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511 articles for “Anti – infective”
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Study of Price Variation of Anti-infective Eye Preparations
Abstract: To analyze the percentage cost variations among different brands of commonly prescribed ophthalmic drugs. The cost of different brands of commonly used ophthalmic drugs was sorted out by referring the latest Current Index of Medical Specialities, Indian Drug Review and Retail drug store. The cost of five dosage forms in INR of each brand, cost ratio and percentage cost variation ware calculated. Our study findings showed a very high fluctuation …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 5, Issue 2, 2018 · pp. 10–12 Read article
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Review of Mercaptoimidazoles as Anti-infective Agents
Abstract: 2-Mercaptoimidazole or imidazol-2-thione is five-membered heterocyclic ring having two nitrogen, same as imidazole and sulphur group attached to it at 2nd position. Imidazol-2-thione and its derivatives shows the biological activities such as antibacterial, fungicidal, antioxidant, antitumor, and antitubercular. In this review we have collected information about the 2-Mercaptoimidazole nucleus and its antimicrobial activity for further research and development.
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 9, Issue 1, 2022 · pp. 41–48 Read article
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Anti-infective Investigations of Methanolic Extract and Petroleum Ether Extract of Ixora coccinea L. Flowers
Abstract: Ixora is an evergreen flowering tropical plant belonging to the family Rubiaceae. It is commonly found in India, the United States of America, Africa, South East Asia, and Southern Asia. Across the globe, several species (Ixora coccinea, I. parviflora, I. chinensis, I. macrothyrsa, I. javanica, and I. finlaysoniana) of this genus have been identified so far. After going through the literature available in pharmaceutical databases, it was found that the …
Published in Research & Reviews : Journal of Botany · Vol. 9, Issue 2, 2020 · pp. 17–23 Read article
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Synthesis, Antibacterial Evaluation and Antifungal Study of New Biochemical Derivatives
Abstract: Bacterial and fungal infections have become widespread recently due to the spread of epidemics, diseases, and bacterial infections. As a result, infection rates have increased, prompting many researchers to develop new antibiotics to reduce the spread of these prevalent diseases. Researchers have prepared biochemical compounds similar in structure to drugs that eliminate infections and reduce their spread. One such derivative is imidazole; a well-known compound used in many medications for …
Published in Recent Trends in Infectious Diseases · Vol. 3, Issue 1, 2026 · pp. 19–28 Read article
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A Need of a Novel Antimicrobial Suture for Surgical Site Infection
Abstract: Surgical site infections post-surgery are the major complications that lead to the patient’s longer hospitalization which directly increases treatment cost. Triclosan is an antibacterial agent which has been used in coating surgical sutures to prevent infection post-surgery. Triclosan is being used since many years in many consumer products; the bacterial strains which are emerging these days may slow down or get resistance of their effects which might lead to the …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 6, Issue 3, 2016 · pp. 1–4 Read article
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Impact of Therapeutics on Carbapenem-Resistant Acinetobacter baumannii
Abstract: Acinetobacter baumannii, a formidable pathogen in healthcare settings, poses a significant threat due to its propensity to cause nosocomial infections. This bacterium exhibits several attributes that enable it to evade the human body's natural defenses. A. baumannii's remarkable adaptability is highlighted by its ease in acquiring antibiotic resistance determinants, rendering it challenging to treat. Its ability to thrive in hospital environments underscores the urgent need for stringent infection control practices …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 14, Issue 2, 2024 · pp. 1–11 Read article
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Benzimidic Acid Derivatives as Potential Anti-Escherichia coli Agent for Preventing Nosocomial Infections
Abstract: Based on the global fame of benzimidic acid/benzoic acid derivatives in exhibiting antimicrobial activities against a variety of pathogens (particularly nosocomial infections), two novel compounds (S1 and S2) of benzimidic acid scaffold were rationally designed from a hydrazine derivative and fabricated using the conventional synthesis technique. Through sophisticated instruments, the molecules were comprehensively characterized and investigated for antibacterial activity against pathogenic Escherichia coli strain (MTCC 2961). The novel benzimidic compound …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 9, Issue 1, 2020 · pp. 11–15 Read article
