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1680 articles for “BCS Class II/IV drugs”
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Comparison of Models of Machine Learning and Hyperparameter optimization methods on various datasets
Abstract: The most likely phase in achieving powerful and robust machine learning models is probably the hyperparameters tuning step. The traditional exhaustive methods of search (Grid Search and others) ensure that the search space is covered, but are computationally very inexpensive; random search is less expensive and can still miss good regions; and lastly, the modern model-based and population-based methods (Bayesian Optimization, Tree-structured Parzen Estimator (TPE), Genetic Algorithms) are thought to …
Published in Recent Trends in Programming languages · Vol. 13, Issue 1, 2026 Read article
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A Comprehensive Study of Natural Language Processing Systems Using Modern Programming Languages: Techniques, Architectures, Experimental Evaluation, and Applications
Abstract: Natural Language Processing is a key field of study within artificial intelligence that focuses on enabling machines to understand and work with human language. This is because there is much digital text data everywhere. Natural Language Processing is what this study is about. It looks at new ways of doing Natural Language Processing. The old ways are like machine learning and the new ways are like learning. This study compares …
Published in Recent Trends in Programming languages · Vol. 13, Issue 1, 2026 Read article
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The Tech That Makes Space Travel Possible: From Earth to Orbit
Abstract: Space flight was once only a dream, but it has now become one of the most important achievements of modern science and engineering. This article looks at the technology that make it possible to travel from Earth to orbit, with a focus on the complex systems that make space missions safe, efficient, and repeatable. It looks at how rocket propulsion has changed throughout time, from classic chemical engines to new …
Published in Research & Reviews : Journal of Space Science & Technology · Vol. 15, Issue 1, 2026 · pp. 26–33 Read article
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An Overview on Intelligent Operating Systems (iOS)
Abstract: The rapid convergence of artificial intelligence techniques with core operating system services is ushering in a new class of platforms—Intelligent Operating Systems (Intelligent OS)—that can anticipate, adapt, and optimize on behalf of both applications and users. This paper surveys the architectural shifts required to embed learning, reasoning, and self healing capabilities into the kernel, scheduler, memory manager, and I/O subsystems. We present a prototype framework, NeuroKernel, that augments traditional OS …
Published in Journal of Operating Systems Development & Trends · Vol. 13, Issue 1, 2026 Read article
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SmartTrack : Advanced Attendence System using LR RFID
Abstract: This project presents the design and implementation of a long-range RFID attendance system aimed at transforming how educational institutions track attendance by making the process faster, more accurate, and completely contactless. Tradi- tional methods, whether manual roll calls or short-range RFID scanners, often interrupt class routines and leave room for errors or proxy attendance. To address these issues, the proposed system integrates long-range RFID readers, beam sensors, and ESP32 microcontrollers …
Published in Journal of Semiconductor Devices and Circuits · Vol. 13, Issue 1, 2026 Read article
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The Next Era of Nuclear Engineering: Beyond Fission
Abstract: Nuclear engineering is going through a big change as new technologies strain the limits of classical fission-based power generation. This article talks about the future generation of nuclear technologies, such as new reactor designs, small modular reactors (SMRs), and the growing potential of nuclear fusion. It looks at how these changes are meant to make nuclear energy safer, use less fuel, and create less long-lived radioactive waste, which are all …
Published in Journal of Nuclear Engineering & Technology · Vol. 16, Issue 1, 2026 · pp. 35–41 Read article
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Fundamental Principles of Fluid Behavior and Emerging Trends in Modern Fluid Mechanics Research
Abstract: Fluid behavior forms the foundation of numerous engineering technology and scientific applications, including aerospace flows, energy systems, and environmental processes. This paper presents a comprehensive overview of the fundamental principles governing fluid behavior, with a strong emphasis on their relevance to recent trends in fluid mechanic’s research. Core concepts such as fluid statics, fluid dynamics, and conservation laws are discussed to establish a solid theoretical framework. The study further examines …
Published in Recent Trends in Fluid Mechanics · Vol. 13, Issue 1, 2026 · pp. 14–21 Read article
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Formulation Challenges in Long-acting Injectable Small Molecules: Emerging Strategies and Perspectives
