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1953 articles for “phosphoinositol-3-kinase pathway” (ranking capped at the first 2,000 matches — narrow the search to see the rest)
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Investigation on The Effect of Carbon Fiber Reinforcement on The Mechanical and Physical Properties of FDM 3d Printed PLA
Abstract: In this work, the effects of annealing on the physical properties and mechanical behavior of short-carbon-fiber-reinforced polylactic acid (CF/PLA) composites made using fused deposition modeling (FDM) are systematically investigated. Pristine PLA and CF/PLA composites with 10% fibers have been made and evaluated in accordance with ASTM standards. Tensile, bending, and hardness tests were used to evaluate the performance of as-received and annealed composites. The tensile and hardness properties of PLA …
Published in Journal of Polymer & Composites · Vol. 14, Issue 1, 2026 · pp. 284–298 Read article
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Photochemical Detoxification of Arsenic- and Mercury-Contaminated Soils: Geochemical Mechanisms and Pathways
Abstract: This study evaluates the geochemical aspects of soil detoxification in areas contaminated with arsenic (As) and mercury (Hg), emphasizing sustainable strategies for improving soil health and ensuring safe crop production. The research provides an ecological and toxicological assessment of regional soils and classifies them base on the concentration and mobility of toxic elements. Although the current levels of As and Hg do not yet present a critical risk to agricultural …
Published in International Journal of Photochemistry and Photochemical Research · Vol. 4, Issue 1, 2026 · pp. 06–10 Read article
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Genetic Counseling: A Pathway to Understanding and Managing Inherited Health Risks
Abstract: Genetic counseling is an essential aspect of personalized medicine that supports individuals and families in understanding the implications of inherited health conditions. With the rising prevalence of genetic disorders and advancements in genomic technologies, counseling provides critical insights into risk factors, diagnostic options, and informed decision-making. This paper explores the classification of genetic disorders, major genetic and environmental causes, and the expanding role of genetic counseling within India’s culturally diverse …
Published in International Journal of Evidence Based Nursing And Practices · Vol. 4, Issue 1, 2026 · pp. 10–14 Read article
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Analyzing The Mechanisms of Polymerization and The Related Kinetic Pathways Using Refined Analytical Methods.
Abstract: In numerous sectors, polymeric materials play a crucial role, yet effectiveness is largely determined by their molecular structure and the processing parameters utilized. This investigation presents an integrative approach aimed at delineating the connections between polymer structure, properties, and processing through sophisticated characterization methods. With the implementation of small angle X Ray Scattering (SAXS),NMR(Nuclear magnetic resonance( spectroscopy) FM(Atomic Force Microscopy) and rheological analysis, we analyze the complex interplay between molecular …
Published in Journal of Polymer & Composites · Vol. 13, Issue 2, 2025 · pp. 86–94 Read article
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Antifungal Susceptibility Pattern of Candida Species Isolates from Dehradun City Hospitals
Abstract: The present investigation on the topic entitled “Antifungal susceptibility analysis of Candida species isolates from Dehradun City hospital.” was accomplished in the Doon University Microbiology laboratory (P.G.) and Hospital, Dehradun, Uttarakhand, during the period of February 2021 to July 2021. A total of 42 clinical samples were collected from patients, suspected of candidiasis from Dehradun city hospitals. Clinical samples were collected from oral cavity, blood, vaginal fluid and urine of …
Published in Research and Reviews : A Journal of Immunology · Vol. 14, Issue 1, 2024 Read article
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Computer-aided Drug Design Method for Anti-hepatitis C Drug Design
Abstract: Hepatitis C is a disease caused by the hepatitis C virus and can cause serious liver damage. There is currently no vaccine for this disease and the number of infections continues to increase worldwide. Currently used antiviral drugs are interferon alfa-2a and ribavirin, but about half of patients do not respond to therapy. Therefore, new drugs that protect against hepatitis C need to be investigated. Computational drug methods have been …
Published in Research and Reviews : A Journal of Immunology · Vol. 14, Issue 2, 2024 · pp. 1–8 Read article
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Solid acidity of MoO3 synthesized by solution combustion method and acetalization of formaldehyde using it
