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392 articles for “Ageing”
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Pharmacophore mapping, 3D QSAR, docking, and ADME prediction studies of novel Benzothiazinone derivatives
Abstract: Background Tuberculosis is a major public health concern worldwide which is caused by Mycobacterium tuberculosis. DprE1 (Decaprenyl Phosphoryl Ribose 2’- Epimerase) is the most challenging target for development of novel anti- tubercular agents because it is a small protein and located into cytoplasmic membrane. So, novel anti-TB drugs did not bound effectively with it. DprE1 catalyzes the oxidation of the 2’ hydroxyl group of DPR (Decaprenyl Phosphoryl D- Ribose) …
Published in International Journal of Antibiotics · Vol. 1, Issue 1, 2024 · pp. 59–82 Read article
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Intervertebral Disc Bulge in Young Individuals: Causes, Symptoms, and Remedies
Abstract: The prevalence of intervertebral disc bulge among younger individuals has raised concerns regarding its causes, symptoms, and potential remedies. This condition, typically associated with older age, has increasingly affected younger demographics. Understanding the causes behind this phenomenon is critical in addressing its impact on the younger population. The study delves into the key aspects related to intervertebral disc bulge among young individuals. The causes of intervertebral disc bulge in young …
Published in International Journal of Orthopedic Nursing and Practices · Vol. 1, Issue 2, 2023 · pp. 13–18 Read article
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Exploring Inclusivity: Challenges, Strategies, and Impact
Abstract: Inclusivity is a cornerstone which aims to create environments, products and systems that meet the diverse needs and abilities of all people. This research paper provides a comprehensive study of inclusivity and sheds light on its role in building a just and accessible world. It continues to trace the historical development of universal design, revealing key milestones and their impact on the pursuit of inclusivity. In addition, the article examines …
Published in International Journal of Rural and Regional Development · Vol. 1, Issue 2, 2023 · pp. 24–36 Read article
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Overview of Virulence Factor of Staphylococcus sp.
Abstract: Staphylococcus is a highly virulent genus of bacteria that can cause a range of infections in humans and animals. The production of toxins, enzymes, and biofilms contributes to its ability to establish infections and evade host defenses. Understanding the characteristics and virulence factors of Staphylococcus is crucial for the development of effective prevention strategies and treatment options. Staphylococcus aureus is a significant etiological agent of nosocomial infections on a global …
Published in International Journal of Toxins and Toxics · Vol. 1, Issue 1, 2024 · pp. 25–31 Read article
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Deciphering Th-Related Gene Interactions in Chronic Spontaneous Urticaria: Bioinformatics Insights and Drug Affinity Exploration
Abstract: Objective: There has been a great deal of interest in how inflammatory dermatosis and The cell interact, but the etiopathogenesis of chronic spontaneous urticaria (CSU) is still inadequately comprehended. Through bioinformatics techniques, the purpose of this work is to elucdate the molecular mechanism underlying Th-related genes in CSU and seeks to find the highest affinity drug. Methods: The CSU RNA expression profiling dataset provided the basis for the investigation. The …
Published in International Journal of Genetic Modifications and Recombinations · Vol. 2, Issue 1, 2024 · pp. 1–15 Read article
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A study conducted among young women living in specific locations of Honavar, Uttara Kannada, to evaluate their attitudes and knowledge about women abuse. With a view to organize a Mass Health Education Programme
Abstract: Worldwide and regional projections of violence against women indicate More than 25% of women in relationships between the ages of 15 and 49 report having experienced physical or sexual abuse at least once in their lifetime (since they were 15). Up to 38% of all female killings globally are the result of intimate relationship violence. Apart from domestic violence, 6% of women worldwide report experiencing sexual assault at the hands …
Published in International Journal of Brain Sciences · Vol. 1, Issue 1, 2024 · pp. 5–12 Read article
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Harnessing the Medicinal Potential of SwertiaChirata: A Phytochemical Strategy for Controlling Coronavirus Symptoms Like High Fever and Anxiety
