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182 articles for “Formulation Optimization”
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Review on Sustained Released Matrix Tablet
Abstract: Pharmaceuticals often use sustained release dose forms to prolong the therapeutic agent’s presence in the bloodstream and maintain a consistent plasma profile. The matrix governs the drug’s release rate. Hydroxypropyl methyl cellulose, a release retardant, is a key excipient in formulations due to its ability to promote sustained release. Techniques that include wet granulation, direct compression, or the dispersion of solid particles within a porous matrix, integrating polymers, like polymethyl …
Published in Trends in Drug Delivery · Vol. 12, Issue 2, 2025 · pp. 60–69 Read article
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The Role of Precision Agriculture in Enhancing Horticultural Crop Yields
Abstract: This article explores the quantification of lithium and mapping of mineral composition in crushed lithium ore utilizing two distinct calibration techniques with Laser-Induced Breakdown Spectroscopy (LIBS). Thirty samples from a pegmatite lithium deposit were analyzed, with representative mineral samples extracted, mixed with resin, and polished into disks. These disks underwent examination via an analyzer and an integrated mineral analyzer, facilitating mineral identification. The first calibration technique used empirical mineral chemistry …
Published in International Journal of Trends in Horticulture · Vol. 1, Issue 1, 2024 · pp. 18–23 Read article
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A Critical Review of Gandhaka & Its Shodhan Research Work with Special Emphasis on the 1st Method Following Rasatarangini
Abstract: Background: Ayurveda is an ancient healthcare system that influences many modern treatments. One of its key branches, Rasa Shastra, studies the health benefits of strong minerals and metals like mercury, sulphur, mica, and black bitumen. Among these, sulphur is critical for detoxification, blood purification, and digestion, being the third most common element in the human body after calcium and phosphorus. Before sulphur is used in Ayurvedic medicine, it must be …
Published in Research and Reviews : A Journal of Ayurvedic Science, Yoga and Naturopathy · Vol. 12, Issue 3, 2025 · pp. 1–11 Read article
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Graphene–Perovskite Hybrid Opto-Electronic Modulators for Ultra-Low Power Optical Communication
Abstract: This paper proposes a novel self-adaptive neuromorphic opto-electronic transceiver architecture designed to enhance the intelligence, adaptability, and efficiency of next-generation optical communication networks. The proposed system integrates neuromorphic computing principles with photonic signal processing to enable real-time learning, dynamic resource allocation, and autonomous compensation of channel impairments such as dispersion, nonlinearities, and noise. Unlike conventional transceivers, the developed model employs spiking neural networks embedded within opto-electronic circuits to mimic biological …
Published in Trends in Opto-electro & Optical Communication · Vol. 16, Issue 1, 2026 · pp. 41–52 Read article
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Synthesis and Characterization of PF-127 Stabilized Metformin Encapsulated Chitosan-TPP Nanoparticles
Abstract: Metformin is widely used to manage Type 2 Diabetes, but its effectiveness is limited by low intestinal absorption, high dose requirements, and a short half-life. To tackle these challenges, several nano-drug delivery systems have been designed to optimize the delivery of metformin and enhance its therapeutic efficacy. Nanoparticles (NPs) have emerged as key players in medicine, biology, and pharmacology, gaini considerable attention for their potential applications. Polymeric NPs are among …
Published in Nano Trends – A Journal of Nano Technology & Its Applications · Vol. 27, Issue 1, 2025 · pp. 34–38 Read article
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Thermal Conductivity and Energy Storage Performance of Paraffin Wax-Based Composites Reinforced with Amine Functionalized Graphene as a Nanofiller
Abstract: In this study, amine-functionalized graphene (AFG) was employed as a nanofiller/nanomaterial to enhance the thermal and structural properties of a paraffin wax (PW)-based polymeric composite, formulated as a phase change material (PCM). The PW/AFG composite was synthesized with varying nanofiller volume fractions (0.20%, 0.40%, 0.80%, and 1.60%), and its thermal conductivity, stability, and energy storage performance were systematically analyzed. The incorporation of AFG into the polymer matrix significantly improved the …
Published in Journal of Polymer & Composites · Vol. 13, Issue 5, 2025 · pp. 355–374 Read article
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Sensory Psychology of Supergrain Bakery: Consumer Perception Beyond Taste