Abstract: MoO 3 nanoparticles were synthesized via solution combustion approach. Ammonium nitrate was used as oxidant and ammonium molybdate as fuel in combustion reaction. XRD, FTIR and Raman spectroscopy results showed that MoO 3 nanoparticles were successfully synthesized by the solution combustion reaction. The SEM analysis showed that synthesized MoO 3 nanoparticles have rod-like shape with width and thickness of 50-200nm and length of 0.2-1μm, respectively. The XRD pattern and morphology …
Published in Journal of Catalyst & Catalysis · Vol. 12, Issue 3, 2025 · pp. 01–09 Read article
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In-Silico Screening of Phytochemicals for Identification of Alternative Therapy for Thyroid Cancer
Abstract: Thyroid cancer remains a significant health concern globally, necessitating the exploration of novel therapeutic alternatives to improve treatment outcomes. This study targets COT kinase (Cancer Osaka Thyroid Kinase), a protein implicated in the progression of thyroid cancer, using molecular docking methods with various phytochemicals to identify potential therapeutic compounds. PyRx and Discovery Studio were employed to evaluate the interactions and binding affinities of a diverse set of natural compounds with …
Published in International Journal of Toxins and Toxics · Vol. 2, Issue 2, 2025 · pp. 31–55 Read article
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Efficacy of New Fungicides in Controlling Powdery Mildew of Sweet Gourd
Abstract: This experiment was conducted at the Plant Pathology Division, Regional Agricultural Research Station (RARS), Jamalpur, Bangladesh during 2025 of Rabi & Kharif-1 seasons to find out the effectiveness of new fungicides against Powdery mildew disease of sweet gourd. Twenty (20) new fungicides viz. Acrozet 50 WP, Qingdao GBW, Hea 10 FC, Top star 32.5 SC, Nila 80 WP, Soazeb 72 WP, Safezeb 80 WP, Canvas 32.5 SC, Pyzim 50 WP, …
Published in Research & Reviews : Journal of Agricultural Science and Technology · Vol. 14, Issue 3, 2025 · pp. 134–142 Read article
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Comparative Analysis of the Structural Integrity and Dimensional Stability of Additively Manufactured Biopolymers vs. Thermoformed PETG: A 1-Year Retrospective Study on Polymer Performance in Orthodontic Applications
Abstract: Objective: This study aimed to evaluate the long-term dimensional accuracy and structural performance of direct 3D-printed biopolymers compared to conventional vacuum-formed Polyethylene Terephthalate Glycol (PETG) composites. The investigation focused on how different polymer processing methods (additive manufacturing vs. thermoforming) influence material thinning and resistance to occlusal stress. Methods: A retrospective analysis was conducted on 60 cases (n = 60) of post-orthodontic maintenance. The sample was divided into two cohorts: Group …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 140–146 Read article
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Quality Appraisal for the Ornamental Bird, Fish, Dog, and Cat Foods Available in Bangladesh
Abstract: The study aimed to assess if the chemical composition of different avian, aquatic, dog, and cat foods commonly available in Chattogram, Bangladesh adheres to the recommended standards. Food samples were collected and subjected to proximate analysis for the dry matter (DM), crude protein (CP), crude fibre (CF), ether extract (EE), nitrogen free extract (NFE), and total ash (TA). The plant seeds used for ornamental birds exhibited substantial variability in terms …
Published in Research and Reviews : Journal of Veterinary Science and Technology Read article
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Tribological Study on SiC+Graphene Reinforced Al319 Composite andOptimization of Stir Casting Parameters
Abstract: The aluminium 319 (Al319) is a commonly used material for fabricating automobile components. Due to continuous friction and vibration, those components are subjected to significant wear. Therefore, it is necessary to improve the wear characteristics of this Al319. Hence, in this study Silicon Carbide (SiC) and Graphene nanoparticles (GNPs) are reinforce to Al319 via electro-magnetic stir casting method to optimize wear characteristics without its affecting mechanical properties. Various proposition of …
Published in Journal of Polymer & Composites · Vol. 12, Issue 6, 2024 · pp. 105–123 Read article
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Influence of Inter and Intra-Row Spacing on Hot Pepper (Capsicum Annum L.) Growth,Yield and Yield Component of Under Rain Fed at Guraferda and Gimbo, Southwest Ethiopia
Abstract: Inappropriate plant population density and other limitation factors are among the key reasons for the low hot pepper yield in Ethiopia, including South West Ethiopia. To increase the productivity of hot pepper use of appropriate population spacing is vital. Hence, a field experiment was conducted at Guraferda and Gimbo during the main rainy season to evaluate the response of hot pepper for growth and yield and yield components. A factorial …
Published in International Journal of Trends in Horticulture · Vol. 1, Issue 1, 2024 · pp. 4–9 Read article
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Exploring The Therapeutical Potential Of Pongamia Pinnata For Herpes Simplex Virus Type 1 (HSV-1)
