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1953 articles for “phosphoinositol-3-kinase pathway” (ranking capped at the first 2,000 matches — narrow the search to see the rest)
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Comprehensive Review on Pulsatile Drug Delivery System: Hybrid Approaches
Abstract: Pulsatile drug delivery systems (PDDS) represent a groundbreaking approach in pharmaceutical technology, allowing for controlled, targeted, and programmable drug release that aligns with circadian rhythms or caters to time-sensitive therapeutic requirements. Although traditional pulsatile systems have shown considerable clinical promise, their effectiveness is frequently compromised by physiological variations such as gastrointestinal transit times, changes in pH, and enzymatic activity. To tackle these obstacles, hybrid PDDS have been developed by combining …
Published in Trends in Drug Delivery · Vol. 13, Issue 1, 2026 · pp. 18–31 Read article
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An Ultraviolet-Curable Nano Cerium Oxide Coating and Its Anti Ultraviolet /Blue Light Properties
Abstract: An ultraviolet (UV)-curable nano cerium oxide (CeO2) coating with enhanced blue light and UV shielding properties, prepared using an ultrasonic blending method, is presented. This study systematically investigated the optimal synthesis conditions for nano CeO2, as well as the effects of UV intensity and CeO2 concentration on the curing kinetics and blue/UV light shielding performance of the UV-curable nanocomposite. The results indicate that the synthesized nano CeO2 exhibited improved mechanical …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 306–324 Read article
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Autonomous Drones for Search and Rescue Opera-tions: State of the Art and Future Prospects
Abstract: Autonomous drones have significantly transformed search and rescue (SAR) operations by improving the speed, precision, and overall effectiveness with which rescuers are able to locate and provide assistance to individuals in need. By leveraging state-of-the-art technologies such as computer vision, artificial intelligence (AI), machine learning, and advanced navigation systems, drones have proven invaluable in carrying out complex rescue missions. These technologies enable drones to navigate hazardous environments autonomously, even in …
Published in International Journal on Drones · Vol. 1, Issue 2, 2025 · pp. 9–13 Read article
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Deep Learning-Enhanced Polymer-Based Wearable Biosensors for Continuous Health Tracking via IoT
Abstract: The rapid proliferation of wearable biosensor technologies has transformed approaches to real-time health monitoring, yet challenges persist in achieving both mechanical robustness and reliable, continuous data analytics in dynamic environments. Conventional polymer-based sensing systems often fall short due to limited signal fidelity, inadequate adaptive analytics, or insufficient integration with secure, low-latency IoT frameworks. Addressing these deficiencies, this work introduces a flexible, deep learning-enhanced wearable biosensor platform that combines a nanostructured …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 18–31 Read article
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Dynamics of Prime Gap Sets: An Algorithmic and Set-Theoretic Approach
Abstract: In this paper, we present a theorem and an efficient algorithm for computing all prime numbers up to a given integer X. Our theorem establishes a relationship between the primes up to X and those up to (X+1)2, providing a theoretical foundation for the algorithm. The proposed method improves upon the traditional Sieve of Eratosthenes by dynamically eliminating multiples of primes using only the remaining numbers in the set, thereby …
Published in Research & Reviews: Discrete Mathematical Structures · Vol. 12, Issue 3, 2025 · pp. 20–25 Read article
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China’s Economic Performance (2020–2024): A Sectoral Index Analysis
Abstract: This study applies Laspeyres, Paasche, and Fisher ideal indices to China’s official 2020–2024 price and quantity data, quantifying sectoral inflation and real growth in agriculture, manufacturing, services, exports, and investment. Results show manufacturing experienced mild deflation (Laspeyres ≈ 98.7, implying ≈ 1.3% overall price decline) with a slight real output drop (~6.1%). A key driver was a sharp 21.4% fall in electric vehicle unit prices, despite +523% volume growth. Services …
Published in Research & Reviews: Discrete Mathematical Structures · Vol. 14, Issue 3, 2025 Read article
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Development of a Natural Fiber Sand–Carbon Composite Filter Using Agave sisalana for Sustainable Domestic Sewage Treatment
Abstract: This study presents an innovative approach to decentralized domestic sewage treatment by integrating Agave sisalana fibers as the core functional component within a composite filtration system. The filtration column was constructed using a vertical 1:3:1 layered configuration comprising silica sand (top), Agave sisalana fibers (middle), and activated carbon (bottom). Comprehensive experimental analyses were conducted to evaluate the system’s efficacy in removing key water quality parameters, including turbidity, total solids (TS), …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 43–51 Read article
