about the therapeutic effect of …
Published in International Journal of Tropical Medicines · Vol. 2, Issue 1, 2025 · pp. 1–9 Read article
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Effect of Dimethyl Sulfoxide Extract on Different Parts of a Medicinal Plant:Euphorbia hirta L. Against Escherichia coli and Staphylococcus aureus
Abstract: Euphorbia hirta has been widely used by tribal as traditional medicine in the treatment against infectious pathogens. Euphorbia hirta Linn. is a perennial herb belonging to the family Euphorbiaceae. It is a potent medicinal plant and has established its sedative and anxiolytic activity. It has analgesic, antipyretic, anti-inflammatory, antidepressant for blood pressure, antihypertensive and antioxidant properties. Effect of dimethyl sulfoxide extract on different parts (leaf, bud and stem) of Euphorbia …
Published in Research and Reviews : A Journal of Biotechnology · Vol. 5, Issue 2, 2015 · pp. 30–33 Read article
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The Beneficial Effects of Short-term Therapy of Antidepressants on the Electrocardiograph Records in Patients Presented with Depression
Abstract: Normal 0 false false false EN-US X-NONE AR-SA Abstract:Drugs that are used in the psychiatric clinics or inpatients may interfere with the electrical activity of the heart and in certain circumstances may induce fatal cardiac arrhythmias. This study aimed to demonstrate the effects of short-term antidepressants compounds on the ECG records using the prolongation of QTc and JTc intervals as an indication of the harmful effects of antidepressants. A total …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 5, Issue 1, 2015 · pp. 19–23 Read article
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Therapeutic Importance of Sumbul-ut-Teeb (Nardostachys jatamansi DC)
Abstract: Background: Sumbul-ut-teeb is an important medicinal plant and has been extensively used in the Indian system of medicine. Sumbul-ut-teeb is an erect, small, perennial, rhizomatous herb. There is a plethora of experimental and clinical evidence showing its medicinal activity. Varieties: There are three varieties of Sumbul-ut-teeb that are mentioned in the Unani System of Medicine as a drug that is, Sumbul Hindi, Sumbul Romi, and Sumbul Jabli (pahadi). Sumbul Hindi …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 10, Issue 1, 2023 · pp. 10–17 Read article
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Global Burden of Major Depressive Disorder: Prevalence, Diagnosis, and Impact: A Comprehensive review
Abstract: In this review, we will discuss about the major depressive disorders on the basis of neurobiological changes. MDD, a prevalent psychiatric condition, manifests as a complex interplay of genetic, environmental, and physiological factors with a substantial impact on individuals and societies globally. Here the clinical assessment is fully based on diagnosis and the statistical manual for mental disorder, 5th edition (DSM-5). The pathophysiology involves Diagnosis alterations in neurotransmitter systems, dysregulation …
Published in Emerging Trends in Metabolites · Vol. 1, Issue 1, 2024 · pp. 54–62 Read article
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Pharmacognostical and Pharmacological Review of Urtica dioica L.
Abstract: Urtica dioica (stinging nettle) belonging to family Urticaceae, is obtained from word ‘uro’ to burn or ‘urere’ denotation to sting. It is found in the Himalayas region from Kashmir to Kumaon region (Uttarakhand.). The plant has been used in traditional system of medicines especially uses nasal and menstrual haemorrhage, eczema, rheumatism, nephritis, anaemia, diarrhoea, jaundice and epilepsy. The plant contains bioactive constituents like tannins, fatty acids, flavonoids, sterols, isolectins, proteins, …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 6, Issue 2, 2019 · pp. 23–29 Read article
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An Insight to Diagnosis and Management of Druginduced Hepatotoxicity: An Overview
Abstract: (ADRs) Adverse Drug Reactions are constitute and mutual chief health problem. Throughout the last period liver toxicity has remained one of the most recurrent reasons for pharmacovigilance protection intelligences and the withdrawal from the marketplace of an accepted medicinal product. Liver is a main organ elaborate in the systemic deposition and decontamination of exogenous and endogenous ingredients. Liver disfunction challenges not only health care specialists but also the pharmaceutical manufacturing …
Published in Trends in Drug Delivery · Vol. 8, Issue 2, 2023 · pp. 39–54 Read article