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116 articles for “Anti-viral”
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Nigella Sativa Can Act as a Protective Agent to Fight Against Covid-19: An Update
Abstract: The severe acute respiratory syndrome coronavirus 2 (SARS CoV-2) causes Coronavirus Disease-19 (COVID-19), which began in Wuhan, Hubei Province, China and has since spread around the world. There are currently no effective antiviral medicines authorised for these coronavirus strains. Chloroquine, hydroxychloroquine, lopinavir/ritonavir, ribavirin, remdesivir, favipiravir, umifenovir, interferon-α, interferon-β, and other drugs are used to treat COVID19. There is no specific, effective, or proven conventional treatment to treat COVID-19 patients. As …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 9, Issue 1, 2022 · pp. 13–18 Read article
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Overcoming Obstacles to an HIV-1 Cure: Advances in Genome Editing, Immune System Reprogramming, and Viral Reservoir Elimination
Abstract: Human immunodeficiency virus type-1 (HIV-1) continues to represent a major global health challenge despite the remarkable success of antiretroviral therapy (ART). Although ART effectively suppresses viral replication and prolongs survival, it cannot eradicate the virus due to the persistence of long-lived latent reservoirs. In recent years, innovative therapeutic strategies have been explored with the aim of achieving either a functional remission or complete viral elimination. Advances in genome-editing technologies, particularly …
Published in International Journal of Virus Studies · Vol. 3, Issue 2, 2026 Read article
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Development of an Innovative Nanotransdermal Formulation Utilizing an Optimal Combination of Acyclovir and Omeprazole to Improve Antiviral Efficacy
Abstract: The study effectively created nanogel formulations of Acyclovir and Omeprazole using the solvent diffusion technique. Among the various formulations (F1–F9), F9 was identified as the most suitable for gel preparation based on its pH evaluation. Drug content analysis, performed using UV-spectroscopy, confirmed the homogeneity of the prepared nanogels, which appeared opaque, free of lumps, particles, or aggregates. The spreadability assessment of F9 demonstrated excellent spreadability, while viscosity values for all …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 2, Issue 1, 2024 · pp. 19–35 Read article
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Development of a Novel Therapeutic Approach Using RNA Interference for Targeting Viral Genes
Abstract: RNA interference (RNAi) is a ground breaking therapeutic strategy that holds immense promise for targeting viral genes in the treatment of viral infections. This approach leverages the natural gene-silencing mechanisms of RNAi to inhibit viral replication and expression at the molecular level, providing a precise and adaptable method to counteract viral pathogens, including influenza, HIV, and hepatitis viruses. Recent advancements in RNAi technology have enabled the development of highly specific …
Published in International Journal of Virus Studies · Vol. 1, Issue 2, 2024 · pp. 12–22 Read article
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Investigating the Impact of Viral Infections on Pharmacokinetics and Pharmacodynamics of Antiviral Drugs
Abstract: The emergence and re-emergence of viral infections pose significant challenges to public health, necessitating a comprehensive understanding of how these infections impact the pharmacokinetics and pharmacodynamics of antiviral drugs. This review explores the intricate interactions between viral pathophysiology and the pharmacological effects of antiviral agents. Factors such as viral replication dynamics, host immune responses, and the genetic variability of both viruses and hosts significantly influence drug absorption, distribution, metabolism, and …
Published in International Journal of Virus Studies · Vol. 1, Issue 2, 2024 · pp. 23–30 Read article
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Azadirachta Indica: A herbal Panacea in Dentistry– An Update
Abstract: Azadirachta indica better known as Neem, an evergreen tree. It has long been used by the people of India for the treatment of various ailments because of its medicinal properties. It has anti-bacterial, anti-cariogenic, anti-helminthic, anti-diabetic, antioxidant, astringent, anti-viral, cytotoxic, and anti- inflammatory activity. Nimbidin, Azadirachtin and nimbinin are active compounds present in Neem that are responsible for their anti-viral activity. Neem bark is used as an active ingredient in …
Published in Research and Reviews: A Journal of Dentistry · Vol. 14, Issue 4, 2023 · pp. 1–5 Read article
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Azadirachta Indica: A herbal Panacea in Dentistry–An Update