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Innovative Design and Implementation of PCD-Based Drawing Dies and Tungsten Carbide Molds for Automotive Fastener Manufacturing
Abstract: This study presents an integrated engineering investigation into the design, optimization, and implementation of advanced tungsten carbide and polycrystalline diamond (PCD) tooling technologies within the cold forging and wire drawing processes at Koobesh Kavir Semnan Company, one of Iran’s leading automotive fastener manufacturers. By combining powder metallurgy principles, material flow simulation, and experimental validation, this research introduces a technological advancement that improves productivity, tool longevity, and cost-efficiency in industrial production. …
Published in Journal of Materials & Metallurgical Engineering · Vol. 15, Issue 3, 2025 · pp. 16–26 Read article
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Host Invasion to Immune Evasion: Emerging Concepts in Pathogen Virulence Strategies
Abstract: Pathogens have evolved a wide repertoire of virulence strategies that allow them to invade host tissues, establish infection, and circumvent immune responses. From the initial steps of adhesion and colonization to complex molecular mimicry, antigenic variation, and immunomodulation, pathogens display remarkable adaptability. While traditional research has emphasized host cell entry and toxin production, emerging evidence highlights subtler and more dynamic strategies such as manipulation of host signaling pathways, subversion of …
Published in International Journal of Pathogens · Vol. 2, Issue 2, 2025 Read article
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Sustainable Membrane Technologies for Environmental and Industrial Applications: A Review
Abstract: Membrane-based technologies have become indispensable in addressing global environmental and industrial challenges, including water scarcity, pollution control, and energy efficiency. While conventional membranes provide high selectivity and process efficiency, their sustainability is limited by factors such as fouling, high energy consumption, and end-of-life waste management. Recent advances in material science, nanotechnology, and bio-inspired design have led to the emergence of sustainable membranes with improved durability, lower environmental footprint, and broader …
Published in International Journal of Membranes · Vol. 2, Issue 2, 2025 · pp. 7–12 Read article
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Reinforcement Learning for Adaptive Sensing with Shape Memory Polymer-Based IoT Nodes
Abstract: The rapid expansion of intelligent sensing in the Internet of Things (IoT) has revealed the pressing need for materials and algorithms capable of self-adaptation in volatile environments. Conventional polymer-based sensors and static control strategies often fail to capture nonlinear thermo-mechanical dynamics, leaving them unsuitable for unpredictable operating conditions. Although prior studies have improved polymer composites or introduced algorithmic optimization independently, few attempts have coupled the adaptability of smart materials with …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 370–391 Read article
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Solar Wireless EV Charging System
Abstract: This project presents a Solar Wireless Electric Vehicle (EV) Charging System that integrates solar energy with inductive wireless power transfer (WPT) to achieve a sustainable and eco-friendly charging approach. The proposed system utilizes a 12V solar panel as the primary renewable energy source, which charges a 3.7V lithium-ion battery through a transistor-based control circuit. This stored solar energy then powers the primary coil, generating an alternating magnetic field that enables …
Published in International Journal of Electronics Automation · Vol. 3, Issue 2, 2025 · pp. 14–20 Read article
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Termite Mound Soil: A Potential Source of Biofertilizer in Koraput, Odisha
Abstract: Mass use of chemical fertilizers and extensive agriculture has reduced soil’s physiochemical properties and nutrient profile, generating crops with higher chemical residues, resulting unhealthy human population. Sustainable and cost effective nature friendly alternative methods of agriculture are the present need, to overcome the crisis. The study with Termite Mound Soil, TMS, in Koraput district of Odisha, India was performed to find nutrient composition and its potential as an ecofriendly, sustainable …
Published in Research and Reviews : Journal of Crop science and Technology · Vol. 14, Issue 3, 2025 · pp. 40–47 Read article
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Temperature-Dependent Viscoelastic Response of Magnetorheological Grease with Varying Particle Shapes
