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21 articles for “Anticoagulant”
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Rivaroxaban: A Comprehensive Review of an Anticoagulant Revolution
Abstract: Rivaroxaban, a prominent direct oral anticoagulant (DOAC), has garnered attention for its pivotal role in preventing and treating thromboembolic diseases. Its introduction into clinical practice has marked a significant advancement in anticoagulant therapy. The mechanism of action of rivaroxaban involves selective inhibition of factor Xa, a crucial component in the coagulation cascade. This targeted approach distinguishes it from traditional anticoagulant and contributes to its efficacy. The significance of rivaroxaban lies …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 10, Issue 3, 2023 · pp. 17–23 Read article
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Navigating the Principles and Practice of Oral Anticoagulant Therapy: A Comprehensive Healthcare Guide
Abstract: Oral anticoagulant therapy plays a critical role in the prevention and treatment of thromboembolic disorders, including atrial fibrillation (AF), venous thromboembolism (VTE), and mechanical heart valve replacement. This research article aims to provide a comprehensive overview of the principles and practice of oral anticoagulant therapy, focusing on the mechanisms of action, pharmacokinetics, clinical indications, monitoring, and management of associated complications. The cornerstone of oral anticoagulant therapy includes vitamin K antagonists …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 15, Issue 1, 2025 · pp. 76–82 Read article
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An Overview of Anticoagulants in Treatment of Thrombosis and Related Disorders: A review
Abstract: With the increasing ageing of population, clinicians are encountering patients with atrial fibrillation and venous thromboembolism who require anticoagulant therapy to prevent stroke and systemic embolism. Due to its high prevalence and unfavorable results, the treatment of thromboembolic disease has become a clinically important area. Traditional anticoagulants such as heparin, low molecular weight heparin, and warfarin have been used to prevent and treat venous and arterial thrombosis. However, bleeding problems, …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 13, Issue 2, 2023 · pp. 1–8 Read article
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A Review of the Use of Direct Oral Anticoagulants for Treating Venous Thromboembolism in Patients with Cancer
Abstract: Venous thromboembolism is a common complication in patients with cancer. Treatment guidelines have long recommended low molecular weight heparin as the first-line therapy. There is a growing body of literature regarding direct oral anticoagulants in treating venous thromboembolism in these patients. The data regarding the use of direct oral anticoagulants in this population is reviewed as are the most current guidelines from the National Comprehensive Cancer Network. Keywords: Anticoagulants, venous …
Published in Research and Reviews: Journal of Oncology and Hematology · Vol. 7, Issue 2, 2018 · pp. 15–17 Read article
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Assessment of Knowledge Regarding Venous Thromboembolism Prophylaxis Among Staff Nurses at Intensive Care Units in a Selected Hospital in Palakkad
Abstract: The present study was conducted to assess the knowledge regarding venous thromboembolism prophylaxis among staff nurses in intensive care units in a selected hospital in Palakkad. The objectives of the study were to assess the knowledge regarding venous thromboembolism prophylaxis among staff nurses in intensive care units, and to associate nurses’ knowledge regarding venous thromboembolism prophylaxis with sociodemographic variables. A quantitative, nonexperimental descriptive exploratory research design was selected. Thirty samples …
Published in International Journal of Emergency and Trauma Nursing and Practices · Vol. 2, Issue 1, 2024 · pp. 14–21 Read article
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Tranexamic Acid Mouth Rinser as a Drug of Choice among Haemostatic Agent after Tooth Extraction in Patients who are on Anti-Coagulant and Anti Platelet Medical Therapy
Abstract: Oral surgery procedure became difficult to manage in patients, who are on anti-platelet and anti-coagulant medication. Risk of thromboembolism should be balance by surgeon via reducing or stopping anti platelet and anticoagulant therapy in such patients, because there are more risk of excessive post extraction bleeding if anticoagulation or anti platelet medications are prescribed at therapeutic dose during surgical procedure. Fibrin formation mechanism become impaired in such patients, as a …
Published in Research and Reviews: A Journal of Dentistry · Vol. 12, Issue 2, 2021 · pp. 33–44 Read article