Abstract: The current investigation focuses on exploring the therapeutic capacities of SwertiaChirata, colloquially known as Chirata, in managing the symptomatic displays of coronavirus infections. Chirata, a member of the Gentianaceae family, is a distinguished herb extensively used in Ayurvedic and Unani medicinal traditions, acknowledged for its myriad of healing qualities. In addition to its regular use in combating fever and loss of appetite, its prominent antioxidant traits position it as an …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 1, Issue 2, 2023 · pp. 27–31 Read article
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Coronary Vascular Disease: A General Review with Specific Reference to Etiology
Abstract: Cardiovascular disease (CVD), the foremost cause of mortality worldwide, has surged by 60% globally, reaching 20.5 million deaths in 2021 from 12.1 million in 1990, as per the latest report from the World Health Federation. While this increase is alarming on a global scale, it raises even greater concerns in countries like India where heart ailments are afflicting individuals at a younger age. The escalation of CVD among the younger …
Published in International Journal of Biomedical Innovations and Engineering · Vol. 2, Issue 1, 2024 · pp. 36–42 Read article
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Psychological Trauma Reflected in B.Rangarao’s Dalit Short Story Death of a Rich Man
Abstract: In the growing expansion of marginalized literature, B.Rangarao’s short story collection “Desperate Men and Women: Ten Dalit Short Stories from India” has been greatly applauded by the readers as it brilliantly exposed the trauma of both men and women of Dalit community in autocratic conditions in India. In Dalit writing Rangrao’s contribution gave fresh look especially to the short story genre as it is based on the revolutionary ideas of …
Published in Emerging Trends in Languages · Vol. 1, Issue 1, 2024 · pp. 01–07 Read article
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Nutraceuticals: Bridging Nutrition and Medicine for Future Wellness
Abstract: Nutraceuticals are items that can be classified as food or a component of food and provide medical or health benefits. This paper discusses the concept of nutraceuticals, their classification, and their role in promoting health and wellness. As of 2023, the worldwide nutraceuticals market is expected to be valued at approximately USD 317.22 billion, indicating a high rate of increase. Growth is projected to reach USD 626.02 billion by 2029 …
Published in Emerging Trends in Personalized Medicines · Vol. 1, Issue 2, 2024 · pp. 26–36 Read article
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Review of Control Strategies in Lower Extremity Exoskeleton
Abstract: Personal mobility is one of the biggest challenges for ensuring the quality of rehabilitation in the lives of Persons with Locomotor Disabilities (PwLDs) and old aged persons. In order to ensure effective orthotic rehabilitation, there is need to design and develop more and more automated aids and appliances. In order to know the status of research a study has been made on the controllers of lower limb exoskeleton (LLE). In …
Published in International Journal of Robotics and Automation in Mechanics · Vol. 1, Issue 2, 2023 · pp. 9–21 Read article
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An Assessment of Recent Initiatives for Financial Inclusion with Reference to Social Security Motto Jan Dhan to Jan Suraksha in India
Abstract: This research paper aims at assessing the recent initiatives by the Government of India with reference to the financial inclusion of common people in India. Financial freedom is one of the agents of economic growth of a country. Looking at the enormous amount of opportunities towards economic development in India, financial inclusion of people becomes necessary. Financial inclusion has been a matter of wide discussion amongst the policymakers and the …
Published in International Journal of Rural and Regional Development · Vol. 2, Issue 1, 2024 · pp. 01–05 Read article
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Multiple Sclerosis: A Brief Overview of the Disease, Its Pharmacotherapy
Abstract: Multiple Sclerosis is an autoimmune disorder mostly affecting individuals aged between 20-40. In this disorder, the optic, vertebral, and central nervous system nerves are primarily impacted. It is a neurological condition that worsens over time and is characterized by inflammation and the breakdown of the sheath that surrounds and shields the nerve fiber. Common symptoms may include muscle weakness, numbness, tingling, fatigue, vertigo, tremor, vision complications, pain, Lhermitte sign, sexual …
Published in International Journal of Brain Sciences · Vol. 1, Issue 1, 2024 · pp. 13–18 Read article
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Social Capital as a Predicting Indicator to Measure the Psychological Health Impacts of COVID-19 Pandemic on Urban Societies in Pakistan.