Abstract: This study examines the effect of temperatures on the magnetic and rheological properties of magnetorheological greases (MRGs) comprised of different particle shapes, under oscillatory shear mode test. Two samples were prepared with 70 wt.% flake-shaped electrolytic iron particles (EIP) and spherical carbonyl iron particles (CIP) which dispersed in 30 wt.% lithium-based grease, separately. Respective to magnetic properties test, the vibrating sample magnetometry (VSM) revealed that MRG-EIP exhibited 11.4% higher magnetic …
Published in Journal of Polymer & Composites · Vol. 13, Issue 6, 2025 · pp. 139–147 Read article
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Intelligent Management of Construction Projects: The Nexus of Human and Artificail Expertise
Abstract: Conversations about digitalization and artificial intelligence (AI) have continued to gain traction in the project management discourse. Although human expertise remains the hallmark of professionalism in the construction industry, AI has emerged as the newest wave of digital technological innovation, which can significantly elevate human productivity in the performance of project management functions. However, for project management professionals in the Nigerian construction industry, the potential of AI is both thrilling …
Published in Journal of Production Research & Management · Vol. 15, Issue 3, 2025 · pp. 16–24 Read article
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Development of Lightweight Chassis and Efficient Drivetrain for Formula Student Applications
Abstract: The chassis and drivetrain of a Formula Student vehicle are designed, analyzed, and optimized in this research study with an emphasis on manufacturability, performance, and safety. The project emphasizes the use of advanced engineering tools such as SolidWorks for computer-aided design (CAD) and ANSYS for structural analysis to evaluate the chassis under various dynamic conditions. The primary objective is to ensure that the driver remains safe inside the cockpit while …
Published in Journal of Automobile Engineering and Applications · Vol. 12, Issue 3, 2025 · pp. 1–17 Read article
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Integrated, Geospatial Risk Assessment of Air, Water, and Soil Pollution Impacts on Agricultural Sustainability using Advanced Digital Technologies
Abstract: The systemic threat posed by the convergence of air, water, and soil contaminants represents a critical challenge to global agricultural resilience and food security. Traditional, site-specific pollutant monitoring methods are insufficient for capturing the dynamic, diffuse, and often nonlinear nature of environmental risk pathways that permeate agrarian landscapes. This study presents a robust framework for comprehensive risk assessment utilizing a synergistic suite of modern tools designed for spatial, temporal, and …
Published in International Journal of Environmental Noise and Pollution Control · Vol. 3, Issue 2, 2025 · pp. 28–37 Read article
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Climate Change and Air Pollution Dynamics: Synergistic Effects and Mitigation Strategies
Abstract: Climate change and air pollution are deeply interlinked environmental problems that jointly exacerbate human health, ecosystem integrity, and economic well‑being. As global temperatures rise, shifts in meteorological conditions—such as increased heat, altered precipitation, and more frequent extreme weather events—modify pollutant generation, dispersion, chemical transformation, and removal processes. Meanwhile, many sources of air pollution are also sources of greenhouse gases (GHGs), giving rise to potential co‑benefits or trade‑offs when formulating mitigation …
Published in International Journal of Environmental Noise and Pollution Control · Vol. 3, Issue 2, 2025 · pp. 38–42 Read article
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Thermodynamic Optimization and Exergy-Based Performance Analysis of Hybrid Thermal Management Systems for Electric Vehicles
Abstract: The transition toward sustainable transportation has brought electric vehicles (EVs) to the forefront of modern engineering innovation. Despite their environmental benefits and improved energy efficiency, EVs face major thermal challenges that affect performance, safety, and durability. Efficient thermal management of batteries, power electronics, and electric drive systems is vital to ensure reliability under diverse operating conditions. This study presents a detailed thermodynamic optimization and exergy-based performance analysis of hybrid thermal …
Published in International Journal of Energy and Thermal Applications · Vol. 3, Issue 2, 2025 · pp. 19–23 Read article
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Epidemiology, Risk Factors, And Prevention Of Typhoid Fever In North India: A Regional Perspective
Abstract: Introduction: Typhoid fever, caused by Salmonella enterica serovar Typhi, remains a major public health concern, particularly in low- and middle-income countries. The disease is transmitted through contaminated food and water, leading to significant morbidity and mortality. Understanding its epidemiology, associated risk factors, and preventive measures is essential for effective control and management. This study aims to provide a comprehensive analysis of typhoid fever's prevalence, risk factors, and recommended interventions, with …
Published in Research and Reviews : A Journal of Immunology · Vol. 15, Issue 3, 2025 Read article