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Literature Review of Irsal-e-Alaq (Leech Therapy) in Unani and Modern Science
Abstract: The Unani system of medicine is based on the humoral theory (Nazriya Akhlat) postulated by Buqrat. According to this theory, all illness is caused by an imbalance of one of the four body humors that is, blood, phlegm, yellow bile and black bile. Irsal-e-alaq is one of the oldest and widely practiced means of Ilaj-bit-tadbeer for local evacuation of morbid humours. It is a procedure of treatment with the use …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 6, Issue 3, 2019 · pp. 21–29 Read article
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Clinical experience with Ayurvedic Treatment in Case of Rheumatoid Arthritis – Ayurvedic review and Case study
Abstract: Rheumatoid arthritis is the most found inflammatory auto immune disease with unknown etiology. Many clinical features and treatment strategies of RA are associated with multiple joint diseases. The clinical phenotype of Rhematoid arthritis is a symmetrical, deformed polyarthritis of small and large joints, which is often associated with features of the disease. The treatment typically involves ongoing management with periods of worsening symptoms followed by periods of improvement. Features of …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 11, Issue 2, 2024 · pp. 1–8 Read article
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A Comprehensive Review on Pharmacological Properties of Coumarins
Abstract: Coumarins are a diverse group of secondary metabolites found in a variety of plant species (over 1200 different coumarins have been identified from natural sources, especially plants), as well as in fungi and microorganisms. Coumarin is a simple, widely occurring chemical structure in nature, present in many plants, fungi, and bacteria. In recent years, these natural compounds have attracted growing interest from the scientific community due to their broad spectrum …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 2, Issue 2, 2024 · pp. 12–17 Read article
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From Concept to Clinical Practice: A Detailed Review of Total Artificial Heart Devices
Abstract: Total artificial heart (TAH) devices are mechanical systems designed to take over the role of a failing heart in patients with severe heart failure. Unlike ventricular assistance devices (VADs), which only support one side of the heart, TAHs replace both ventricles, providing a possible solution for patients who cannot receive a heart transplant. Over time, TAH technology has evolved with a focus on improving biocompatibility, reducing complications related to the …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 15, Issue 1, 2025 · pp. 1–4 Read article
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Blood Cell Saver Machine
Abstract: Intraoperative Cell Salvage (ICS) is a crucial technique in modern surgical practice aimed at minimizing the need for allogeneic blood transfusions. By collecting, filtering, washing, and re-infusing a patient’s own blood lost during surgery, ICS provides a safer and cost-effective alternative to donor transfusion, reducing the risk of transfusion-related infections and immunologic reactions. Initially conceptualized in the early 19th century, ICS technology evolved significantly with the introduction of the Cell …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 15, Issue 2, 2025 · pp. 51–59 Read article
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Lipid Oxidation, Maillard Reaction, and Their Possible Interrelation in Selected Foods and Model Systems – A Review
Abstract: The present article highlights on the medicinal value of leeches. Leech belongs to phylum Annelida have played a significant role in ancient medicine for centuries, with their therapeutic and medicinal applications dating back to ancient human civilizations such as those of Egypt, Greece, and India. Historically, incidences shows it associated with blood letting, leeches were believed to restore balance to the body’s humors. In recent times, new experiments are being …
Published in Research & Reviews : Journal of Food Science & Technology · Vol. 15, Issue 1, 2026 · pp. 7–15 Read article
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“REVIEW ARTICLE ON TRIDAX PROCURMBENS HERBAL ANTIBACTERIAL CREAM”
Abstract: Abstract Tridax procumbens (L.), also referred to as coat buttons or tridax daisy, is a common plant in the Asteraceae family that is well-known for its exceptional pharmacological and therapeutic properties. This plant has long been utilized as an anticoagulant, antifungal, insect repellent, wound healer, and hepatoprotective agent in Indian Ayurveda. With a focus on its medicinal and formulation features, the current study offers a thorough summary of its botanical …