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Aloe vera: A Review on Its Medicinal Importance
Abstract: Today, one of the main causes of human infection is the antibiotic resistance of bacteria due to the use of antibiotics which causes the emergence and spread of antibiotic-resistant bacterial strains. The search for the discovery of healthy and effective antimicrobial agents continues. Aloe vera can be used for both therapeutic and preventive purposes in the case of a broad range of bacterial infections. Aloe vera is a medicinal plant …
Published in Research and Reviews : Journal of Crop science and Technology · pp. 1–5 Read article
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The Development and Assessment of a Polyherbal Powder Formulation for the Treatment of Fungal Infections
Abstract: A poly-herbal powder drink was made in the current investigation utilizing a variety of conventional herbs that have been shown to have nutritional benefits. Tinosopra cordifolia, Cinnamomum verum, Zingiber officinale, Thymus sperpyllum, and menthe were chosen as the main components because they are commonly used in summer home routines and have a long history of providing a refreshing, cooling, and energizing effect. Following several tests, the final formulation's composition was …
Published in Research & Reviews : Journal of Herbal Science · Vol. 11, Issue 3, 2022 · pp. 1–21 Read article
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Prevalence of Urinary Tract Infection among Suspected Female Patients Attending Manipal Teaching Hospital, Pokhara, Nepal
Abstract: Urinary tract infection (UTI) is a serious health problem affecting millions of people, commonly females, each year around the world. UTI is defined by a combination of clinical features or symptoms and the presence of bacteria in urine or presence of more than 100,000 CFU/mL after urine culture. Clinical symptoms of UTI include frequency, dysuria, abdominal pain, back pain, fever, and urgency. Diagnosis of UTI relies on both urinalysis and …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 3, Issue 2, 2013 · pp. 20–32 Read article
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Assessment Of Prescription Pattern Of Antibiotics In Geriatric Population At Tertiary Hospital
Abstract: Antibiotics is an anti-infective agent that are capable of Destroying and inhibiting the growth of micro-organisms and it is derived from Bacteria or Moulds that are toxic to other bacteria. Alexander Fleming in1928,accidently discovered Penicillin notatum . he found that penicillin notatum are extremely effective even at very low concentration. In elder population Aging process causes changes in nervous system, cognition , vision , hearing , memory, learning , intelligence …
Published in Trends in Drug Delivery · Vol. 10, Issue 2, 2023 · pp. 11–15 Read article
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A Study and Report on Role And Impact Of Clinical Pharmacist in assessment of Prescribing Cascades In Antibiotics Usage For Infectious Diseases in Promotion of Rational Drug Usage
Abstract: ABSTRACT:A Prescription cascade occur when the healthcare providers fail to recognise that the new symptoms are actually the side effects of the medications under treatment. The study was based on the role and impact of clinical pharmacist in assessment of prescribing cascades in antibiotics usage for infectious diseases in department of general medicines and paediatric department at ESI hospital, Indiranagar, Bangalore, Karnataka, India. The main motto of the study was …
Published in Research & Reviews: A Journal of Drug Formulation, Development and Production · Vol. 9, Issue 3, 2022 · pp. 1–14 Read article
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Ocular Films as a Drug Delivery System Against Fungal Infections: Current Insights and Future Directions
Abstract: Fungal infections of the eye, including keratitis, endophthalmitis, and blepharitis, represent a challenging class of ocular diseases due to their potential for vision loss and the limited efficacy of existing treatments. These infections are caused by a range of pathogenic fungi, such as Aspergillus, Candida, and Fusarium species, and often require long-term therapeutic intervention. Conventional topical antifungal therapies, such as eye drops and ointments, suffer from poor ocular bioavailability due …
Published in Trends in Drug Delivery · Vol. 12, Issue 2, 2025 · pp. 101–109 Read article
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Emerging Therapies in Respiratory Tract Infections: Current Advances and Future Perspectives
Abstract: The impact of respiratory tract infections (RTI) as a global public health problem continues to be high morbidity and mortality rates. The development of novel therapeutic approaches stemmed from the fact that conventional treatment strategies, antibiotics, antivirals, antifungals etc. have become increasingly ineffective because of rise of antimicrobial resistance (AMR). Next generation therapies, such as novel antimicrobial agents, host directed therapies and novel drug delivery systems have come on the …