Abstract: Long-acting injectable (LAI) formulations represent a transformative approach in pharmacotherapy, particularly for conditions demanding sustained drug exposure over weeks to months. Although biologics have dominated this space historically, the adaptation of LAI technology to small molecules presents a distinct and complex set of challenges rooted in physicochemical properties, manufacturing scalability, and regulatory expectations. This review systematically addresses the principal formulation barriers encountered in developing LAI small-molecule products, including aqueous solubility …
Published in Research & Reviews: A Journal of Drug Design & Discovery · Vol. 13, Issue 2, 2026 Read article
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The Renaissance and Resilience of CB1 Reverse Agonists: From Central Liabilities to Peripheral Promise
Abstract: Building upon these foundational insights, current research has increasingly focused on refining the pharmacological profile of CB1 reverse agonists to maximize therapeutic benefit while minimizing central adverse effects. The adverse neuropsychiatric outcomes associated with first-generation agents such as Rimonabant including anxiety, depression, and suicidal ideation highlighted the critical role of central CB1 receptors in mood regulation. Consequently, drug development strategies have shifted toward peripherally restricted CB1 reverse agonists that exhibit …
Published in International Journal of Cheminformatics · Vol. 4, Issue 1, 2026 · pp. 30–35 Read article
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A Low-Cost Multi-Sensor IoT System for Real-Time Segregation of Polymer Waste
Abstract: Segregation of solid waste is a critical aspect of waste management, especially in settings where technical and financial constraints limit the adoption of sophisticated technologies. The proposed low cost, sensor-driven smart waste sorting system combines a variety of sensing technologies with an integrated decision-making system. The system employs an inductive sensor, moisture sensor and capacitive sensor to measure the physical properties of waste items, allowing segregation into metal, wet and …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 90–`107 Read article
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Physicochemical Transitions and Polymerization Dynamics in Multi-Generational Dentin Adhesives: A Critical Review of the Resin-Dentin Composite Interface
Abstract: Adhesive dentistry has undergone a transformative refinement over the past three decades, transitioning from technique-sensitive, multi-step etch-and-rinse protocols to streamlined universal formulations. This narrative review critically synthesizes evidence from thirty peer-reviewed investigations to evaluate the evolution of dentin bonding agents from the fourth through the eighth generations. The analysis places particular emphasis on the physicochemical dynamics of the resin-dentin interface, including interfacial bond strength metrics, marginal integrity, and microleakage behavior. …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 209–228 Read article
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A Study on High-Risk Pregnancy and Its Management: Role of Obstetric Nurses in Improving Maternal and Fetal Outcomes
Abstract: High-risk pregnancy is a major challenge in maternal and neonatal healthcare and is associated with increased morbidity and mortality among mothers and new-borns, particularly in developing regions where access to quality healthcare services remains uneven, this article examines the concept, classification, risk factors, pathophysiology, and management of high-risk pregnancy with a strong focus on the role of obstetric nurses in improving maternal and fetal outcomes, obstetric nurses play a central …
Published in International Journal of Midwifery Nursing And Practices · Vol. 4, Issue 1, 2026 · pp. 26–43 Read article
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Enhancement in Biomedical Polymer Nanocomposites: Biocompatibility and Mechanical Property Predictions using Machine Learning
Abstract: A machine learning (ML)-based framework is developed and validated through experimental analysis and comparative modeling to enhance system dependability and improve prediction performance. The proposed framework includes key stages such as data preprocessing, feature evaluation, model training, and performance benchmarking to determine the most effective prediction technique. Several machine learning models were evaluated, including Ensemble models, Artificial Neural Networks (ANN), Decision Tree (DT), Random Forest (RF), Support Vector Machine (SVM), …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 275–296 Read article
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Enhanced Sustainable Concrete Mix Design Using LLMs and Advanced Machine Learning Techniques
Abstract: Large Language Models (LLMs) are emerging as transformative tools in materials science, offering human-like reasoning, zero-shot problem solving, and the ability to integrate fuzzy laboratory knowledge with structured data. This study extends and reinterprets the original systematic benchmark for using LLMs in sustainable concrete design, particularly for Alkali-Activated Concrete (AAC). We introduce an enhanced, multi-model framework combining LLM-based inverse design, Random Forest regression, Gaussian Process Regression (GPR), and a lightweight …