Abstract: Bakery products remain a cornerstone of diets worldwide, yet wheat-based formulations are increasingly supplemented or replaced as consumers demand healthier, more functional alternatives. Supergrains such as quinoa, amaranth, millet, and cowpea, together with fruit-based flours such as guava flour, have been extensively investigated to enrich wheat-based products and improve their nutritional value. At the same time, the science of sensory psychology has become central to product acceptance, as taste, aroma, …
Published in International Journal of Nutritions · Vol. 3, Issue 2, 2026 Read article
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Effect of Sinusoidal and Inverse sinusoidal Load on the Vibration and Buckling Behaviour of Laminated Composite Symmetrical and Unsymmetrical Trapezoidal Panels
Abstract: Using finite element (FE) techniques, this work analyzes the influence of sinusoidal and invers sinusoidal stresses on the buckling behavior of trapezoidal laminated composite panels (also known as trapezoidal laminated composite panels). The discretization of the composite panel is accomplished by the use of an eight-noded iso-parametric plate element, which has five degrees of freedom for each node. Due to the incorporation of Higher Order Shear Deformation Theory (HOSDT) into …
Published in Journal of Polymer & Composites · Vol. 13, Issue 3, 2025 Read article
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Effect Of Sinusoidal and Inverse Sinusoidal Load on The Vibration and Buckling Behaviour of Laminated Composite Symmetrical and Unsymmetrical Trapezoidal Panels
Abstract: Using finite element (FE) techniques, this work analyzes the influence of sinusoidal and inverse sinusoidal stresses on the buckling behavior of trapezoidal laminated composite panels (also known as trapezoidal laminated composite panels). The discretization of the composite panel is accomplished by the use of an eight-noded iso-parametric plate element, which has five degrees of freedom for each node. Due to the incorporation of Higher Order Shear Deformation Theory (HOSDT) into …
Published in Journal of Polymer & Composites · Vol. 13, Issue 3, 2025 · pp. 72–84 Read article
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Gastro Retentive Drug Target System: Its Needs, Advantages, Limitation and Approaches
Abstract: Background: Gastro retentive drug delivery systems (GRDDS) address limitations of oral therapy for drugs with poor solubility, instability at intestinal pH, or narrow absorption windows by prolonging gastric residence and increasing contact with the gastric mucosa. Objectives: To review GRDDS approaches—floating systems, mucoadhesive systems, and super porous hydrogels—with emphasis on formulation strategies and polymer–excipient selection to enhance gastric retention, modulate buoyancy/swelling/adhesion, and ultimately improve oral bioavailability and therapeutic outcomes for …
Published in Trends in Drug Delivery · Vol. 13, Issue 2, 2026 Read article
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Accuracy Improvement for Propeller Cavitation Noise Prediction Using UDF
Abstract: Recently, there has been an increase in demand for propulsion systems with higher hydrodynamic performance and lower underwater-radiated noise, as environmental issues are gaining more attention in addition to the traditional military necessity. It is important to reduce cavitation noise when designing propellers of the ships, especially for oceanographic research vessels because they use acoustic instruments and cavitation noise can interfere with their operation. It is well known that, when …
Published in Journal of Experimental & Applied Mechanics · Vol. 16, Issue 2, 2025 · pp. 18–26 Read article
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Prediction of Mechanical Properties for Advanced Engineering Applications utilizing Polymer Composite Materials by Machine Learning
Abstract: Polymer composites show great promise as engineering materials because of their mechanical performance, resistance to corrosion, lightweight nature, and adaptability in design. Aerospace, automotive, biomedical, maritime, and civil engineers all rely on mechanical property prediction to cut down on trial expenses, expedite product development, and optimize material selection. Speedy design optimization is not possible using traditional numerical and experimental methods due to the high costs associated with material characterisation, computational …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 Read article
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IoT-Based Real-Time Monitoring System for Temperature and Humidity Control in Pharmaceutical Manufacturing
Abstract: Environmental conditions, especially temperature and humidity, play a vital role in pharmaceutical manufacturing processes. Even minor fluctuations in these parameters can significantly influence the stability, potency, and overall effectiveness of drug formulations. In many cases, uncontrolled environmental variations may lead to chemical degradation, reduced shelf life, contamination risks, and substantial financial losses for manufacturers. Therefore, maintaining precise and consistent environmental conditions is essential to ensure product quality, regulatory compliance, and …
Published in International Journal of Mobile Computing Technology · Vol. 4, Issue 1, 2026 · pp. 32–37 Read article