Abstract: The COVID-19 pandemic has forced people to adapt to massive changes in their lifestyles; from health to work and how they interact with everyone nearby they know. This study aims to investigate the psychological wellbeing-impacts of COVID-19 on social capital in Pakistan. Social capital means the social and cultural coherence (as a predicting indicator) in the society. This was a survey based study conducted in 5 major cities (Islamabad, Rawalpindi, …
Published in International Journal of Urban Design and Development · Vol. 2, Issue 1, 2024 · pp. 12–21 Read article
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Horizon Scanning and Early Assessment of Health Technologies for the Treatment of Orphan Diseases
Abstract: The theoretical foundations and regulatory framework of the processes of the formation of an effective health technology assessment (HTA) system at the early stages of the life cycle of medicines are analyzed in the article. Particular attention is paid to horizon scanning (HS) and early assessment of expensive innovative drugs utilized for treating rare diseases. In order to inform policymakers, purchasers, and providers (to prioritize MT research, financial, and operational …
Published in International Journal of Brain Sciences · Vol. 1, Issue 1, 2024 · pp. 32–39 Read article
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Assessing ESL Learners in Narrative Writing with Gamification through Storium: A Quantitative Study
Abstract: The purpose of this study was to investigate the use of the gamification approach from Storium to improve the narrative writing abilities of students learning English as a Second Language (ESL). Learners generate an interest in both studying and playing. Also, the study investigates the evaluation and practicability of gamification for English as a Second Language (ESL) students. The present study employs quantitative research method to study the findings. They …
Published in Recent Trends in Social Studies · Vol. 1, Issue 1, 2024 · pp. 41–49 Read article
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Organometallic Osmium Compounds in Cancer Therapy
Abstract: The exploration of organometallic complexes with osmium as potential anticancer agents was indeed an area of ongoing research. These complexes were being investigated for their unique properties and mechanisms of action against cancer cells. However, it’s essential to note that the field of scientific research is dynamic, and new findings may have emerged since then. Organometallic complexes with osmium can be designed to exhibit specific features that make them promising …
Published in International Journal of Advance in Molecular Engineering · Vol. 1, Issue 2, 2023 · pp. 01–25 Read article
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Navigating the Digital Frontier: An In-depth Analysis of Classroom Digitalization
Abstract: When we talk about the Internet, we think about the likes of social media, or platforms like Google which has an unfathomable archive of information which is available for any and every individual to use up to their own likings. However, there are several challenges and complexities associated with the Internet's impact on social interactions. The issues of online harassment, privacy, and the addictive nature of social media have become …
Published in International Journal of Electrical and Communication Engineering Technology · Vol. 1, Issue 2, 2023 · pp. 14–20 Read article
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Beyond Walls: The Transformative Power of Art Galleries in a Diverse Society
Abstract: Art galleries serve as dynamic spaces where artistic expression converges with cultural appreciation, fostering dialogue, reflection, and inspiration. This abstract explores the multifaceted role of art galleries in contemporary society, examining their significance as hubs of creativity, education, and community engagement. Through curate exhibitions, educational programs, and interactive experiences, galleries provide platforms for artists to showcase their works, audiences to explore diverse perspectives, and communities to connect with the transformative …
Published in Recent Trends in Social Studies · Vol. 1, Issue 1, 2024 · pp. 25–40 Read article
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Enhancing the User Experience of Asthma Inhalers: A Redesign Approach
Abstract: Asthma is a widespread chronic respiratory condition impacting millions globally, presenting significant challenges in its management and treatment. While conventional inhalers effectively administer medication, they often encounter usability issues, hindering patient adherence and treatment outcomes. This abstract delineates the development and potential impact of a redesigned asthma inhaler aimed at addressing these challenges. Incorporating human-centered design principles, the revamped inhaler prioritizes usability, portability, and effectiveness to enhance the overall management …
Published in International Journal of Solid State Innovations & Research · Vol. 1, Issue 2, 2023 · pp. 32–36 Read article