Published in Recent Trends in Civil Engineering & Technology · Vol. 16, Issue 2, 2026 Read article
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Systematic Review on: Peptic Ulcer and Its Management
Abstract: Peptic ulcer disease (PUD), which affects 5–10% of people worldwide, is still a significant global health concern. Gastric acid and pepsin's corrosive effects cause mucosal injury in the stomach, duodenum, or lower oesophagus. Long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs) and Helicobacter pylori infection are the primary reasons. This review's goal is to examine PUD's aetiology, risk factors, pathophysiology, clinical symptoms, diagnostic methods, and evidence-based treatment modalities. PubMed, Google Scholar, …
Published in Research and Reviews : A Journal of Life Sciences · Vol. 16, Issue 1, 2026 Read article
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Assessing Taila Bindu Pariksha as a Diagnostic and Prognostic test for Diabetes Mellitus
Abstract: Ayurveda has consistently emphasised on not just treatment of a disease but also how to diagnose it and further assess the prognosis. Ayurveda is blessed with different diagnostic tests which is broadly classified into Roga and Rogi Pariksha such as Ashtavidha Pariksha, Dashavidha Pariksha and Dwadashavidha Pariksha. These tests are used very rarely by just few Ayurvedic practioners as an important diagnostic and prognostic methods in different diseases. Taila Bindu …
Published in Journal of AYUSH: Ayurveda, Yoga, Unani, Siddha and Homeopathy · Vol. 15, Issue 2, 2026 Read article
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A Review on Artificial Intelligence Techniques for Analyzing Deforestation and Illegal Logging Using Satellite Imagery
Abstract: Deforestation and illegal logging remain critical environmental threats, driving biodiversity loss, climate change, and socio-economic disruption. Conventional monitoring techniques frequently do not yield real-time, large-scale insights. Recent developments in Artificial Intelligence (AI), especially in deep learning and computer vision, have revolutionized the ability to analyze high-resolution satellite images for detecting deforestation and monitoring illegal logging. This review synthesizes recent developments in AI-driven approaches, highlighting convolutional neural networks (CNNs), anomaly detection …
Published in International Journal of Satellite Remote Sensing · Vol. 4, Issue 1, 2026 · pp. 1–9 Read article
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Time Multiplexed Binary Offset Carrier (TMBOC) Transmitter with Polarimetric Interferometric Synthetic Aperture Radar (Pol-InSAR)
Abstract: This paper provides insights into Time Multiplexed Binary Offset Carrier (TMBOC), a modulation technique employed in satellite navigation systems, specifically designed for GPS L1C. TMBOC improves signal correlation properties by time-multiplexing Binary Offset Carrier (BOC) (1, 1) and (6, 1). The text discusses various TMBOC models, including spectral representations and power distributions. Performance analysis reveals the potential of TMBOC signals in achieving superior tracking accuracy and interference resistance compared to …
Published in International Journal of Satellite Remote Sensing · Vol. 4, Issue 1, 2026 · pp. 34–49 Read article
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An AI-Driven IoT Framework for Autonomous Quality Assurance in Optical Lens Manufacturing
Abstract: The evolution of high-precision optics—ranging from smartphone micro-lenses to high-end astronomical glass—demands unprecedented accuracy in manufacturing. Traditional inspection methods, reliant on manual sampling or static automated optical inspection (AOI), often fail to bridge the gap between high-speed production and the detection of microscopic surface aberrations. This paper introduces an integrated architecture combining the Internet of Things (IoT) and Deep Learning-based decision-making systems to revolutionize lens quality control. By deploying an …
Published in International Journal of Optical Innovations & Research · Vol. 4, Issue 1, 2026 · pp. 36–41 Read article
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Critical Review on Multifunctional Polymer Composites for Weight Reduction and AI Based Battery Thermal Management in Electric Vehicles
Abstract: The rapid growth of electric vehicles (EVs) has intensified the need for advanced materials and intelligent control systems capable of improving energy efficiency, driving range, thermal safety, and overall vehicle sustainability. This paper presents a critical review of multifunctional polymer composites and artificial intelligence-based battery thermal management systems (AI-BTMS) for next-generation EV applications. Polymer composites reinforced with carbon fibers, graphene, boron nitride, nanoclays, and carbon nanotubes offer significant advantages over …
Published in Journal of Polymer & Composites · Vol. 14, Issue 3, 2026 · pp. 603–619 Read article