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571 articles for “therapeutic uses”
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Optimization of Resin 3D Printing Process Parameters for Enhanced Dimensional Accuracy and Surface Roughness Using Hybrid Algorithm
Abstract: The advent of 3D printable dental resin has paved the way for minimally invasive dentistry, which helps to retain healthy tooth structure while yet producing pleasing aesthetic outcomes. However, printing these dental resins is being researched to improve their durability and therapeutic efficacy. Frontiers in dental restoration research can aim to fabricate occlusal appliances using resins with optimized parameters for enhanced functionalities. The present study aims to analyze the dimensional …
Published in Journal of Polymer & Composites · Vol. 11, Issue 3, 2023 · pp. 26–37 Read article
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A Comparative Review on Abelmoschus palianus and Barleria mysorensis: Phytochemical Constituents, Pharmacological Potentials, and Ethnobotanical Significance
Abstract: Medicinal plants have long served as invaluable resources for treating human ailments, with countless species still awaiting scientific exploration and validation. Abelmoschus palianus and Barleria mysorensis are two such botanicals with rich ethnomedicinal heritage but limited pharmacological characterization. This review presents a detailed comparative analysis of these two species, examining their botanical descriptions, geographic distribution, traditional applications, phytochemical constituents, pharmacological properties, toxicological profiles, and therapeutic potential. Abelmoschus palianus, native to …
Published in Research & Reviews : Journal of Herbal Science · Vol. 14, Issue 3, 2025 · pp. 7–13 Read article
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Bioactive Compounds in Ethanolic Extract of Strychnos innocua Root Using Gas Chromatography and Mass Spectrometry (GC-MS)
Abstract: Medicinal plants are of great relevance with endless pharmaceutical and therapeutic properties. They are source of wide array of secondary metabolites or bioactive compounds/phytochemicals (phenols, alkaloids, flavonoids, terpenoids, tannins, steroids and saponins) which can discharge numerous biological functions (antimicrobial, antioxidant, antiviral, antifungal, anti-fibrotic, immune-modulatory, cytotoxic, antipyretic, antitumor, antihelminthic, antiprotozoal, antibacterial, and so on). The use of gas chromatography and mass spectrometry analysis in identifying the bioactive compounds in the ethanolic …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 1, Issue 1, 2023 · pp. 9–14 Read article
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Alzheimer disorders diagnosis system design using machine learning for EEG signal
Abstract: The diagnosis of Alzheimer's disorders (AD), a prevalent neurological disorder, can created by utilising a range of therapeutic methods, including the electroencephalogram (EEG), which has been especially successful in the past. The objective for this study is to develop a computer-aided diagnosis tool which may recognize AD from EEG data. The EEG information was cleaned up with a band-pass elliptic digital filter to remove any interference or disruptions. The filtered …
Published in Journal of Control & Instrumentation Read article
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Exploring the Role of Ginkgo biloba in Investigating 7L1X in Triple-Negative Breast Cancer Through Integrative Bioinformatics
Abstract: Objectives: Triple-negative breast cancer is a very dangerous form of cancer that affects mostly Hispanic and African American women above the age of 40. It represents approximately 15–20% of the global cancer incidence. This experiment aims to investigate the use of Gingko biloba in the treatment of the disease triple-negative breast cancer. Methods: We use a variety of online tools, and websites, including the Indian Medicinal Plants, Phytochemistry, and Therapeutics …
Published in International Journal of Bioinformatics and Computational Biology · Vol. 2, Issue 2, 2024 · pp. 1–10 Read article
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Encapsulation of Karela Extract in Polymer Nanoparticles
Abstract: Karela (Momordica charantia) fruit extract possesses promising antibacterial properties. However, its direct application can be limited by factors like degradation and uncontrolled release. This study explores the encapsulation of Karela extract within biocompatible and biodegradable polymeric nanoparticles as a potential strategy to enhance its efficacy. The research investigates the development of nanoparticle systems using various polymers and their impact on the stability, controlled release, and antibacterial activity of the encapsulated …
Published in Journal of Polymer & Composites · Vol. 13, Issue 1, 2025 · pp. 864–867 Read article
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A Review on Therapeutic Utilities and Purificatory Procedure of Gunja (Abrus precatorius Linn.) as Described in Ayurveda