Published in Recent Trends in Infectious Diseases · Vol. 2, Issue 2, 2025 · pp. 17–25 Read article
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Knowledge, Attitude & Practices of Hepatitis B Infection and Serum Antibody Analysis among Hepatitis B Vaccinated Healthcare Workers in Tertiary Care Hospital in North India
Abstract: Introduction: Health care workers are particularly at high risk of acquiring Hepatitis B virus (HBV) and other infections through needle stick injuries (NSI). HBV transmission can be contained through vaccination among health care workers (HCWs). However, 10-15% individuals have poor response. This study was therefore done to assess knowledge, attitude and practices (KAP) and to evaluate the anti-HBs antibody titres in HBV vaccinated HCWs in tertiary care hospital. Material and …
Published in Research and Reviews : A Journal of Immunology · Vol. 10, Issue 2, 2020 · pp. 25–30 Read article
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Evaluation of Respiratory Tract Infectious Pathogens and Their Antibiotic Sensitivity in a South Indian Hospital
Abstract: This study is aimed to determine prevalence of infectious agents causing respiratory tract infection (RTIs) and their sensitivity to antibiotics. The study was conducted in Rajiv Gandhi Institute of Medical Sciences of Kadapa in Andhra Pradesh in South India from December 2013 to May 2014. Patients who were clinically suspected of RTIs were included in the study. Sputum, throat swab and pleural fluid samples were collected aseptically from the patients …
Published in Research and Reviews: A Journal of Medicine · Vol. 4, Issue 3, 2014 · pp. 18–25 Read article
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THE BURDEN OF EMPIRICAL THERAPY: ANALYZING THE PREDOMINANCE OF BROAD-SPECTRUM ANTIBIOTIC USAGE IN LOWER RESPIRATORY TRACT INFECTIONS
Abstract: Lower respiratory tract infections (LRTIs) remain one of the leading causes of morbidity and hospitalization worldwide, particularly among older adults, immunocompromised individuals, and patients with chronic respiratory disorders. These infections include conditions such as community-acquired pneumonia, hospital-acquired pneumonia, bronchitis, and acute infective exacerbations of chronic lung disease, all of which often require rapid clinical intervention. Because microbiological confirmation of the causative pathogen frequently takes 48–72 hours, clinicians generally initiate empirical …
Published in International Journal of Antibiotics · Vol. 3, Issue 2, 2026 Read article
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Evaluation of Rational Use of Antibiotics and Incidence of Surgical Site Infections in a Tertiary Care Hospital
Abstract: Context: Antimicrobial resistance is a major health issue nowadays. It can be reduced by framing, educating health care professionals, strictly following and reviewing the guidelines for antibiotics usage. Many hospitals are not following standard guidelines for antibiotics usage which has led to overuse of antibiotics which contributes for the emergence of resistant strains of microbes against antibiotics. Antibiotics are used pre-operatively to reduce the risk of surgical site infections. The …
Published in Research and Reviews : Journal of Surgery · Vol. 7, Issue 3, 2018 · pp. 4–8 Read article
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Bacteriological Profile and Antibiogram Pattern in Lower Respiratory Tract Infection in Kota Region (Raj)
Abstract: Lower respiratory tract infections are the most frequent infections among patients. The consequences on increased drug resistance are far reaching, since bacterial infection of the lower respiratory tract is a major cause of death from infections disease. This study was focused on obtaining a comprehensive insight into the microbial profile, its prevalence and the antibiotic susceptibility patterns of the isolates in lower respiratory tract infections. Sputum specimens were collected from …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 6, Issue 2, 2016 · pp. 13–17 Read article
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A Study and Report on Assessment of Antibiotic Prescribing Patterns and Drug Resistance Among Various Infectious Diseases in Hospital
Abstract: Antimicrobial resistance remains the biggest cause of death worldwide. According to the World Health Organization, the age standardized mortality due to infectious diseases in India in 2008 was 377 per 100,000 persons, which is considered as highest in South Asia. This has led to the increased prescribing of antibiotics even at unnecessary conditions, which increased the rate of inappropriate prescribing of antibiotics, which in turn resulted in the emergence of …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 10, Issue 2, 2021 · pp. 5–35 Read article