Abstract: Azadirachta indica better known as Neem, an evergreen tree. It has long been used by the people of India for the treatment of various ailments because of its medicinal properties. It has anti-bacterial, anti-cariogenic, anti-helminthic, anti-diabetic, antioxidant, astringent, anti-viral, cytotoxic, and anti-inflammatory activity. Nimbidin, Azadirachtin and nimbinin are active compounds present in Neem that are responsible for their anti-viral activity. Neem bark is used as an active ingredient in a …
Published in Research and Reviews: A Journal of Dentistry · Vol. 12, Issue 3, 2021 · pp. 1–5 Read article
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A Concentrated Review of Current Developments in the Diagnosis and Treatment of Viral Mumps
Abstract: Viral mumps, caused by the mumps virus, continues to pose public health challenges globally despite the availability of vaccines. Considerable advancements have been achieved in the last few years about the pathophysiology, diagnosis, and management of viral mumps. This focused review aims to highlight the latest advances in the diagnosis and treatment of viral mumps, with a particular emphasis on innovative strategies and emerging therapies. Key topics covered include the …
Published in International Journal of Tropical Medicines · Vol. 1, Issue 1, 2024 · pp. 01–07 Read article
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Extraction, Isolation, Characterization of Curcumin-I From Curcuminoids
Abstract: The major goal of this study is to extract, isolate, and characterize curcumin-I, a component of curcuminoids. Turmeric, or Curcuma longa Linn., plays a significant role in Ayurvedic medicine. Turmeric, or Curcuma longa Linn, is the popular name for this plant. An array of chemicals with biological activity may be more easily extracted with the help of this seasoning. Some of the compounds at play include curcuminoids and turmerone, although …
Published in Journal of Polymer & Composites · Vol. 10, Issue 4, 2022 Read article
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Hidden Gems of Dragon Fruit: Its Role in Pharmacognosy and Therapeutics
Abstract: The Cactaceae family includes the medicinal plant Hylocereus spp., also known as dragon fruit. The skin’s unique morphology, which reflects the body’s oval form, is characteristic of dragon fruit. Dry conditions are ideal for dragon fruit growth. Dragon fruit, also known as pitaya, is a fantastic functional food that has attracted attention recently due to its numerous therapeutic benefits, including antioxidant, anti-cancer, anti-diabetic, anti-microbial, hepatoprotective, and anti-hyperlipidemic properties. It also …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 12, Issue 1, 2025 · pp. 92–101 Read article
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Anthocyanin: Structure, Synthesis and its Beneficial Role in Health
Abstract: Anthocyanins, are chemically diverse class of secondary metabolites that color most flowers and fruits. They consist of three aromatic rings that can be substituted with hydroxyl, sugar, acyl and methyl groups in a variety of patterns, depending on the plant species. There are basically six types of anthocyanins commonly found in plants. The biosynthesis of anthocyanins start with the pentose-phosphate pathway, continues with shikimate pathway, and follows the pathway of …
Published in Research & Reviews : Journal of Food Science & Technology · Vol. 5, Issue 1, 2016 · pp. 45–55 Read article
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The Therapeutic Repertoire of Turmeric
Abstract: ABSTRACTTurmeric has been used in the treatment of arthritis, and other inflammatory conditions, for ages. Its healing constituent, curcumin, has been found to curb the incendiary activity of the COX-2 and lipooxygenase, the two enzymes involved in elevating and sustaining inflammation. It is also suggested that curcumin has a protective effect on the liver, thanks to its anti-tumour resolve, aside from its ability to easing inflammation and combating infections. This …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 5, Issue 2, 2018 · pp. 1–9 Read article
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Bergenin: Review of The Methods of Determination and Quantification
Abstract: Studies have shown that Bergenin has various pharmacological functions, such as Anti-lithiatic, Anti-oxidant, anti-inflammatory, Anti-bacterial, Anti-viral, Anti-cancer, Anti-cholinesterase, Anti-diabetic, Hypolipidemic, Anti-tussive, Hepatoprotective and Immunomodulatory. Bergenin is found in the Saxifragaceae, Euphorbiaceae, Myrsinaceae, Dipterocarpaceae, and Fabaceae genera and a range of beneficial effects on human health. The number of bioactive compounds in various bergenia species must be determined in order to achieve the best quality raw material for herbal preparations. As …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 8, Issue 2, 2023 · pp. 52–66 Read article
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Design, Synthesis and Pharmacological Evaluation of Pyrazoline Substituted Benzimidazole Derivatives as Antibacterial and Antifungal Agents