Abstract: AbstractGunja (Abrus precatorius Linn.), belonging to the family Fabaceae, has been used by the Ayurvedic physicians, for management of different disease conditions. It comes under the upavisha (semi-poisonous) group in Ayurvedic pharmacopoeia. It is a slender, perennialclimber with long, pinnate leaves that twines around trees, shrubs and hedges. In this review, an endeavour has been made to explore the therapeutic utilities of Gunja, its formulations and its different methods of …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 2, Issue 1, 2013 · pp. 1–11 Read article
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In Silico Molecular Docking of Indigofera tinctoria Phytocompounds to Target EGFR/ERK and FGFR/FGF Pathway Proteins Involved in Prostate Cancer
Abstract: Objective: Prostate cancer being the second major cause of cancer-related deaths in males, affects the small walnut-shaped gland below the bladder called the prostate gland. The epidermal growth factor protein (EGFR), cascade protein (ERK), and fibroblast growth factor proteins (FGFR and FGF) are involved in the different signaling pathways that lead to the formation of different products, that are responsible for the progression of cancer and thus can be considered …
Published in International Journal of Molecular Biotechnological Research · Vol. 1, Issue 1, 2023 · pp. 34–56 Read article
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Natural Cooling Agent: Utilizing Menthol as a Paraben-Free Preservative in Herbal Cosmetics
Abstract: The quest for natural and sustainable alternatives in cosmetic products has intensified, driving the search for effective natural preservatives. Menthol, derived from mint plants, is being recognized for its cooling properties and potential as a paraben-free preservative. This study investigates menthol’s efficacy as a preservative in herbal cosmetics, addressing consumer concerns about synthetic preservatives while ensuring product safety and longevity. This research examines menthol’s antimicrobial effects on common cosmetic contaminants …
Published in Research & Reviews: A Journal of Pharmacognosy · Vol. 11, Issue 3, 2024 · pp. 16–39 Read article
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A Combined Molecular Docking Analysis of The Phytochemicals of Ginkgo biloba against The Parkin Protein Target (Autoinhibited Parkin Catalytic Domain)
Abstract: This study's goal is to evaluate the specific therapeutic targets for Parkinson's disease (PDB ID: 4BM9) using molecular docking simulation and ADME analysis against bilobalide, quercetin, ginkgolide B, and protocatechuic acid (3,4-Dihydroxybenzoic acid). The Protein Data Base was used to extract theprotein's three-dimensional structure, and the PubChem database was used to retrieve the ligands. Using Auto-Dock Tools-1.5.7, a molecular docking simulation of the compounds was carried out. Since none of …
Published in Journal of Catalyst & Catalysis · Vol. 10, Issue 1, 2023 · pp. 1–9 Read article
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Computational Examination of Curcumin Derivatives as Promising Inhibitors for BRCA1 and BRCA2 Proteins in Breast Cancer Treatment
Abstract: Objective: Breast cancer is a major problem for global health and one of the most popular and dangerous diseases. Data from the National Cancer Registry Program (NCRP) of the National Center for Disease Informatics and Research (NCDIR), an arm of the Indian Council of Medical Research (ICMR) in Bangalore, India, shows that an estimated 1,461,427 new cancer cases will occur… Conditions in India by 2022. Among these conditions, breast cancer …
Published in Research and Reviews : Journal of Computational Biology · Vol. 12, Issue 3, 2023 · pp. 68–87 Read article
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Leech Therapy: A Therapeutic GEM
Abstract: Leech, Genus Hirudo, and therapeutics species: Hirudo medicinalis is an amphibious worm, 10 cm in length and is usually black or brown in color. It has three jaws with about 100 tiny teeth and a posterior sucker. The leech’s salivary secretions contain many bioactive chemicals, among which the most potent is Hirudin. The therapy involves bite by the leech, followed by attachment for duration of 15 to 45 minutes. The …
Published in Research and Reviews : A Journal of Medical Science and Technology · Vol. 12, Issue 1, 2024 · pp. 27–30 Read article
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Epigenetic Modifications in Health, Disease, and Precision Therapeutics (From Genome to Epigenome)
Abstract: Introduction: Epigenetic alterations play a crucial role in regulating gene expression in both normal physiological and disease states. These reversible modifications—such as DNA methylation, histone acetylation, phosphorylation, ubiquitination, and chromatin remodelling—are increasingly implicated in complex diseases including cancer and neurodegenerative disorders. Despite advances in standard therapeutic approaches, patient responses remain variable, largely due to genetic heterogeneity and epigenetic dysregulation. This highlights the need for incorporating epigenetic understanding into personalized medicine. …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 15, Issue 1, 2026 Read article
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Syndesis for the dislocation of the acromioclavicular joint with artificial tendon and therapeutic results.