Published in Recent Trends in Cosmetics · Vol. 3, Issue 1, 2026 · pp. 21–29 Read article
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An overview on the Medicinal Value of Leeches
Abstract: The present article highlights on the medicinal value of leeches. Leech belongs to phylum Annelida have played a significant role in ancient medicine for centuries, with their therapeutic and medicinal applications dating back to ancient human civilizations such as those of Egypt, Greece, and India. Historically, incidences shows it associated with blood letting, leeches were believed to restore balance to the body’s humors. In recent times, new experiments are being …
Published in Research & Reviews : Journal of Food Science & Technology · Vol. 15, Issue 1, 2026 · pp. 1–6 Read article
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Munzijate Balgham with Interpretation to Their Mechanism of Action in Stroke Rehabilitation: A Review
Abstract: The basic line of treatment of Falij Balghami is use of Munzijate Balgham followed by Mushilat and Muqawwiyat. Munzijat is the group of drugs which suitably modify the consistency of morbid Akhlat to make them able to evacuate from the tissues, vessels and interstitial spaces. They act either by liquefying the consistency of Ghaleez Akhlat, or by thickening the Raqeeq Akhlat. Nuzj occurs over a period of time which varies …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 4, Issue 3, 2015 · pp. 9–15 Read article
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Pharmacological, Characterization and Utilization of Ginger
Abstract: Ginger also known as Zingiber is the most important species used here, as India is the largest producer of it. Rhizome is the most important part of this plant which is used, having 50% carbohydrates, 6–8% free fatty acids and volatile oils like palmitic, oleic, linoleic acids as well as oleo resins, other amino acids and proteins. It is most important flavouring agent which is used worldwide. Ginger has many …
Published in Research and Reviews: A Journal of Health Professions · Vol. 13, Issue 2, 2023 · pp. 27–30 Read article
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Leech Therapy: A Therapeutic GEM
Abstract: Leech, Genus Hirudo, and therapeutics species: Hirudo medicinalis is an amphibious worm, 10 cm in length and is usually black or brown in color. It has three jaws with about 100 tiny teeth and a posterior sucker. The leech’s salivary secretions contain many bioactive chemicals, among which the most potent is Hirudin. The therapy involves bite by the leech, followed by attachment for duration of 15 to 45 minutes. The …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 12, Issue 1, 2024 · pp. 27–30 Read article
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Acute Ischemic Stroke: Diagnosis and Management Approach
Abstract: Stroke is the next chief reason of death worldwide and the foremost reason of debility, with a growing occurrence in emerging countries. Ischemic stroke produced by arterial obstruction is accountable for the majority of strokes. Management focuses on fast reperfusion with endovascular thrombectomy and intravenous thrombolysis, which together decreases debility but are time grave. The important primary stage in stroke maintenance is initial identification of patients with stroke and triage …
Published in Research and Reviews: A Journal of Neuroscience · Vol. 10, Issue 3, 2020 · pp. 25–46 Read article
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A Novel Method for Isolation of Plumbagin
Abstract: Normal 0 false false false EN-US X-NONE X-NONE MicrosoftInternetExplorer4 /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-qformat:yes; mso-style-parent:""; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-para-margin:0in; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:minor-fareast; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi;} The Plumbagin (5-hydroxy-2-methyl-1, 4-naphthoquinone) is the characteristic naphthoquinone present in the different species of the plant Plumbago (Family: Plumbaginaceae) commonly known as Chitrak in India. Plumbagin is …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 1, Issue 2, 2011 · pp. 1–6 Read article
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Role of Enoxaparin in the Management of STEMI: An Indian Perspective
Abstract: Cardiovascular diseases are major causes of morbidity and mortality worldwide. Acute coronary syndrome is one of the main causes of hospital admissions. ST-elevation myocardial infarction is the severe dreaded ACS causing morbidity and mortality. Probably because of economic reasons, conventional heparin continues to be the main anticoagulant therapy in STEMI. Enoxaparin is safe and effective in the treatment of ST-elevation myocardial infarction. Various studies outline its efficacy and safety in …
Published in Research and Reviews: A Journal of Medicine · Vol. 2, Issue 1, 2012 · pp. 15–20 Read article