Abstract: Background: Benzimidazoles are important heterocyclic compounds possessing a variety of biological activities such as anticancer, antioxidant, antiinflammatory, analgesic, anti-viral, anti-bacterial, anti-fungal and hypoglycemic activities. Pyrazolines are used as antitumor, immunosuppressive, antibacterial and anti tubercular agents. Aim : The present research focused on incorporating pyrazoline nucleus into benzimidazole nucleus to form a potent antibacterial and antifungal agent. Method: The in silico design of novel pyrazoline substituted benzimidazole derivatives was done using …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 11, Issue 3, 2020 · pp. 29–41 Read article
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Advancements in Antiviral Therapeutics: Strategies and Challenges in the Development of Drugs and Vaccines for Viral Diseases
Abstract: Viral infections continue to pose a significant threat to global health, leading to high rates of illness, death, and economic burden. The constantly evolving nature of viruses, along with the rise of drug-resistant strains, underscores the need for continuous advancements in antiviral treatments. This review highlights the pivotal role of antiviral drugs and vaccines in mitigating the impact of viral infections, showcasing recent breakthroughs and exploring emerging technologies. Key advancements …
Published in International Journal of Virus Studies · Vol. 1, Issue 1, 2024 · pp. 32–36 Read article
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Empirical Relation to Predict Essential Oil Yield in Conventional Distillation System
Abstract: Peppermint is medicinal herb, and its extracts (essential oils) are of great importance because they are used in pharmaceutical, food, and cosmetic items. Moreover, peppermint oil is also used as anticancer, anti-bacterial, anti-viral, spasmodic, anti-diabetic, ulcer healing, anti-obesity, etc. Steam distillation method is used to extract essential oil from peppermint. Boiler, extraction unit, condenser and Florentine flask are the main components of steam distillation system. The objective of present study …
Published in Journal of Polymer & Composites · Vol. 11, Issue 14, 2023 Read article
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A Review on Different Species of Echinacea
Abstract: Echinacea is one of the plant species found in the North American tribes, which are commonly called as coneflowers. Echinacea species such as Echinacea angustifolia, Echinacea pallida, Echinacea purpurea, Echinacea serotina, etc. are used in the treatment of common cold, urinary tract infections, respiratory problems, etc. They also show anti-immunosupperssant activity, anti-viral activity, antifungal activity, anti-inflammatory activity, antioxidant activity, etc. This article mainly includes morphological features, chemical constituents, pharmacology, and …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 6, Issue 1, 2019 · pp. 1–6 Read article
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Anti-Escherichia coli Potentials of a Novel Chemical Compound 1-(2-hydroxy-1, 2-diphenylethylidene)-3-phenylthiourea
Abstract: Inspiration from the anti-infective excellence (anti-bacterial, anti-fungal, anti-viral, and anti-malarial) of Schiff’s base molecules as well as knowing the rising importance of low-molecular-weight ligands (LMWL), the present research involved the development of novel Schiff’s base compound utilizing very basic laboratory components; 1-phenylthiourea and benzoin using the conventional synthesis technique. The compounds were comprehensively characterized through sophisticated instruments and further screened for anti-microbial activity against pathogenic Escherichia coli (E. coli, MTCC …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 11, Issue 1, 2020 · pp. 9–12 Read article
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Uncovering the Comparative Efficacy of Antiviral Drugs and Caricapapaya Phytocompound as VP2H inhibitors in Ebola virus: An Insilico Molecular Docking Analysis
Abstract: The Ebola virus is a fatal disease that transmits from wild animals to humans. Infected individuals' body fluids such as spit, blood, perspiration, faeces, blood, saliva, breast milk, sperm, or fomites can transmit Ebola. Adhesion to cell membranes and penetration into the host organism are essential aspects in viral growth. The presence of VP24, as well as nucleoproteins and structural proteins, is necessary for nucleocapsid formation and integration. The inhibition …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 1, Issue 2, 2023 · pp. 62–78 Read article
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Uses of Nanotechnology in Medical Diagnostic Applications
Abstract: Nanoparticle and nanodevice is a boon for mankind to treat and deal with disease and medical diagnosis respectively. Nanotechnology is formed by the unity of chemistry, engineering, biology and medicine restricted to the nanoscale (about 1–100 nanometer (nm)). For example, early detection of malignant tumors and cancer biomarkers, which is impossible using conventional technologies. In here we will discuss nanosized sensors to identify different pathological parameters, foreign antigen and toxic …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 11, Issue 4, 2022 · pp. 25–29 Read article