Abstract: Background: Operation is applied for type 5 acromioclavicular joint dislocation on Rockwood’s classification. We think that use of the artificial tendon best restores the function of the acromioclavicular joint. We tried to correctly reconstruct the anatomy of the acromioclavicular ligaments and describe the treatmet using the artificial tendon.Materials and methods: There were 25 patients; mean age at surgery, 37.2 years. Mean time to surgery was 12.5 days. Mean follow-up was …
Published in Research and Reviews : Journal of Surgery · Vol. 12, Issue 1, 2023 · pp. 25–28 Read article
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Comparative Efficacy and Safety of Safinamide and Rasagiline in the Treatment of Parkinson’s Disease: A Meta-Analysis and Systematic Review
Abstract: Background: Recent studies have suggested Rasagiline and Safinamide monotherapy as potential management options for Parkinson’s disease. Parkinson’s disease, a neurological disorder characterized by tremors and movement difficulties, necessitates treatments aimed at managing clinical symptoms. Levodopa remains the primary effective treatment for Parkinson’s disease symptoms; however, its long-term use often leads to motor complications in many patients. Additional therapeutic drugs, such as dopamine agonists and monoamine oxidase B inhibitors, including Safinamide …
Published in Research and Reviews: A Journal of Pharmacology · Vol. 14, Issue 3, 2024 · pp. 74–91 Read article
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SIBR/Aloe barbadenis Mill.: A Review on Medicinal Utility from the Perspective of Unani Medicine
Abstract: Aloe barbadensis Mill., known as Sibr in Unani medicine, is a time-honored medicinal plant belonging to the family Liliaceae. Revered across cultures and healing systems, it has been extensively described in Unani literature under various names such as Elwa, Musabbar, and Ghikwar. This review aims to comprehensively explore the medicinal utility of Sibr from an Unani perspective while integrating evidence from modern pharmacognosy, phytochemistry, and pharmacology. Traditionally, the dried juice …
Published in Research & Reviews : A Journal of Unani, Siddha and Homeopathy · Vol. 12, Issue 3, 2025 · pp. 22–29 Read article
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Pharmacological Management of Behavior in Children
Abstract: This research work aims to review various drugs used for the management of behavior in children. Pharmacological management describes the use of various drugs to manage the behavior of pediatric patients undergoing dental procedures. Several types of drugs and routes of administration (e.g. oral, recta, intramuscular, intravenous etc.) have been tested to achieve this aim. The use of sedative drugs along with local anesthetics has shown to reduce anxiety and …
Published in Research and Reviews: A Journal of Dentistry · Vol. 11, Issue 1, 2020 · pp. 8–17 Read article
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Comprehensive Analysis of MRSA Peptides Via Maldi
Abstract: The present study employed Matrix-Assisted Laser Desorption/Ionization Time-of-Flight mass spectrometry to analyze methicillin-resistant Staphylococcus aureus peptides, focusing on various parameters associated with mass-to-charge (m/z) values. Through systematic data collection and analysis, including time, intensity, signal-to-noise ratios, quality factors, resolutions, areas under the peaks, relative intensities, full widths at half maximum, Chi-squared values, and background peaks, comprehensive insights into the spectral characteristics of methicillin-resistant Staphylococcus aureus peptides were obtained. Methicillin-resistant Staphylococcus …
Published in Research and Reviews: A Journal of Pharmaceutical Science · Vol. 15, Issue 2, 2024 · pp. 98–101 Read article
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Polymer Chemistry and Its Applications in Pharmaceutical Composite Formulations
Abstract: Polymer chemistry plays a critical role in pharmaceutical formulations, particularly in enhancing drug stability, bioavailability, and controlled release. Polymers are widely utilized in drug delivery systems. Polymers are widely used in pharmaceutical sciences for drug delivery, controlled release, and stability enhancement. This paper explores the role of polymers in the extraction and formulation of glycyrrhetinic acid from Glycyrrhiza glabra, a bioactive compound. Various polymer-based extraction and purification techniques are discussed, …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 216–221 Read article
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CB₁ Reverse Agonists: A Cheminformatic and Patent Landscape Study
Abstract: The endocannabinoid system plays a crucial role in numerous physiological functions, making cannabinoid receptor 1 (CB1) an attractive target for therapeutic development. This review provides a systematic analysis of patent filings from 2019 to 2023 that focus on small-molecule CB1 reverse agonists. It begins with an overview of the endocannabinoid system, highlighting CB1’s involvement in energy balance, pain regulation, and neuroinflammatory processes The main section of the review examines fifteen …
Published in International Journal of Cheminformatics · Vol. 3, Issue 2, 2025 · pp. 33–36 Read article