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Effect of Energy/Protein Ratio and Strain on Performance, Nutrient Digestibility and Serum Biochemical Indices of Exotic and Locally Adapted Turkey
Abstract: This study investigated the response of locally adapted and exotic turkeys raised under the same environmental conditions to diets with varying energy/protein ratio. One hundred and fourty-four (144) four-week old poults of each strain of turkey were randomly selected and assigned to six different diets in a 2 x 2 x 3 factorial arrangement. Each treatment diet were replicated twice with twelve (12) birds per replicate. Diets formulated with 28 …
Published in International Journal of Biochemistry and Biomolecule Research · Vol. 1, Issue 2, 2023 · pp. 37–45 Read article
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Effect of Span, Load Intensity, and Beam Geometry on Stress and Deflection Behavior of RCC Beams
Abstract: This study investigates the influence of variations in beam geometry, span, load intensity, and permissible stresses on the structural behavior of reinforced concrete beams. Using classical bending and shear stress formulations, the effects of a 20% increase in key parameters were analytically evaluated. Results indicate that a 20% increase in beam span leads to a proportional 20% increase in beam depth, whereas a 20% increase in beam width or permissible …
Published in Journal of Structural Engineering and Management · Vol. 13, Issue 1, 2026 · pp. 9–22 Read article
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Development and Performance Evaluation of Polymer-Modified Geopolymer Composites Incorporating GGBS
Abstract: This research investigates the development and performance of geopolymer-based composite materials formulated using Ground Granulated Blast Furnace Slag (GGBS) as a reactive mineral component within an aluminosilicate polymer matrix. The study aims to create an eco-efficient and structurally sound inorganic polymer composite comparable to M35-grade concrete, produced entirely under ambient curing conditions. A series of mixes with varying GGBS replacement ratios (0–100%) was prepared, maintaining a constant binder content of …
Published in Journal of Polymer & Composites · Vol. 14, Issue 2, 2026 · pp. 1145–1165 Read article
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Development of a Novel Analytical Framework for Investigating Non-Symmetric Deformation Behavior in Strip Rolling
Abstract: In recent years, the asymmetrical rolling process has attracted considerable research attention due to its ability to induce non-uniform deformation characteristics within metallic workpieces. In this context, the present study introduces a novel analytical framework for asymmetrical cold rolling based on an enhanced slab method, specifically designed to overcome the inherent limitations of existing analytical models when applied to a wide range of asymmetric rolling conditions. A newly developed mathematical …
Published in Journal of Experimental & Applied Mechanics · Vol. 17, Issue 1, 2026 · pp. 1–21 Read article
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Evaluating the Effect of NPSB Fertilizers on Barely (Hordeum vulgare L.) Production and Productivity at Tocha Woreda, Southwest Ethiopia.
Abstract: A number of blended fertilizers (BFs) were formulated and introduced but site and crop specific rate was not identified. A research was conducted in Tocha woreda to evaluate the rate of NPSB fertilizer to improve barely yield during main cropping season of 2019 and 2020. The experiment consists of seven treatment such as control(0) , recommended NP (69kg N and 20kg P), NPSB: 18.9-37.7-6.95-0.1 (100kg NPSB), NPSB: 41.9-37.7-6.95-0.1(100kg NPSB + …
Published in Research & Reviews : Journal of Botany · Vol. 13, Issue 3, 2024 · pp. 39–45 Read article
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Self-Healing Structural Polymer Composites Incorporating Bio-Inspired Nanofillers
Abstract: Self-healing polymer composites become an attractive family of intelligent materials that are capable of autonomously repairing damage, which will enhance their durability, reliability and service life in extreme engineering applications. The materials are based on the principles of nature, using the nanofillers that are derived from biological systems to improve mechanical properties and self-healing capabilities by utilizing hierarchical structures and multifunctional interface interactions. The recent developments on the formulation of …
Published in Journal of Polymer & Composites · Vol. 14, Issue 4, 2026 Read article
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Insulin : Comprehensive review on its Crucial Role in Metabolism and Disease Management
Abstract: Insulin's pivotal function lies in meticulously regulating blood sugar levels, thus guaranteeing cells access to the necessary energy for optimal functionality. When there is a rise in blood sugar, after a meal, the releases insulin gets released from the pancreas to facilitate the uptake of glucose by cells. Insulin primarily acts on muscle, fat, and liver cells, promoting the uptake of glucose from the blood. Another way to store glucose …
Published in International Journal of Virus Studies · Vol. 1, Issue 1, 2024 · pp. 37–43 Read article