Abstract: Objective: Pongamia pinnata (L.), commonly known as Indian beech or pongam tree, is a tropical plant renowned for its medicinal properties in traditional medicine systems. Extracts derived from various parts of Pongamia pinnata have demonstrated antimicrobial, anti-inflammatory, and immunomodulatory activities. Such attributes make it a compelling candidate for exploring its therapeutic potential against HSV infections. Thymidine kinase is the target protein mostly used in the treatment of HSV1 infections. In …
Published in Research and Reviews: A Journal of Microbiology and Virology · Vol. 15, Issue 1, 2025 · pp. 1–9 Read article
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CRISPR-Cas9: Revolutionizing the Genetic Frontier
Abstract: The rapid development of CRISPR/CRISPR-associated enzyme (Cas) technology has enabled truly customised treatment of human genetic disorders, paving the way for recent developments in the field of gene therapy. Because CRISPR/Cas can accurately target and edit individual genes within a genome, it has established itself as a formidable tool for genetic manipulation. CRISPR/Cas9 technology allows for precise editing of specific DNA sequences in an organism's genome. This method uses three …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 3, Issue 2, 2025 Read article
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Design and Performance Evaluation of PLA-based Umbrella Wheels for Stair-Climbing Robotic Applications
Abstract: Staircase climbing robots require a complex design capable of navigating various stair configurations. A crucial component of such robots is the wheel mechanism. This paper focuses on the umbrella wheel mechanism and its application in staircase climbing robots. In this study, a PLA–based umbrella wheel structure is developed and fabricated using fused deposition modeling (FDM) for application in stair-climbing robots. The umbrella wheel geometry enables transformation from a circular rolling …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 808–824 Read article
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Nutrient Sensing and Microbiota Crosstalk: Driving Determinants Shaping Metabolic Stability and Adaptive Physiology for Animal Health
Abstract: Nutrient sensing is a fundamental cellular process that enables animals to adapt to fluctuating dietary inputs while maintaining metabolic homeostasis and health. Recent advances reveal that the gut microbiota functions as an active metabolic partner, producing bioactive metabolites that directly influence host nutrient-sensing pathways and downstream cellular responses. This review synthesizes current knowledge on the integration of key signalling networks, including adenosine monophosphate activated protein kinase (AMPK), mechanistic target of …
Published in International Journal of Molecular Biotechnological Research · Vol. 4, Issue 2, 2026 Read article
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In Silico Drug Design for Mycobacterium tuberculosis and Development of Host–Pathogen Interaction Network and Molecular Docking Procedures
Abstract: Objective: A leading cause of illness is the contagious disease tuberculosis (TB), this infection with Mycobacterium tuberculosis complex (MTBC) particularly M. tuberculosis and M. africanum, is what causes tuberculosis. Diverse receptor proteins (mycobacterial proteins) with various 3D structures and functions were evaluated to access the multi-domain antimycobacterial action of ligands. The specific receptor proteins PDB ID: 3PTY, PDB ID: 4OW8, PDB ID: 5KWA, and PDB ID: 3ZXR, were opted for …
Published in International Journal of Molecular Biotechnological Research · Vol. 1, Issue 1, 2023 · pp. 1–19 Read article
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A Comparative Study of Zinc Oxide Nano Particles Synthesized by Hydrothermal, Sol-gel and Thermal Decomposition
Abstract: In the proposed work, Zinc oxide nano particles (ZnO NP's) are synthesized using three different methods: Hydrothermal, Sol-gel and Thermal decomposition. The samples are characterized using X- ray diffraction (XRD), UV visible spectroscopy (UV-Vis), Fourier Transform Infrared Spectroscopy (FT-IR) and scanning electron microscopy (SEM). The XRD pattern exhibit single-phase polycrystalline nature of all the samples exhibiting the most intense peak at (101). The diffraction peaks are located at 31.80, 34.46, …
Published in Journal of Polymer & Composites · Vol. 11, Issue 7, 2023 · pp. 39–45 Read article
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Design and Development of Ankle Foot Orthosis for Foot Amputated Person by Using Carbon Fibre
Abstract: Ankle and foot orthotics play a pivotal role in the rehabilitation of individuals who have suffered a stroke, aiding in the restoration of their gait and overall mobility. However, optimizing the effectiveness of these orthoses requires a personalized approach that takes into account each patient's unique biomechanical characteristics. This study delves into the innovative use of carbon fiber combined with cost-effective 3-D printing technology to craft custom foot plate orthoses …
Published in Journal of Polymer & Composites · Vol. 11, Issue 8, 2023 · pp. 115–121 Read article